Latest deals
Insights
FAQs
Price Alerts

Cheap flights from Panama to Charleston from $399

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Charleston departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama to Charleston

Recent round-trip flight deals from Panama to Charleston

Enter your travel dates to find the best prices.
United Airlines Logo
7:55 am - 10:12 pm
PTY
-
CHS
13h 17m
1 stop
United Airlines Logo
11:03 am - 7:31 pm
CHS
-
PTY
9h 28m
1 stop
$399United Airlines
Wed, May 27 - Wed, Jun 3
United Airlines Logo
10:00 am - 10:12 pm
PTY
-
CHS
11h 12m
1 stop
United Airlines Logo
11:03 am - 7:31 pm
CHS
-
PTY
9h 28m
1 stop
$410United Airlines
Wed, May 27 - Wed, Jun 3
American Airlines Logo
1:14 pm - 10:07 am
PTY
-
CHS
19h 53m
2 stops
American Airlines Logo
6:18 pm - 12:14 pm
CHS
-
PTY
18h 56m
2 stops
$420American Airlines
Wed, May 27 - Wed, Jun 3
American Airlines Logo
1:14 pm - 11:55 pm
PTY
-
CHS
9h 41m
1 stop
American Airlines Logo
1:00 pm - 12:14 pm
CHS
-
PTY
24h 14m
2 stops
$432American Airlines
Wed, May 27 - Wed, Jun 3
American Airlines Logo
1:14 pm - 10:07 am
PTY
-
CHS
19h 53m
2 stops
American Airlines Logo
6:09 pm - 12:14 pm
CHS
-
PTY
19h 05m
2 stops
$433American Airlines
Wed, May 27 - Wed, Jun 3
American Airlines Logo
1:14 pm - 11:01 am
PTY
-
CHS
20h 47m
2 stops
American Airlines Logo
6:18 pm - 12:14 pm
CHS
-
PTY
18h 56m
2 stops
$439American Airlines
Mon, Jun 1 - Tue, Jun 16
American Airlines Logo
1:14 pm - 11:55 pm
PTY
-
CHS
9h 41m
1 stop
American Airlines Logo
6:09 pm - 12:14 pm
CHS
-
PTY
19h 05m
2 stops
$450American Airlines
Wed, May 27 - Wed, Jun 3
American Airlines Logo
1:14 pm - 1:07 pm
PTY
-
CHS
22h 53m
2 stops
American Airlines Logo
6:18 pm - 12:14 pm
CHS
-
PTY
18h 56m
2 stops
$452American Airlines
Mon, Jun 1 - Tue, Jun 16
American Airlines Logo
1:14 pm - 11:55 pm
PTY
-
CHS
9h 41m
1 stop
American Airlines Logo
3:12 pm - 12:14 pm
CHS
-
PTY
22h 02m
2 stops
$461American Airlines
Mon, Jun 1 - Tue, Jun 16
American Airlines Logo
1:14 pm - 11:55 pm
PTY
-
CHS
9h 41m
1 stop
American Airlines Logo
3:12 pm - 12:14 pm
CHS
-
PTY
22h 02m
2 stops
$469American Airlines
Mon, Jun 1 - Tue, Jun 16

United Airlines flights from Panama to Charleston

Our best United Airlines deals on Panama to Charleston flight tickets
United Airlines
May 27
PTY7:55 amPanama City Tocumen Intl
13h 17m
1 stop
CHS10:12 pmCharleston
Jun 3
CHS11:03 amCharleston
9h 28m
1 stop
PTY7:31 pmPanama City Tocumen Intl
$399
United Airlines
May 27
PTY10:00 amPanama City Tocumen Intl
11h 12m
1 stop
CHS10:12 pmCharleston
Jun 3
CHS11:03 amCharleston
9h 28m
1 stop
PTY7:31 pmPanama City Tocumen Intl
$410
United Airlines
Feb 19
PTY8:55 amPanama City Tocumen Intl
13h 03m
1 stop
CHS9:58 pmCharleston
Feb 24
CHS6:35 amCharleston
13h 03m
1 stop
PTY7:38 pmPanama City Tocumen Intl
$572

