What airlines fly to South America?

American Airlines, Delta and LATAM Airlines are the top three most popular airlines that fly to South America from Portland according to our data. American Airlines is the first choice among our users, with 28% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 5 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Portland to South America?

Delta and Air Canada are the most popular carriers operating from Portland to South America

When did momondo last update prices for flights from Portland Airport to South America?

Prices for flights from Portland Airport to South America are refreshed on a daily basis.

How many operators does momondo search for flights from Portland Airport to South America?

There are 4 operators available for flights from Portland Airport to South America as of December 2025.

How old do you have to be to fly from Portland Airport to South America?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$190 Cheap Flights from Portland to South America in 2025/26

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Find the cheapest flights from Portland to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:25 am - 6:55 am

PDX

UIO

20h 30m1 stop

4:00 am - 8:01 pm

UIO

PDX

18h 01m2 stops

$443Multiple Airlines

Mon, Mar 2 - Tue, Mar 10

7:25 am - 6:55 am

PDX

UIO

20h 30m1 stop

5:20 pm - 8:33 pm

UIO

PDX

29h 13m1 stop

$474Multiple Airlines

Mon, Mar 2 - Tue, Mar 10

7:05 am - 6:55 am

PDX

UIO

20h 50m1 stop

5:20 pm - 8:43 pm

UIO

PDX

30h 23m1 stop

$477Multiple Airlines

Sun, Jan 25 - Mon, Feb 2

9:45 pm - 2:17 pm

PDX

CTG

13h 32m1 stop

5:05 am - 10:09 pm

CTG

PDX

19h 04m2 stops

$655Delta

Tue, Mar 3 - Tue, Mar 10

7:11 pm - 2:17 pm

PDX

CTG

16h 06m2 stops

2:30 pm - 10:01 am

CTG

PDX

21h 31m2 stops

$656Delta

Tue, Mar 3 - Tue, Mar 10

7:10 am - 11:00 pm

PDX

CTG

12h 50m2 stops

3:02 pm - 8:43 pm

CTG

PDX

32h 41m2 stops

$695United Airlines

Mon, Feb 23 - Wed, Feb 25

7:10 am - 11:00 pm

PDX

CTG

12h 50m2 stops

3:02 pm - 8:43 pm

CTG

PDX

32h 41m2 stops

$705United Airlines

Tue, Feb 24 - Sun, Mar 1

6:25 am - 5:35 am

PDX

SCL

18h 10m1 stop

11:55 pm - 12:02 pm

SCL

PDX

17h 07m1 stop

$891LATAM Airlines

Tue, Feb 3 - Tue, Mar 3

7:00 am - 5:55 am

PDX

SCL

18h 55m1 stop

11:55 pm - 12:14 pm

SCL

PDX

16h 19m1 stop

$912LATAM Airlines

Mon, Mar 9 - Thu, Mar 19

11:01 pm - 10:15 am

PDX

MVD

30h 14m1 stop

11:05 pm - 8:27 pm

MVD

PDX

26h 22m2 stops

$991American Airlines

Tue, Jan 20 - Tue, Feb 3

United Airlines flights from Portland to South America

Our best United Airlines deals on Portland to South America flight tickets

United Airlines

May 5

PDX7:00 amPortland

14h 25m

1 stop

UIO11:25 pmQuito Mariscal Sucr

May 13

UIO12:35 amQuito Mariscal Sucr

20h 52m

1 stop

PDX7:27 pmPortland

$675

Find similar

United Airlines

Feb 17

PDX7:10 amPortland

14h 20m

1 stop

UIO12:30 amQuito Mariscal Sucr

Mar 2

UIO1:35 amQuito Mariscal Sucr

24h 29m

2 stops

PDX11:04 pmPortland

$679

Find similar

United Airlines

Feb 15

PDX1:40 pmPortland

29h 55m

2 stops

BOG10:35 pmBogotá El Dorado

Feb 24

BOG8:15 amBogotá El Dorado

19h 19m

2 stops

PDX12:34 amPortland

$684

Find similar

American Airlines flights from Portland to South America

Our best American Airlines deals on Portland to South America flight tickets

American Airlines

Jan 13

PDX11:01 pmPortland

12h 14m

1 stop

BOG2:15 pmBogotá El Dorado

Jan 20

BOG11:55 pmBogotá El Dorado

14h 50m

1 stop

PDX11:45 amPortland

$689

Find similar

American Airlines

Mar 1

PDX10:53 pmPortland

11h 37m

1 stop

CTG1:30 pmCartagena Rafael Nunez

Mar 7

CTG2:30 pmCartagena Rafael Nunez

12h 20m

1 stop

PDX11:50 pmPortland

$706

Find similar

American Airlines

Mar 1

PDX10:53 pmPortland

13h 37m

1 stop

CTG3:30 pmCartagena Rafael Nunez

Mar 7

CTG4:30 pmCartagena Rafael Nunez

20h 18m

2 stops

PDX9:48 amPortland

$711

Find similar

Fly from

Fly to

Route

Depart

Return

Price

PortlandQuito

PDX - UIO

PDXUIO

Portland

Mon 3/2

7:25 am-6:55 am

1 stop20h 30m

Quito Mariscal Sucr

Tue 3/10

4:00 am-8:01 pm

2 stops18h 01m

$443

PortlandQuito

PDX - UIO

PDXUIO

Portland

Mon 3/2

7:25 am-6:55 am

1 stop20h 30m

Quito Mariscal Sucr

Tue 3/10

5:20 pm-8:33 pm

1 stop29h 13m

$474

