Cheap flights from Panama City to Illinois from $283

The cheapest month to fly to Illinois from Panama City is in May. Flight prices, which tend to average around $201, are often lower during this time because this is during the off-season. If you aren’t able to travel to Illinois during the month of May, then flying in July is also cheap. Prices for this month can be found on momondo for an average of $210.

The cheapest day to depart from Panama City to Illinois is on a Wednesday when prices can be found for as low as $494. Flights from Panama City to Illinois on a Sunday will generally be more expensive and average around $887. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

Our most recent data shows that the best time of day to fly to Illinois is in the afternoon. Flights from Panama City to Illinois during this time can be as low as $496. Flights in the morning are often more expensive with an average ticket price of $761.

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama City Tocumen Intl - Illinois flight prices

You are more likely to see cheaper flights to Illinois from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Illinois for around $626 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Illinois from Panama City for as low as $474 on momondo.

The number of flights available between Panama City and Illinois is 2 per day as of May 2026. The most frequent departure time is 7:00PM, with 70% of daily flights leaving in the evening.

As of May 2026, 20 flights take off from Panama City and land in Illinois each week. The most common flight departure day for this route is Mon, with 25% of weekly flights taking off on this day.