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Cheap flights from Portland to Knoxville from $152

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Portland to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:43 am - 8:49 pmPDX  Portland-TYS Knoxville McGhee Tyson
7h 06m1 stop Chicago O'Hare Intl
United Airlines Logo
6:00 am - 11:33 amTYS  Knoxville McGhee Tyson-PDX Portland
8h 33m1 stop Chicago O'Hare Intl
$363United Airlines
Wed, Sep 30 - Tue, Oct 6
American Airlines Logo
7:00 am - 4:42 pmPDX  Portland-TYS Knoxville McGhee Tyson
6h 42m1 stop Dallas/Fort Worth
American Airlines Logo
4:38 pm - 11:59 pmTYS  Knoxville McGhee Tyson-PDX Portland
10h 21m1 stop Chicago O'Hare Intl
$363American Airlines
Sat, Oct 3 - Sat, Oct 10
American Airlines Logo
11:57 am - 11:32 pmPDX  Portland-TYS Knoxville McGhee Tyson
8h 35m1 stop Dallas/Fort Worth
American Airlines Logo
5:32 pm - 10:10 pmTYS  Knoxville McGhee Tyson-PDX Portland
7h 38m1 stop Dallas/Fort Worth
$363American Airlines
Tue, Nov 3 - Thu, Nov 12
American Airlines Logo
1:12 pm - 11:59 pmPDX  Portland-TYS Knoxville McGhee Tyson
7h 47m1 stop Chicago O'Hare Intl
American Airlines Logo
5:32 pm - 10:10 pmTYS  Knoxville McGhee Tyson-PDX Portland
7h 38m1 stop Dallas/Fort Worth
$363American Airlines
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
11:30 pm - 11:30 amPDX  Portland-TYS Knoxville McGhee Tyson
9h 00m2 stops Chicago O'Hare Intl Washington, D.C. Dulles Intl
United Airlines Logo
6:45 am - 11:47 amTYS  Knoxville McGhee Tyson-PDX Portland
8h 02m1 stop Chicago O'Hare Intl
$368United Airlines
Tue, Nov 3 - Thu, Nov 12
United Airlines Logo
10:43 am - 8:49 pmPDX  Portland-TYS Knoxville McGhee Tyson
7h 06m1 stop Chicago O'Hare Intl
United Airlines Logo
10:42 am - 5:47 pmTYS  Knoxville McGhee Tyson-PDX Portland
10h 05m2 stops Chicago O'Hare Intl Denver Intl
$368United Airlines
Wed, Sep 30 - Tue, Oct 6
Southwest Logo
6:55 am - 7:45 pmPDX  Portland-TYS Knoxville McGhee Tyson
9h 50m2 stops Las Vegas Harry Reid Intl Nashville Intl
Southwest Logo
7:05 am - 8:20 pmTYS  Knoxville McGhee Tyson-PDX Portland
16h 15m2 stops Nashville Intl Denver Intl
$379Southwest
Tue, Nov 3 - Thu, Nov 12
Southwest Logo
8:50 am - 10:45 pmPDX  Portland-TYS Knoxville McGhee Tyson
10h 55m2 stops Phoenix Sky Harbor Intl Nashville Intl
Southwest Logo
5:25 pm - 10:40 pmTYS  Knoxville McGhee Tyson-PDX Portland
8h 15m1 stop Denver Intl
$398Southwest
Thu, Oct 29 - Mon, Nov 2
Delta Logo
5:49 pm - 9:34 amPDX  Portland-TYS Knoxville McGhee Tyson
12h 45m2 stops Seattle/Tacoma Intl Atlanta Hartsfield-Jackson
Delta Logo
5:40 am - 10:42 amTYS  Knoxville McGhee Tyson-PDX Portland
8h 02m1 stop Atlanta Hartsfield-Jackson
$448Delta
Sat, Oct 17 - Tue, Oct 20
Delta Logo
5:49 pm - 9:34 amPDX  Portland-TYS Knoxville McGhee Tyson
12h 45m2 stops Seattle/Tacoma Intl Atlanta Hartsfield-Jackson
Delta Logo
5:40 am - 11:49 amTYS  Knoxville McGhee Tyson-PDX Portland
9h 09m2 stops Atlanta Hartsfield-Jackson Seattle/Tacoma Intl
$454Delta
Sat, Oct 17 - Tue, Oct 20

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Delta flights from Portland to Knoxville

Our best Delta deals on Portland to Knoxville flight tickets
Delta
Oct 17
PDX5:49 pmPortland
12h 45m
2 stops
TYS9:34 amKnoxville McGhee Tyson
Oct 20
TYS5:40 amKnoxville McGhee Tyson
8h 02m
1 stop
PDX10:42 amPortland
$448
Delta
Oct 17
PDX5:49 pmPortland
12h 45m
2 stops
TYS9:34 amKnoxville McGhee Tyson
Oct 20
TYS5:40 amKnoxville McGhee Tyson
9h 09m
2 stops
PDX11:49 amPortland
$454
Delta
Sep 9
PDX11:35 amPortland
8h 39m
1 stop
TYS11:14 pmKnoxville McGhee Tyson
Sep 18
TYS5:40 amKnoxville McGhee Tyson
7h 58m
1 stop
PDX10:38 amPortland
$462

