Which airport is the most popular layover for flights between Portland, Maine and Des Moines?

Chicago (ORD) was the most common stop: 33% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from Portland, Maine to Des Moines?

Chicago (ORD) has the shortest average layover time for this route: 1h 08m.

Which layover airport offers the lowest fares from Portland, Maine to Des Moines?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $431.

Which layover airport has the shortest travel time from Portland, Maine to Des Moines?

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 5h 22m.

When did momondo last update prices for flights from Portland Airport to Des Moines Airport?

Prices for flights from Portland Airport to Des Moines Airport refresh daily.

How many operators does momondo search for flights from Portland Airport to Des Moines Airport?

There are 3 operators available for flights from Portland Airport to Des Moines Airport as of February 2026.

How old do you have to be to fly from Portland Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$180 Cheap Flights from Portland to Des Moines in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Portland, Maine to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:40 pm - 11:40 pm

PWM

DSM

7h 00m

1 stop

2:00 pm - 10:30 pm

DSM

PWM

7h 30m

1 stop

$347American Airlines

Mon, Mar 2 - Tue, Mar 10

5:40 pm - 11:40 pm

PWM

DSM

7h 00m

1 stop

2:00 pm - 10:30 pm

DSM

PWM

7h 30m

1 stop

$348American Airlines

Mon, Mar 2 - Tue, Mar 10

3:39 pm - 8:21 pm

PWM

DSM

5h 42m

1 stop

11:09 am - 11:27 pm

DSM

PWM

11h 18m

1 stop

$374American Airlines

Thu, Apr 16 - Sun, Apr 19

5:40 pm - 11:40 pm

PWM

DSM

7h 00m

1 stop

5:00 am - 6:04 pm

DSM

PWM

12h 04m

2 stops

$380American Airlines

Mon, Mar 2 - Tue, Mar 10

3:39 pm - 8:21 pm

PWM

DSM

5h 42m

1 stop

5:01 pm - 11:27 pm

DSM

PWM

5h 26m

1 stop

$383American Airlines

Thu, Apr 16 - Sun, Apr 19

5:40 pm - 9:01 am

PWM

DSM

16h 21m

1 stop

2:00 pm - 10:30 pm

DSM

PWM

7h 30m

1 stop

$395American Airlines

Thu, Feb 26 - Tue, Mar 3

5:40 pm - 11:40 pm

PWM

DSM

7h 00m

1 stop

5:00 am - 6:04 pm

DSM

PWM

12h 04m

2 stops

$414American Airlines

Mon, Mar 2 - Tue, Mar 10

6:00 am - 2:27 pm

PWM

DSM

9h 27m

2 stops

3:24 pm - 9:09 pm

DSM

PWM

4h 45m

1 stop

$416United Airlines

Thu, Feb 26 - Tue, Mar 3

6:00 am - 2:27 pm

PWM

DSM

9h 27m

2 stops

9:04 am - 11:20 pm

DSM

PWM

13h 16m

2 stops

$421United Airlines

Thu, Feb 26 - Tue, Mar 3

5:40 pm - 11:40 pm

PWM

DSM

7h 00m

1 stop

5:00 am - 6:04 pm

DSM

PWM

12h 04m

2 stops

$429American Airlines

Mon, Mar 2 - Tue, Mar 10

United Airlines flights from Portland, Maine to Des Moines

Our best United Airlines deals on Portland, Maine to Des Moines flight tickets

United Airlines

Feb 26

PWM6:00 amPortland

9h 27m

2 stops

DSM2:27 pmDes Moines

Mar 3

DSM3:24 pmDes Moines

4h 45m

1 stop

PWM9:09 pmPortland

$416

United Airlines

Feb 26

PWM6:00 amPortland

9h 27m

2 stops

DSM2:27 pmDes Moines

Mar 3

DSM9:04 amDes Moines

13h 16m

2 stops

PWM11:20 pmPortland

$421

United Airlines

Mar 2

PWM6:00 amPortland

33h 27m

2 stops

DSM2:27 pmDes Moines

Mar 10

DSM2:04 pmDes Moines

8h 00m

2 stops

PWM11:04 pmPortland

$527

American Airlines flights from Portland, Maine to Des Moines

