What is the cheapest airline that flies from Panama to Charleston?

Delta and United Airlines are the most popular carriers operating from Panama to Charleston

When did momondo last update prices for flights from Panama to Charleston Airport?

Prices for flights from Panama to Charleston Airport were last updated today.

How many operators does momondo search for flights from Panama to Charleston Airport?

There is 1 operator available for flights from Panama to Charleston Airport as of September 2026.

How old do you have to be to fly from Panama to Charleston Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama to Charleston Airport.

What documentation or ID do you need to fly to Charleston Airport?

The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$379 Cheap Flights from Panama to Charleston in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama to Charleston

Round-trip

One-way

Recent round-trip flight deals from Panama to Charleston

Enter your travel dates to find the best prices.

8:55 am - 9:21 pmPTY Panama City Tocumen Intl-CHS Charleston

12h 26m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

5:00 pm - 5:12 pmCHS Charleston-PTY Panama City Tocumen Intl

24h 12m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

$615United Airlines

Wed, Dec 2 - Mon, Dec 7

10:00 am - 10:06 amPTY Panama City Tocumen Intl-CHS Charleston

24h 06m2 stops Newark Washington, D.C. Dulles Intl

7:00 pm - 7:38 pmCHS Charleston-PTY Panama City Tocumen Intl

24h 38m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

$615United Airlines

Mon, Nov 23 - Mon, Nov 30

10:00 am - 2:20 pmPTY Panama City Tocumen Intl-CHS Charleston

28h 20m1 stop Newark

5:00 pm - 5:12 pmCHS Charleston-PTY Panama City Tocumen Intl

24h 12m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

$615United Airlines

Wed, Dec 2 - Mon, Dec 7

10:00 am - 2:20 pmPTY Panama City Tocumen Intl-CHS Charleston

28h 20m1 stop Newark

7:00 am - 8:02 pmCHS Charleston-PTY Panama City Tocumen Intl

13h 02m1 stop Newark

$615United Airlines

Wed, Dec 2 - Mon, Dec 7

8:55 am - 9:59 pmPTY Panama City Tocumen Intl-CHS Charleston

13h 04m1 stop Houston George Bush Intcntl

7:00 pm - 7:38 pmCHS Charleston-PTY Panama City Tocumen Intl

24h 38m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

$615United Airlines

Mon, Nov 23 - Mon, Nov 30

5:30 am - 7:32 pmPTY Panama City Tocumen Intl-CHS Charleston

13h 02m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

9:40 am - 2:10 amCHS Charleston-PTY Panama City Tocumen Intl

16h 30m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

$631Multiple Airlines

Sun, Oct 25 - Sun, Nov 1

3:50 pm - 10:15 amPTY Panama City Tocumen Intl-CHS Charleston

17h 25m2 stops San Salvador El Salvador Intl New York John F Kennedy Intl

8:33 pm - 10:30 amCHS Charleston-PTY Panama City Tocumen Intl

14h 57m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

$631Multiple Airlines

Mon, Oct 12 - Mon, Oct 19

11:30 am - 11:52 amPTY Panama City Tocumen Intl-CHS Charleston

24h 22m3 stops San José Juan Santamaria Intl Guatemala City La Aurora New York John F Kennedy Intl

7:40 am - 2:10 amCHS Charleston-PTY Panama City Tocumen Intl

18h 30m2 stops New York John F Kennedy Intl San Salvador El Salvador Intl

$657Multiple Airlines

Wed, Dec 2 - Mon, Dec 7

3:13 pm - 11:59 pmPTY Panama City Tocumen Intl-CHS Charleston

8h 46m1 stop Miami

8:14 pm - 2:13 pmCHS Charleston-PTY Panama City Tocumen Intl

17h 59m1 stop Miami

$674American Airlines

Mon, Nov 2 - Thu, Nov 5

3:13 pm - 10:02 pmPTY Panama City Tocumen Intl-CHS Charleston

6h 49m1 stop Miami

7:03 am - 2:13 pmCHS Charleston-PTY Panama City Tocumen Intl

7h 10m1 stop Miami

$685American Airlines

Wed, Nov 4 - Mon, Nov 9

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American Airlines flights from Panama to Charleston

