Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City to Louisville from $281

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Louisville departing on 12/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
3:20 pm - 1:33 pm
PTY
-
SDF
21h 13m1 stop
United Airlines Logo
6:00 pm - 2:14 pm
SDF
-
PTY
21h 14m2 stops
$449United Airlines
Fri, May 1 - Mon, May 11
Delta Logo
3:20 pm - 11:50 pm
PTY
-
SDF
8h 30m1 stop
Delta Logo
5:35 am - 1:55 pm
SDF
-
PTY
8h 20m1 stop
$458Delta
Wed, Jan 21 - Sun, Jan 25
United Airlines Logo
4:41 pm - 1:28 pm
PTY
-
SDF
20h 47m2 stops
United Airlines Logo
9:15 am - 5:07 pm
SDF
-
PTY
7h 52m1 stop
$463United Airlines
Wed, Jan 21 - Sun, Jan 25
American Airlines Logo
4:05 pm - 11:59 pm
PTY
-
SDF
7h 54m1 stop
American Airlines Logo
6:01 am - 3:15 pm
SDF
-
PTY
9h 14m1 stop
$472American Airlines
Thu, Feb 12 - Thu, Feb 26
United Airlines Logo
4:41 pm - 9:59 pm
PTY
-
SDF
29h 18m1 stop
United Airlines Logo
8:30 am - 8:02 pm
SDF
-
PTY
11h 32m1 stop
$475United Airlines
Wed, Jan 21 - Sun, Jan 25
American Airlines Logo
4:05 pm - 10:05 am
PTY
-
SDF
18h 00m2 stops
American Airlines Logo
7:47 pm - 3:15 pm
SDF
-
PTY
19h 28m2 stops
$476American Airlines
Thu, Feb 12 - Thu, Feb 26
United Airlines Logo
8:55 am - 9:59 pm
PTY
-
SDF
13h 04m1 stop
United Airlines Logo
9:15 am - 5:07 pm
SDF
-
PTY
7h 52m1 stop
$508United Airlines
Wed, Jan 21 - Sun, Jan 25
United Airlines Logo
4:41 pm - 1:28 pm
PTY
-
SDF
20h 47m2 stops
United Airlines Logo
5:35 am - 7:38 pm
SDF
-
PTY
14h 03m2 stops
$512United Airlines
Wed, Jan 21 - Sun, Jan 25
American Airlines Logo
2:53 pm - 8:50 am
PTY
-
SDF
17h 57m2 stops
American Airlines Logo
6:19 pm - 1:53 pm
SDF
-
PTY
19h 34m2 stops
$536American Airlines
Fri, Dec 26 - Fri, Jan 2
Delta Logo
8:00 am - 3:59 pm
PTY
-
SDF
7h 59m1 stop
Delta Logo
10:14 am - 8:00 pm
SDF
-
PTY
9h 46m1 stop
$543Delta
Fri, Dec 26 - Fri, Jan 2

Delta flights from Panama City to Louisville

Our best Delta deals on Panama City to Louisville flight tickets
Delta
Jan 21
PTY3:20 pmPanama City Tocumen Intl
8h 30m
1 stop
SDF11:50 pmLouisville Intl
Jan 25
SDF5:35 amLouisville Intl
8h 20m
1 stop
PTY1:55 pmPanama City Tocumen Intl
$458
Find similar
Delta
Dec 26
PTY8:00 amPanama City Tocumen Intl
7h 59m
1 stop
SDF3:59 pmLouisville Intl
Jan 2
SDF10:14 amLouisville Intl
9h 46m
1 stop
PTY8:00 pmPanama City Tocumen Intl
$543
Find similar
Delta
May 1
PTY2:20 pmPanama City Tocumen Intl
7h 17m
1 stop
SDF10:37 pmLouisville Intl
May 11
SDF7:00 amLouisville Intl
6h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
$549
Find similar

United Airlines flights from Panama City to Louisville

Our best United Airlines deals on Panama City to Louisville flight tickets
United Airlines
May 1
PTY3:20 pmPanama City Tocumen Intl
21h 13m
1 stop
SDF1:33 pmLouisville Intl
May 11
SDF6:00 pmLouisville Intl
21h 14m
2 stops
PTY2:14 pmPanama City Tocumen Intl
$449
Find similar
United Airlines
Jan 21
PTY4:41 pmPanama City Tocumen Intl
20h 47m
2 stops
SDF1:28 pmLouisville Intl
Jan 25
SDF9:15 amLouisville Intl
7h 52m
1 stop
PTY5:07 pmPanama City Tocumen Intl
$463
Find similar
United Airlines
Jan 21
PTY4:41 pmPanama City Tocumen Intl
29h 18m
1 stop
SDF9:59 pmLouisville Intl
Jan 25
SDF8:30 amLouisville Intl
11h 32m
1 stop
PTY8:02 pmPanama City Tocumen Intl
$475
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Panama City to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 5/1

