What airlines fly to Florida Keys?

Silver Airways, American Airlines and Delta are the top three most popular airlines that fly to Florida Keys from Panama City, Florida according to our data. Silver Airways is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Panama City NW Florida Beaches to Florida Keys?

Delta, Southwest, and American Airlines are the most popular carriers operating from Panama City NW Florida Beaches to Florida Keys

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Florida Keys?

Prices for flights from Panama City NW Florida Beaches Airport to Florida Keys refresh daily.

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Florida Keys?

As of October 2025, there are 3 operators available to choose from for flights from Panama City NW Florida Beaches Airport to Florida Keys.

How old do you have to be to fly from Panama City NW Florida Beaches Airport to Florida Keys?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$159 Cheap Flights from Panama City to Florida Keys in 2025/26

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from Panama City, Florida to Florida Keys

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:32 pm - 8:06 pmECP-EYW

5h 34m1 stop

6:10 pm - 10:37 pmEYW-ECP

5h 27m1 stop

$317Delta

Find Deal

Thu, Dec 11 - Tue, Dec 16

7:05 pm - 12:57 amECP-MIA

4h 52m1 stop

8:05 am - 12:40 pmMIA-ECP

5h 35m1 stop

$317Delta

Find Deal

Tue, Mar 10 - Wed, Mar 11

2:43 pm - 9:45 pmECP-EYW

6h 02m1 stop

1:33 pm - 11:10 pmEYW-ECP

10h 37m2 stops

$322American Airlines

Find Deal

Thu, Dec 11 - Tue, Dec 16

2:43 pm - 11:07 pmECP-EYW

7h 24m2 stops

1:33 pm - 11:10 pmEYW-ECP

10h 37m2 stops

$327American Airlines

Find Deal

Thu, Dec 11 - Tue, Dec 16

6:00 am - 1:02 pmECP-MIA

6h 02m1 stop

6:00 am - 9:14 amMIA-ECP

4h 14m1 stop

$328Delta

Find Deal

Mon, Nov 24 - Tue, Dec 2

7:15 am - 1:41 pmECP-EYW

5h 26m1 stop

7:00 am - 2:13 pmEYW-ECP

8h 13m2 stops

$332American Airlines

Find Deal

Sat, Dec 6 - Thu, Dec 11

4:40 pm - 10:30 pmECP-MIA

4h 50m1 stop

7:05 am - 11:55 amMIA-ECP

5h 50m1 stop

$431Southwest

Find Deal

Sat, Feb 14 - Fri, Feb 20

10:00 am - 9:50 pmECP-MIA

10h 50m2 stops

9:30 am - 2:40 pmMIA-ECP

6h 10m1 stop

$436Southwest

Find Deal

Tue, Dec 9 - Wed, Dec 17

6:30 am - 1:46 pmECP-EYW

30h 16m3 stops

4:00 pm - 1:57 pmEYW-ECP

22h 57m2 stops

$850United Airlines

Find Deal

Sat, Nov 15 - Wed, Nov 19

6:30 am - 2:04 pmECP-EYW

30h 34m3 stops

4:00 pm - 9:19 amEYW-ECP

18h 19m2 stops

$859United Airlines

Find Deal

Tue, Nov 18 - Tue, Nov 25

Southwest flights from Panama City, Florida to Florida Keys

Our best Southwest deals on Panama City, Florida to Florida Keys flight tickets

Southwest

Feb 14

ECP4:40 pmPanama City NW Florida Beaches

4h 50m

1 stop

MIA10:30 pmMiami

Feb 20

MIA7:05 amMiami

5h 50m

1 stop

ECP11:55 amPanama City NW Florida Beaches

$431

Find similar

Southwest

Dec 9

ECP10:00 amPanama City NW Florida Beaches

10h 50m

2 stops

MIA9:50 pmMiami

Dec 17

MIA9:30 amMiami

6h 10m

1 stop

ECP2:40 pmPanama City NW Florida Beaches

$436

Find similar

Southwest

Dec 9

ECP7:15 amPanama City NW Florida Beaches

7h 55m

2 stops

MIA4:10 pmMiami

Dec 17

MIA6:55 amMiami

8h 45m

2 stops

ECP2:40 pmPanama City NW Florida Beaches

$441

Find similar

Delta flights from Panama City, Florida to Florida Keys

