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Cheap flights from Panama City, Florida to Chicago from $146

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Chicago departing on 4/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Panama City, Florida to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
11:50 am - 5:50 pm
ECP
-
MDW
6h 00m
1 stop
Southwest Logo
8:00 am - 10:10 am
MDW
-
ECP
2h 10mnonstop
$281Southwest
Sat, Apr 25 - Sat, May 2
Southwest Logo
1:30 pm - 10:45 pm
ECP
-
MDW
9h 15m
2 stops
Southwest Logo
8:00 am - 10:10 am
MDW
-
ECP
2h 10mnonstop
$286Southwest
Sat, Apr 25 - Sat, May 2
Southwest Logo
1:30 pm - 8:05 pm
ECP
-
MDW
6h 35m
2 stops
Southwest Logo
10:30 am - 4:15 pm
MDW
-
ECP
5h 45m
1 stop
$296Southwest
Sat, Apr 25 - Sat, May 2
Southwest Logo
11:50 am - 9:05 pm
ECP
-
MDW
9h 15m
2 stops
Southwest Logo
12:45 pm - 8:25 pm
MDW
-
ECP
7h 40m
2 stops
$301Southwest
Sat, Apr 25 - Sat, May 2
Southwest Logo
6:25 pm - 10:15 pm
ECP
-
MDW
3h 50m
1 stop
Southwest Logo
8:00 am - 6:00 pm
MDW
-
ECP
10h 00m
2 stops
$302Southwest
Wed, Jun 3 - Sat, Jun 6
Southwest Logo
7:15 am - 2:55 pm
ECP
-
MDW
7h 40m
2 stops
Southwest Logo
8:00 am - 6:00 pm
MDW
-
ECP
10h 00m
2 stops
$307Southwest
Wed, Jun 3 - Sat, Jun 6
Southwest Logo
3:05 pm - 5:25 pm
ECP
-
MDW
2h 20mnonstop
Southwest Logo
8:00 am - 10:10 am
MDW
-
ECP
2h 10mnonstop
$341Southwest
Sat, Apr 25 - Sat, May 2
Delta Logo
2:50 pm - 9:09 pm
ECP
-
MDW
6h 19m
1 stop
Delta Logo
5:30 pm - 10:51 pm
MDW
-
ECP
5h 21m
1 stop
$345Delta
Wed, Jun 3 - Sat, Jun 6
Delta Logo
6:00 am - 11:56 am
ECP
-
MDW
5h 56m
1 stop
Delta Logo
6:23 am - 12:50 pm
MDW
-
ECP
6h 27m
1 stop
$353Delta
Fri, May 8 - Mon, May 11
Southwest Logo
12:05 pm - 4:45 pm
ECP
-
MDW
4h 40m
1 stop
Southwest Logo
11:15 am - 1:25 pm
MDW
-
ECP
2h 10mnonstop
$364Southwest
Wed, May 6 - Sun, May 10

Southwest flights from Panama City, Florida to Chicago Midway Airport

Our best Southwest deals on Panama City, Florida to Chicago Midway Airport flight tickets
Southwest
Apr 25
ECP11:50 amPanama City NW Florida Beaches
6h 00m
1 stop
MDW5:50 pmChicago Midway
May 2
MDW8:00 amChicago Midway
2h 10m
ECP10:10 amPanama City NW Florida Beaches
$281
Southwest
Apr 25
ECP1:30 pmPanama City NW Florida Beaches
9h 15m
2 stops
MDW10:45 pmChicago Midway
May 2
MDW8:00 amChicago Midway
2h 10m
ECP10:10 amPanama City NW Florida Beaches
$286
Southwest
Apr 25
ECP1:30 pmPanama City NW Florida Beaches
6h 35m
2 stops
MDW8:05 pmChicago Midway
May 2
MDW10:30 amChicago Midway
5h 45m
1 stop
ECP4:15 pmPanama City NW Florida Beaches
$296

Delta flights from Panama City, Florida to Chicago Midway Airport

Our best Delta deals on Panama City, Florida to Chicago Midway Airport flight tickets
Delta
Jun 3
ECP2:50 pmPanama City NW Florida Beaches
6h 19m
1 stop
MDW9:09 pmChicago Midway
Jun 6
MDW5:30 pmChicago Midway
5h 21m
1 stop
ECP10:51 pmPanama City NW Florida Beaches
$345
Delta
May 8
ECP6:00 amPanama City NW Florida Beaches
5h 56m
1 stop
MDW11:56 amChicago Midway
May 11
MDW6:23 amChicago Midway
6h 27m
1 stop
ECP12:50 pmPanama City NW Florida Beaches
$353
Delta
Jun 9
ECP9:19 amPanama City NW Florida Beaches
6h 57m
1 stop
MDW4:16 pmChicago Midway
Jun 24
MDW6:05 amChicago Midway
4h 45m
1 stop
ECP10:50 amPanama City NW Florida Beaches
$374