Our best American Airlines deals on Panama to Charleston flight tickets

American Airlines

Nov 2

PTY3:13 pmPanama City Tocumen Intl

8h 46m

1 stop

CHS11:59 pmCharleston

Nov 5

CHS8:14 pmCharleston

17h 59m

1 stop

PTY2:13 pmPanama City Tocumen Intl

$674

American Airlines

Nov 4

PTY3:13 pmPanama City Tocumen Intl

6h 49m

1 stop

CHS10:02 pmCharleston

Nov 9

CHS7:03 amCharleston

7h 10m

1 stop

PTY2:13 pmPanama City Tocumen Intl

$685

American Airlines

Nov 2

PTY3:13 pmPanama City Tocumen Intl

8h 46m

1 stop

CHS11:59 pmCharleston

Nov 5

CHS8:14 pmCharleston

17h 59m

1 stop

PTY2:13 pmPanama City Tocumen Intl

$693

United Airlines flights from Panama to Charleston

Our best United Airlines deals on Panama to Charleston flight tickets

United Airlines

Dec 2

PTY10:00 amPanama City Tocumen Intl

28h 20m

1 stop

CHS2:20 pmCharleston

Dec 7

CHS5:00 pmCharleston

24h 12m

2 stops

PTY5:12 pmPanama City Tocumen Intl

$615

United Airlines

Nov 2

PTY10:00 amPanama City Tocumen Intl

27h 56m

2 stops

CHS1:56 pmCharleston

Nov 5

CHS7:52 pmCharleston

24h 10m

2 stops

PTY8:02 pmPanama City Tocumen Intl

$668

United Airlines

Nov 4

PTY8:55 amPanama City Tocumen Intl

13h 04m

1 stop

CHS9:59 pmCharleston

Nov 9

CHS7:00 pmCharleston

25h 02m

2 stops

PTY8:02 pmPanama City Tocumen Intl

$690

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Wed 12/2

8:55 am-9:21 pm

2 stops12h 26m

Charleston

Mon 12/7

5:00 pm-5:12 pm

2 stops24h 12m

$615

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Mon 11/23

10:00 am-10:06 am

2 stops24h 06m

Charleston

Mon 11/30

7:00 pm-7:38 pm

2 stops24h 38m

$615

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Wed 12/2

10:00 am-2:20 pm

1 stop28h 20m

Charleston

Mon 12/7

5:00 pm-5:12 pm

2 stops24h 12m

$615

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Wed 12/2

10:00 am-2:20 pm

1 stop28h 20m

Charleston

Mon 12/7

7:00 am-8:02 pm

1 stop13h 02m

$615

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Mon 11/23

8:55 am-9:59 pm

1 stop13h 04m

Charleston

Mon 11/30

7:00 pm-7:38 pm

2 stops24h 38m

$615

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Sun 10/25

5:30 am-7:32 pm

2 stops13h 02m

Charleston

Sun 11/1

9:40 am-2:10 am

2 stops16h 30m

$631

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Mon 10/12

3:50 pm-10:15 am

2 stops17h 25m

Charleston

Mon 10/19

8:33 pm-10:30 am

2 stops14h 57m

$631

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Wed 12/2

11:30 am-11:52 am

3 stops24h 22m

Charleston

Mon 12/7

7:40 am-2:10 am

2 stops18h 30m

$657

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Mon 11/2

3:13 pm-11:59 pm

1 stop8h 46m

Charleston

Thu 11/5

8:14 pm-2:13 pm

1 stop17h 59m

$674

Quickest round-trip

Panama CityCharleston

PTY Panama City Tocumen Intl - CHS Charleston

PTYCHS

Panama City Tocumen Intl

Wed 11/4

3:13 pm-10:02 pm

1 stop6h 49m

Charleston

Mon 11/9

7:03 am-2:13 pm

1 stop7h 10m

$685

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Panama is in October. Flight prices, which tend to average around $0, are often lower during this time because this is during the off-season. The month of December is another great option to travel to Charleston, with average flight prices from Panama averaging around $376.

Cheap Panama to Charleston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Charleston

Best Price Found	$379
Fastest flight time	13h 59m
Direct flights	None

The best one-way flight to Charleston from Panama in the past 72 hours is $379. The best round-trip flight deal from Panama to Charleston found on momondo in the last 72 hours is $615.

The fastest flight from Panama to Charleston takes 13h 59m

There are no direct flights from Panama to Charleston. There are no popular flight routes from Panama to Charleston.

Search flight deals

Frequently asked questions about flying from Panama to Charleston

When did momondo last update prices for flights from Panama to Charleston Airport?
Prices for flights from Panama to Charleston Airport were last updated today.
How many operators does momondo search for flights from Panama to Charleston Airport?
There is 1 operator available for flights from Panama to Charleston Airport as of September 2026.
How old do you have to be to fly from Panama to Charleston Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama to Charleston Airport.
What documentation or ID do you need to fly to Charleston Airport?
The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama to Charleston

Compare and see reviews for airlines that fly from Panama to Charleston with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $431	Free Cancellation	Rating 7.1 12,050 reviews		Search American Airlines flights

Folly Beach

North Charleston

Summerville

Isle of Palms

Mount Pleasant

Kiawah Island

Walterboro

Goose Creek

Edisto Island

Santee

Edisto Beach

Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Charleston?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama to Charleston for you.

Can I find flights from Panama to Charleston with flexible booking policies on momondo?

Yes. All flights to Charleston from Panama on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama to Charleston?

Once all potential Panama to Charleston flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to Charleston right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama to Charleston flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Charleston trip

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Cheap flights from Panama to Charleston from $379

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Charleston departing on 1/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Filter for what you want

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American Airlines flights from Panama to Charleston

Our best American Airlines deals on Panama to Charleston flight tickets

United Airlines flights from Panama to Charleston

Our best United Airlines deals on Panama to Charleston flight tickets

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How to get the cheapest flight ticket from Panama to Charleston

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Cheap Panama to Charleston flight deals and tips

Best Price Found

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Direct flights

Frequently asked questions about flying from Panama to Charleston

Best airlines flying from Panama to Charleston

Compare and see reviews for airlines that fly from Panama to Charleston with momondo

Traveling to a place near Charleston?

Why use momondo?

An easier way to manage your Charleston trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing South Carolina

Fly your favorite airline to Charleston

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Charleston

List of cabin classes available on flights landing in Charleston. Availability may vary depending on flight origin and airline.

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