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Cheap flights from Panama to Charleston from $405

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Charleston departing on 10/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama to Charleston

Recent round-trip flight deals from Panama to Charleston

American Airlines Logo
3:15 pm - 11:59 pmPTY-CHS
7h 44m1 stop
American Airlines Logo
6:00 am - 2:03 pmCHS-PTY
9h 03m1 stop
$405American Airlines
Find Deal
Fri, Oct 10 - Sun, Oct 12
American Airlines Logo
3:15 pm - 11:59 pmPTY-CHS
7h 44m1 stop
American Airlines Logo
7:05 pm - 2:03 pmCHS-PTY
19h 58m2 stops
$409American Airlines
Find Deal
Fri, Oct 10 - Sun, Oct 12
American Airlines Logo
3:15 pm - 7:04 pmPTY-CHS
26h 49m1 stop
American Airlines Logo
6:00 am - 1:36 pmCHS-PTY
7h 36m1 stop
$412American Airlines
Find Deal
Tue, Oct 21 - Sat, Nov 15
American Airlines Logo
3:15 pm - 1:12 pmPTY-CHS
20h 57m2 stops
American Airlines Logo
6:00 am - 1:36 pmCHS-PTY
7h 36m1 stop
$416American Airlines
Find Deal
Tue, Oct 21 - Sat, Nov 15
American Airlines Logo
3:15 pm - 7:04 pmPTY-CHS
26h 49m1 stop
American Airlines Logo
9:27 am - 1:36 pmCHS-PTY
28h 09m1 stop
$431American Airlines
Find Deal
Mon, Oct 20 - Sun, Nov 16
American Airlines Logo
3:15 pm - 1:45 pmPTY-CHS
21h 30m2 stops
American Airlines Logo
6:32 pm - 1:36 pmCHS-PTY
19h 04m2 stops
$436American Airlines
Find Deal
Mon, Oct 20 - Sun, Nov 16
American Airlines Logo
3:15 pm - 9:01 amPTY-CHS
16h 46m1 stop
American Airlines Logo
6:00 am - 2:03 pmCHS-PTY
9h 03m1 stop
$440American Airlines
Find Deal
Sun, Oct 19 - Sun, Oct 26
Delta Logo
2:21 pm - 10:38 pmPTY-CHS
7h 17m1 stop
Delta Logo
6:40 am - 12:56 pmCHS-PTY
7h 16m1 stop
$449Delta
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Mon, Oct 20 - Mon, Oct 27
Delta Logo
2:21 pm - 11:59 pmPTY-CHS
8h 38m1 stop
Delta Logo
8:50 am - 12:56 pmCHS-PTY
29h 06m1 stop
$468Delta
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Mon, Oct 20 - Sat, Oct 25
Logo
3:25 am - 9:26 amPTY-CHS
29h 01m2 stops
Logo
10:31 am - 8:19 pmCHS-PTY
10h 48m1 stop
$716
Find Deal
Fri, Oct 17 - Mon, Oct 27

American Airlines flights from Panama to Charleston

Our best American Airlines deals on Panama to Charleston flight tickets
American Airlines
Oct 10
PTY3:15 pmPanama City Tocumen Intl
7h 44m
1 stop
CHS11:59 pmCharleston
Oct 12
CHS6:00 amCharleston
9h 03m
1 stop
PTY2:03 pmPanama City Tocumen Intl
$405
Find similar
American Airlines
Oct 10
PTY3:15 pmPanama City Tocumen Intl
7h 44m
1 stop
CHS11:59 pmCharleston
Oct 12
CHS7:05 pmCharleston
19h 58m
2 stops
PTY2:03 pmPanama City Tocumen Intl
$409
Find similar
American Airlines
Oct 21
PTY3:15 pmPanama City Tocumen Intl
26h 49m
1 stop
CHS7:04 pmCharleston
Nov 15
CHS6:00 amCharleston
7h 36m
1 stop
PTY1:36 pmPanama City Tocumen Intl
$412
Find similar

