What is the cheapest airline that flies from Panama City NW Florida Beaches to Missouri?

Delta, Southwest, and American Airlines are the most popular carriers operating from Panama City NW Florida Beaches to Missouri

What airlines fly to Missouri?

Delta, Southwest and American Airlines are the top three most popular airlines that fly to Missouri from Panama City, Florida according to our data. Delta is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 6 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Missouri?

Prices for flights from Panama City NW Florida Beaches Airport to Missouri are updated daily.

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Missouri?

There are 3 operators available for flights from Panama City NW Florida Beaches Airport to Missouri as of March 2026.

How old do you have to be to fly from Panama City NW Florida Beaches Airport to Missouri?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Missouri.

What documentation or ID do you need to fly to Missouri?

The required travel and health documents for your Missouri trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Missouri. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$101 Cheap Flights from Panama City to Missouri in 2026

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Find the cheapest flights from Panama City, Florida to Missouri

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:57 pm - 10:28 pm

ECP

STL

5h 31m

1 stop

4:49 pm - 9:59 pm

STL

ECP

5h 10m

1 stop

$241United Airlines

Thu, Apr 9 - Mon, Apr 13

4:57 pm - 10:28 pm

ECP

STL

5h 31m

1 stop

9:10 am - 9:59 pm

STL

ECP

12h 49m

2 stops

$246United Airlines

Thu, Apr 9 - Mon, Apr 13

6:40 am - 12:50 pm

ECP

STL

6h 10m

1 stop

3:00 pm - 9:30 pm

STL

ECP

6h 30m

1 stop

$255Southwest

Mon, May 4 - Fri, May 8

6:00 am - 12:20 pm

ECP

MCI

6h 20m

1 stop

5:12 pm - 11:12 pm

MCI

ECP

6h 00m

1 stop

$267Delta

Wed, Apr 8 - Wed, Apr 15

4:57 pm - 10:30 pm

ECP

MCI

5h 33m

1 stop

1:05 pm - 9:59 pm

MCI

ECP

8h 54m

2 stops

$272United Airlines

Wed, Apr 8 - Wed, Apr 15

2:50 pm - 12:15 am

ECP

MCI

9h 25m

1 stop

5:15 am - 11:45 am

MCI

ECP

6h 30m

1 stop

$280Southwest

Sat, Mar 28 - Sat, Apr 4

1:02 pm - 7:27 pm

ECP

MCI

6h 25m

1 stop

6:33 pm - 11:49 pm

MCI

ECP

5h 16m

1 stop

$281American Airlines

Sat, Mar 14 - Wed, Mar 18

5:49 am - 10:34 am

ECP

STL

4h 45m

1 stop

7:25 am - 12:41 pm

STL

ECP

5h 16m

1 stop

$289Delta

Fri, May 1 - Sun, May 3

1:20 pm - 5:53 pm

ECP

STL

4h 33m

1 stop

9:21 am - 2:24 pm

STL

ECP

5h 03m

1 stop

$291American Airlines

Fri, Mar 13 - Tue, Mar 17

7:10 am - 2:55 pm

ECP

STL

7h 45m

2 stops

5:55 am - 11:15 am

STL

ECP

5h 20m

1 stop

$294Southwest

Fri, May 1 - Sun, May 3

Southwest flights from Panama City, Florida to Missouri

Our best Southwest deals on Panama City, Florida to Missouri flight tickets

Southwest

May 4

ECP6:40 amPanama City NW Florida Beaches

6h 10m

1 stop

STL12:50 pmLambert-St Louis

May 8

STL3:00 pmLambert-St Louis

6h 30m

1 stop

ECP9:30 pmPanama City NW Florida Beaches

$255

Southwest

Mar 28

ECP2:50 pmPanama City NW Florida Beaches

9h 25m

1 stop

MCI12:15 amKansas City

Apr 4

MCI5:15 amKansas City

6h 30m

1 stop

ECP11:45 amPanama City NW Florida Beaches

$280

Southwest

May 1

ECP7:10 amPanama City NW Florida Beaches

7h 45m

2 stops

STL2:55 pmLambert-St Louis

May 3

STL5:55 amLambert-St Louis

5h 20m

1 stop

ECP11:15 amPanama City NW Florida Beaches

$294

Delta flights from Panama City, Florida to Missouri

Our best Delta deals on Panama City, Florida to Missouri flight tickets

Delta

Apr 8

ECP6:00 amPanama City NW Florida Beaches

6h 20m

1 stop

MCI12:20 pmKansas City

Apr 15

MCI5:12 pmKansas City

6h 00m

1 stop

ECP11:12 pmPanama City NW Florida Beaches

$267

Delta

May 1

ECP5:49 amPanama City NW Florida Beaches

4h 45m

1 stop

STL10:34 amLambert-St Louis

May 3

STL7:25 amLambert-St Louis

5h 16m

1 stop

ECP12:41 pmPanama City NW Florida Beaches

$289

Delta

Mar 14

ECP5:30 pmPanama City NW Florida Beaches

6h 28m

1 stop

STL11:58 pmLambert-St Louis

Mar 17

STL6:59 pmLambert-St Louis

4h 05m

1 stop

ECP11:04 pmPanama City NW Florida Beaches

$303

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Thu 4/9

4:57 pm-10:28 pm

1 stop5h 31m

Lambert-St Louis

Mon 4/13

4:49 pm-9:59 pm

1 stop5h 10m

$241

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Thu 4/9

4:57 pm-10:28 pm

1 stop5h 31m

Lambert-St Louis

Mon 4/13

9:10 am-9:59 pm

2 stops12h 49m

$246

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Mon 5/4

6:40 am-12:50 pm

1 stop6h 10m

Lambert-St Louis

Fri 5/8

3:00 pm-9:30 pm

1 stop6h 30m

$255

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Wed 4/8

6:00 am-12:20 pm

1 stop6h 20m

Kansas City

Wed 4/15

5:12 pm-11:12 pm

1 stop6h 00m

$267

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Wed 4/8

4:57 pm-10:30 pm

