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Cheap flights from Panama to Charleston from $343

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Charleston departing on 7/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama to Charleston

Recent round-trip flight deals from Panama to Charleston

Enter your travel dates to find the best prices.
United Airlines Logo
4:41 pm - 9:54 pm
PTY
-
CHS
29h 13m
1 stop
United Airlines Logo
6:05 am - 7:38 pm
CHS
-
PTY
13h 33m
2 stops
$562United Airlines
Mon, Dec 21 - Thu, Jan 21
United Airlines Logo
3:30 pm - 1:58 pm
PTY
-
CHS
21h 28m
2 stops
United Airlines Logo
7:00 am - 6:37 pm
CHS
-
PTY
12h 37m
1 stop
$590United Airlines
Thu, Aug 27 - Mon, Aug 31
Multiple Airlines Logo
3:50 pm - 10:08 am
PTY
-
CHS
17h 18m
2 stops
Multiple Airlines Logo
8:25 pm - 10:30 am
CHS
-
PTY
15h 05m
2 stops
$599Multiple Airlines
Fri, Aug 28 - Fri, Sep 4
United Airlines Logo
3:30 pm - 4:32 pm
PTY
-
CHS
24h 02m
1 stop
United Airlines Logo
3:15 pm - 4:04 am
CHS
-
PTY
13h 49m
1 stop
$605United Airlines
Thu, Aug 27 - Mon, Aug 31
Multiple Airlines Logo
3:50 pm - 10:08 am
PTY
-
CHS
17h 18m
2 stops
Multiple Airlines Logo
8:25 pm - 2:55 pm
CHS
-
PTY
19h 30m
3 stops
$606Multiple Airlines
Mon, Aug 17 - Fri, Aug 21
American Airlines Logo
4:56 pm - 8:47 am
PTY
-
CHS
15h 51m
1 stop
American Airlines Logo
9:27 am - 3:38 pm
CHS
-
PTY
6h 11m
1 stop
$610American Airlines
Sun, Dec 27 - Wed, Jan 13
American Airlines Logo
4:56 pm - 12:21 pm
PTY
-
CHS
19h 25m
2 stops
American Airlines Logo
6:00 am - 3:38 pm
CHS
-
PTY
9h 38m
1 stop
$615American Airlines
Sun, Dec 27 - Wed, Jan 13
Multiple Airlines Logo
3:50 pm - 10:08 am
PTY
-
CHS
17h 18m
2 stops
Multiple Airlines Logo
8:25 pm - 10:30 am
CHS
-
PTY
15h 05m
2 stops
$619Multiple Airlines
Mon, Aug 17 - Fri, Aug 21
United Airlines Logo
3:30 pm - 1:58 pm
PTY
-
CHS
21h 28m
2 stops
United Airlines Logo
3:15 pm - 4:04 am
CHS
-
PTY
13h 49m
1 stop
$632United Airlines
Mon, Aug 17 - Fri, Aug 21
Multiple Airlines Logo
3:50 pm - 10:08 am
PTY
-
CHS
17h 18m
2 stops
Multiple Airlines Logo
8:25 pm - 2:55 pm
CHS
-
PTY
19h 30m
3 stops
$647Multiple Airlines
Fri, Aug 28 - Fri, Sep 4

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United Airlines flights from Panama to Charleston

Our best United Airlines deals on Panama to Charleston flight tickets
United Airlines
Dec 21
PTY4:41 pmPanama City Tocumen Intl
29h 13m
1 stop
CHS9:54 pmCharleston
Jan 21
CHS6:05 amCharleston
13h 33m
2 stops
PTY7:38 pmPanama City Tocumen Intl
$562
United Airlines
Aug 27
PTY3:30 pmPanama City Tocumen Intl
21h 28m
2 stops
CHS1:58 pmCharleston
Aug 31
CHS7:00 amCharleston
12h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
$590
United Airlines
Aug 27
PTY3:30 pmPanama City Tocumen Intl
24h 02m
1 stop
CHS4:32 pmCharleston
Aug 31
CHS3:15 pmCharleston
13h 49m
1 stop
PTY4:04 amPanama City Tocumen Intl
$605

