Which airport is the most popular layover for flights between Pittsburgh and Des Moines?

Chicago (MDW) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Pittsburgh to Des Moines?

Flights via Detroit (DTW) offer the lowest average round-trip price of $386.

What airlines fly to Des Moines?

United Airlines, Delta and American Airlines are the top three most popular airlines that fly to Des Moines from Pittsburgh according to our data. United Airlines is the first choice among our users, with 30% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 4 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from Pittsburgh to Des Moines?

Flights connecting via Detroit (DTW) have the shortest average one-way travel time: 3h 55m.

What is the cheapest airline that flies from Pittsburgh to Des Moines?

American Airlines, Delta, and Southwest are the most popular carriers operating from Pittsburgh to Des Moines

Which layover airport has the shortest connection time from Pittsburgh to Des Moines?

Detroit (DTW) has the shortest average layover time for this route: 0h 57m.

When did momondo last update prices for flights from Pittsburgh Airport to Des Moines Airport?

Prices for flights from Pittsburgh Airport to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Pittsburgh Airport to Des Moines Airport?

As of September 2026, there are 4 operators available to choose from for flights from Pittsburgh Airport to Des Moines Airport.

How old do you have to be to fly from Pittsburgh Airport to Des Moines Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Pittsburgh Airport to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$155 Cheap Flights from Pittsburgh to Des Moines in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Pittsburgh to Des Moines

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:00 pm - 9:23 pmPIT Pittsburgh-DSM Des Moines

4h 23m1 stop Chicago O'Hare Intl

6:45 pm - 11:59 pmDSM Des Moines-PIT Pittsburgh

4h 14m1 stop Chicago O'Hare Intl

$332United Airlines

Fri, Oct 23 - Mon, Oct 26

7:45 pm - 11:15 pmPIT Pittsburgh-DSM Des Moines

4h 30m1 stop Chicago Midway

5:10 am - 12:55 pmDSM Des Moines-PIT Pittsburgh

6h 45m2 stops Chicago Midway Lambert-St Louis

$360Southwest

Fri, Oct 23 - Mon, Oct 26

7:00 am - 10:31 amPIT Pittsburgh-DSM Des Moines

4h 31m1 stop Chicago O'Hare Intl

6:55 pm - 11:59 pmDSM Des Moines-PIT Pittsburgh

4h 04m1 stop Chicago O'Hare Intl

$389United Airlines

Thu, Oct 1 - Mon, Oct 5

1:40 pm - 10:10 pmPIT Pittsburgh-DSM Des Moines

9h 30m2 stops Chicago Midway Denver Intl

5:10 am - 12:55 pmDSM Des Moines-PIT Pittsburgh

6h 45m2 stops Chicago Midway Lambert-St Louis

$397Southwest

Fri, Oct 23 - Mon, Oct 26

1:25 pm - 10:08 pmPIT Pittsburgh-DSM Des Moines

9h 43m1 stop Fort Myers SW Florida Intl

9:39 am - 10:53 pmDSM Des Moines-PIT Pittsburgh

12h 14m1 stop Nashville Intl

$417Multiple Airlines

Fri, Sep 25 - Sun, Sep 27

6:30 am - 2:15 pmPIT Pittsburgh-DSM Des Moines

8h 45m2 stops Newark Chicago O'Hare Intl

6:55 pm - 11:59 pmDSM Des Moines-PIT Pittsburgh

4h 04m1 stop Chicago O'Hare Intl

$417United Airlines

Thu, Oct 1 - Mon, Oct 5

1:25 pm - 10:08 pmPIT Pittsburgh-DSM Des Moines

9h 43m1 stop Fort Myers SW Florida Intl

1:58 pm - 7:59 pmDSM Des Moines-PIT Pittsburgh

29h 01m2 stops Philadelphia Raleigh-Durham

$427Multiple Airlines

Fri, Sep 25 - Sun, Sep 27

1:04 pm - 7:09 pmPIT Pittsburgh-DSM Des Moines

7h 05m1 stop Chicago O'Hare Intl

3:26 pm - 8:59 pmDSM Des Moines-PIT Pittsburgh

4h 33m1 stop Chicago O'Hare Intl

$444American Airlines

Wed, Dec 30 - Sun, Jan 3

5:25 am - 11:15 amPIT Pittsburgh-DSM Des Moines

6h 50m2 stops Baltimore/Washington Chicago Midway

5:10 am - 10:00 amDSM Des Moines-PIT Pittsburgh

3h 50m1 stop Chicago Midway

$472Southwest

Wed, Dec 30 - Sun, Jan 3

5:16 pm - 9:36 pmPIT Pittsburgh-DSM Des Moines

5h 20m1 stop Philadelphia

7:12 am - 2:33 pmDSM Des Moines-PIT Pittsburgh

6h 21m1 stop New York LaGuardia

$477American Airlines

Thu, Oct 1 - Thu, Oct 8

Cheap last minute flights

Enter your travel dates to find the best prices.

