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Cheap flights from Panama City, Florida to Chicago from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Chicago departing on 3/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
4:45 pm - 10:22 pm
ECP
-
MDW
5h 37m1 stop
Delta Logo
10:46 am - 5:12 pm
MDW
-
ECP
6h 26m1 stop
$229Delta
Sat, Jan 24 - Mon, Jan 26
Southwest Logo
4:30 pm - 10:30 pm
ECP
-
MDW
6h 00m1 stop
Southwest Logo
6:15 am - 2:55 pm
MDW
-
ECP
8h 40m2 stops
$234Southwest
Sun, Jan 25 - Tue, Jan 27
Delta Logo
10:01 am - 4:29 pm
ECP
-
MDW
6h 28m1 stop
Delta Logo
6:00 am - 11:08 am
MDW
-
ECP
5h 08m1 stop
$249Delta
Thu, Jan 15 - Thu, Jan 22
Delta Logo
6:00 am - 10:32 am
ECP
-
MDW
4h 32m1 stop
Delta Logo
5:31 pm - 10:51 pm
MDW
-
ECP
5h 20m1 stop
$269Delta
Sat, Jan 10 - Wed, Jan 14
Southwest Logo
10:10 am - 6:10 pm
ECP
-
MDW
8h 00m2 stops
Southwest Logo
2:35 pm - 6:10 pm
MDW
-
ECP
3h 35m1 stop
$289Southwest
Thu, Jan 15 - Sun, Jan 18
Southwest Logo
10:10 am - 6:10 pm
ECP
-
MDW
8h 00m2 stops
Southwest Logo
10:10 am - 6:10 pm
MDW
-
ECP
8h 00m2 stops
$294Southwest
Sun, Jan 25 - Tue, Jan 27
Southwest Logo
7:20 am - 11:55 am
ECP
-
MDW
4h 35m1 stop
Southwest Logo
5:05 am - 12:50 pm
MDW
-
ECP
7h 45m1 stop
$304Southwest
Thu, Mar 19 - Fri, Mar 20
Southwest Logo
1:55 pm - 4:15 pm
ECP
-
MDW
2h 20mnonstop
Southwest Logo
3:05 pm - 5:20 pm
MDW
-
ECP
2h 15mnonstop
$319Southwest
Thu, Mar 19 - Fri, Mar 20
Delta Logo
6:00 am - 10:27 am
ECP
-
MDW
4h 27m1 stop
Delta Logo
11:21 am - 3:46 pm
MDW
-
ECP
4h 25m1 stop
$334Delta
Sun, Jan 11 - Thu, Jan 15
Delta Logo
6:00 am - 10:27 am
ECP
-
MDW
4h 27m1 stop
Delta Logo
5:31 pm - 10:51 pm
MDW
-
ECP
5h 20m1 stop
$339Delta
Tue, Jan 6 - Wed, Jan 7

Southwest flights from Panama City, Florida to Chicago Midway Airport

Our best Southwest deals on Panama City, Florida to Chicago Midway Airport flight tickets
Southwest
Jan 25
ECP4:30 pmPanama City NW Florida Beaches
6h 00m
1 stop
MDW10:30 pmChicago Midway
Jan 27
MDW6:15 amChicago Midway
8h 40m
2 stops
ECP2:55 pmPanama City NW Florida Beaches
$234
Find similar
Southwest
Jan 15
ECP10:10 amPanama City NW Florida Beaches
8h 00m
2 stops
MDW6:10 pmChicago Midway
Jan 18
MDW2:35 pmChicago Midway
3h 35m
1 stop
ECP6:10 pmPanama City NW Florida Beaches
$289
Find similar
Southwest
Jan 25
ECP10:10 amPanama City NW Florida Beaches
8h 00m
2 stops
MDW6:10 pmChicago Midway
Jan 27
MDW10:10 amChicago Midway
8h 00m
2 stops
ECP6:10 pmPanama City NW Florida Beaches
$294
Find similar

Delta flights from Panama City, Florida to Chicago Midway Airport

Our best Delta deals on Panama City, Florida to Chicago Midway Airport flight tickets
Delta
Jan 24
ECP4:45 pmPanama City NW Florida Beaches
5h 37m
1 stop
MDW10:22 pmChicago Midway
Jan 26
MDW10:46 amChicago Midway
6h 26m
1 stop
ECP5:12 pmPanama City NW Florida Beaches
$229
Find similar
Delta
Jan 15
ECP10:01 amPanama City NW Florida Beaches
6h 28m
1 stop
MDW4:29 pmChicago Midway
Jan 22
MDW6:00 amChicago Midway
5h 08m
1 stop
ECP11:08 amPanama City NW Florida Beaches
$249
Find similar
Delta
Jan 10
ECP6:00 amPanama City NW Florida Beaches
4h 32m
1 stop
MDW10:32 amChicago Midway
Jan 14
MDW5:31 pmChicago Midway
5h 20m
1 stop
ECP10:51 pmPanama City NW Florida Beaches
$269
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sat 1/24