American Airlines flights from Panama to Charleston

Our best American Airlines deals on Panama to Charleston flight tickets
American Airlines
Dec 27
PTY4:56 pmPanama City Tocumen Intl
15h 51m
1 stop
CHS8:47 amCharleston
Jan 13
CHS9:27 amCharleston
6h 11m
1 stop
PTY3:38 pmPanama City Tocumen Intl
$610
American Airlines
Dec 27
PTY4:56 pmPanama City Tocumen Intl
19h 25m
2 stops
CHS12:21 pmCharleston
Jan 13
CHS6:00 amCharleston
9h 38m
1 stop
PTY3:38 pmPanama City Tocumen Intl
$615
American Airlines
Jul 16
PTY1:14 pmPanama City Tocumen Intl
19h 53m
2 stops
CHS10:07 amCharleston
Aug 29
CHS4:10 pmCharleston
21h 29m
2 stops
PTY12:39 pmPanama City Tocumen Intl
$868

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 15, 2026.
Use the filters below to find and compare flights from Panama to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 12/21

4:41 pm-9:54 pm

1 stop29h 13m

Charleston

Thu 1/21

6:05 am-7:38 pm

2 stops13h 33m

$562

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 8/27

3:30 pm-1:58 pm

2 stops21h 28m

Charleston

Mon 8/31

7:00 am-6:37 pm

1 stop12h 37m

$590

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 8/28

3:50 pm-10:08 am

2 stops17h 18m

Charleston

Fri 9/4

8:25 pm-10:30 am

2 stops15h 05m

$599

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 8/27

3:30 pm-4:32 pm

1 stop24h 02m

Charleston

Mon 8/31

3:15 pm-4:04 am

1 stop13h 49m

$605

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 8/17

3:50 pm-10:08 am

2 stops17h 18m

Charleston

Fri 8/21

8:25 pm-2:55 pm

3 stops19h 30m

$606
Quickest round-trip

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 12/27

4:56 pm-8:47 am

1 stop15h 51m

Charleston

Wed 1/13

9:27 am-3:38 pm

1 stop6h 11m

$610

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 12/27

4:56 pm-12:21 pm

2 stops19h 25m

Charleston

Wed 1/13

6:00 am-3:38 pm

1 stop9h 38m

$615

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 8/17

3:50 pm-10:08 am

2 stops17h 18m

Charleston

Fri 8/21

8:25 pm-10:30 am

2 stops15h 05m

$619

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 8/17

3:30 pm-1:58 pm

2 stops21h 28m

Charleston

Fri 8/21

3:15 pm-4:04 am

1 stop13h 49m

$632

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 8/28

3:50 pm-10:08 am

2 stops17h 18m

Charleston

Fri 9/4

8:25 pm-2:55 pm

3 stops19h 30m

$647

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Charleston from

How to get the cheapest flight ticket from Panama to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Panama is in December. Flight prices, which tend to average around $148, are often lower during this time because this is during the off-season. The month of February is another great option to travel to Charleston, with average flight prices from Panama averaging around $158.

Cheap Panama to Charleston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Charleston

Fastest flight time

13h 46m

Direct flights

None
The fastest flight from Panama to Charleston takes 13h 46m
There are no direct flights from Panama to Charleston. There are no popular flight routes from Panama to Charleston.
Search flight deals

Frequently asked questions about flying from Panama to Charleston

  • When did momondo last update prices for flights from Panama to Charleston Airport?

    Prices for flights from Panama to Charleston Airport were last updated today.

  • How many operators does momondo search for flights from Panama to Charleston Airport?

  • How old do you have to be to fly from Panama to Charleston Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama to Charleston

Compare and see reviews for airlines that fly from Panama to Charleston with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $397Free CancellationRating
7.1
11,807 reviews
Search American Airlines flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
North Charleston
Summerville
Isle of Palms
Kiawah Island
Mount Pleasant
Santee
Walterboro
Edisto Island
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Charleston?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama to Charleston for you.

Can I find flights from Panama to Charleston with flexible booking policies on momondo?

Yes. All flights to Charleston from Panama on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama to Charleston?

Once all potential Panama to Charleston flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to Charleston right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama to Charleston flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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