Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Portland, Maine to Des Moines from $203

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland, Maine to Des Moines departing on 5/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Portland, Maine to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:00 pm - 10:51 pm
PWM
-
DSM
6h 51m
1 stop
United Airlines Logo
6:00 am - 2:31 pm
DSM
-
PWM
7h 31m
1 stop
$371United Airlines
Tue, Jun 30 - Tue, Jul 14
United Airlines Logo
6:00 am - 2:25 pm
PWM
-
DSM
9h 25m
2 stops
United Airlines Logo
6:00 am - 2:31 pm
DSM
-
PWM
7h 31m
1 stop
$376United Airlines
Tue, Jun 30 - Tue, Jul 14
United Airlines Logo
5:15 am - 2:25 pm
PWM
-
DSM
10h 10m
2 stops
United Airlines Logo
3:24 pm - 11:51 pm
DSM
-
PWM
7h 27m
2 stops
$382United Airlines
Tue, Jun 30 - Tue, Jul 14
Delta Logo
6:00 am - 1:34 pm
PWM
-
DSM
8h 34m
1 stop
Delta Logo
2:25 pm - 11:14 pm
DSM
-
PWM
7h 49m
1 stop
$388Delta
Tue, Jul 28 - Thu, Jul 30
Delta Logo
6:00 am - 1:34 pm
PWM
-
DSM
8h 34m
1 stop
Delta Logo
2:25 pm - 12:59 am
DSM
-
PWM
9h 34m
2 stops
$393Delta
Tue, Jul 28 - Thu, Jul 30
Delta Logo
6:25 am - 1:34 pm
PWM
-
DSM
8h 09m
2 stops
Delta Logo
2:25 pm - 12:59 am
DSM
-
PWM
9h 34m
2 stops
$398Delta
Tue, Jul 28 - Thu, Jul 30
American Airlines Logo
1:25 pm - 8:51 pm
PWM
-
DSM
8h 26m
1 stop
American Airlines Logo
1:41 pm - 10:37 pm
DSM
-
PWM
7h 56m
1 stop
$399American Airlines
Wed, Jul 15 - Sun, Jul 19
Delta Logo
6:00 am - 1:34 pm
PWM
-
DSM
8h 34m
1 stop
Delta Logo
11:30 am - 12:59 am
DSM
-
PWM
12h 29m
2 stops
$404Delta
Tue, Jul 7 - Thu, Jul 9
American Airlines Logo
1:34 pm - 9:23 pm
PWM
-
DSM
8h 49m
1 stop
American Airlines Logo
4:43 pm - 11:59 pm
DSM
-
PWM
6h 16m
1 stop
$409American Airlines
Tue, Jun 2 - Fri, Jun 5
American Airlines Logo
12:19 pm - 7:32 pm
PWM
-
DSM
8h 13m
1 stop
American Airlines Logo
5:00 am - 11:03 am
DSM
-
PWM
5h 03m
1 stop
$416American Airlines
Sun, May 24 - Sat, May 30

Delta flights from Portland, Maine to Des Moines

Our best Delta deals on Portland, Maine to Des Moines flight tickets
Delta
Jul 28
PWM6:00 amPortland
8h 34m
1 stop
DSM1:34 pmDes Moines
Jul 30
DSM2:25 pmDes Moines
7h 49m
1 stop
PWM11:14 pmPortland
$388
Delta
Jul 28
PWM6:00 amPortland
8h 34m
1 stop
DSM1:34 pmDes Moines
Jul 30
DSM2:25 pmDes Moines
9h 34m
2 stops
PWM12:59 amPortland
$393
Delta
Jul 28
PWM6:25 amPortland
8h 09m
2 stops
DSM1:34 pmDes Moines
Jul 30
DSM2:25 pmDes Moines
9h 34m
2 stops
PWM12:59 amPortland
$398