PortlandQuito

PDX - UIO

PDXUIO

Portland

Sun 1/25

7:05 am-6:55 am

1 stop20h 50m

Quito Mariscal Sucr

Mon 2/2

5:20 pm-8:43 pm

1 stop30h 23m

$477

PortlandCartagena

PDX - CTG

PDXCTG

Portland

Tue 3/3

9:45 pm-2:17 pm

1 stop13h 32m

Cartagena Rafael Nunez

Tue 3/10

5:05 am-10:09 pm

2 stops19h 04m

$655

PortlandCartagena

PDX - CTG

PDXCTG

Portland

Tue 3/3

7:11 pm-2:17 pm

2 stops16h 06m

Cartagena Rafael Nunez

Tue 3/10

2:30 pm-10:01 am

2 stops21h 31m

$656

PortlandCartagena

PDX - CTG

PDXCTG

Portland

Mon 2/23

7:10 am-11:00 pm

2 stops12h 50m

Cartagena Rafael Nunez

Wed 2/25

3:02 pm-8:43 pm

2 stops32h 41m

$695

PortlandCartagena

PDX - CTG

PDXCTG

Portland

Tue 2/24

7:10 am-11:00 pm

2 stops12h 50m

Cartagena Rafael Nunez

Sun 3/1

3:02 pm-8:43 pm

2 stops32h 41m

$705

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 2/3

6:25 am-5:35 am

1 stop18h 10m

Santiago Arturo Merino Benitez

Tue 3/3

11:55 pm-12:02 pm

1 stop17h 07m

$891

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/9

7:00 am-5:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Thu 3/19

11:55 pm-12:14 pm

1 stop16h 19m

$912

PortlandMontevideo

PDX - MVD

PDXMVD

Portland

Tue 1/20

11:01 pm-10:15 am

1 stop30h 14m

Montevideo Carrasco

Tue 2/3

11:05 pm-8:27 pm

2 stops26h 22m

$991

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Portland to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Portland to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $789. If you aren’t able to travel during the month of February, then book flights to South America from Portland during September instead. Flights to South America in September, while not as cheap as those in February, still average around $796.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $901 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Portland for as low as $825 on momondo.

Can stopping save me money on Portland to South America flights?

You could potentially save up to 29% on your flight if you consider stops on a Portland to South America flight.

Cheap Portland to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to South America

Fastest flight time	11h 35m
Direct flights	None

The fastest flight from Portland to South America takes 11h 35m

There are no direct flights from Portland to South America. There are no popular flight routes from Portland to South America.

Search flight deals

When did momondo last update prices for flights from Portland Airport to South America?
Prices for flights from Portland Airport to South America are refreshed on a daily basis.
How many operators does momondo search for flights from Portland Airport to South America?
There are 4 operators available for flights from Portland Airport to South America as of December 2025.
How old do you have to be to fly from Portland Airport to South America?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Portland Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Portland to South America

Compare and see reviews for airlines that fly from Portland to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $493	Free Cancellation	Rating 7.9 8,017 reviews	Search Delta flights
LATAM Airlines	PriceFrom $565	Free Cancellation	Rating 7.5 1,896 reviews	Search LATAM Airlines flights
United Airlines	PriceFrom $586	Free Cancellation	Rating 7.4 9,121 reviews	Search United Airlines flights
American Airlines	PriceFrom $608	Free Cancellation	Rating 7.2 11,073 reviews	Search American Airlines flights
Air Canada	PriceFrom $731	Free Cancellation	Rating 7.1 10,564 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Portland to South America?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Portland to South America. momondo saves you time and could save you money on your trip.

Can I find flights from Portland to South America with flexible booking policies on momondo?

All flight searches from Portland to South America on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Portland to South America?

Once all potential Portland to South America flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Portland to South America right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to South America flights. All you need is a valid email address and we will do the rest; it is that quick and easy.