4:45 pm-10:22 pm

1 stop5h 37m

Chicago Midway

Mon 1/26

10:46 am-5:12 pm

1 stop6h 26m

$229

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sun 1/25

4:30 pm-10:30 pm

1 stop6h 00m

Chicago Midway

Tue 1/27

6:15 am-2:55 pm

2 stops8h 40m

$234

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Thu 1/15

10:01 am-4:29 pm

1 stop6h 28m

Chicago Midway

Thu 1/22

6:00 am-11:08 am

1 stop5h 08m

$249

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sat 1/10

6:00 am-10:32 am

1 stop4h 32m

Chicago Midway

Wed 1/14

5:31 pm-10:51 pm

1 stop5h 20m

$269

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Thu 1/15

10:10 am-6:10 pm

2 stops8h 00m

Chicago Midway

Sun 1/18

2:35 pm-6:10 pm

1 stop3h 35m

$289

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sun 1/25

10:10 am-6:10 pm

2 stops8h 00m

Chicago Midway

Tue 1/27

10:10 am-6:10 pm

2 stops8h 00m

$294

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Thu 3/19

7:20 am-11:55 am

1 stop4h 35m

Chicago Midway

Fri 3/20

5:05 am-12:50 pm

1 stop7h 45m

$304

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Thu 3/19

1:55 pm-4:15 pm

Nonstop2h 20m

Chicago Midway

Fri 3/20

3:05 pm-5:20 pm

Nonstop2h 15m

$319

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sun 1/11

6:00 am-10:27 am

1 stop4h 27m

Chicago Midway

Thu 1/15

11:21 am-3:46 pm

1 stop4h 25m

$334

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Tue 1/6

6:00 am-10:27 am

1 stop4h 27m

Chicago Midway

Wed 1/7

5:31 pm-10:51 pm

1 stop5h 20m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Panama City, Florida to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago Midway Airport?

The month of June is, on average, the cheapest month to fly to Chicago Midway Airport from Panama City, Florida, with most prices found around $188. If you are unable to visit Chicago Midway Airport during the month of June, then departing from Panama City, Florida during the month December is also very affordable. Most momondo users find prices during this month for around $236.

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Saturday is the cheapest day to fly to Chicago Midway Airport from Panama City, Florida. The lowest ticket price found for a Saturday departure recently was $372. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Monday is the most expensive day to depart from Panama City, Florida because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $443.

What is the cheapest Panama City NW Florida Beaches to Chicago Midway flight route?

Fly from Panama City NW Florida Beaches to Chicago Midway for the best Panama City NW Florida Beaches - Chicago Midway flight prices

What cabin class options are available on Panama City NW Florida Beaches to Chicago Midway flights?

There is only 1 cabin class available to choose from on Panama City NW Florida Beaches to Chicago Midway flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

When to book flights from Panama City, Florida to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Chicago Midway Airport (ECP to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Chicago Midway Airport

Fastest flight time

2h 20m

Direct flights

Thu, Fri and Sat
The fastest flight from Panama City, Florida to Chicago Midway Airport takes 2h 20m
Direct flights go from Panama City, Florida to Chicago Midway Airport on Thursday, Friday and Saturday. There are no airlines offering direct flights.
Search flight deals

  • How far is Panama City NW Florida Beaches to Chicago Midway by plane?

    The straight-line distance from Panama City NW Florida Beaches to Chicago Midway is 811.2 mi. In terms of flight time, this usually takes a little over 2h 20m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Chicago Midway Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Chicago Midway Airport refresh daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Chicago Midway Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Chicago Midway Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The travel and health documents you'll need for your trip to Chicago Midway Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago Midway Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City, Florida to Chicago Midway Airport?

  • What is the most popular airline from Panama City, Florida to Chicago Midway Airport?

Best airlines flying from Panama City, Florida to Chicago Midway Airport

Compare and see reviews for airlines that fly from Panama City, Florida to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $229Free CancellationRating
8.0
4,256 reviews
Search Southwest flights
DeltaPriceFrom $236Free CancellationRating
7.9
8,019 reviews
Search Delta flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Portage
Lansing
Valparaiso
Schererville
Munster
Crown Point
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Chicago from Panama City.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

Flights from Panama City to Chicago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Chicago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Chicago from Panama City.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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