Our best Delta deals on Panama City, Florida to Florida Keys flight tickets

Delta

Mar 10

ECP7:05 pmPanama City NW Florida Beaches

4h 52m

1 stop

MIA12:57 amMiami

Mar 11

MIA8:05 amMiami

5h 35m

1 stop

ECP12:40 pmPanama City NW Florida Beaches

$317

Find similar

Delta

Nov 24

ECP6:00 amPanama City NW Florida Beaches

6h 02m

1 stop

MIA1:02 pmMiami

Dec 2

MIA6:00 amMiami

4h 14m

1 stop

ECP9:14 amPanama City NW Florida Beaches

$328

Find similar

Delta

Dec 3

ECP7:30 amPanama City NW Florida Beaches

6h 15m

1 stop

MIA2:45 pmMiami

Dec 8

MIA7:00 amMiami

6h 47m

1 stop

ECP12:47 pmPanama City NW Florida Beaches

$337

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 12/11

1:32 pm-8:06 pm

1 stop5h 34m

Key West

Tue 12/16

6:10 pm-10:37 pm

1 stop5h 27m

$317

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 3/10

7:05 pm-12:57 am

1 stop4h 52m

Miami

Wed 3/11

8:05 am-12:40 pm

1 stop5h 35m

$317

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 12/11

2:43 pm-9:45 pm

1 stop6h 02m

Key West

Tue 12/16

1:33 pm-11:10 pm

2 stops10h 37m

$322

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 12/11

2:43 pm-11:07 pm

2 stops7h 24m

Key West

Tue 12/16

1:33 pm-11:10 pm

2 stops10h 37m

$327

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Mon 11/24

6:00 am-1:02 pm

1 stop6h 02m

Miami

Tue 12/2

6:00 am-9:14 am

1 stop4h 14m

$328

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Sat 12/6

7:15 am-1:41 pm

1 stop5h 26m

Key West

Thu 12/11

7:00 am-2:13 pm

2 stops8h 13m

$332

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Sat 2/14

4:40 pm-10:30 pm

1 stop4h 50m

Miami

Fri 2/20

7:05 am-11:55 am

1 stop5h 50m

$431

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 12/9

10:00 am-9:50 pm

2 stops10h 50m

Miami

Wed 12/17

9:30 am-2:40 pm

1 stop6h 10m

$436

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Sat 11/15

6:30 am-1:46 pm

3 stops30h 16m

Key West

Wed 11/19

4:00 pm-1:57 pm

2 stops22h 57m

$850

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 11/18

6:30 am-2:04 pm

3 stops30h 34m

Key West

Tue 11/25

4:00 pm-9:19 am

2 stops18h 19m

$859

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City, Florida to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from Panama City, Florida averaging around $306.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Panama City, Florida to Florida Keys is on a Tuesday when prices can be found for as low as $352. The most expensive day to fly to Florida Keys is Sunday, with ticket prices averaging around $597.

How far in advance should I book a flight to Florida Keys?

You are more likely to see cheaper flights to Florida Keys from Panama City, Florida when booking weeks ahead of your departure date. In general, you can expect to find flights to Florida Keys for around $424 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Florida Keys from Panama City, Florida for as low as $244 on momondo.

Can stopping save me money on Panama City, Florida to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Panama City, Florida to Florida Keys.

Cheap Panama City, Florida to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Florida Keys

Direct flights	None

There are no direct flights from Panama City, Florida to Florida Keys. There are no popular flight routes from Panama City, Florida to Florida Keys.

