What is the cheapest airline that flies from Portland to Knoxville McGhee Tyson?

Delta, American Airlines, and Southwest are the most popular carriers operating from Portland to Knoxville McGhee Tyson

What airlines fly to Knoxville?

American Airlines, Allegiant Air and Delta are the top three most popular airlines that fly to Knoxville from Portland, Maine according to our data. American Airlines is the first choice among our users, with 43% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 5 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Portland Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Portland Airport to Knoxville McGhee Tyson Airport refresh daily.

How many operators does momondo search for flights from Portland Airport to Knoxville McGhee Tyson Airport?

The number of operators available for flights from Portland Airport to Knoxville McGhee Tyson Airport is 3 as of December 2025.

How old do you have to be to fly from Portland Airport to Knoxville McGhee Tyson Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$140 Cheap Flights from Portland to Knoxville in 2025/26

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Find the cheapest flights from Portland, Maine to Knoxville

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 am - 11:12 am

PWM

TYS

5h 12m1 stop

6:10 am - 11:20 am

TYS

PWM

5h 10m1 stop

$233Delta

Thu, Jan 15 - Tue, Jan 20

5:20 am - 10:49 am

PWM

TYS

5h 29m1 stop

4:00 pm - 11:43 pm

TYS

PWM

7h 43m2 stops

$238American Airlines

Thu, Jan 15 - Tue, Jan 20

5:07 pm - 9:44 pm

PWM

TYS

4h 37m1 stop

6:00 am - 12:06 pm

TYS

PWM

6h 06m1 stop

$256American Airlines

Mon, Jan 12 - Thu, Jan 15

12:40 pm - 10:54 pm

PWM

TYS

10h 14m2 stops

6:00 am - 12:06 pm

TYS

PWM

6h 06m1 stop

$261American Airlines

Mon, Jan 12 - Thu, Jan 15

5:20 am - 10:49 am

PWM

TYS

5h 29m1 stop

7:44 am - 12:05 pm

TYS

PWM

4h 21m1 stop

$286American Airlines

Thu, Jan 15 - Mon, Jan 19

5:20 am - 10:49 am

PWM

TYS

5h 29m1 stop

8:09 am - 3:31 pm

TYS

PWM

7h 22m2 stops

$291American Airlines

Thu, Jan 15 - Tue, Jan 20

5:25 pm - 10:00 pm

PWM

TYS

4h 35m1 stop

7:40 am - 4:45 pm

TYS

PWM

9h 05m1 stop

$344Southwest

Sun, Mar 15 - Sun, Mar 22

8:40 am - 8:52 pm

PWM

TYS

12h 12m2 stops

6:45 am - 2:31 pm

TYS

PWM

7h 46m2 stops

$349United Airlines

Mon, Jan 12 - Thu, Jan 15

5:30 am - 9:00 pm

PWM

TYS

15h 30m2 stops

7:40 am - 4:45 pm

TYS

PWM

9h 05m1 stop

$381Southwest

Sun, Mar 15 - Sun, Mar 22

6:00 am - 4:53 pm

PWM

TYS

10h 53m2 stops

6:45 am - 2:39 pm

TYS

PWM

7h 54m1 stop

$392United Airlines

Thu, Jan 15 - Mon, Jan 19

Southwest flights from Portland, Maine to Knoxville

Our best Southwest deals on Portland, Maine to Knoxville flight tickets

Southwest

Mar 15

PWM5:25 pmPortland

4h 35m

1 stop

TYS10:00 pmKnoxville McGhee Tyson

Mar 22

TYS7:40 amKnoxville McGhee Tyson

9h 05m

1 stop

PWM4:45 pmPortland

$344

Find similar

Southwest

Mar 15

PWM5:30 amPortland

15h 30m

2 stops

TYS9:00 pmKnoxville McGhee Tyson

Mar 22

TYS7:40 amKnoxville McGhee Tyson

9h 05m

1 stop

PWM4:45 pmPortland

$381

Find similar

Southwest

Mar 15

PWM5:30 amPortland

15h 30m

2 stops

TYS9:00 pmKnoxville McGhee Tyson

Mar 22

TYS1:35 pmKnoxville McGhee Tyson

10h 30m

2 stops

PWM12:05 amPortland

$509

Find similar

United Airlines flights from Portland, Maine to Knoxville

Our best United Airlines deals on Portland, Maine to Knoxville flight tickets

United Airlines

Jan 12

PWM8:40 amPortland

12h 12m

2 stops

TYS8:52 pmKnoxville McGhee Tyson

Jan 15

TYS6:45 amKnoxville McGhee Tyson

7h 46m

2 stops

PWM2:31 pmPortland

$349

Find similar

United Airlines

Jan 15

PWM6:00 amPortland

10h 53m

2 stops

TYS4:53 pmKnoxville McGhee Tyson

Jan 19

TYS6:45 amKnoxville McGhee Tyson

7h 54m

1 stop

PWM2:39 pmPortland

$392

Find similar

United Airlines

Jan 15

PWM6:00 amPortland

10h 53m

2 stops

TYS4:53 pmKnoxville McGhee Tyson

Jan 19

TYS6:45 amKnoxville McGhee Tyson

12h 05m

2 stops

PWM6:50 pmPortland

$397

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Portland, Maine to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 1/15

