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Cheap flights from Panama to Charleston from $241

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Charleston departing on 2/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama to Charleston

Recent round-trip flight deals from Panama to Charleston

Enter your travel dates to find the best prices.
United Airlines Logo
4:41 pm - 4:03 pm
PTY
-
CHS
23h 22m1 stop
United Airlines Logo
11:15 am - 8:02 pm
CHS
-
PTY
8h 47m1 stop
$396United Airlines
Sat, Feb 14 - Wed, Feb 18
American Airlines Logo
1:50 pm - 10:00 am
PTY
-
CHS
19h 10m2 stops
American Airlines Logo
6:32 pm - 12:25 pm
CHS
-
PTY
18h 53m2 stops
$397American Airlines
Fri, May 29 - Mon, Jun 1
American Airlines Logo
4:05 pm - 1:55 pm
PTY
-
CHS
21h 50m2 stops
American Airlines Logo
7:45 pm - 1:50 pm
CHS
-
PTY
18h 05m2 stops
$416American Airlines
Sat, Feb 14 - Wed, Feb 18
American Airlines Logo
1:50 pm - 10:16 am
PTY
-
CHS
19h 26m1 stop
American Airlines Logo
11:09 am - 12:25 pm
CHS
-
PTY
26h 16m1 stop
$450American Airlines
Fri, May 29 - Mon, Jun 1
American Airlines Logo
4:55 pm - 2:03 pm
PTY
-
CHS
21h 08m2 stops
American Airlines Logo
8:07 pm - 3:54 pm
CHS
-
PTY
19h 47m1 stop
$545American Airlines
Tue, Dec 30 - Thu, Jan 1
American Airlines Logo
4:55 pm - 8:47 am
PTY
-
CHS
15h 52m1 stop
American Airlines Logo
8:07 pm - 3:54 pm
CHS
-
PTY
19h 47m1 stop
$578American Airlines
Tue, Dec 30 - Thu, Jan 1
United Airlines Logo
4:41 pm - 4:10 pm
PTY
-
CHS
23h 29m1 stop
United Airlines Logo
5:00 pm - 2:45 pm
CHS
-
PTY
21h 45m1 stop
$580United Airlines
Tue, Dec 30 - Thu, Jan 1
United Airlines Logo
4:41 pm - 4:03 pm
PTY
-
CHS
23h 22m1 stop
United Airlines Logo
6:35 am - 2:45 pm
CHS
-
PTY
8h 10m1 stop
$610United Airlines
Wed, Feb 18 - Sun, Feb 22
United Airlines Logo
4:41 pm - 9:58 pm
PTY
-
CHS
29h 17m1 stop
United Airlines Logo
6:35 am - 7:38 pm
CHS
-
PTY
13h 03m1 stop
$692United Airlines
Wed, Feb 18 - Sun, Feb 22
Multiple Airlines Logo
9:45 am - 5:40 pm
PTY
-
CHS
31h 55m3 stops
Multiple Airlines Logo
5:00 pm - 6:55 pm
CHS
-
PTY
25h 55m2 stops
$821Multiple Airlines
Sat, Feb 14 - Wed, Feb 18

United Airlines flights from Panama to Charleston

Our best United Airlines deals on Panama to Charleston flight tickets
United Airlines
Feb 14
PTY4:41 pmPanama City Tocumen Intl
23h 22m
1 stop
CHS4:03 pmCharleston
Feb 18
CHS11:15 amCharleston
8h 47m
1 stop
PTY8:02 pmPanama City Tocumen Intl
$396
Find similar
United Airlines
Dec 30
PTY4:41 pmPanama City Tocumen Intl
23h 29m
1 stop
CHS4:10 pmCharleston
Jan 1
CHS5:00 pmCharleston
21h 45m
1 stop
PTY2:45 pmPanama City Tocumen Intl
$580
Find similar
United Airlines
Feb 18
PTY4:41 pmPanama City Tocumen Intl
23h 22m
1 stop
CHS4:03 pmCharleston
Feb 22
CHS6:35 amCharleston
8h 10m
1 stop
PTY2:45 pmPanama City Tocumen Intl
$610
Find similar