Delta flights from Panama to Charleston

Our best Delta deals on Panama to Charleston flight tickets
Delta
Oct 20
PTY2:21 pmPanama City Tocumen Intl
7h 17m
1 stop
CHS10:38 pmCharleston
Oct 27
CHS6:40 amCharleston
7h 16m
1 stop
PTY12:56 pmPanama City Tocumen Intl
$449
Find similar
Delta
Oct 20
PTY2:21 pmPanama City Tocumen Intl
8h 38m
1 stop
CHS11:59 pmCharleston
Oct 25
CHS8:50 amCharleston
29h 06m
1 stop
PTY12:56 pmPanama City Tocumen Intl
$468
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Panama to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 10/10

3:15 pm-11:59 pm

1 stop7h 44m

Charleston

Sun 10/12

6:00 am-2:03 pm

1 stop9h 03m

$405

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 10/10

3:15 pm-11:59 pm

1 stop7h 44m

Charleston

Sun 10/12

7:05 pm-2:03 pm

2 stops19h 58m

$409

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Tue 10/21

3:15 pm-7:04 pm

1 stop26h 49m

Charleston

Sat 11/15

6:00 am-1:36 pm

1 stop7h 36m

$412

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Tue 10/21

3:15 pm-1:12 pm

2 stops20h 57m

Charleston

Sat 11/15

6:00 am-1:36 pm

1 stop7h 36m

$416

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 10/20

3:15 pm-7:04 pm

1 stop26h 49m

Charleston

Sun 11/16

9:27 am-1:36 pm

1 stop28h 09m

$431

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 10/20

3:15 pm-1:45 pm

2 stops21h 30m

Charleston

Sun 11/16

6:32 pm-1:36 pm

2 stops19h 04m

$436

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 10/19

3:15 pm-9:01 am

1 stop16h 46m

Charleston

Sun 10/26

6:00 am-2:03 pm

1 stop9h 03m

$440

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 10/20

2:21 pm-10:38 pm

1 stop7h 17m

Charleston

Mon 10/27

6:40 am-12:56 pm

1 stop7h 16m

$449

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 10/20

2:21 pm-11:59 pm

1 stop8h 38m

Charleston

Sat 10/25

8:50 am-12:56 pm

1 stop29h 06m

$468

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 10/17

3:25 am-9:26 am

2 stops29h 01m

Charleston

Mon 10/27

10:31 am-8:19 pm

1 stop10h 48m

$716

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Charleston from

How to get the cheapest flight ticket from Panama to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Panama to Charleston is on a Wednesday. Travelers who choose to depart for Charleston on a Wednesday will often find tickets for as low as $502. The most expensive day to fly to Charleston is Sunday, with ticket prices averaging around $552.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the evening when flights can be purchased for as low as $469. In the afternoon is when there is more demand to fly to Charleston, so prices are often more expensive at around $554 per ticket.

Cheap Panama to Charleston flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Charleston

Direct flights

None
There are no direct flights from Panama to Charleston. There are no popular flight routes from Panama to Charleston.
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  • When did momondo last update prices for flights from Panama to Charleston Airport?

    Prices for flights from Panama to Charleston Airport were last updated today.

  • How many operators does momondo search for flights from Panama to Charleston Airport?

  • How old do you have to be to fly from Panama to Charleston Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The required travel and health documents for your Charleston Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Charleston Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama to Charleston

Compare and see reviews for airlines that fly from Panama to Charleston with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $397Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Kiawah Island
Summerville
Mount Pleasant
Edisto Island
Walterboro
Goose Creek
Santee
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Charleston?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama to Charleston for you.

Can I find flights from Panama to Charleston with flexible booking policies on momondo?

Yes. All flights to Charleston from Panama on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama to Charleston?

Once all potential Panama to Charleston flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama to Charleston right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama to Charleston flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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