Which layover airport has the shortest travel time from Portland, Maine to Des Moines?

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 5h 19m.

Which airport is the most popular layover for flights between Portland, Maine and Des Moines?

Chicago (ORD) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Portland, Maine to Des Moines?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $431.

Which layover airport has the shortest connection time from Portland, Maine to Des Moines?

Chicago (ORD) has the shortest average layover time for this route: 1h 04m.

What is the cheapest airline that flies from Portland to Des Moines?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Portland to Des Moines

What airlines fly to Des Moines?

American Airlines, Delta and Allegiant Air are the top three most popular airlines that fly to Des Moines from Portland, Maine according to our data. American Airlines is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 5 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Portland Airport to Des Moines Airport?

Prices for flights from Portland Airport to Des Moines Airport refresh daily.

How many operators does momondo search for flights from Portland Airport to Des Moines Airport?

There are 3 operators available for flights from Portland Airport to Des Moines Airport as of July 2025.

How old do you have to be to fly from Portland Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$149 Cheap Flights from Portland to Des Moines in 2025

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Find the cheapest flights from Portland, Maine to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

7:44 am - 12:43 pmPWM-DSM

5h 59m1 stop

5:47 am - 1:54 pmDSM-PWM

7h 07m1 stop

$297American Airlines

Find Deal

Fri, Dec 5 - Mon, Dec 8

4:55 pm - 8:50 pmPWM-DSM

4h 55m1 stop

10:55 am - 11:07 pmDSM-PWM

11h 12m2 stops

$302Delta

Find Deal

Fri, Dec 5 - Mon, Dec 8

5:30 am - 4:51 pmPWM-DSM

12h 21m2 stops

10:55 am - 11:07 pmDSM-PWM

11h 12m2 stops

$368Delta

Find Deal

Fri, Dec 5 - Mon, Dec 8

11:50 am - 7:13 pmPWM-DSM

8h 23m1 stop

4:09 pm - 12:22 amDSM-PWM

7h 13m1 stop

$447Delta

Find Deal

Wed, Aug 13 - Sun, Aug 17

6:00 am - 1:27 pmPWM-DSM

8h 27m2 stops

4:09 pm - 12:22 amDSM-PWM

7h 13m1 stop

$452Delta

Find Deal

Wed, Aug 13 - Sun, Aug 17

6:00 am - 1:27 pmPWM-DSM

8h 27m2 stops

2:49 pm - 12:22 amDSM-PWM

8h 33m2 stops

$733Delta

Find Deal

Wed, Aug 13 - Sun, Aug 17

8:07 pm - 11:27 pmPWM-DSM

28h 20m3 stops

7:15 pm - 5:25 pmDSM-PWM

21h 10m2 stops

$739

Find Deal

Wed, Aug 13 - Sun, Aug 17

8:07 pm - 11:27 pmPWM-DSM

28h 20m3 stops

4:00 pm - 5:25 pmDSM-PWM

24h 25m3 stops

$831

Find Deal

Wed, Aug 13 - Sun, Aug 17

Delta flights from Portland, Maine to Des Moines

Our best Delta deals on Portland, Maine to Des Moines flight tickets

Delta

Dec 5

PWM4:55 pmPortland

4h 55m

1 stop

DSM8:50 pmDes Moines

Dec 8

DSM10:55 amDes Moines

11h 12m

2 stops

PWM11:07 pmPortland

$302

Find similar

Delta

Dec 5

PWM5:30 amPortland

12h 21m

2 stops

DSM4:51 pmDes Moines

Dec 8

DSM10:55 amDes Moines

11h 12m

2 stops

PWM11:07 pmPortland

$368

Find similar

Delta

Aug 13

PWM11:50 amPortland

8h 23m

1 stop

DSM7:13 pmDes Moines

Aug 17

DSM4:09 pmDes Moines

7h 13m

1 stop

PWM12:22 amPortland

$447

Find similar

American Airlines flights from Portland, Maine to Des Moines

Our best American Airlines deals on Portland, Maine to Des Moines flight tickets

American Airlines

Dec 5

PWM7:44 amPortland

5h 59m

1 stop

DSM12:43 pmDes Moines

Dec 8

DSM5:47 amDes Moines

7h 07m

1 stop

PWM1:54 pmPortland

$297

Find similar

American Airlines

Aug 2

PWM6:15 amPortland

8h 08m

1 stop

DSM1:23 pmDes Moines

Aug 3

DSM6:01 amDes Moines

5h 15m

1 stop

PWM12:16 pmPortland

$733

Find similar

American Airlines

Aug 8

PWM4:05 pmPortland

6h 40m

1 stop

DSM9:45 pmDes Moines

Aug 10

DSM5:14 pmDes Moines

5h 45m

1 stop

PWM11:59 pmPortland

$762

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Portland, Maine to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Fri 12/5

