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Cheap flights from Portland to Knoxville from $156

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Portland to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:13 pm - 11:02 amPDX  Portland-TYS Knoxville McGhee Tyson
8h 49m1 stop Chicago O'Hare Intl
American Airlines Logo
5:32 pm - 11:49 pmTYS  Knoxville McGhee Tyson-PDX Portland
9h 17m1 stop Dallas/Fort Worth
$311American Airlines
Thu, Dec 10 - Mon, Dec 14
American Airlines Logo
9:50 pm - 8:48 amPDX  Portland-TYS Knoxville McGhee Tyson
7h 58m1 stop Charlotte Douglas
American Airlines Logo
1:51 pm - 9:00 pmTYS  Knoxville McGhee Tyson-PDX Portland
10h 09m1 stop Charlotte Douglas
$311American Airlines
Thu, Nov 12 - Thu, Nov 19
United Airlines Logo
7:10 am - 4:54 pmPDX  Portland-TYS Knoxville McGhee Tyson
6h 44m1 stop Chicago O'Hare Intl
United Airlines Logo
5:28 pm - 11:15 pmTYS  Knoxville McGhee Tyson-PDX Portland
8h 47m1 stop Houston George Bush Intcntl
$311United Airlines
Tue, Jan 12 - Mon, Jan 25
United Airlines Logo
7:00 am - 5:00 pmPDX  Portland-TYS Knoxville McGhee Tyson
7h 00m1 stop Chicago O'Hare Intl
United Airlines Logo
6:00 am - 11:41 amTYS  Knoxville McGhee Tyson-PDX Portland
8h 41m1 stop Chicago O'Hare Intl
$311United Airlines
Sat, Dec 12 - Tue, Dec 15
United Airlines Logo
10:49 am - 8:47 pmPDX  Portland-TYS Knoxville McGhee Tyson
6h 58m1 stop Chicago O'Hare Intl
United Airlines Logo
6:00 am - 1:16 pmTYS  Knoxville McGhee Tyson-PDX Portland
10h 16m2 stops Chicago O'Hare Intl Denver Intl
$316United Airlines
Sat, Dec 12 - Tue, Dec 15
Southwest Logo
5:15 am - 6:35 pmPDX  Portland-TYS Knoxville McGhee Tyson
10h 20m2 stops Las Vegas Harry Reid Intl Nashville Intl
Southwest Logo
6:45 am - 2:00 pmTYS  Knoxville McGhee Tyson-PDX Portland
10h 15m2 stops Nashville Intl Phoenix Sky Harbor Intl
$322Southwest
Tue, Jan 12 - Mon, Jan 25
American Airlines Logo
10:00 pm - 9:55 amPDX  Portland-TYS Knoxville McGhee Tyson
8h 55m1 stop Charlotte Douglas
American Airlines Logo
5:32 pm - 11:49 pmTYS  Knoxville McGhee Tyson-PDX Portland
9h 17m1 stop Dallas/Fort Worth
$369American Airlines
Tue, Dec 1 - Mon, Dec 7
Southwest Logo
6:00 am - 7:50 pmPDX  Portland-TYS Knoxville McGhee Tyson
10h 50m2 stops Chicago Midway Nashville Intl
Southwest Logo
4:15 pm - 10:20 pmTYS  Knoxville McGhee Tyson-PDX Portland
9h 05m1 stop Denver Intl
$405Southwest
Tue, Dec 1 - Mon, Dec 7
Delta Logo
11:59 am - 11:11 pmPDX  Portland-TYS Knoxville McGhee Tyson
8h 12m1 stop Minneapolis St Paul
Delta Logo
5:10 pm - 10:10 pmTYS  Knoxville McGhee Tyson-PDX Portland
8h 00m1 stop Detroit Metropolitan Wayne County
$421Delta
Fri, Nov 13 - Sun, Nov 15
Delta Logo
11:10 pm - 10:01 amPDX  Portland-TYS Knoxville McGhee Tyson
7h 51m1 stop Atlanta Hartsfield-Jackson
Delta Logo
6:00 am - 10:56 amTYS  Knoxville McGhee Tyson-PDX Portland
7h 56m1 stop Atlanta Hartsfield-Jackson
$425Delta
Thu, Dec 17 - Thu, Jan 7

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Delta flights from Portland to Knoxville

Our best Delta deals on Portland to Knoxville flight tickets
Delta
Nov 13
PDX11:59 amPortland
8h 12m
1 stop
TYS11:11 pmKnoxville McGhee Tyson
Nov 15
TYS5:10 pmKnoxville McGhee Tyson
8h 00m
1 stop
PDX10:10 pmPortland
$421
Delta
Dec 17
PDX11:10 pmPortland
7h 51m
1 stop
TYS10:01 amKnoxville McGhee Tyson
Jan 7
TYS6:00 amKnoxville McGhee Tyson
7h 56m
1 stop
PDX10:56 amPortland
$425
Delta
Nov 7
PDX11:00 pmPortland
8h 54m
1 stop
TYS10:54 amKnoxville McGhee Tyson
Nov 11
TYS2:40 pmKnoxville McGhee Tyson
7h 34m
1 stop
PDX7:14 pmPortland
$487

Alaska Airlines flights from Portland to Knoxville

Our best Alaska Airlines deals on Portland to Knoxville flight tickets
Alaska Airlines
Nov 7
PDX7:08 amPortland
11h 31m
2 stops
TYS9:39 pmKnoxville McGhee Tyson
Nov 11
TYS2:55 pmKnoxville McGhee Tyson
11h 59m
2 stops
PDX11:54 pmPortland
$727
Alaska Airlines
Oct 26
PDX7:00 amPortland
8h 20m
1 stop
TYS6:20 pmKnoxville McGhee Tyson
Oct 29
TYS3:00 pmKnoxville McGhee Tyson
11h 54m
2 stops
PDX11:54 pmPortland
$892
Alaska Airlines
Oct 26
PDX9:29 pmPortland
10h 36m
2 stops
TYS11:05 amKnoxville McGhee Tyson
Oct 29
TYS4:38 pmKnoxville McGhee Tyson
10h 16m
2 stops
PDX11:54 pmPortland
$898

momondo Fare Finder

 
Use the filters below to find and compare flights from Portland to Knoxville that are best for you.

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Price

Cheapest round-trip

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Thu 12/10

11:13 pm-11:02 am

1 stop8h 49m

Knoxville McGhee Tyson

Mon 12/14

5:32 pm-11:49 pm

1 stop9h 17m

$311

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Thu 11/12

9:50 pm-8:48 am

1 stop7h 58m

Knoxville McGhee Tyson

Thu 11/19

1:51 pm-9:00 pm

1 stop10h 09m

$311
Quickest round-trip

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Tue 1/12

7:10 am-4:54 pm

1 stop6h 44m

Knoxville McGhee Tyson

Mon 1/25

5:28 pm-11:15 pm

1 stop8h 47m

$311

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Sat 12/12

7:00 am-5:00 pm

1 stop7h 00m

Knoxville McGhee Tyson

Tue 12/15

6:00 am-11:41 am

1 stop8h 41m

$311

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Sat 12/12

10:49 am-8:47 pm

1 stop6h 58m

Knoxville McGhee Tyson

Tue 12/15

6:00 am-1:16 pm

2 stops10h 16m

$316

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Tue 1/12

5:15 am-6:35 pm

2 stops10h 20m

Knoxville McGhee Tyson

Mon 1/25

6:45 am-2:00 pm

2 stops10h 15m

$322

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Tue 12/1

10:00 pm-9:55 am

1 stop8h 55m

Knoxville McGhee Tyson

Mon 12/7

5:32 pm-11:49 pm

1 stop9h 17m

$369

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Tue 12/1

6:00 am-7:50 pm

2 stops10h 50m

Knoxville McGhee Tyson

Mon 12/7

4:15 pm-10:20 pm

1 stop9h 05m

$405

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Fri 11/13

11:59 am-11:11 pm

1 stop8h 12m

Knoxville McGhee Tyson

Sun 11/15

5:10 pm-10:10 pm

1 stop8h 00m

$421

PortlandKnoxville

PDX Portland - TYS Knoxville McGhee Tyson

PDXTYS

Portland

Thu 12/17

11:10 pm-10:01 am

1 stop7h 51m

Knoxville McGhee Tyson

Thu 1/7

6:00 am-10:56 am

1 stop7h 56m

$425

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Portland to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Portland and Knoxville?

Prices are currently low for flights on this route.

Typical prices usually range from $440 to $761.
The lowest price recently found on this route was $311.

What is the cheapest month to fly to Knoxville?

The month of January is, on average, the cheapest month to fly to Knoxville from Portland, with most prices found around $414. If you aren’t able to travel during the month of January, then book flights to Knoxville from Portland during September instead. Flights to Knoxville in September, while not as cheap as those in January, still average around $444.

How far in advance should I book a flight from Portland to Knoxville?

You are more likely to see cheaper flights to Knoxville from Portland when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $520 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Portland for as low as $399 on momondo.

How have Portland to Knoxville flight prices changed over time?

As of October 2026, prices for Portland to Knoxville flights are approximately 71% more expensive when compared to flights at the same time last year.

When to book flights from Portland to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Knoxville (PDX to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Knoxville

Best Price Found

$156

Fastest flight time

6h 39m

Direct flights

None
The best one-way flight to Knoxville from Portland in the past 72 hours is $156. The best round-trip flight deal from Portland to Knoxville found on momondo in the last 72 hours is $311.
The fastest flight from Portland to Knoxville takes 6h 39m
There are no direct flights from Portland to Knoxville. There are no popular flight routes from Portland to Knoxville.
Search flight deals

Frequently asked questions about flying from Portland to Knoxville

  • How far is Portland to Knoxville McGhee Tyson by plane?

    Portland and Knoxville McGhee Tyson are 2108.9 mi apart from one another. A reasonable flight in good conditions will take 6h 39m.

  • When did momondo last update prices for flights from Portland Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Portland Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from Portland Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Portland Airport to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland to Knoxville?

Best airlines flying from Portland to Knoxville

Compare and see reviews for airlines that fly from Portland to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $279Free CancellationRating
7.8
8,678 reviews
Search Delta flights
American AirlinesPriceFrom $328Free CancellationRating
7.0
12,192 reviews
Search American Airlines flights
United AirlinesPriceFrom $358Free CancellationRating
7.3
10,432 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Crossville
Maryville
Murphy
Oak Ridge
Kodak
Lenoir City
Newport
Dandridge
Clinton
Rockford
Jefferson City

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Knoxville?

It is quick and easy to find Portland to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Portland to Knoxville with flexible booking policies on momondo?

Flights from Portland to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Portland to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Portland. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Portland to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Portland and alert you when they change.

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