American Airlines flights from Portland to Knoxville

Our best American Airlines deals on Portland to Knoxville flight tickets
American Airlines
Oct 17
PDX1:12 pmPortland
7h 47m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
Oct 20
TYS6:55 pmKnoxville McGhee Tyson
8h 04m
1 stop
PDX11:59 pmPortland
$363
American Airlines
Oct 3
PDX11:08 pmPortland
10h 19m
2 stops
TYS12:27 pmKnoxville McGhee Tyson
Oct 10
TYS6:55 pmKnoxville McGhee Tyson
8h 04m
1 stop
PDX11:59 pmPortland
$377
American Airlines
Sep 30
PDX7:25 amPortland
9h 36m
1 stop
TYS8:01 pmKnoxville McGhee Tyson
Oct 5
TYS6:55 pmKnoxville McGhee Tyson
8h 04m
1 stop
PDX11:59 pmPortland
$396

momondo Fare Finder

 
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

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Price

Cheapest round-trip

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Wed 9/30

10:43 am-8:49 pm

1 stop7h 06m

Knoxville McGhee Tyson

Tue 10/6

6:00 am-11:33 am

1 stop8h 33m

$363

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Sat 10/3

7:00 am-4:42 pm

1 stop6h 42m

Knoxville McGhee Tyson

Sat 10/10

4:38 pm-11:59 pm

1 stop10h 21m

$363

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Tue 11/3

11:57 am-11:32 pm

1 stop8h 35m

Knoxville McGhee Tyson

Thu 11/12

5:32 pm-10:10 pm

1 stop7h 38m

$363
Quickest round-trip

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Thu 10/29

1:12 pm-11:59 pm

1 stop7h 47m

Knoxville McGhee Tyson

Mon 11/2

5:32 pm-10:10 pm

1 stop7h 38m

$363

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Tue 11/3

11:30 pm-11:30 am

2 stops9h 00m

Knoxville McGhee Tyson

Thu 11/12

6:45 am-11:47 am

1 stop8h 02m

$368

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Wed 9/30

10:43 am-8:49 pm

1 stop7h 06m

Knoxville McGhee Tyson

Tue 10/6

10:42 am-5:47 pm

2 stops10h 05m

$368

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Tue 11/3

6:55 am-7:45 pm

2 stops9h 50m

Knoxville McGhee Tyson

Thu 11/12

7:05 am-8:20 pm

2 stops16h 15m

$379

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Thu 10/29

8:50 am-10:45 pm

2 stops10h 55m

Knoxville McGhee Tyson

Mon 11/2

5:25 pm-10:40 pm

1 stop8h 15m

$398

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Sat 10/17

5:49 pm-9:34 am

2 stops12h 45m

Knoxville McGhee Tyson

Tue 10/20

5:40 am-10:42 am

1 stop8h 02m

$448

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Sat 10/17

5:49 pm-9:34 am

2 stops12h 45m

Knoxville McGhee Tyson

Tue 10/20

5:40 am-11:49 am

2 stops9h 09m

$454

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Portland to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Portland and Knoxville?

Prices are currently low for flights on this route.

Typical prices usually range from $383 to $620.
The lowest price recently found on this route was $363.

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Portland, with most prices found around $435. If you aren’t able to travel during the month of January, then book flights to Knoxville from Portland during September instead. Flights to Knoxville in September, while not as cheap as those in January, still average around $436.

How far in advance should I book a flight from Portland to Knoxville?

You are more likely to see cheaper flights to Knoxville from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $514 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Portland for as low as $399 on momondo.

How have Portland to Knoxville flight prices changed over time?

As of September 2026, prices for Portland to Knoxville flights are approximately 35% more expensive when compared to flights at the same time last year.

When to book flights from Portland to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Knoxville (PDX to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Knoxville

Best Price Found

$152

Fastest flight time

6h 17m

Direct flights

None
The best one-way flight to Knoxville from Portland in the past 72 hours is $152. The best round-trip flight deal from Portland to Knoxville found on momondo in the last 72 hours is $363.
The fastest flight from Portland to Knoxville takes 6h 17m
There are no direct flights from Portland to Knoxville. There are no popular flight routes from Portland to Knoxville.
Search flight deals

Frequently asked questions about flying from Portland to Knoxville

  • How far is Portland to Knoxville McGhee Tyson by plane?

    Portland and Knoxville McGhee Tyson are 2108.9 mi apart from one another. A reasonable flight in good conditions will take 6h 17m.

  • When did momondo last update prices for flights from Portland Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Portland Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Portland Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Portland Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland to Knoxville?

Best airlines flying from Portland to Knoxville

Compare and see reviews for airlines that fly from Portland to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $279Free CancellationRating
7.8
8,549 reviews
Search Delta flights
American AirlinesPriceFrom $328Free CancellationRating
7.1
12,042 reviews
Search American Airlines flights
United AirlinesPriceFrom $358Free CancellationRating
7.4
10,173 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Dandridge
Clinton
Lenoir City
Rockford
Jefferson City

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Knoxville?

It is quick and easy to find Portland to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Portland to Knoxville with flexible booking policies on momondo?

Flights from Portland to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Portland to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Portland. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Portland to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Portland and alert you when they change.

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