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Cheap flights from Panama to Cleveland from $526

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Cleveland departing on 5/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Panama to Cleveland

Recent round-trip flight deals from Panama to Cleveland

Enter your travel dates to find the best prices.
Delta Logo
2:20 pm - 12:37 am
PTY
-
CLE
9h 17m1 stop
Delta Logo
6:00 am - 12:55 pm
CLE
-
PTY
7h 55m1 stop
$526Delta
Fri, May 1 - Thu, May 7
American Airlines Logo
1:55 pm - 12:32 pm
PTY
-
CLE
21h 37m2 stops
American Airlines Logo
2:05 pm - 12:15 pm
CLE
-
PTY
23h 10m2 stops
$527American Airlines
Fri, May 1 - Thu, May 7
American Airlines Logo
1:55 pm - 12:02 pm
PTY
-
CLE
21h 07m2 stops
American Airlines Logo
6:28 am - 12:15 pm
CLE
-
PTY
6h 47m1 stop
$571American Airlines
Fri, May 1 - Thu, May 7
United Airlines Logo
8:55 am - 10:02 pm
PTY
-
CLE
13h 07m1 stop
United Airlines Logo
6:00 am - 5:07 pm
CLE
-
PTY
11h 07m1 stop
$578United Airlines
Sat, Jan 24 - Tue, Jan 27
Multiple Airlines Logo
10:05 pm - 8:36 pm
PTY
-
CLE
21h 31m3 stops
Multiple Airlines Logo
5:35 pm - 12:45 am
CLE
-
PTY
32h 10m3 stops
$1,086Multiple Airlines
Fri, May 1 - Thu, May 7
Multiple Airlines Logo
10:05 pm - 8:36 pm
PTY
-
CLE
21h 31m3 stops
Multiple Airlines Logo
7:00 pm - 10:10 am
CLE
-
PTY
16h 10m2 stops
$1,722Multiple Airlines
Fri, May 1 - Thu, May 7

United Airlines flights from Panama to Cleveland

Our best United Airlines deals on Panama to Cleveland flight tickets
United Airlines
Jan 24
PTY4:41 pmPanama City Tocumen Intl
18h 27m
1 stop
CLE11:08 amCleveland Hopkins Intl
Jan 27
CLE6:00 amCleveland Hopkins Intl
8h 45m
1 stop
PTY2:45 pmPanama City Tocumen Intl
$578
Find similar
United Airlines
Dec 18
PTY11:35 amPanama City Tocumen Intl
10h 20m
1 stop
CLE9:55 pmCleveland Hopkins Intl
Dec 20
CLE6:00 amCleveland Hopkins Intl
13h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
$673
Find similar

American Airlines flights from Panama to Cleveland

Our best American Airlines deals on Panama to Cleveland flight tickets
American Airlines
May 1
PTY1:55 pmPanama City Tocumen Intl
21h 37m
2 stops
CLE12:32 pmCleveland Hopkins Intl
May 7
CLE2:05 pmCleveland Hopkins Intl
23h 10m
2 stops
PTY12:15 pmPanama City Tocumen Intl
$527
Find similar
American Airlines
May 1
PTY1:55 pmPanama City Tocumen Intl
21h 07m
2 stops
CLE12:02 pmCleveland Hopkins Intl
May 7
CLE6:28 amCleveland Hopkins Intl
6h 47m
1 stop
PTY12:15 pmPanama City Tocumen Intl
$571
Find similar
American Airlines
Dec 22
PTY2:53 pmPanama City Tocumen Intl
9h 06m
1 stop
CLE11:59 pmCleveland Hopkins Intl
Dec 27
CLE7:59 pmCleveland Hopkins Intl
19h 55m
2 stops
PTY3:54 pmPanama City Tocumen Intl
$708
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Panama to Cleveland that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 5/1

2:20 pm-12:37 am

1 stop9h 17m

Cleveland Hopkins Intl

Thu 5/7

6:00 am-12:55 pm

1 stop7h 55m

$526

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 5/1

1:55 pm-12:32 pm

2 stops21h 37m

Cleveland Hopkins Intl

Thu 5/7

2:05 pm-12:15 pm

2 stops23h 10m

$527

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 5/1

1:55 pm-12:02 pm

2 stops21h 07m

Cleveland Hopkins Intl

Thu 5/7

6:28 am-12:15 pm

1 stop6h 47m

$571

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sat 1/24

8:55 am-10:02 pm

1 stop13h 07m

Cleveland Hopkins Intl

Tue 1/27

6:00 am-5:07 pm

1 stop11h 07m

$578

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 5/1

10:05 pm-8:36 pm

3 stops21h 31m

Cleveland Hopkins Intl

Thu 5/7

5:35 pm-12:45 am

3 stops32h 10m

$1,086

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 5/1

10:05 pm-8:36 pm

3 stops21h 31m

Cleveland Hopkins Intl

Thu 5/7

7:00 pm-10:10 am

2 stops16h 10m

$1,722

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Cleveland from

How to get the cheapest flight ticket from Panama to Cleveland

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Cleveland?

In general, January is the cheapest month to fly from Panama to Cleveland. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $496. If you’re not able to fly to Cleveland in January, then November is your next best option. Flight prices from Panama to Cleveland during November average around $504.

What is the cheapest day to depart on your flight to Cleveland?

The cheapest day to depart from Panama to Cleveland is on a Wednesday when prices can be found for as low as $504. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Cleveland on Friday is $680.

What is the cheapest time of day to depart on your flight to Cleveland?

Our data shows that the cheapest Panama to Cleveland flights are usually those with departure times in the afternoon. Our users have found flights to Cleveland in the afternoon for as low as $517. In contrast, the most expensive time of day to depart to Cleveland is in the morning when prices are around $586.

Can stopping save me money on Panama to Cleveland flights?

You could potentially save up to 48% on your flight if you consider stops on a Panama to Cleveland flight.

Cheap Panama to Cleveland flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Cleveland

Fastest flight time

11h 17m

Direct flights

None
The fastest flight from Panama to Cleveland takes 11h 17m
There are no direct flights from Panama to Cleveland. There are no popular flight routes from Panama to Cleveland.
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  • When did momondo last update prices for flights from Panama to Cleveland Hopkins Intl Airport?

    Prices for flights from Panama to Cleveland Hopkins Intl Airport were last updated today.

  • How many operators does momondo search for flights from Panama to Cleveland Hopkins Intl Airport?

  • How old do you have to be to fly from Panama to Cleveland Hopkins Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama to Cleveland Hopkins Intl Airport.

  • What documentation or ID do you need to fly to Cleveland Hopkins Intl Airport?

    The required travel and health documents for your Cleveland Hopkins Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Cleveland Hopkins Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Panama to Cleveland

Compare and see reviews for airlines that fly from Panama to Cleveland with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $483Free CancellationRating
7.9
8,010 reviews
Search Delta flights
United AirlinesPriceFrom $613Free CancellationRating
7.4
9,094 reviews
Search United Airlines flights

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Beachwood
Mansfield
Elyria
Mentor
Geneva-on-the-Lake
Independence
Westlake
Kent
Wooster
North Olmsted
Streetsboro
Willoughby
Cuyahoga Falls
Painesville
Lakewood
Ashland
Medina
Kelleys Island
Avon

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Cleveland?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama to Cleveland. momondo saves you time and could save you money on your trip.

Can I find flights from Panama to Cleveland with flexible booking policies on momondo?

Yes. All flights to Cleveland from Panama on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Panama to Cleveland?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Cleveland from Panama.

I’m not ready to book a flight from Panama to Cleveland right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama to Cleveland flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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