What airlines fly to Florida Keys?

Delta, American Airlines and Silver Airways are the top three most popular airlines that fly to Florida Keys from Panama City, Florida according to our data. Delta is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Panama City NW Florida Beaches to Florida Keys?

Delta, American Airlines, and Southwest are the most popular carriers operating from Panama City NW Florida Beaches to Florida Keys

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Florida Keys?

Prices for flights from Panama City NW Florida Beaches Airport to Florida Keys refresh daily.

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Florida Keys?

As of May 2026, there are 2 operators available to choose from for flights from Panama City NW Florida Beaches Airport to Florida Keys.

How old do you have to be to fly from Panama City NW Florida Beaches Airport to Florida Keys?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$178 Cheap Flights from Panama City, Florida to Florida Keys in 2026

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Find the cheapest flights from Panama City, Florida to Florida Keys

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:19 am - 5:27 pm

ECP

EYW

7h 08m

1 stop

7:50 am - 12:26 pm

EYW

ECP

5h 36m

1 stop

$347Delta

Wed, Jun 10 - Wed, Jun 17

1:31 pm - 7:21 pm

ECP

MIA

4h 50m

1 stop

7:10 am - 12:26 pm

MIA

ECP

6h 16m

1 stop

$355Delta

Tue, Jun 23 - Tue, Jun 30

11:38 am - 5:23 pm

ECP

EYW

4h 45m

1 stop

7:50 am - 12:31 pm

EYW

ECP

5h 41m

1 stop

$357Delta

Fri, Jul 24 - Wed, Jul 29

7:05 am - 7:10 pm

ECP

EYW

11h 05m

2 stops

7:29 pm - 11:40 pm

EYW

ECP

5h 11m

1 stop

$362American Airlines

Wed, Jun 10 - Wed, Jun 17

6:00 am - 10:50 am

ECP

EYW

3h 50m

1 stop

7:40 am - 12:41 pm

EYW

ECP

6h 01m

1 stop

$367Delta

Fri, Aug 7 - Sat, Aug 15

11:00 am - 6:54 pm

ECP

MIA

6h 54m

1 stop

1:25 pm - 6:26 pm

MIA

ECP

6h 01m

1 stop

$374American Airlines

Mon, Jun 8 - Tue, Jun 16

6:54 pm - 12:46 am

ECP

MIA

4h 52m

1 stop

5:23 pm - 11:37 pm

MIA

ECP

7h 14m

1 stop

$375American Airlines

Fri, Jul 3 - Sat, Jul 11

6:00 am - 10:50 am

ECP

EYW

3h 50m

1 stop

7:40 am - 10:42 am

EYW

ECP

4h 02m

1 stop

$393Delta

Sat, Aug 8 - Tue, Aug 11

6:41 pm - 12:55 am

ECP

MIA

5h 14m

1 stop

12:02 pm - 4:22 pm

MIA

ECP

5h 20m

1 stop

$395Delta

Sun, Jul 12 - Thu, Jul 23

11:00 am - 6:49 pm

ECP

EYW

6h 49m

1 stop

7:29 pm - 11:40 pm

EYW

ECP

5h 11m

1 stop

$397American Airlines

Fri, May 29 - Mon, Jun 1

Southwest flights from Panama City, Florida to Florida Keys

Our best Southwest deals on Panama City, Florida to Florida Keys flight tickets

Southwest

Jun 13

ECP4:40 pmPanama City NW Florida Beaches

4h 45m

1 stop

MIA10:25 pmMiami

Jun 23

MIA3:05 pmMiami

8h 00m

1 stop

ECP10:05 pmPanama City NW Florida Beaches

$451

Southwest

Jun 23

ECP2:25 pmPanama City NW Florida Beaches

6h 25m

1 stop

MIA9:50 pmMiami

Jun 30

MIA6:00 amMiami

8h 50m

2 stops

ECP1:50 pmPanama City NW Florida Beaches

$456

Southwest

Jun 23

ECP7:00 amPanama City NW Florida Beaches

13h 20m

2 stops

MIA9:20 pmMiami

Jun 30

MIA6:35 amMiami

8h 15m

2 stops

ECP1:50 pmPanama City NW Florida Beaches

$461

Delta flights from Panama City, Florida to Florida Keys

Our best Delta deals on Panama City, Florida to Florida Keys flight tickets

Delta

Jun 10

ECP9:19 amPanama City NW Florida Beaches

7h 08m

1 stop

EYW5:27 pmKey West

Jun 17

EYW7:50 amKey West

5h 36m

1 stop

ECP12:26 pmPanama City NW Florida Beaches

$347

Delta

Jun 23

ECP5:08 pmPanama City NW Florida Beaches

4h 09m

1 stop

MIA10:17 pmMiami

Jun 30

MIA2:09 pmMiami

5h 34m

1 stop

ECP6:43 pmPanama City NW Florida Beaches

$355

Delta

Jul 24

ECP11:38 amPanama City NW Florida Beaches

4h 45m

1 stop

EYW5:23 pmKey West

Jul 29

EYW7:50 amKey West

5h 41m

1 stop

ECP12:31 pmPanama City NW Florida Beaches

$357

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Wed 6/10

9:19 am-5:27 pm

1 stop7h 08m

Key West

Wed 6/17

7:50 am-12:26 pm

1 stop5h 36m

$347

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 6/23