Our best American Airlines deals on Portland, Maine to Des Moines flight tickets

American Airlines

Mar 2

PWM5:40 pmPortland

7h 00m

1 stop

DSM11:40 pmDes Moines

Mar 10

DSM2:00 pmDes Moines

7h 30m

1 stop

PWM10:30 pmPortland

$347

American Airlines

Mar 2

PWM5:40 pmPortland

7h 00m

1 stop

DSM11:40 pmDes Moines

Mar 10

DSM2:00 pmDes Moines

7h 30m

1 stop

PWM10:30 pmPortland

$348

American Airlines

Apr 16

PWM3:39 pmPortland

5h 42m

1 stop

DSM8:21 pmDes Moines

Apr 19

DSM11:09 amDes Moines

11h 18m

1 stop

PWM11:27 pmPortland

$374

momondo Fare Finder

Use the filters below to find and compare flights from Portland, Maine to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Mon 3/2

5:40 pm-11:40 pm

1 stop7h 00m

Des Moines

Tue 3/10

2:00 pm-10:30 pm

1 stop7h 30m

$347

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Mon 3/2

5:40 pm-11:40 pm

1 stop7h 00m

Des Moines

Tue 3/10

2:00 pm-10:30 pm

1 stop7h 30m

$348

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Thu 4/16

3:39 pm-8:21 pm

1 stop5h 42m

Des Moines

Sun 4/19

11:09 am-11:27 pm

1 stop11h 18m

$374

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Mon 3/2

5:40 pm-11:40 pm

1 stop7h 00m

Des Moines

Tue 3/10

5:00 am-6:04 pm

2 stops12h 04m

$380

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Thu 4/16

3:39 pm-8:21 pm

1 stop5h 42m

Des Moines

Sun 4/19

5:01 pm-11:27 pm

1 stop5h 26m

$383

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Thu 2/26

5:40 pm-9:01 am

1 stop16h 21m

Des Moines

Tue 3/3

2:00 pm-10:30 pm

1 stop7h 30m

$395

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Mon 3/2

5:40 pm-11:40 pm

1 stop7h 00m

Des Moines

Tue 3/10

5:00 am-6:04 pm

2 stops12h 04m

$414

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Thu 2/26

6:00 am-2:27 pm

2 stops9h 27m

Des Moines

Tue 3/3

3:24 pm-9:09 pm

1 stop4h 45m

$416

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Thu 2/26

6:00 am-2:27 pm

2 stops9h 27m

Des Moines

Tue 3/3

9:04 am-11:20 pm

2 stops13h 16m

$421

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Mon 3/2

5:40 pm-11:40 pm

1 stop7h 00m

Des Moines

Tue 3/10

5:00 am-6:04 pm

2 stops12h 04m

$429

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first

How to get the cheapest flight ticket from Portland, Maine to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Airlines

Layovers

What is the cheapest airline that flies from Portland to Des Moines?

American Airlines is the most popular carrier operating from Portland to Des Moines

What airlines fly to Des Moines?

American Airlines, Delta and Allegiant Air are the top three most popular airlines that fly to Des Moines from Portland, Maine according to our data. American Airlines is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 5 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When to book flights from Portland, Maine to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Portland, Maine to Des Moines (PWM to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Des Moines

Fastest flight time	6h 08m
Direct flights	None

The fastest flight from Portland, Maine to Des Moines takes 6h 08m

There are no direct flights from Portland, Maine to Des Moines. There are no popular flight routes from Portland, Maine to Des Moines.