1 stop5h 33m

Kansas City

Wed 4/15

1:05 pm-9:59 pm

2 stops8h 54m

$272

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Sat 3/28

2:50 pm-12:15 am

1 stop9h 25m

Kansas City

Sat 4/4

5:15 am-11:45 am

1 stop6h 30m

$280

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Sat 3/14

1:02 pm-7:27 pm

1 stop6h 25m

Kansas City

Wed 3/18

6:33 pm-11:49 pm

1 stop5h 16m

$281

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 5/1

5:49 am-10:34 am

1 stop4h 45m

Lambert-St Louis

Sun 5/3

7:25 am-12:41 pm

1 stop5h 16m

$289

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 3/13

1:20 pm-5:53 pm

1 stop4h 33m

Lambert-St Louis

Tue 3/17

9:21 am-2:24 pm

1 stop5h 03m

$291

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 5/1

7:10 am-2:55 pm

2 stops7h 45m

Lambert-St Louis

Sun 5/3

5:55 am-11:15 am

1 stop5h 20m

$294

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City, Florida to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Missouri?

In general, October is the cheapest month to fly from Panama City, Florida to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $198. If you aren’t able to travel to Missouri during the month of October, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $246.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Panama City, Florida to Missouri is on a Tuesday when prices can be found for as low as $345. Flights from Panama City, Florida to Missouri on a Saturday will generally be more expensive and average around $529. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest Panama City NW Florida Beaches to Missouri flight route?

Fly from Panama City NW Florida Beaches to Lambert-St Louis for the best Panama City NW Florida Beaches - Missouri flight prices

What cabin class options are available on Panama City NW Florida Beaches to Missouri flights?

There is only 1 cabin class available to choose from on Panama City NW Florida Beaches to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City, Florida to Missouri flights?

You could potentially save up to 31% on your flight if you consider stops on a Panama City, Florida to Missouri flight.

Cheap Panama City, Florida to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Missouri

Best Price Found	$167
Fastest flight time	1h 50m
Direct flights	Every day
Airports in Missouri	55 airports

The best one-way flight to Missouri from Panama City, Florida in the past 72 hours is $167. The best round-trip flight deal from Panama City, Florida to Missouri found on momondo in the last 72 hours is $450.

The fastest flight from Panama City, Florida to Missouri takes 1h 50m

Direct flights go from Panama City, Florida to Missouri every day.

There are 55 airports in Missouri. From Panama City, Florida there are direct flights to Kansas City (MCI), Lambert-St Louis (STL).

Search flight deals

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Missouri?
Prices for flights from Panama City NW Florida Beaches Airport to Missouri are updated daily.
How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Missouri?
There are 3 operators available for flights from Panama City NW Florida Beaches Airport to Missouri as of March 2026.
How old do you have to be to fly from Panama City NW Florida Beaches Airport to Missouri?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Missouri.
What documentation or ID do you need to fly to Missouri?
The required travel and health documents for your Missouri trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Missouri. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Panama City, Florida to Missouri?
Based on momondo bookings for flights between Panama City, Florida and Missouri, the leading plane model is Embraer 175 (Enhanced Winglets), making up 11.54% of the total bookings. Other popular models include Boeing 737-800 with 11.54%, Canadair (Bombardier) Regional Jet 900 with 11.54%, and Boeing 737-800 Passenger/BBJ2 (winglets) with 11.54%.

Best airlines flying from Panama City, Florida to Missouri

Compare and see reviews for airlines that fly from Panama City, Florida to Missouri with momondo

Airline	Rating	Free Cancellation	Price
Southwest	PriceFrom $157	Free Cancellation	Rating 8.0 4,306 reviews	Search Southwest flights
Delta	PriceFrom $176	Free Cancellation	Rating 7.9 8,237 reviews	Search Delta flights
American Airlines	PriceFrom $269	Free Cancellation	Rating 7.1 11,369 reviews	Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Missouri?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Missouri. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Missouri with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Missouri flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Missouri?

momondo provides multiple filters to help you find the best flight to Missouri from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Missouri right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.