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sat 4/25

11:50 am-5:50 pm

1 stop6h 00m

Chicago Midway

Sat 5/2

8:00 am-10:10 am

Nonstop2h 10m

$281

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sat 4/25

1:30 pm-10:45 pm

2 stops9h 15m

Chicago Midway

Sat 5/2

8:00 am-10:10 am

Nonstop2h 10m

$286

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sat 4/25

1:30 pm-8:05 pm

2 stops6h 35m

Chicago Midway

Sat 5/2

10:30 am-4:15 pm

1 stop5h 45m

$296

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sat 4/25

11:50 am-9:05 pm

2 stops9h 15m

Chicago Midway

Sat 5/2

12:45 pm-8:25 pm

2 stops7h 40m

$301

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Wed 6/3

6:25 pm-10:15 pm

1 stop3h 50m

Chicago Midway

Sat 6/6

8:00 am-6:00 pm

2 stops10h 00m

$302

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Wed 6/3

7:15 am-2:55 pm

2 stops7h 40m

Chicago Midway

Sat 6/6

8:00 am-6:00 pm

2 stops10h 00m

$307
Quickest round-trip

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sat 4/25

3:05 pm-5:25 pm

Nonstop2h 20m

Chicago Midway

Sat 5/2

8:00 am-10:10 am

Nonstop2h 10m

$341

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Wed 6/3

2:50 pm-9:09 pm

1 stop6h 19m

Chicago Midway

Sat 6/6

5:30 pm-10:51 pm

1 stop5h 21m

$345

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Fri 5/8

6:00 am-11:56 am

1 stop5h 56m

Chicago Midway

Mon 5/11

6:23 am-12:50 pm

1 stop6h 27m

$353

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Wed 5/6

12:05 pm-4:45 pm

1 stop4h 40m

Chicago Midway

Sun 5/10

11:15 am-1:25 pm

Nonstop2h 10m

$364

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Panama City, Florida to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City, Florida and Chicago Midway Airport?

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Thursday is the cheapest day to fly to Chicago Midway Airport from Panama City, Florida. The lowest ticket price found for a Thursday departure recently was $376. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Monday is the most expensive day to depart from Panama City, Florida because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $437.

What is the cheapest Panama City NW Florida Beaches to Chicago Midway flight route?

Fly from Panama City NW Florida Beaches to Chicago Midway for the best Panama City NW Florida Beaches - Chicago Midway flight prices

What cabin class options are available on Panama City NW Florida Beaches to Chicago Midway flights?

There is only 1 cabin class available to choose from on Panama City NW Florida Beaches to Chicago Midway flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City, Florida to Chicago Midway Airport flights?

No. A direct flight is the cheapest option for a flight between Panama City, Florida to Chicago Midway Airport.

When to book flights from Panama City, Florida to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Chicago Midway Airport (ECP to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Chicago Midway Airport

Best Price Found

$243

Fastest flight time

2h 15m

Direct flights

Mon, Tue, Fri, Sat and Sun
The best one-way flight to Chicago Midway Airport from Panama City, Florida in the past 72 hours is $243. The best round-trip flight deal from Panama City, Florida to Chicago Midway Airport found on momondo in the last 72 hours is $366.
The fastest flight from Panama City, Florida to Chicago Midway Airport takes 2h 15m
Direct flights go from Panama City, Florida to Chicago Midway Airport on Monday, Tuesday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
Search flight deals

  • How far is Panama City NW Florida Beaches to Chicago Midway by plane?

    The straight-line distance from Panama City NW Florida Beaches to Chicago Midway is 811.2 mi. In terms of flight time, this usually takes a little over 2h 15m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Chicago Midway Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Chicago Midway Airport refresh daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Chicago Midway Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Chicago Midway Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The travel and health documents you'll need for your trip to Chicago Midway Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago Midway Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Panama City, Florida to Chicago Midway Airport?

  • What is the most popular airline from Panama City, Florida to Chicago Midway Airport?

Best airlines flying from Panama City, Florida to Chicago Midway Airport

Compare and see reviews for airlines that fly from Panama City, Florida to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $236Free CancellationRating
7.9
8,358 reviews
Search Delta flights
SouthwestPriceFrom $236Free CancellationRating
8.0
4,329 reviews
Search Southwest flights

  • Southwest Flights From Panama City, Florida to Chicago Midway Airport

    The lowest priced Southwest flight from Panama City, Florida to Chicago Midway Airport from the last 72 hours was $236. Generally, Southwest has 6 flights on this route every week with an average price of $386. Southwest is rated 8.0/10 by our users.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Saint Joseph
Benton Harbor
Portage
Lansing
Valparaiso
Schererville
Munster
Crown Point
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Chicago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Chicago from Panama City.

Can I find flights from Panama City to Chicago with flexible booking policies on momondo?

Flights from Panama City to Chicago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Chicago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Chicago from Panama City.

I’m not ready to book a flight from Panama City to Chicago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Panama City to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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