Cheap flights from Panama City to Buffalo from $560

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Buffalo departing on 10/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City to Buffalo (PTY-BUF)

Cheap round-trip flights

American Airlines Logo
3:15 pm - 11:04 amPTY-BUF
18h 49m2 stops
American Airlines Logo
6:23 pm - 2:03 pmBUF-PTY
20h 40m2 stops
$560American Airlines
Find Deal
Fri, Oct 17 - Fri, Oct 31
Delta Logo
2:21 pm - 11:39 pmPTY-BUF
8h 18m1 stop
Delta Logo
6:00 am - 12:56 pmBUF-PTY
7h 56m1 stop
$653Delta
Find Deal
Fri, Oct 17 - Fri, Oct 31
 Logo
3:20 am - 8:18 pmPTY-BUF
15h 58m2 stops
 Logo
2:42 pm - 7:43 pmBUF-PTY
30h 01m1 stop
Thu, Oct 16 - Fri, Oct 31
United Airlines Logo
10:00 am - 10:03 amPTY-BUF
23h 03m2 stops
United Airlines Logo
6:00 am - 1:55 pmBUF-PTY
8h 55m1 stop
$745United Airlines
Find Deal
Fri, Oct 17 - Fri, Oct 31
 Logo
3:20 am - 7:04 pmPTY-BUF
14h 44m2 stops
 Logo
10:05 am - 12:40 amBUF-PTY
15h 35m2 stops
$1,102
Find Deal
Thu, Oct 16 - Fri, Oct 31

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Panama City to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 10/17

3:15 pm-11:04 am

2 stops18h 49m

Buffalo

Fri 10/31

6:23 pm-2:03 pm

2 stops20h 40m

$560

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 10/17

2:21 pm-11:39 pm

1 stop8h 18m

Buffalo

Fri 10/31

6:00 am-12:56 pm

1 stop7h 56m

$653

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 10/16

3:20 am-8:18 pm

2 stops15h 58m

Buffalo

Fri 10/31

2:42 pm-7:43 pm

1 stop30h 01m

$695

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Fri 10/17

10:00 am-10:03 am

2 stops23h 03m

Buffalo

Fri 10/31

6:00 am-1:55 pm

1 stop8h 55m

$745

Panama CityBuffalo

PTY - BUF

PTYBUF

Panama City Tocumen Intl

Thu 10/16

3:20 am-7:04 pm

2 stops14h 44m

Buffalo

Fri 10/31

10:05 am-12:40 am

2 stops15h 35m

$1,102

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Panama City to Buffalo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Panama City to Buffalo flights?

You could potentially save up to 73% on your flight if you consider stops on a Panama City to Buffalo flight.

When to book flights from Panama City to Buffalo

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Buffalo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Buffalo (PTY to BUF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Buffalo

Direct flights

None
There are no direct flights from Panama City to Buffalo. There are no popular flight routes from Panama City to Buffalo.
  • How far is Panama City Tocumen Intl to Buffalo by plane?

    Buffalo is 2341.1 mi away from Panama City Tocumen Intl. Flights usually cover this in 8h 18m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Buffalo Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Buffalo Airport refresh daily.

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Buffalo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Buffalo Airport.

  • What documentation or ID do you need to fly to Buffalo Airport?

    The required travel and health documents for your Buffalo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Buffalo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Batavia
Cheektowaga
Tonawanda
Williamsville
Amherst
Grand Island
Lockport
Orchard Park
West Seneca
East Aurora
Eden
Angola
Bowmansville

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Buffalo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Buffalo for you.

Can I find flights from Panama City to Buffalo with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Buffalo flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Buffalo?

momondo helps you find the best flight between Panama City and Buffalo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Panama City to Buffalo right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Buffalo from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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1 adult
Tue 9/2
Tue 9/9

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