5:47 pm - 5:09 pmPIT Pittsburgh-DSM Des Moines

24h 22m1 stop Fort Myers SW Florida Intl

12:44 pm - 12:38 pmDSM Des Moines-PIT Pittsburgh

22h 54m1 stop Orlando Sanford Intl

$531Multiple Airlines

Sun, Sep 13 - Wed, Sep 16

5:47 pm - 5:09 pmPIT Pittsburgh-DSM Des Moines

24h 22m1 stop Fort Myers SW Florida Intl

12:44 pm - 11:45 amDSM Des Moines-PIT Pittsburgh

46h 01m2 stops Orlando Sanford Intl Louisville Intl

$589Multiple Airlines

Sun, Sep 13 - Wed, Sep 16

5:16 pm - 9:36 pmPIT Pittsburgh-DSM Des Moines

5h 20m1 stop Philadelphia

7:05 am - 3:13 pmDSM Des Moines-PIT Pittsburgh

7h 08m1 stop Chicago O'Hare Intl

$635American Airlines

Thu, Sep 10 - Sat, Sep 12

8:05 am - 3:15 pmPIT Pittsburgh-DSM Des Moines

8h 10m2 stops Chicago Midway Denver Intl

6:10 am - 1:05 pmDSM Des Moines-PIT Pittsburgh

5h 55m2 stops Chicago Midway Lambert-St Louis

$638Southwest

Sun, Sep 13 - Wed, Sep 16

6:10 am - 1:45 pmPIT Pittsburgh-DSM Des Moines

8h 35m2 stops Nashville Intl Denver Intl

12:10 pm - 5:35 pmDSM Des Moines-PIT Pittsburgh

4h 25m1 stop Chicago Midway

$640Southwest

Thu, Sep 10 - Sat, Sep 12

7:30 pm - 10:15 pmPIT Pittsburgh-DSM Des Moines

3h 45m1 stop Chicago Midway

2:25 pm - 11:15 pmDSM Des Moines-PIT Pittsburgh

7h 50m1 stop Denver Intl

$674Southwest

Mon, Sep 14 - Fri, Sep 18

1:50 pm - 10:15 pmPIT Pittsburgh-DSM Des Moines

9h 25m2 stops Atlanta Hartsfield-Jackson Chicago Midway

12:10 pm - 8:50 pmDSM Des Moines-PIT Pittsburgh

7h 40m2 stops Chicago Midway Baltimore/Washington

$675Southwest

Thu, Sep 10 - Sat, Sep 12

6:10 pm - 9:28 pmPIT Pittsburgh-DSM Des Moines

4h 18m1 stop Chicago O'Hare Intl

6:15 am - 7:09 pmDSM Des Moines-PIT Pittsburgh

11h 54m2 stops Houston George Bush Intcntl Newark

$689United Airlines

Mon, Sep 14 - Fri, Sep 18

6:10 pm - 9:28 pmPIT Pittsburgh-DSM Des Moines

4h 18m1 stop Chicago O'Hare Intl

8:00 am - 10:30 pmDSM Des Moines-PIT Pittsburgh

13h 30m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Newark

$694United Airlines

Mon, Sep 14 - Fri, Sep 18

6:10 am - 2:20 pmPIT Pittsburgh-DSM Des Moines

9h 10m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl

8:00 am - 8:36 pmDSM Des Moines-PIT Pittsburgh

11h 36m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Newark

$951United Airlines

Thu, Sep 10 - Sat, Sep 12

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United Airlines flights from Pittsburgh to Des Moines

