Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Portland, Maine to Florence from $304

1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Portland, Maine to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
4:32 pm - 11:54 pmPWM  Portland-FLO Florence
7h 22m2 stops Philadelphia Charlotte Douglas
American Airlines Logo
2:35 pm - 11:57 pmFLO  Florence-PWM Portland
9h 22m2 stops Charlotte Douglas Washington, D.C. Reagan-National
$663American Airlines
Sat, Nov 21 - Fri, Nov 27
American Airlines Logo
5:26 am - 2:09 pmPWM  Portland-FLO Florence
8h 43m2 stops Washington, D.C. Reagan-National Charlotte Douglas
American Airlines Logo
2:35 pm - 11:57 pmFLO  Florence-PWM Portland
9h 22m2 stops Charlotte Douglas Washington, D.C. Reagan-National
$719American Airlines
Sun, Nov 22 - Fri, Nov 27
American Airlines Logo
5:45 am - 11:54 pmPWM  Portland-FLO Florence
18h 09m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 11:57 pmFLO  Florence-PWM Portland
9h 22m2 stops Charlotte Douglas Washington, D.C. Reagan-National
$826American Airlines
Sat, Nov 21 - Fri, Nov 27
American Airlines Logo
6:00 am - 2:09 pmPWM  Portland-FLO Florence
8h 09m2 stops Philadelphia Charlotte Douglas
American Airlines Logo
5:09 am - 2:40 pmFLO  Florence-PWM Portland
9h 31m2 stops Charlotte Douglas Philadelphia
$912American Airlines
Sat, Nov 21 - Sat, Nov 28
American Airlines Logo
6:00 am - 2:09 pmPWM  Portland-FLO Florence
8h 09m2 stops Philadelphia Charlotte Douglas
American Airlines Logo
5:09 am - 2:40 pmFLO  Florence-PWM Portland
9h 31m2 stops Charlotte Douglas Philadelphia
$968American Airlines
Sun, Nov 22 - Sat, Nov 28
American Airlines Logo
6:00 am - 3:09 pmPWM  Portland-FLO Florence
9h 09m2 stops Philadelphia Charlotte Douglas
American Airlines Logo
2:35 pm - 9:48 amFLO  Florence-PWM Portland
19h 13m2 stops Charlotte Douglas Washington, D.C. Reagan-National
$971American Airlines
Mon, Nov 16 - Fri, Nov 20
American Airlines Logo
5:45 am - 2:09 pmPWM  Portland-FLO Florence
8h 24m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 10:52 pmFLO  Florence-PWM Portland
8h 17m1 stop Charlotte Douglas
$995American Airlines
Sat, Nov 21 - Fri, Nov 27
American Airlines Logo
5:26 am - 2:09 pmPWM  Portland-FLO Florence
8h 43m2 stops Washington, D.C. Reagan-National Charlotte Douglas
American Airlines Logo
2:35 pm - 11:55 pmFLO  Florence-PWM Portland
9h 20m1 stop Charlotte Douglas
$1,031American Airlines
Sat, Nov 21 - Sat, Nov 28
American Airlines Logo
5:45 am - 2:09 pmPWM  Portland-FLO Florence
8h 24m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 11:55 pmFLO  Florence-PWM Portland
9h 20m1 stop Charlotte Douglas
$1,171American Airlines
Sat, Nov 21 - Sat, Nov 28
American Airlines Logo
7:10 am - 3:09 pmPWM  Portland-FLO Florence
7h 59m1 stop Charlotte Douglas
American Airlines Logo
2:35 pm - 9:48 amFLO  Florence-PWM Portland
19h 13m2 stops Charlotte Douglas Washington, D.C. Reagan-National
$1,424American Airlines
Mon, Nov 16 - Fri, Nov 20

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

American Airlines flights from Portland, Maine to Florence, South Carolina

Our best American Airlines deals on Portland, Maine to Florence, South Carolina flight tickets
American Airlines
Nov 21
PWM4:32 pmPortland
7h 22m
2 stops
FLO11:54 pmFlorence
Nov 27
FLO2:35 pmFlorence
9h 22m
2 stops
PWM11:57 pmPortland
$663
American Airlines
Nov 22
PWM5:26 amPortland
8h 43m
2 stops
FLO2:09 pmFlorence
Nov 27
FLO2:35 pmFlorence
9h 22m
2 stops
PWM11:57 pmPortland
$719
American Airlines
Nov 21
PWM5:45 amPortland
18h 09m
1 stop
FLO11:54 pmFlorence
Nov 27
FLO2:35 pmFlorence
9h 22m
2 stops
PWM11:57 pmPortland
$826

momondo Fare Finder

 
Use the filters below to find and compare flights from Portland, Maine to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandFlorence

PWM Portland - FLO Florence

PWMFLO

Portland

Sat 11/21

4:32 pm-11:54 pm

2 stops7h 22m

Florence

Fri 11/27

2:35 pm-11:57 pm

2 stops9h 22m

$663

PortlandFlorence

PWM Portland - FLO Florence

PWMFLO

Portland

Sun 11/22

5:26 am-2:09 pm

2 stops8h 43m

Florence

Fri 11/27

2:35 pm-11:57 pm

2 stops9h 22m

$719

PortlandFlorence

PWM Portland - FLO Florence

PWMFLO

Portland

Sat 11/21

5:45 am-11:54 pm

1 stop18h 09m

Florence

Fri 11/27

2:35 pm-11:57 pm

2 stops9h 22m

$826

PortlandFlorence

PWM Portland - FLO Florence

PWMFLO

Portland

Sat 11/21

6:00 am-2:09 pm

2 stops8h 09m

Florence

Sat 11/28

5:09 am-2:40 pm

2 stops9h 31m

$912

PortlandFlorence

PWM Portland - FLO Florence

PWMFLO

Portland

Sun 11/22

6:00 am-2:09 pm

2 stops8h 09m

Florence

Sat 11/28

5:09 am-2:40 pm

2 stops9h 31m

$968

PortlandFlorence

PWM Portland - FLO Florence

PWMFLO

Portland

Mon 11/16

6:00 am-3:09 pm

2 stops9h 09m

Florence

Fri 11/20

2:35 pm-9:48 am

2 stops19h 13m

$971
Quickest round-trip

PortlandFlorence

PWM Portland - FLO Florence

PWMFLO

Portland

Sat 11/21

5:45 am-2:09 pm

1 stop8h 24m

Florence

Fri 11/27

2:35 pm-10:52 pm

1 stop8h 17m

$995

PortlandFlorence

PWM Portland - FLO Florence

PWMFLO

Portland

Sat 11/21

5:26 am-2:09 pm

2 stops8h 43m

Florence

Sat 11/28

2:35 pm-11:55 pm

1 stop9h 20m

$1,031

PortlandFlorence

PWM Portland - FLO Florence

PWMFLO

Portland

Sat 11/21

5:45 am-2:09 pm

1 stop8h 24m

Florence

Sat 11/28

2:35 pm-11:55 pm

1 stop9h 20m

$1,171

PortlandFlorence

PWM Portland - FLO Florence

PWMFLO

Portland

Mon 11/16

7:10 am-3:09 pm

1 stop7h 59m

Florence

Fri 11/20

2:35 pm-9:48 am

2 stops19h 13m

$1,424

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

See travel insights to Florence from

How to get the cheapest flight ticket from Portland, Maine to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Portland to Florence?

American Airlines is the most popular carrier operating from Portland to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Delta and JetBlue are the top three most popular airlines that fly to Florence, South Carolina from Portland, Maine according to our data. American Airlines is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 8 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Portland, Maine to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Florence, South Carolina (PWM to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Florence, South Carolina

Best Price Found

$304

Fastest flight time

7h 22m

Direct flights

None
The best one-way flight to Florence, South Carolina from Portland, Maine in the past 72 hours is $304. The best round-trip flight deal from Portland, Maine to Florence, South Carolina found on momondo in the last 72 hours is $663.
The fastest flight from Portland, Maine to Florence, South Carolina takes 7h 22m
There are no direct flights from Portland, Maine to Florence, South Carolina. There are no popular flight routes from Portland, Maine to Florence, South Carolina.
Search flight deals

Frequently asked questions about flying from Portland, Maine to Florence, South Carolina

  • How far is Portland to Florence by plane?

    The straight-line distance from Portland to Florence is 828.2 mi. Typically, this will take 7h 22m by plane in normal conditions.

  • When did momondo last update prices for flights from Portland Airport to Florence Airport?

    Prices for flights from Portland Airport to Florence Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Portland Airport to Florence Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The travel and health documents required for your trip to Florence Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Florence Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Darlington
Lake City
Hartsville
Bennettsville

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Florence with flexible booking policies on momondo?

All flight searches from Portland to Florence on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Portland to Florence?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Portland to Florence.

I’m not ready to book a flight from Portland to Florence right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Portland to Florence now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Florence and let you know when they change.

An easier way to manage your Florence, South Carolina trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 12/6
Sun 12/13
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States