Cheap flights from Pennsylvania to South America from $147

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Pennsylvania to South America departing on 11/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Pennsylvania to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
1:00 am - 5:25 am
JFK
-
MDE
5h 25mnonstop
Avianca Logo
2:10 pm - 2:05 am
MDE
-
JFK
10h 55m
1 stop
$389Avianca
Mon, Aug 17 - Sun, Aug 23
Copa Airlines Logo
2:20 am - 9:40 am
JFK
-
MDE
8h 20m
1 stop
Copa Airlines Logo
6:20 pm - 3:59 am
MDE
-
JFK
8h 39m
1 stop
$393Copa Airlines
Mon, Sep 21 - Fri, Sep 25
United Airlines Logo
12:00 pm - 9:10 pm
EWR
-
MDE
10h 10m
1 stop
United Airlines Logo
9:45 am - 9:28 pm
MDE
-
EWR
10h 43m
1 stop
$393United Airlines
Sun, Sep 6 - Sun, Oct 11
Arajet Logo
12:59 am - 9:20 am
EWR
-
MDE
9h 21m
1 stop
Arajet Logo
7:00 pm - 10:30 am
MDE
-
EWR
14h 30m
1 stop
$394Arajet
Mon, Sep 21 - Sun, Oct 4
Arajet Logo
12:00 pm - 7:40 pm
EWR
-
MDE
8h 40m
1 stop
Arajet Logo
7:00 pm - 10:30 am
MDE
-
EWR
14h 30m
1 stop
$400Arajet
Wed, Sep 23 - Sun, Oct 4
United Airlines Logo
6:00 am - 9:10 pm
EWR
-
MDE
16h 10m
1 stop
United Airlines Logo
9:45 am - 10:44 pm
MDE
-
EWR
11h 59m
1 stop
$403United Airlines
Fri, Sep 25 - Sun, Oct 11
Multiple Airlines Logo
6:00 am - 9:10 pm
LGA
-
MDE
16h 10m
1 stop
Multiple Airlines Logo
9:45 am - 8:59 pm
MDE
-
LGA
10h 14m
1 stop
$409Multiple Airlines
Sat, Sep 5 - Sun, Sep 13
Multiple Airlines Logo
6:00 am - 9:10 pm
EWR
-
MDE
16h 10m
1 stop
Multiple Airlines Logo
9:45 am - 12:49 am
MDE
-
EWR
14h 04m
1 stop
$409Multiple Airlines
Wed, Aug 26 - Tue, Sep 1
American Airlines Logo
7:25 am - 8:15 pm
JFK
-
MDE
13h 50m
1 stop
American Airlines Logo
6:00 am - 9:30 pm
MDE
-
JFK
14h 30m
1 stop
$410American Airlines
Tue, Sep 15 - Sun, Sep 27
American Airlines Logo
6:59 am - 7:55 pm
LGA
-
MDE
13h 56m
1 stop
American Airlines Logo
7:00 am - 8:00 pm
MDE
-
LGA
13h 00m
1 stop
$410American Airlines
Sat, Oct 31 - Sat, Nov 7

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LATAM Airlines flights from Pennsylvania to South America

Our best LATAM Airlines deals on Pennsylvania to South America flight tickets
LATAM Airlines
Nov 11
JFK8:35 amNew York John F Kennedy Intl
10h 55m
1 stop
BOG7:30 pmBogotá El Dorado
Nov 12
BOG10:00 amBogotá El Dorado
13h 40m
2 stops
JFK11:40 pmNew York John F Kennedy Intl
$413
LATAM Airlines
Jun 20
JFK8:40 amNew York John F Kennedy Intl
24h 00m
2 stops
MDE7:40 amMedellín Jose Maria Cordova Intl
Jun 27
MDE10:00 amMedellín Jose Maria Cordova Intl
23h 00m
2 stops
JFK10:00 amNew York John F Kennedy Intl
$433
LATAM Airlines
Sep 5
JFK1:29 amNew York John F Kennedy Intl
6h 45m
GYE7:14 amGuayaquil Jose Joaquin de Olmedo
Oct 18
GYE4:19 pmGuayaquil Jose Joaquin de Olmedo
6h 40m
JFK11:59 pmNew York John F Kennedy Intl
$445

Avianca flights from Pennsylvania to South America

Our best Avianca deals on Pennsylvania to South America flight tickets
Avianca
Aug 17
JFK1:00 amNew York John F Kennedy Intl
5h 25m
MDE5:25 amMedellín Jose Maria Cordova Intl
Aug 23
MDE2:10 pmMedellín Jose Maria Cordova Intl
10h 55m
1 stop
JFK2:05 amNew York John F Kennedy Intl
$389
Avianca
Aug 17
JFK1:00 amNew York John F Kennedy Intl
5h 25m
MDE5:25 amMedellín Jose Maria Cordova Intl
Aug 25
MDE9:50 pmMedellín Jose Maria Cordova Intl
29h 25m
1 stop
JFK4:15 amNew York John F Kennedy Intl
$396
Avianca
Aug 20
JFK5:40 amNew York John F Kennedy Intl
16h 50m
1 stop
MDE9:30 pmMedellín Jose Maria Cordova Intl
Aug 23
MDE2:10 pmMedellín Jose Maria Cordova Intl
10h 55m
1 stop
JFK2:05 amNew York John F Kennedy Intl
$398

momondo Fare Finder

 
Customize your flight search to find flights from Pennsylvania to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Pennsylvania to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