American Airlines flights from Panama to Charleston

Our best American Airlines deals on Panama to Charleston flight tickets
American Airlines
May 29
PTY1:50 pmPanama City Tocumen Intl
19h 10m
2 stops
CHS10:00 amCharleston
Jun 1
CHS6:32 pmCharleston
18h 53m
2 stops
PTY12:25 pmPanama City Tocumen Intl
$397
Find similar
American Airlines
Feb 14
PTY4:05 pmPanama City Tocumen Intl
21h 50m
2 stops
CHS1:55 pmCharleston
Feb 18
CHS7:45 pmCharleston
18h 05m
2 stops
PTY1:50 pmPanama City Tocumen Intl
$416
Find similar
American Airlines
May 29
PTY1:50 pmPanama City Tocumen Intl
19h 26m
1 stop
CHS10:16 amCharleston
Jun 1
CHS11:09 amCharleston
26h 16m
1 stop
PTY12:25 pmPanama City Tocumen Intl
$450
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Panama to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 2/14

4:41 pm-4:03 pm

1 stop23h 22m

Charleston

Wed 2/18

11:15 am-8:02 pm

1 stop8h 47m

$396

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 5/29

1:50 pm-10:00 am

2 stops19h 10m

Charleston

Mon 6/1

6:32 pm-12:25 pm

2 stops18h 53m

$397

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 2/14

4:05 pm-1:55 pm

2 stops21h 50m

Charleston

Wed 2/18

7:45 pm-1:50 pm

2 stops18h 05m

$416

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 5/29

1:50 pm-10:16 am

1 stop19h 26m

Charleston

Mon 6/1

11:09 am-12:25 pm

1 stop26h 16m

$450

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Tue 12/30

4:55 pm-2:03 pm

2 stops21h 08m

Charleston

Thu 1/1

8:07 pm-3:54 pm

1 stop19h 47m

$545

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Tue 12/30

4:55 pm-8:47 am

1 stop15h 52m

Charleston

Thu 1/1

8:07 pm-3:54 pm

1 stop19h 47m

$578

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Tue 12/30

4:41 pm-4:10 pm

1 stop23h 29m

Charleston

Thu 1/1

5:00 pm-2:45 pm

1 stop21h 45m

$580

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 2/18

4:41 pm-4:03 pm

1 stop23h 22m

Charleston

Sun 2/22

6:35 am-2:45 pm

1 stop8h 10m

$610

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 2/18

4:41 pm-9:58 pm

1 stop29h 17m

Charleston

Sun 2/22

6:35 am-7:38 pm

1 stop13h 03m

$692

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 2/14

9:45 am-5:40 pm

3 stops31h 55m

Charleston

Wed 2/18

5:00 pm-6:55 pm

2 stops25h 55m

$821

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
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See travel insights to Charleston from

How to get the cheapest flight ticket from Panama to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Panama to Charleston is on a Wednesday. Travelers who choose to depart for Charleston on a Wednesday will often find tickets for as low as $502. The most expensive day to fly to Charleston is Sunday, with ticket prices averaging around $552.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the evening when flights can be purchased for as low as $469. In the afternoon is when there is more demand to fly to Charleston, so prices are often more expensive at around $554 per ticket.

Cheap Panama to Charleston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Charleston

Fastest flight time

11h 55m

Direct flights

None
The fastest flight from Panama to Charleston takes 11h 55m
There are no direct flights from Panama to Charleston. There are no popular flight routes from Panama to Charleston.
Search flight deals

  • When did momondo last update prices for flights from Panama to Charleston Airport?

    Prices for flights from Panama to Charleston Airport were last updated today.

  • How old do you have to be to fly from Panama to Charleston Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Kiawah Island
Summerville
Mount Pleasant
Edisto Island
Santee
Walterboro
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Charleston?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama to Charleston for you.

Can I find flights from Panama to Charleston with flexible booking policies on momondo?

Yes. All flights to Charleston from Panama on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama to Charleston?

Once all potential Panama to Charleston flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to Charleston right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama to Charleston flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Charleston trip

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