3:20 pm-1:33 pm

1 stop21h 13m

Louisville Intl

Mon 5/11

6:00 pm-2:14 pm

2 stops21h 14m

$449

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 1/21

3:20 pm-11:50 pm

1 stop8h 30m

Louisville Intl

Sun 1/25

5:35 am-1:55 pm

1 stop8h 20m

$458

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 1/21

4:41 pm-1:28 pm

2 stops20h 47m

Louisville Intl

Sun 1/25

9:15 am-5:07 pm

1 stop7h 52m

$463

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Thu 2/12

4:05 pm-11:59 pm

1 stop7h 54m

Louisville Intl

Thu 2/26

6:01 am-3:15 pm

1 stop9h 14m

$472

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 1/21

4:41 pm-9:59 pm

1 stop29h 18m

Louisville Intl

Sun 1/25

8:30 am-8:02 pm

1 stop11h 32m

$475

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Thu 2/12

4:05 pm-10:05 am

2 stops18h 00m

Louisville Intl

Thu 2/26

7:47 pm-3:15 pm

2 stops19h 28m

$476

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 1/21

8:55 am-9:59 pm

1 stop13h 04m

Louisville Intl

Sun 1/25

9:15 am-5:07 pm

1 stop7h 52m

$508

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 1/21

4:41 pm-1:28 pm

2 stops20h 47m

Louisville Intl

Sun 1/25

5:35 am-7:38 pm

2 stops14h 03m

$512

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 12/26

2:53 pm-8:50 am

2 stops17h 57m

Louisville Intl

Fri 1/2

6:19 pm-1:53 pm

2 stops19h 34m

$536

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 12/26

8:00 am-3:59 pm

1 stop7h 59m

Louisville Intl

Fri 1/2

10:14 am-8:00 pm

1 stop9h 46m

$543

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

See travel insights to Louisville from

How to get the cheapest flight ticket from Panama City to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Louisville?

What is the cheapest month to fly to Louisville?

If you are unable to visit Louisville during the month of October, then departing from Panama City during the month February is also very affordable. Most momondo users find prices during this month for around $478.

What is the cheapest day to depart on your flight to Louisville?

On average, the least expensive day to fly to Louisville from Panama City is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $496. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from Panama City to Louisville on a Sunday will generally be more expensive and average around $968. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Louisville?

Our data shows that the cheapest Panama City to Louisville flights are usually those with departure times in the afternoon. Our users have found flights to Louisville in the afternoon for as low as $620. In the morning is when there is more demand to fly to Louisville, so prices are often more expensive at around $683 per ticket.

When to book flights from Panama City to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Louisville (PTY to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Louisville

Fastest flight time

13h 02m

Direct flights

None
The fastest flight from Panama City to Louisville takes 13h 02m
There are no direct flights from Panama City to Louisville. There are no popular flight routes from Panama City to Louisville.
Search flight deals

  • How far is Panama City Tocumen Intl to Louisville Intl by plane?

    Panama City Tocumen Intl and Louisville Intl are 2057.4 mi apart from one another. A reasonable flight in good conditions will take 7h 17m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Louisville Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Louisville Intl Airport are updated daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Louisville Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The travel and health documents required for your trip to Louisville Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Louisville Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Panama City to Louisville?

Best airlines flying from Panama City to Louisville

Compare and see reviews for airlines that fly from Panama City to Louisville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $366Free CancellationRating
7.4
9,063 reviews
Search United Airlines flights

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
West Baden Springs
Bardstown
Jeffersonville
Shepherdsville
New Albany
Corydon
Elizabeth
Charlestown
Springfield
Brandenburg
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Louisville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Louisville. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Louisville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Louisville from Panama City with this policy.

How can momondo help me find flights from Panama City to Louisville?

Once you have performed a search for Panama City to Louisville flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Louisville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Louisville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Louisville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 1/3
Sat 1/10
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States