New YorkMedellín

JFK - MDE

JFKMDE

New York John F Kennedy Intl

Mon 8/17

1:00 am-5:25 am

Nonstop5h 25m

Medellín Jose Maria Cordova Intl

Sun 8/23

2:10 pm-2:05 am

1 stop10h 55m

$389

New YorkMedellín

JFK - MDE

JFKMDE

New York John F Kennedy Intl

Mon 9/21

2:20 am-9:40 am

1 stop8h 20m

Medellín Jose Maria Cordova Intl

Fri 9/25

6:20 pm-3:59 am

1 stop8h 39m

$393

NewarkMedellín

EWR - MDE

EWRMDE

Newark

Sun 9/6

12:00 pm-9:10 pm

1 stop10h 10m

Medellín Jose Maria Cordova Intl

Sun 10/11

9:45 am-9:28 pm

1 stop10h 43m

$393

NewarkMedellín

EWR - MDE

EWRMDE

Newark

Mon 9/21

12:59 am-9:20 am

1 stop9h 21m

Medellín Jose Maria Cordova Intl

Sun 10/4

7:00 pm-10:30 am

1 stop14h 30m

$394

NewarkMedellín

EWR - MDE

EWRMDE

Newark

Wed 9/23

12:00 pm-7:40 pm

1 stop8h 40m

Medellín Jose Maria Cordova Intl

Sun 10/4

7:00 pm-10:30 am

1 stop14h 30m

$400

NewarkMedellín

EWR - MDE

EWRMDE

Newark

Fri 9/25

6:00 am-9:10 pm

1 stop16h 10m

Medellín Jose Maria Cordova Intl

Sun 10/11

9:45 am-10:44 pm

1 stop11h 59m

$403

New YorkMedellín

LGA - MDE

LGAMDE

New York LaGuardia

Sat 9/5

6:00 am-9:10 pm

1 stop16h 10m

Medellín Jose Maria Cordova Intl

Sun 9/13

9:45 am-8:59 pm

1 stop10h 14m

$409

NewarkMedellín

EWR - MDE

EWRMDE

Newark

Wed 8/26

6:00 am-9:10 pm

1 stop16h 10m

Medellín Jose Maria Cordova Intl

Tue 9/1

9:45 am-12:49 am

1 stop14h 04m

$409

New YorkMedellín

JFK - MDE

JFKMDE

New York John F Kennedy Intl

Tue 9/15

7:25 am-8:15 pm

1 stop13h 50m

Medellín Jose Maria Cordova Intl

Sun 9/27

6:00 am-9:30 pm

1 stop14h 30m

$410

New YorkMedellín

LGA - MDE

LGAMDE

New York LaGuardia

Sat 10/31

6:59 am-7:55 pm

1 stop13h 56m

Medellín Jose Maria Cordova Intl

Sat 11/7

7:00 am-8:00 pm

1 stop13h 00m

$410

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Pennsylvania to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, April is the cheapest month to fly from Pennsylvania to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $82. If you aren’t able to travel during the month of April, then book flights to South America from Pennsylvania during June instead. Flights to South America in June, while not as cheap as those in April, still average around $86.

How far in advance should I book a flight from Pennsylvania to South America?

You are more likely to see cheaper flights to South America from Pennsylvania when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $833 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Pennsylvania for as low as $686 on momondo.

Cheap Pennsylvania to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Pennsylvania to South America

Fastest flight time

5h 03m

Direct flights

Every day

Airports in South America

464 airports
The fastest flight from Pennsylvania to South America takes 5h 03m
Direct flights go from Pennsylvania to South America every day.
There are 464 airports in South America. From Pennsylvania there are direct flights to Cartagena Rafael Nunez (CTG).

Frequently asked questions about flying from Pennsylvania to South America

  • When did momondo last update prices for flights from Pennsylvania to South America?

    Prices for flights from Pennsylvania to South America refresh daily.

  • How many operators does momondo search for flights from Pennsylvania to South America?

  • How old do you have to be to fly from Pennsylvania to South America?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Pennsylvania to South America.

  • What documentation or ID do you need to fly to South America?

    The travel and health documents required for your trip to South America can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South America. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Pennsylvania to South America

Compare and see reviews for airlines that fly from Pennsylvania to South America with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $297Free CancellationRating
7.1
2,982 reviews
Search JetBlue flights
United AirlinesPriceFrom $355Free CancellationRating
7.4
9,813 reviews
Search United Airlines flights
American AirlinesPriceFrom $382Free CancellationRating
7.1
11,650 reviews
Search American Airlines flights
DeltaPriceFrom $404Free CancellationRating
7.9
8,404 reviews
Search Delta flights
LATAM AirlinesPriceFrom $478Free CancellationRating
7.4
1,931 reviews
Search LATAM Airlines flights
Air CanadaPriceFrom $493Free CancellationRating
7.1
11,172 reviews
Search Air Canada flights
GOLPriceFrom $560Free CancellationRating
7.3
1,228 reviews
Search GOL flights
Copa AirlinesPriceFrom $617Free CancellationRating
7.5
1,569 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Pennsylvania to South America?

Finding the right flight to South America from Pennsylvania is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Pennsylvania to South America with flexible booking policies on momondo?

Flights from Pennsylvania to South America with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Pennsylvania to South America?

momondo provides multiple filters to help you find the best flight to South America from Pennsylvania. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Pennsylvania to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Pennsylvania. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

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1 adult
Sun 7/12
Sun 7/19

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