Cheap flights from Panama City to Las Vegas from $324

The month of September is, on average, the cheapest month to fly to Las Vegas from Panama City, with most prices found around $549. The month of August is another great option to travel to Las Vegas, with average flight prices from Panama City averaging around $583.

Our data shows that Thursday is the least expensive day to fly to Las Vegas. Tickets to fly out on this day can be as low as $555. Flights from Panama City to Las Vegas on a Sunday will generally be more expensive and average around $835. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Fly from Panama City Tocumen Intl to Las Vegas Harry Reid Intl for the best Panama City Tocumen Intl - Las Vegas Harry Reid Intl flight prices

You are more likely to see cheaper flights to Las Vegas from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Las Vegas for around $633 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Las Vegas from Panama City for as low as $556 on momondo.

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Las Vegas Harry Reid Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 64% on your flight if you consider stops on a Panama City to Las Vegas flight.

Copa Airlines is the most popular carrier operating from Panama City Tocumen Intl to Las Vegas Harry Reid Intl

United Airlines, Copa Airlines and American Airlines are the top three most popular airlines that fly to Las Vegas from Panama City according to our data. United Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Las Vegas. Keep in mind that there are 4 different airlines that fly to Las Vegas on a routine basis, so you have a few additional options to choose from.

Historically, on average around 1% of flights between Panama City and Las Vegas have experienced a delay on any given week. The average delay length over the past 12 months has been 220 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 1% of their flights experiencing any sort of delay.

Houston (IAH) was the most common stop: 63% of momondo users choosing 1-stop flights on this route connected there.

Flights via San Francisco (SFO) offer the lowest average round-trip price of $584.

Flights connecting via Houston (IAH) have the shortest average one-way travel time: 10h 18m.

San Francisco (SFO) has the shortest average layover time for this route: 1h 39m.

1 flights are operational daily from Panama City to Las Vegas as of March 2026. The most popular departure time for this route is 5:00PM, with 100% of flights per day taking off in the afternoon.

12 flights are operational weekly from Panama City to Las Vegas as of March 2026. The most popular departure day for this route is Sat, with 33% of flights per week taking off on this day.