American Airlines flights from Panama to Charleston

Our best American Airlines deals on Panama to Charleston flight tickets
American Airlines
May 27
PTY1:14 pmPanama City Tocumen Intl
19h 53m
2 stops
CHS10:07 amCharleston
Jun 3
CHS6:18 pmCharleston
18h 56m
2 stops
PTY12:14 pmPanama City Tocumen Intl
$420
American Airlines
May 27
PTY1:14 pmPanama City Tocumen Intl
9h 41m
1 stop
CHS11:55 pmCharleston
Jun 3
CHS1:00 pmCharleston
24h 14m
2 stops
PTY12:14 pmPanama City Tocumen Intl
$432
American Airlines
May 27
PTY1:14 pmPanama City Tocumen Intl
19h 53m
2 stops
CHS10:07 amCharleston
Jun 3
CHS6:09 pmCharleston
19h 05m
2 stops
PTY12:14 pmPanama City Tocumen Intl
$433

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Panama to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

7:55 am-10:12 pm

1 stop13h 17m

Charleston

Wed 6/3

11:03 am-7:31 pm

1 stop9h 28m

$399

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

10:00 am-10:12 pm

1 stop11h 12m

Charleston

Wed 6/3

11:03 am-7:31 pm

1 stop9h 28m

$410

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

1:14 pm-10:07 am

2 stops19h 53m

Charleston

Wed 6/3

6:18 pm-12:14 pm

2 stops18h 56m

$420

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

1:14 pm-11:55 pm

1 stop9h 41m

Charleston

Wed 6/3

1:00 pm-12:14 pm

2 stops24h 14m

$432

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

1:14 pm-10:07 am

2 stops19h 53m

Charleston

Wed 6/3

6:09 pm-12:14 pm

2 stops19h 05m

$433

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

1:14 pm-11:01 am

2 stops20h 47m

Charleston

Tue 6/16

6:18 pm-12:14 pm

2 stops18h 56m

$439

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

1:14 pm-11:55 pm

1 stop9h 41m

Charleston

Wed 6/3

6:09 pm-12:14 pm

2 stops19h 05m

$450

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

1:14 pm-1:07 pm

2 stops22h 53m

Charleston

Tue 6/16

6:18 pm-12:14 pm

2 stops18h 56m

$452

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

1:14 pm-11:55 pm

1 stop9h 41m

Charleston

Tue 6/16

3:12 pm-12:14 pm

2 stops22h 02m

$461

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

1:14 pm-11:55 pm

1 stop9h 41m

Charleston

Tue 6/16

3:12 pm-12:14 pm

2 stops22h 02m

$469

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Charleston from

How to get the cheapest flight ticket from Panama to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Panama is in December. Flight prices, which tend to average around $376, are often lower during this time because this is during the off-season. The month of August is another great option to travel to Charleston, with average flight prices from Panama averaging around $395.

Cheap Panama to Charleston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Charleston

Fastest flight time

11h 12m

Direct flights

None
The fastest flight from Panama to Charleston takes 11h 12m
There are no direct flights from Panama to Charleston. There are no popular flight routes from Panama to Charleston.
Search flight deals

  • When did momondo last update prices for flights from Panama to Charleston Airport?

    Prices for flights from Panama to Charleston Airport were last updated today.

  • How old do you have to be to fly from Panama to Charleston Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
Kiawah Island
North Charleston
Summerville
Mount Pleasant
Edisto Island
Santee
Walterboro
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Charleston?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama to Charleston for you.

Can I find flights from Panama to Charleston with flexible booking policies on momondo?

Yes. All flights to Charleston from Panama on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama to Charleston?

Once all potential Panama to Charleston flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to Charleston right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama to Charleston flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Charleston trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 3/13
Fri 3/20
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States