American Airlines flights from Portland, Maine to Des Moines

Our best American Airlines deals on Portland, Maine to Des Moines flight tickets
American Airlines
Jul 15
PWM1:25 pmPortland
8h 26m
1 stop
DSM8:51 pmDes Moines
Jul 19
DSM1:41 pmDes Moines
7h 56m
1 stop
PWM10:37 pmPortland
$399
American Airlines
Jun 2
PWM1:34 pmPortland
8h 49m
1 stop
DSM9:23 pmDes Moines
Jun 5
DSM4:43 pmDes Moines
6h 16m
1 stop
PWM11:59 pmPortland
$409
American Airlines
May 24
PWM12:19 pmPortland
8h 13m
1 stop
DSM7:32 pmDes Moines
May 30
DSM5:00 amDes Moines
5h 03m
1 stop
PWM11:03 amPortland
$416

momondo Fare Finder

 
Customize your flight search to find flights from Portland, Maine to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from Portland, Maine to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 6/30

5:00 pm-10:51 pm

1 stop6h 51m

Des Moines

Tue 7/14

6:00 am-2:31 pm

1 stop7h 31m

$371

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 6/30

6:00 am-2:25 pm

2 stops9h 25m

Des Moines

Tue 7/14

6:00 am-2:31 pm

1 stop7h 31m

$376

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 6/30

5:15 am-2:25 pm

2 stops10h 10m

Des Moines

Tue 7/14

3:24 pm-11:51 pm

2 stops7h 27m

$382

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 7/28

6:00 am-1:34 pm

1 stop8h 34m

Des Moines

Thu 7/30

2:25 pm-11:14 pm

1 stop7h 49m

$388

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 7/28

6:00 am-1:34 pm

1 stop8h 34m

Des Moines

Thu 7/30

2:25 pm-12:59 am

2 stops9h 34m

$393

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 7/28

6:25 am-1:34 pm

2 stops8h 09m

Des Moines

Thu 7/30

2:25 pm-12:59 am

2 stops9h 34m

$398

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Wed 7/15

1:25 pm-8:51 pm

1 stop8h 26m

Des Moines

Sun 7/19

1:41 pm-10:37 pm

1 stop7h 56m

$399

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 7/7

6:00 am-1:34 pm

1 stop8h 34m

Des Moines

Thu 7/9

11:30 am-12:59 am

2 stops12h 29m

$404

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Tue 6/2

1:34 pm-9:23 pm

1 stop8h 49m

Des Moines

Fri 6/5

4:43 pm-11:59 pm

1 stop6h 16m

$409
Quickest round-trip

PortlandDes Moines

PWM - DSM

PWMDSM

Portland

Sun 5/24

12:19 pm-7:32 pm

1 stop8h 13m

Des Moines

Sat 5/30

5:00 am-11:03 am

1 stop5h 03m

$416

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Portland, Maine to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Portland, Maine and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in April, then February is your next best option. Flight prices from Portland, Maine to Des Moines during February average around $0.

When to book flights from Portland, Maine to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Portland, Maine to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland, Maine to Des Moines (PWM to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland, Maine to Des Moines

Fastest flight time

4h 58m

Direct flights

None
The fastest flight from Portland, Maine to Des Moines takes 4h 58m
There are no direct flights from Portland, Maine to Des Moines. There are no popular flight routes from Portland, Maine to Des Moines.
Search flight deals

Frequently asked questions about flying from Portland, Maine to Des Moines

  • How far is Portland to Des Moines by plane?

    Portland and Des Moines are 1192.1 mi apart from one another. Flights usually cover this in 4h 58m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Portland Airport to Des Moines Airport?

    Prices for flights from Portland Airport to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from Portland Airport to Des Moines Airport?

  • How old do you have to be to fly from Portland Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Portland, Maine to Des Moines?

Best airlines flying from Portland, Maine to Des Moines

Compare and see reviews for airlines that fly from Portland, Maine to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $193Free CancellationRating
7.9
8,446 reviews
Search Delta flights
American AirlinesPriceFrom $249Free CancellationRating
7.1
11,661 reviews
Search American Airlines flights
United AirlinesPriceFrom $328Free CancellationRating
7.4
9,701 reviews
Search United Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Des Moines?

Finding the right flight to Des Moines from Portland is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Portland to Des Moines with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Portland to Des Moines flights to just show those with flexible booking policies.

How can momondo help me find flights from Portland to Des Moines?

Once you have performed a search for Portland to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Portland to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Portland are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 6/11
Thu 6/18
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States