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Cheap flights from Panama City to Santo Domingo from $162

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Santo Domingo departing on 6/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City to Santo Domingo

Cheap round-trip flights

Avianca Logo
3:25 am - 5:15 pmPTY-SDQ
12h 50m1 stop
Avianca Logo
11:45 am - 12:10 amSDQ-PTY
13h 25m1 stop
$294Avianca
Find Deal
Mon, Jun 30 - Tue, Jul 8
Avianca Logo
3:25 am - 10:50 amPTY-SDQ
6h 25m1 stop
Avianca Logo
6:10 pm - 12:10 amSDQ-PTY
7h 00m1 stop
$295Avianca
Find Deal
Fri, Jun 27 - Sat, Jul 12
 Logo
5:25 pm - 2:50 pmPTY-SDQ
20h 25m2 stops
 Logo
11:45 am - 12:10 amSDQ-PTY
13h 25m1 stop
Thu, Oct 9 - Thu, Oct 23
 Logo
5:25 pm - 10:50 amPTY-SDQ
16h 25m1 stop
 Logo
6:32 pm - 12:10 amSDQ-PTY
30h 38m2 stops
Mon, Aug 4 - Mon, Aug 18
Copa Airlines Logo
7:26 am - 10:59 amPTY-SDQ
2h 33mnonstop
Copa Airlines Logo
2:07 pm - 3:42 pmSDQ-PTY
2h 35mnonstop
$429Copa Airlines
Find Deal
Thu, Jul 3 - Thu, Jul 10
Copa Airlines Logo
6:55 pm - 10:26 pmPTY-SDQ
2h 31mnonstop
Copa Airlines Logo
12:14 pm - 1:51 pmSDQ-PTY
2h 37mnonstop
$445Copa Airlines
Find Deal
Fri, Oct 31 - Wed, Nov 5
United Airlines Logo
3:30 pm - 1:50 amPTY-SDQ
33h 20m2 stops
United Airlines Logo
1:10 pm - 2:14 pmSDQ-PTY
26h 04m2 stops
$1,272United Airlines
Find Deal
Mon, Sep 22 - Mon, Sep 29
United Airlines Logo
11:35 am - 2:49 amPTY-SDQ
38h 14m3 stops
United Airlines Logo
2:55 pm - 2:45 pmSDQ-PTY
24h 50m2 stops
$1,462United Airlines
Find Deal
Tue, Dec 2 - Sat, Dec 6
Delta Logo
3:17 pm - 6:39 pmPTY-SDQ
26h 22m2 stops
Delta Logo
2:55 pm - 1:52 pmSDQ-PTY
23h 57m2 stops
$5,776Delta
Find Deal
Thu, Nov 13 - Tue, Nov 18
Delta Logo
2:14 pm - 12:30 amPTY-SDQ
33h 16m2 stops
Delta Logo
2:09 pm - 12:49 pmSDQ-PTY
23h 40m2 stops
$5,822Delta
Find Deal
Thu, Sep 18 - Mon, Sep 22

Avianca flights from Panama City to Santo Domingo

Our best Avianca deals on Panama City to Santo Domingo flight tickets
Avianca
Jun 30
PTY3:25 amPanama City Tocumen Intl
12h 50m
1 stop
SDQ5:15 pmSanto Domingo Las Americas
Jul 8
SDQ11:45 amSanto Domingo Las Americas
13h 25m
1 stop
PTY12:10 amPanama City Tocumen Intl
Avianca
Jun 27
PTY3:25 amPanama City Tocumen Intl
6h 25m
1 stop
SDQ10:50 amSanto Domingo Las Americas
Jul 12
SDQ6:10 pmSanto Domingo Las Americas
7h 00m
1 stop
PTY12:10 amPanama City Tocumen Intl
Avianca
Jul 2
PTY3:20 amPanama City Tocumen Intl
6h 30m
1 stop
SDQ10:50 amSanto Domingo Las Americas
Jul 6
SDQ6:10 pmSanto Domingo Las Americas
7h 00m
1 stop
PTY12:10 amPanama City Tocumen Intl