7:44 am-12:43 pm

1 stop5h 59m

Des Moines

Mon 12/8

5:47 am-1:54 pm

1 stop7h 07m

$297

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Fri 12/5

4:55 pm-8:50 pm

1 stop4h 55m

Des Moines

Mon 12/8

10:55 am-11:07 pm

2 stops11h 12m

$302

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Fri 12/5

5:30 am-4:51 pm

2 stops12h 21m

Des Moines

Mon 12/8

10:55 am-11:07 pm

2 stops11h 12m

$368

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 8/13

11:50 am-7:13 pm

1 stop8h 23m

Des Moines

Sun 8/17

4:09 pm-12:22 am

1 stop7h 13m

$447

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 8/13

6:00 am-1:27 pm

2 stops8h 27m

Des Moines

Sun 8/17

4:09 pm-12:22 am

1 stop7h 13m

$452

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 8/13

6:00 am-1:27 pm

2 stops8h 27m

Des Moines

Sun 8/17

2:49 pm-12:22 am

2 stops8h 33m

$733

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 8/13

8:07 pm-11:27 pm

3 stops28h 20m

Des Moines

Sun 8/17

7:15 pm-5:25 pm

2 stops21h 10m

$739

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 8/13

8:07 pm-11:27 pm

3 stops28h 20m

Des Moines

Sun 8/17

4:00 pm-5:25 pm

3 stops24h 25m

$831

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Sat 9/6

5:20 pm-9:58 pm

1 stop5h 38m

$149

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Sat 9/6

6:31 am-4:29 pm

2 stops10h 58m

$154

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first

How to get the cheapest flight ticket from Portland, Maine to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in August, then January is your next best option. Flight prices from Portland, Maine to Des Moines during January average around $318.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Portland, Maine to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $409. Flights from Portland, Maine to Des Moines on a Sunday will generally be more expensive and average around $778. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Portland, Maine to Des Moines in the afternoon for as low as $476. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $628. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Portland, Maine to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Portland, Maine to Des Moines (PWM to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Des Moines

Best Price Found	$149
Fastest flight time	4h 55m
Direct flights	None
Airports in Des Moines	1 airport

The best one-way flight to Des Moines from Portland, Maine in the past 72 hours is $149. The best round-trip flight deal from Portland, Maine to Des Moines found on momondo in the last 72 hours is $297.

The fastest flight from Portland, Maine to Des Moines takes 4h 55m

There are no direct flights from Portland, Maine to Des Moines. Popular non-direct route for this connection is Portland Airport - Des Moines Airport.

There is 1 airport near Des Moines: Des Moines (DSM)

Search flight deals

How far is Portland to Des Moines by plane?
Portland and Des Moines are 1192.1 mi apart from one another. Flights usually cover this in 4h 55m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Portland Airport to Des Moines Airport?
Prices for flights from Portland Airport to Des Moines Airport refresh daily.
How many operators does momondo search for flights from Portland Airport to Des Moines Airport?
There are 3 operators available for flights from Portland Airport to Des Moines Airport as of July 2025.
How old do you have to be to fly from Portland Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Portland, Maine to Des Moines?
Based on momondo bookings for flights between Portland, Maine and Des Moines, the leading airline is American Airlines, making up 47% of the total bookings. Other popular airlines include Delta with 44% and United Airlines with 9%.

Best airlines flying from Portland, Maine to Des Moines

Compare and see reviews for airlines that fly from Portland, Maine to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $229	Free Cancellation	Rating 8.0 7,981 reviews	Search Delta flights
American Airlines	PriceFrom $276	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
United Airlines	PriceFrom $328	Free Cancellation	Rating 7.4 8,900 reviews	Search United Airlines flights

West Des Moines

Ames

Ankeny

Altoona

Clive

Urbandale

Newton

Pella

Boone

Johnston

Osceola

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Des Moines?

Finding the right flight to Des Moines from Portland is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Portland to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Portland to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from Portland to Des Moines?

Once you have performed a search for Portland to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Portland to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Portland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Cheap flights from Portland, Maine to Des Moines from $149

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Des Moines departing on 9/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Find the cheapest flights from Portland, Maine to Des Moines

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Delta flights from Portland, Maine to Des Moines

Our best Delta deals on Portland, Maine to Des Moines flight tickets

American Airlines flights from Portland, Maine to Des Moines

Our best American Airlines deals on Portland, Maine to Des Moines flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Portland, Maine to Des Moines that are best for you.

See travel insights to Des Moines from

How to get the cheapest flight ticket from Portland, Maine to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in August, then January is your next best option. Flight prices from Portland, Maine to Des Moines during January average around $318.

What is the cheapest day to depart on your flight to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

What is the cheapest airline that flies from Portland to Des Moines?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Portland to Des Moines

What airlines fly to Des Moines?

Which airport is the most popular layover for flights between Portland, Maine and Des Moines?

Chicago (ORD) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Portland, Maine to Des Moines?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $431.

Which layover airport has the shortest travel time from Portland, Maine to Des Moines?

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 5h 19m.

Which layover airport has the shortest connection time from Portland, Maine to Des Moines?

Chicago (ORD) has the shortest average layover time for this route: 1h 04m.

When to book flights from Portland, Maine to Des Moines

Cheap Portland, Maine to Des Moines (PWM to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Des Moines

Best Price Found

Fastest flight time

Direct flights

Airports in Des Moines

How far is Portland to Des Moines by plane?

When did momondo last update prices for flights from Portland Airport to Des Moines Airport?

How many operators does momondo search for flights from Portland Airport to Des Moines Airport?

How old do you have to be to fly from Portland Airport to Des Moines Airport?

What documentation or ID do you need to fly to Des Moines Airport?

What is the most popular airline from Portland, Maine to Des Moines?

Best airlines flying from Portland, Maine to Des Moines

Compare and see reviews for airlines that fly from Portland, Maine to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Des Moines?

Can I find flights from Portland to Des Moines with flexible booking policies on momondo?

How can momondo help me find flights from Portland to Des Moines?

I’m not ready to book a flight from Portland to Des Moines right now. Can momondo alert me if prices change?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa