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Cheap flights from Panama City, Florida to Missouri from $104

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Missouri departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to Missouri

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 10:45 amECP-STL
4h 45m1 stop
Delta Logo
7:02 pm - 11:06 pmSTL-ECP
4h 04m1 stop
$207Delta
Find Deal
Fri, Dec 5 - Sun, Dec 7
Southwest Logo
7:15 am - 11:25 amECP-STL
4h 10m1 stop
Southwest Logo
10:00 am - 5:35 pmSTL-ECP
7h 35m2 stops
$212Southwest
Find Deal
Fri, Dec 5 - Sun, Dec 7
Southwest Logo
10:00 am - 5:25 pmECP-STL
7h 25m2 stops
Southwest Logo
10:00 am - 5:35 pmSTL-ECP
7h 35m2 stops
$217Southwest
Find Deal
Fri, Dec 5 - Sun, Dec 7
Delta Logo
6:59 pm - 11:42 pmECP-STL
4h 43m1 stop
Delta Logo
6:00 am - 12:47 pmSTL-ECP
6h 47m1 stop
$248Delta
Find Deal
Fri, Dec 12 - Thu, Dec 18
American Airlines Logo
12:08 pm - 8:38 pmECP-STL
8h 30m2 stops
American Airlines Logo
5:15 am - 2:13 pmSTL-ECP
8h 58m2 stops
$272American Airlines
Find Deal
Fri, Dec 5 - Sun, Dec 7
Delta Logo
7:30 am - 12:57 pmECP-STL
5h 27m1 stop
Delta Logo
6:00 am - 10:17 amSTL-ECP
4h 17m1 stop
$273Delta
Find Deal
Wed, Dec 10 - Sun, Dec 21
Southwest Logo
10:00 am - 5:25 pmECP-STL
7h 25m2 stops
Southwest Logo
5:25 am - 12:50 pmSTL-ECP
7h 25m1 stop
$278Southwest
Find Deal
Thu, Dec 11 - Mon, Dec 22
American Airlines Logo
12:08 pm - 10:47 pmECP-STL
10h 39m2 stops
American Airlines Logo
5:02 am - 10:41 amSTL-ECP
5h 39m1 stop
$282American Airlines
Find Deal
Fri, Dec 5 - Sun, Dec 7
United Airlines Logo
3:10 pm - 9:28 pmECP-SGF
6h 18m1 stop
United Airlines Logo
6:35 am - 12:37 pmSGF-ECP
6h 02m1 stop
$328United Airlines
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Thu, Apr 16 - Sun, Apr 19
United Airlines Logo
10:04 am - 3:50 pmECP-STL
5h 46m1 stop
United Airlines Logo
6:15 am - 1:57 pmSTL-ECP
7h 42m1 stop
$359United Airlines
Find Deal
Sat, Nov 22 - Fri, Nov 28

Delta flights from Panama City, Florida to Missouri

Our best Delta deals on Panama City, Florida to Missouri flight tickets
Delta
Dec 5
ECP6:00 amPanama City NW Florida Beaches
4h 45m
1 stop
STL10:45 amLambert-St Louis
Dec 7
STL7:02 pmLambert-St Louis
4h 04m
1 stop
ECP11:06 pmPanama City NW Florida Beaches
$207
Find similar
Delta
Dec 12
ECP6:59 pmPanama City NW Florida Beaches
4h 43m
1 stop
STL11:42 pmLambert-St Louis
Dec 18
STL6:00 amLambert-St Louis
6h 47m
1 stop
ECP12:47 pmPanama City NW Florida Beaches
$248
Find similar
Delta
Dec 10
ECP7:30 amPanama City NW Florida Beaches
5h 27m
1 stop
STL12:57 pmLambert-St Louis
Dec 21
STL6:00 amLambert-St Louis
4h 17m
1 stop
ECP10:17 amPanama City NW Florida Beaches
$273
Find similar

Southwest flights from Panama City, Florida to Missouri

Our best Southwest deals on Panama City, Florida to Missouri flight tickets
Southwest
Dec 5
ECP7:15 amPanama City NW Florida Beaches
4h 10m
1 stop
STL11:25 amLambert-St Louis
Dec 7
STL10:00 amLambert-St Louis
7h 35m
2 stops
ECP5:35 pmPanama City NW Florida Beaches
$212
Find similar
Southwest
Dec 5
ECP10:00 amPanama City NW Florida Beaches
7h 25m
2 stops
STL5:25 pmLambert-St Louis
Dec 7
STL10:00 amLambert-St Louis
7h 35m
2 stops
ECP5:35 pmPanama City NW Florida Beaches
$217
Find similar
Southwest
Dec 11
ECP10:00 amPanama City NW Florida Beaches
7h 25m
2 stops
STL5:25 pmLambert-St Louis
Dec 22
STL5:25 amLambert-St Louis
7h 25m
1 stop
ECP12:50 pmPanama City NW Florida Beaches
$278
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 12/5