Search flight deals

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Florida Keys?
Prices for flights from Panama City NW Florida Beaches Airport to Florida Keys refresh daily.
How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Florida Keys?
As of October 2025, there are 3 operators available to choose from for flights from Panama City NW Florida Beaches Airport to Florida Keys.
How old do you have to be to fly from Panama City NW Florida Beaches Airport to Florida Keys?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Panama City, Florida to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Panama City, Florida to Florida Keys is Canadair (Bombardier) Regional Jet 900, representing 18.35% of all bookings. The subsequent popular models are Embraer 175 (Enhanced Winglets) at 17.00%, Embraer 175 at 12.88%, and Boeing 737-700 Passenger/BBJ1 (winglets) at 12.13%.

Best airlines flying from Panama City, Florida to Florida Keys

Compare and see reviews for airlines that fly from Panama City, Florida to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $296	Free Cancellation	Rating 7.2 11,035 reviews		Search American Airlines flights
Delta	PriceFrom $306	Free Cancellation	Rating 7.9 7,998 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Florida Keys?

It is quick and easy to find Panama City to Florida Keys flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florida Keys that suits you.

Can I find flights from Panama City to Florida Keys with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florida Keys from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Florida Keys?

Once you have performed a search for Panama City to Florida Keys flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Florida Keys right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Panama City to Florida Keys now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Florida Keys and let you know when they change.

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Sat 11/29

Sat 12/6

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Flights to New Yorkfrom $49

Flights to Los Angelesfrom $47

Flights to Miamifrom $47

Flights to Chicagofrom $49

Flights to Orlandofrom $47

Flights to Las Vegasfrom $39

Flights to San Franciscofrom $39

Flights to Washington, D.C.from $40

Flights to Bostonfrom $60

Flights to Atlantafrom $47

Flights to Dallasfrom $49

Flights to Seattlefrom $53

Panama City, Florida flight routes

Flights from Panama City NW Florida Beaches to Austin Bergstrom

Flights from Panama City NW Florida Beaches to Atlanta Hartsfield-Jackson

Flights from Panama City NW Florida Beaches to Chicago O'Hare Intl

Flights from Panama City NW Florida Beaches to Nashville Intl

Flights from Panama City NW Florida Beaches to Houston George Bush Intcntl

Flights from Panama City NW Florida Beaches to Dallas/Fort Worth

Cheap flights from Panama City, Florida to Florida Keys from $159

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Panama City, Florida to Florida Keys

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Southwest flights from Panama City, Florida to Florida Keys

Our best Southwest deals on Panama City, Florida to Florida Keys flight tickets

Delta flights from Panama City, Florida to Florida Keys

Our best Delta deals on Panama City, Florida to Florida Keys flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to Florida Keys that are best for you.

See travel insights to Florida Keys from

How to get the cheapest flight ticket from Panama City, Florida to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from Panama City, Florida averaging around $306.

What is the cheapest day to depart on your flight to Florida Keys?

The cheapest day to depart from Panama City, Florida to Florida Keys is on a Tuesday when prices can be found for as low as $352. The most expensive day to fly to Florida Keys is Sunday, with ticket prices averaging around $597.

How far in advance should I book a flight to Florida Keys?

Can stopping save me money on Panama City, Florida to Florida Keys flights?

No. A direct flight is the cheapest option for a flight between Panama City, Florida to Florida Keys.

What is the cheapest airline that flies from Panama City NW Florida Beaches to Florida Keys?

Delta, Southwest, and American Airlines are the most popular carriers operating from Panama City NW Florida Beaches to Florida Keys

What airlines fly to Florida Keys?

Cheap Panama City, Florida to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Florida Keys

Direct flights

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Florida Keys?

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Florida Keys?

How old do you have to be to fly from Panama City NW Florida Beaches Airport to Florida Keys?

What documentation or ID do you need to fly to Florida Keys?

What is the most popular plane model from Panama City, Florida to Florida Keys?

Best airlines flying from Panama City, Florida to Florida Keys

Compare and see reviews for airlines that fly from Panama City, Florida to Florida Keys with momondo

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Florida Keys?

Can I find flights from Panama City to Florida Keys with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to Florida Keys?

I’m not ready to book a flight from Panama City to Florida Keys right now. Can momondo alert me if prices change?

An easier way to manage your Florida Keys trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Florida Keys

Popular cities in Florida Keys

Popular flights according to clicks in the last 7 days on momondo