Our best United Airlines deals on Pittsburgh to Des Moines flight tickets

United Airlines

Oct 23

PIT6:00 pmPittsburgh

4h 23m

1 stop

DSM9:23 pmDes Moines

Oct 26

DSM6:45 pmDes Moines

4h 14m

1 stop

PIT11:59 pmPittsburgh

$332

United Airlines

Oct 9

PIT7:00 amPittsburgh

4h 31m

1 stop

DSM10:31 amDes Moines

Oct 16

DSM3:11 pmDes Moines

4h 25m

1 stop

PIT8:36 pmPittsburgh

$355

United Airlines

Oct 1

PIT7:00 amPittsburgh

4h 31m

1 stop

DSM10:31 amDes Moines

Oct 5

DSM6:55 pmDes Moines

4h 04m

1 stop

PIT11:59 pmPittsburgh

$389

American Airlines flights from Pittsburgh to Des Moines

Our best American Airlines deals on Pittsburgh to Des Moines flight tickets

American Airlines

Dec 30

PIT1:04 pmPittsburgh

7h 05m

1 stop

DSM7:09 pmDes Moines

Jan 3

DSM3:26 pmDes Moines

4h 33m

1 stop

PIT8:59 pmPittsburgh

$444

American Airlines

Oct 4

PIT6:29 pmPittsburgh

6h 12m

1 stop

DSM11:41 pmDes Moines

Oct 11

DSM6:02 amDes Moines

6h 55m

1 stop

PIT1:57 pmPittsburgh

$632

American Airlines

Sep 10

PIT5:16 pmPittsburgh

5h 20m

1 stop

DSM9:36 pmDes Moines

Sep 12

DSM7:05 amDes Moines

7h 08m

1 stop

PIT3:13 pmPittsburgh

$635

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PittsburghDes Moines

PIT Pittsburgh - DSM Des Moines

PITDSM

Pittsburgh

Fri 10/23

6:00 pm-9:23 pm

1 stop4h 23m

Des Moines

Mon 10/26

6:45 pm-11:59 pm

1 stop4h 14m

$332

PittsburghDes Moines

PIT Pittsburgh - DSM Des Moines

PITDSM

Pittsburgh

Fri 10/23

7:45 pm-11:15 pm

1 stop4h 30m

Des Moines

Mon 10/26

5:10 am-12:55 pm

2 stops6h 45m

$360

Quickest round-trip

PittsburghDes Moines

PIT Pittsburgh - DSM Des Moines

PITDSM

Pittsburgh

Thu 10/1

7:00 am-10:31 am

1 stop4h 31m

Des Moines

Mon 10/5

6:55 pm-11:59 pm

1 stop4h 04m

$389

PittsburghDes Moines

PIT Pittsburgh - DSM Des Moines

PITDSM

Pittsburgh

Fri 10/23

1:40 pm-10:10 pm

2 stops9h 30m

Des Moines

Mon 10/26

5:10 am-12:55 pm

2 stops6h 45m

$397

PittsburghDes Moines

PIT Pittsburgh - DSM Des Moines

PITDSM

Pittsburgh

Fri 9/25

1:25 pm-10:08 pm

1 stop9h 43m

Des Moines

Sun 9/27

9:39 am-10:53 pm

1 stop12h 14m

$417

PittsburghDes Moines

PIT Pittsburgh - DSM Des Moines

PITDSM

Pittsburgh

Thu 10/1

6:30 am-2:15 pm

2 stops8h 45m

Des Moines

Mon 10/5

6:55 pm-11:59 pm

1 stop4h 04m

$417

PittsburghDes Moines

PIT Pittsburgh - DSM Des Moines

PITDSM

Pittsburgh

Fri 9/25

1:25 pm-10:08 pm

1 stop9h 43m

Des Moines

Sun 9/27

1:58 pm-7:59 pm

2 stops29h 01m

$427

PittsburghDes Moines

PIT Pittsburgh - DSM Des Moines

PITDSM

Pittsburgh

Wed 12/30

1:04 pm-7:09 pm

1 stop7h 05m

Des Moines

Sun 1/3

3:26 pm-8:59 pm

1 stop4h 33m

$444

PittsburghDes Moines

PIT Pittsburgh - DSM Des Moines

PITDSM

Pittsburgh

Wed 12/30

5:25 am-11:15 am

2 stops6h 50m

Des Moines

Sun 1/3

5:10 am-10:00 am

1 stop3h 50m

$472

PittsburghDes Moines

PIT Pittsburgh - DSM Des Moines

PITDSM

Pittsburgh

Thu 10/1

5:16 pm-9:36 pm

1 stop5h 20m

Des Moines

Thu 10/8

7:12 am-2:33 pm

1 stop6h 21m

$477

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Pittsburgh to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between Pittsburgh and Des Moines?

Prices are currently low for flights on this route.

Typical prices usually range from $367 to $572.
The lowest price recently found on this route was $332.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in October, then November is your next best option. Flight prices from Pittsburgh to Des Moines during November average around $311.

Can stopping save me money on Pittsburgh to Des Moines flights?

You could potentially save up to 18% on your flight if you consider stops on a Pittsburgh to Des Moines flight.

How have Pittsburgh to Des Moines flight prices changed over time?

When to book flights from Pittsburgh to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Pittsburgh to Des Moines according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Pittsburgh to Des Moines (PIT to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pittsburgh to Des Moines

Best Price Found	$155
Fastest flight time	4h 31m
Direct flights	None

The best one-way flight to Des Moines from Pittsburgh in the past 72 hours is $155. The best round-trip flight deal from Pittsburgh to Des Moines found on momondo in the last 72 hours is $332.

The fastest flight from Pittsburgh to Des Moines takes 4h 31m

There are no direct flights from Pittsburgh to Des Moines. There are no popular flight routes from Pittsburgh to Des Moines.

Search flight deals

Frequently asked questions about flying from Pittsburgh to Des Moines

How far is Pittsburgh to Des Moines by plane?
The straight-line distance from Pittsburgh to Des Moines is 713.9 mi. Flights usually cover this in 4h 31m, depending on flying conditions and air traffic around both airports.
When did momondo last update prices for flights from Pittsburgh Airport to Des Moines Airport?
Prices for flights from Pittsburgh Airport to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Pittsburgh Airport to Des Moines Airport?
As of September 2026, there are 4 operators available to choose from for flights from Pittsburgh Airport to Des Moines Airport.
How old do you have to be to fly from Pittsburgh Airport to Des Moines Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Pittsburgh Airport to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Pittsburgh to Des Moines?
momondo data reveals that the most frequently booked airline on the route from Pittsburgh to Des Moines is United Airlines, representing 30% of all bookings. The subsequent popular airlines are Delta at 30%, American Airlines at 21%, and Southwest at 19%.

Best airlines flying from Pittsburgh to Des Moines

Compare and see reviews for airlines that fly from Pittsburgh to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $256	Free Cancellation	Rating 7.1 12,045 reviews	Search American Airlines flights
Delta	PriceFrom $281	Free Cancellation	Rating 7.8 8,554 reviews	Search Delta flights
United Airlines	PriceFrom $296	Free Cancellation	Rating 7.4 10,194 reviews	Search United Airlines flights
Southwest	PriceFrom $316	Free Cancellation	Rating 8.0 4,195 reviews	Search Southwest flights

West Des Moines

Ames

Ankeny

Clive

Altoona

Pella

Osceola

Urbandale

Newton

Johnston

Boone

Oskaloosa

Grinnell

Norwalk

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Pittsburgh to Des Moines?

Finding the right flight to Des Moines from Pittsburgh is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Pittsburgh to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Pittsburgh on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Pittsburgh to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Pittsburgh. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Pittsburgh to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Pittsburgh to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Pittsburgh to Des Moines from $155

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pittsburgh to Des Moines departing on 10/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Pittsburgh to Des Moines

Our best United Airlines deals on Pittsburgh to Des Moines flight tickets

American Airlines flights from Pittsburgh to Des Moines

Our best American Airlines deals on Pittsburgh to Des Moines flight tickets

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See travel insights to Des Moines from

How to get the cheapest flight ticket from Pittsburgh to Des Moines

What is the typical price of a round-trip flight between Pittsburgh and Des Moines?

What is the cheapest month to fly to Des Moines?

Can stopping save me money on Pittsburgh to Des Moines flights?

How have Pittsburgh to Des Moines flight prices changed over time?

What is the cheapest airline that flies from Pittsburgh to Des Moines?

What airlines fly to Des Moines?

Which airport is the most popular layover for flights between Pittsburgh and Des Moines?

Which layover airport offers the lowest fares from Pittsburgh to Des Moines?

Which layover airport has the shortest travel time from Pittsburgh to Des Moines?

Which layover airport has the shortest connection time from Pittsburgh to Des Moines?

When to book flights from Pittsburgh to Des Moines

Cheap Pittsburgh to Des Moines (PIT to DSM) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Pittsburgh to Des Moines

Best airlines flying from Pittsburgh to Des Moines

Compare and see reviews for airlines that fly from Pittsburgh to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa

Fly your favorite airline to Des Moines

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Des Moines

List of cabin classes available on flights landing in Des Moines. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

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