6:00 am-10:45 am

1 stop4h 45m

Lambert-St Louis

Sun 12/7

7:02 pm-11:06 pm

1 stop4h 04m

$207

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 12/5

7:15 am-11:25 am

1 stop4h 10m

Lambert-St Louis

Sun 12/7

10:00 am-5:35 pm

2 stops7h 35m

$212

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 12/5

10:00 am-5:25 pm

2 stops7h 25m

Lambert-St Louis

Sun 12/7

10:00 am-5:35 pm

2 stops7h 35m

$217

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 12/12

6:59 pm-11:42 pm

1 stop4h 43m

Lambert-St Louis

Thu 12/18

6:00 am-12:47 pm

1 stop6h 47m

$248

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 12/5

12:08 pm-8:38 pm

2 stops8h 30m

Lambert-St Louis

Sun 12/7

5:15 am-2:13 pm

2 stops8h 58m

$272

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Wed 12/10

7:30 am-12:57 pm

1 stop5h 27m

Lambert-St Louis

Sun 12/21

6:00 am-10:17 am

1 stop4h 17m

$273

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Thu 12/11

10:00 am-5:25 pm

2 stops7h 25m

Lambert-St Louis

Mon 12/22

5:25 am-12:50 pm

1 stop7h 25m

$278

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 12/5

12:08 pm-10:47 pm

2 stops10h 39m

Lambert-St Louis

Sun 12/7

5:02 am-10:41 am

1 stop5h 39m

$282

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

Thu 4/16

3:10 pm-9:28 pm

1 stop6h 18m

Springfield-Branson

Sun 4/19

6:35 am-12:37 pm

1 stop6h 02m

$328

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Sat 11/22

10:04 am-3:50 pm

1 stop5h 46m

Lambert-St Louis

Fri 11/28

6:15 am-1:57 pm

1 stop7h 42m

$359

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Missouri from

How to get the cheapest flight ticket from Panama City, Florida to Missouri

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Missouri?

In general, October is the cheapest month to fly from Panama City, Florida to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $243. If you aren’t able to travel to Missouri during the month of October, then flying in August is also cheap. Prices for this month can be found on momondo for an average of $246.

What is the cheapest day to depart on your flight to Missouri?

The cheapest day to depart from Panama City, Florida to Missouri is on a Wednesday when prices can be found for as low as $374. Flights from Panama City, Florida to Missouri on a Saturday will generally be more expensive and average around $503. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest Panama City NW Florida Beaches to Missouri flight route?

Fly from Panama City NW Florida Beaches to Lambert-St Louis for the best Panama City NW Florida Beaches - Missouri flight prices

What cabin class options are available on Panama City NW Florida Beaches to Missouri flights?

There is only 1 cabin class available to choose from on Panama City NW Florida Beaches to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City, Florida to Missouri flights?

No. A direct flight is the cheapest option for a flight between Panama City, Florida to Missouri.

Cheap Panama City, Florida to Missouri flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Missouri

Best Price Found

$214

Fastest flight time

1h 55m

Direct flights

Mon, Tue, Wed, Fri, Sat and Sun

Airports in Missouri

2 airports
The best one-way flight to Missouri from Panama City, Florida in the past 72 hours is $214. The best round-trip flight deal from Panama City, Florida to Missouri found on momondo in the last 72 hours is $503.
The fastest flight from Panama City, Florida to Missouri takes 1h 55m
Direct flights go from Panama City, Florida to Missouri on Monday, Tuesday, Wednesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There are 2 airports near Missouri: Kansas City (MCI), Lambert-St Louis (STL)
Search flight deals

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Missouri?

    Prices for flights from Panama City NW Florida Beaches Airport to Missouri are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Missouri?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Missouri?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Missouri.

  • What documentation or ID do you need to fly to Missouri?

    The required travel and health documents for your Missouri trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Missouri. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Panama City, Florida to Missouri?

Best airlines flying from Panama City, Florida to Missouri

Compare and see reviews for airlines that fly from Panama City, Florida to Missouri with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $157Free CancellationRating
8.0
4,241 reviews
Search Southwest flights
American AirlinesPriceFrom $158Free CancellationRating
7.2
11,033 reviews
Search American Airlines flights
DeltaPriceFrom $176Free CancellationRating
7.9
7,997 reviews
Search Delta flights
United AirlinesPriceFrom $401Free CancellationRating
7.4
8,994 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Missouri?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Missouri. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Missouri with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Missouri flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Missouri?

momondo provides multiple filters to help you find the best flight to Missouri from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Missouri right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Missouri flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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