Cheap flights from San Francisco to Chicago from $122

The month of September is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from San Francisco averaging around $396.

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Wednesday when prices can be found for as low as $451. This is often the case because there is less demand to fly during this day of the week. On the other hand, Monday is the most expensive day to depart from San Francisco because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $583.

Flying to Chicago O'Hare Intl Airport from San Francisco in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $472 when looking at flights departing in the afternoon. Try not to purchase tickets at noon because they tend to be around $521. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from San Francisco to Chicago O'Hare Intl for the best San Francisco - Chicago O'Hare Intl flight prices

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $434 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from San Francisco for as low as $365 on momondo.

There are 4 cabin classes available to choose from on San Francisco to Chicago O'Hare Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 20% on your flight if you consider stops on a San Francisco to Chicago O'Hare Intl Airport flight.

As of September 2026, prices for San Francisco to Chicago O'Hare Intl Airport flights are approximately 4% cheaper when compared to flights at the same time last year.

Delta and Alaska Airlines are the most popular carriers operating from San Francisco to Chicago O'Hare Intl

United Airlines, American Airlines and Alaska Airlines are the top three most popular airlines that fly to Chicago O'Hare Intl Airport from San Francisco according to our data. United Airlines is the first choice among our users, with 54% of people opting to fly with this airline when traveling to Chicago O'Hare Intl Airport. Keep in mind that there are 7 different airlines that fly to Chicago O'Hare Intl Airport on a routine basis, so you have a few additional options to choose from.

Historically, on average around 10% of flights between San Francisco and Chicago have experienced a delay on any given week. The average delay length over the past 12 months has been 188 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, United Airlines have had the least number of delays on this route over the last 12 months; with about 9% of their flights experiencing any sort of delay.

San Diego (SAN) was the most common stop: 78% of momondo users choosing 1-stop flights on this route connected there.

Flights via Denver (DEN) offer the lowest average round-trip price of $312.

Flights connecting via Las Vegas (LAS) have the shortest average one-way travel time: 6h 53m.

San Diego (SAN) has the shortest average layover time for this route: 3h 33m.

The number of flights available between San Francisco and Chicago O'Hare Intl Airport is 80 per day as of September 2026. The most frequent departure time is 8:00AM, with 41% of daily flights leaving at noon.

As of September 2026, there are 566 flights per week flying from San Francisco to Chicago O'Hare Intl Airport. The most common day of the week flights depart is Thu, with 17% of flights taking off on this day.