6:00 am-11:12 am

1 stop5h 12m

Knoxville McGhee Tyson

Tue 1/20

6:10 am-11:20 am

1 stop5h 10m

$233

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 1/15

5:20 am-10:49 am

1 stop5h 29m

Knoxville McGhee Tyson

Tue 1/20

4:00 pm-11:43 pm

2 stops7h 43m

$238

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Mon 1/12

5:07 pm-9:44 pm

1 stop4h 37m

Knoxville McGhee Tyson

Thu 1/15

6:00 am-12:06 pm

1 stop6h 06m

$256

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Mon 1/12

12:40 pm-10:54 pm

2 stops10h 14m

Knoxville McGhee Tyson

Thu 1/15

6:00 am-12:06 pm

1 stop6h 06m

$261

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 1/15

5:20 am-10:49 am

1 stop5h 29m

Knoxville McGhee Tyson

Mon 1/19

7:44 am-12:05 pm

1 stop4h 21m

$286

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 1/15

5:20 am-10:49 am

1 stop5h 29m

Knoxville McGhee Tyson

Tue 1/20

8:09 am-3:31 pm

2 stops7h 22m

$291

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Sun 3/15

5:25 pm-10:00 pm

1 stop4h 35m

Knoxville McGhee Tyson

Sun 3/22

7:40 am-4:45 pm

1 stop9h 05m

$344

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Mon 1/12

8:40 am-8:52 pm

2 stops12h 12m

Knoxville McGhee Tyson

Thu 1/15

6:45 am-2:31 pm

2 stops7h 46m

$349

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Sun 3/15

5:30 am-9:00 pm

2 stops15h 30m

Knoxville McGhee Tyson

Sun 3/22

7:40 am-4:45 pm

1 stop9h 05m

$381

PortlandKnoxville

PWM - TYS

PWMTYS

Portland

Thu 1/15

6:00 am-4:53 pm

2 stops10h 53m

Knoxville McGhee Tyson

Mon 1/19

6:45 am-2:39 pm

1 stop7h 54m

$392

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from Portland, Maine to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Portland, Maine, with most prices found around $288. If you aren’t able to travel during the month of August, then book flights to Knoxville from Portland, Maine during February instead. Flights to Knoxville in February, while not as cheap as those in August, still average around $323.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Portland, Maine to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $127. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Portland, Maine to Knoxville for around $218.

What is the cheapest time of day to depart on your flight to Knoxville?

In the morning is the cheapest time of day to fly from Portland, Maine to Knoxville when you can find flight prices for as low as $191. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $604.

When to book flights from Portland, Maine to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Portland, Maine to Knoxville (PWM to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Knoxville

Fastest flight time	4h 35m
Direct flights	None

The fastest flight from Portland, Maine to Knoxville takes 4h 35m

There are no direct flights from Portland, Maine to Knoxville. There are no popular flight routes from Portland, Maine to Knoxville.

Search flight deals

How far is Portland to Knoxville McGhee Tyson by plane?
There are 897.0 mi between Portland and Knoxville McGhee Tyson. 4h 35m is a normal flight duration for this route.
When did momondo last update prices for flights from Portland Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Portland Airport to Knoxville McGhee Tyson Airport refresh daily.
How many operators does momondo search for flights from Portland Airport to Knoxville McGhee Tyson Airport?
The number of operators available for flights from Portland Airport to Knoxville McGhee Tyson Airport is 3 as of December 2025.
How old do you have to be to fly from Portland Airport to Knoxville McGhee Tyson Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Portland Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents you'll need for your trip to Knoxville McGhee Tyson Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Portland, Maine to Knoxville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Portland, Maine to Knoxville is American Airlines (68% of total bookings). The next most popular airlines are Delta (23%) and United Airlines (9%).

Best airlines flying from Portland, Maine to Knoxville

Compare and see reviews for airlines that fly from Portland, Maine to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $258	Free Cancellation	Rating 7.2 11,054 reviews	Search American Airlines flights
Delta	PriceFrom $258	Free Cancellation	Rating 7.9 8,005 reviews	Search Delta flights
United Airlines	PriceFrom $424	Free Cancellation	Rating 7.4 9,091 reviews	Search United Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Maryville

Crossville

Murphy

Alcoa

Oak Ridge

Newport

Lenoir City

Kodak

Dandridge

Jefferson City

Clinton

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Knoxville?

It is quick and easy to find Portland to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Portland to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Portland with this policy.

How can momondo help me find flights from Portland to Knoxville?

momondo helps you find the best flight between Portland and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Portland to Knoxville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to Knoxville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.