Search flight deals

How far is Portland to Des Moines by plane?
Portland and Des Moines are 1192.1 mi apart from one another. Flights usually cover this in 6h 08m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Portland Airport to Des Moines Airport?
Prices for flights from Portland Airport to Des Moines Airport refresh daily.
How many operators does momondo search for flights from Portland Airport to Des Moines Airport?
There are 3 operators available for flights from Portland Airport to Des Moines Airport as of February 2026.
How old do you have to be to fly from Portland Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Portland, Maine to Des Moines?
Based on momondo bookings for flights between Portland, Maine and Des Moines, the leading airline is American Airlines, making up 46% of the total bookings. Other popular airlines include Delta with 42% and United Airlines with 12%.

Best airlines flying from Portland, Maine to Des Moines

Compare and see reviews for airlines that fly from Portland, Maine to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $229	Free Cancellation	Rating 7.9 8,176 reviews	Search Delta flights
American Airlines	PriceFrom $249	Free Cancellation	Rating 7.2 11,258 reviews	Search American Airlines flights
United Airlines	PriceFrom $319	Free Cancellation	Rating 7.4 9,263 reviews	Search United Airlines flights

West Des Moines

Ames

Ankeny

Altoona

Urbandale

Clive

Pella

Newton

Johnston

Boone

Osceola

Norwalk

Oskaloosa

Grinnell

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Des Moines?

Finding the right flight to Des Moines from Portland is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Portland to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Portland to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from Portland to Des Moines?

Once you have performed a search for Portland to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Portland to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Portland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Thu 3/12

Thu 3/19

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Nearby airports

Airlines

Cabin classes

Other United States destinations

Other flights from Portland, Maine

Complete your trip

Feeling lucky

Airports servicing Iowa

Sioux City Sioux Gateway Airport

Cheap flights from Portland, Maine to Des Moines from $180

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Des Moines departing on 3/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Portland, Maine to Des Moines

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

United Airlines flights from Portland, Maine to Des Moines

Our best United Airlines deals on Portland, Maine to Des Moines flight tickets

American Airlines flights from Portland, Maine to Des Moines

Our best American Airlines deals on Portland, Maine to Des Moines flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Portland, Maine to Des Moines that are best for you.

See travel insights to Des Moines from

How to get the cheapest flight ticket from Portland, Maine to Des Moines

What is the cheapest airline that flies from Portland to Des Moines?

American Airlines is the most popular carrier operating from Portland to Des Moines

What airlines fly to Des Moines?

Which airport is the most popular layover for flights between Portland, Maine and Des Moines?

Chicago (ORD) was the most common stop: 33% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Portland, Maine to Des Moines?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $431.

Which layover airport has the shortest travel time from Portland, Maine to Des Moines?

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 5h 22m.

Which layover airport has the shortest connection time from Portland, Maine to Des Moines?

Chicago (ORD) has the shortest average layover time for this route: 1h 08m.

When to book flights from Portland, Maine to Des Moines

Cheap Portland, Maine to Des Moines (PWM to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Des Moines

Fastest flight time

Direct flights

How far is Portland to Des Moines by plane?

When did momondo last update prices for flights from Portland Airport to Des Moines Airport?

How many operators does momondo search for flights from Portland Airport to Des Moines Airport?

How old do you have to be to fly from Portland Airport to Des Moines Airport?

What documentation or ID do you need to fly to Des Moines Airport?

What is the most popular airline from Portland, Maine to Des Moines?

Best airlines flying from Portland, Maine to Des Moines

Compare and see reviews for airlines that fly from Portland, Maine to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Des Moines?

Can I find flights from Portland to Des Moines with flexible booking policies on momondo?

How can momondo help me find flights from Portland to Des Moines?

I’m not ready to book a flight from Portland to Des Moines right now. Can momondo alert me if prices change?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa

Fly your favorite airline to Des Moines

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Des Moines

List of cabin classes available on flights landing in Des Moines. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Portland, Maine

According to popular flight searches on momondo this year

Complete your trip to Des Moines

Explore popular destinations other users love

According to popular flight searches on momondo this year