1:31 pm-7:21 pm

1 stop4h 50m

Miami

Tue 6/30

7:10 am-12:26 pm

1 stop6h 16m

$355

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Fri 7/24

11:38 am-5:23 pm

1 stop4h 45m

Key West

Wed 7/29

7:50 am-12:31 pm

1 stop5h 41m

$357

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Wed 6/10

7:05 am-7:10 pm

2 stops11h 05m

Key West

Wed 6/17

7:29 pm-11:40 pm

1 stop5h 11m

$362

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Fri 8/7

6:00 am-10:50 am

1 stop3h 50m

Key West

Sat 8/15

7:40 am-12:41 pm

1 stop6h 01m

$367

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Mon 6/8

11:00 am-6:54 pm

1 stop6h 54m

Miami

Tue 6/16

1:25 pm-6:26 pm

1 stop6h 01m

$374

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Fri 7/3

6:54 pm-12:46 am

1 stop4h 52m

Miami

Sat 7/11

5:23 pm-11:37 pm

1 stop7h 14m

$375

Quickest round-trip

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Sat 8/8

6:00 am-10:50 am

1 stop3h 50m

Key West

Tue 8/11

7:40 am-10:42 am

1 stop4h 02m

$393

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Sun 7/12

6:41 pm-12:55 am

1 stop5h 14m

Miami

Thu 7/23

12:02 pm-4:22 pm

1 stop5h 20m

$395

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Fri 5/29

11:00 am-6:49 pm

1 stop6h 49m

Key West

Mon 6/1

7:29 pm-11:40 pm

1 stop5h 11m

$397

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City, Florida to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Florida Keys?

The month of August is another great option to travel to Florida Keys, with average flight prices from Panama City, Florida averaging around $176.

Can stopping save me money on Panama City, Florida to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Panama City, Florida to Florida Keys.

Cheap Panama City, Florida to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Florida Keys

Fastest flight time	3h 57m
Direct flights	None

The fastest flight from Panama City, Florida to Florida Keys takes 3h 57m

There are no direct flights from Panama City, Florida to Florida Keys. There are no popular flight routes from Panama City, Florida to Florida Keys.

Search flight deals

Frequently asked questions about flying from Panama City, Florida to Florida Keys

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Florida Keys?
Prices for flights from Panama City NW Florida Beaches Airport to Florida Keys refresh daily.
How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Florida Keys?
As of May 2026, there are 2 operators available to choose from for flights from Panama City NW Florida Beaches Airport to Florida Keys.
How old do you have to be to fly from Panama City NW Florida Beaches Airport to Florida Keys?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Panama City, Florida to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Panama City, Florida to Florida Keys is Embraer 175, representing 16.16% of all bookings. The subsequent popular models are Canadair (Bombardier) Regional Jet 900 at 16.09%, Embraer 175 (Enhanced Winglets) at 15.60%, and Boeing 737 MAX 8 at 10.44%.

Best airlines flying from Panama City, Florida to Florida Keys

Compare and see reviews for airlines that fly from Panama City, Florida to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $296	Free Cancellation	Rating 7.1 11,661 reviews		Search American Airlines flights
Delta	PriceFrom $306	Free Cancellation	Rating 7.9 8,446 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Florida Keys?

It is quick and easy to find Panama City to Florida Keys flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florida Keys that suits you.

Can I find flights from Panama City to Florida Keys with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florida Keys from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Florida Keys?

Once you have performed a search for Panama City to Florida Keys flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Florida Keys right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Panama City to Florida Keys now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Florida Keys and let you know when they change.