Copa Airlines flights from Panama City to Santo Domingo

Our best Copa Airlines deals on Panama City to Santo Domingo flight tickets
Copa Airlines
Jun 26
PTY6:55 pmPanama City Tocumen Intl
2h 32m
SDQ10:27 pmSanto Domingo Las Americas
Jun 30
SDQ11:52 amSanto Domingo Las Americas
2h 37m
PTY1:29 pmPanama City Tocumen Intl
Copa Airlines
Oct 31
PTY6:55 pmPanama City Tocumen Intl
2h 31m
SDQ10:26 pmSanto Domingo Las Americas
Nov 5
SDQ12:14 pmSanto Domingo Las Americas
2h 37m
PTY1:51 pmPanama City Tocumen Intl
Copa Airlines
Jun 24
PTY6:55 pmPanama City Tocumen Intl
2h 32m
SDQ10:27 pmSanto Domingo Las Americas
Jul 7
SDQ5:39 pmSanto Domingo Las Americas
2h 35m
PTY7:14 pmPanama City Tocumen Intl

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Panama City to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in July, then you should wait until August to fly from Panama City, when ticket prices are also cheap, with an average price of $393.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Thursday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $414. The most expensive day to fly to Santo Domingo is Sunday, with ticket prices averaging around $460.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the afternoon when flights can be purchased for as low as $417. Try not to purchase tickets in the morning because they tend to be around $419. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama City Tocumen Intl to Santo Domingo Las Americas flight route?

Fly from Panama City Tocumen Intl to Santo Domingo Las Americas for the best Panama City Tocumen Intl - Santo Domingo Las Americas flight prices

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from Panama City when booking 9 weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $411 when searching 9 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from Panama City for as low as $401 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Santo Domingo Las Americas flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Santo Domingo Las Americas flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Panama City to Santo Domingo flight prices changed over time?

As of June 2025, prices for Panama City to Santo Domingo flights are approximately 81% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Santo Domingo (PTY to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Santo Domingo

Best Price Found

$162

Fastest flight time

2h 31m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sat

Airports in Santo Domingo

1 airport
The best one-way flight to Santo Domingo from Panama City in the past 72 hours is $162. The best round-trip flight deal from Panama City to Santo Domingo found on momondo in the last 72 hours is $294.
The fastest flight from Panama City to Santo Domingo takes 2h 31m
Direct flights go from Panama City to Santo Domingo on Monday, Tuesday, Wednesday, Thursday, Friday and Saturday. The only airline offering direct flights is Copa Airlines.
There is 1 airport near Santo Domingo: Santo Domingo Las Americas (SDQ)

  • How far is Panama City Tocumen Intl to Santo Domingo Las Americas by plane?

    The distance between Panama City Tocumen Intl and Santo Domingo Las Americas is about 918.3 mi. By plane, this route typically takes 2h 31m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Panama City to Santo Domingo?

  • What is the most popular airline from Panama City to Santo Domingo?


Best airlines flying from Panama City to Santo Domingo

Compare and see reviews for airlines that fly from Panama City to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $288Free CancellationRating
6.7
2,345 reviews
Search Avianca flights
Copa AirlinesPriceFrom $372Free CancellationRating
7.5
1,451 reviews
Search Copa Airlines flights
  • Copa Airlines Flights From Panama City to Santo Domingo

    Copa Airlines operates around 24 flights from Panama City to Santo Domingo every week. The average price of these flights found in the last 72 hours has been $417, but momondo users have found Copa Airlines deals from Panama City to Santo Domingo from as low as $372 round-trip. Copa Airlines has been scored 7.5/10 in 1,451 reviews.


Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Santo Domingo?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Santo Domingo. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Santo Domingo with flexible booking policies on momondo?

Flights from Panama City to Santo Domingo with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Santo Domingo?

Once you have performed a search for Panama City to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.


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Tue 6/17
Tue 6/24

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