What airlines fly to Florida Keys?

Delta, American Airlines and Silver Airways are the top three most popular airlines that fly to Florida Keys from Panama City, Florida according to our data. Delta is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Florida Keys. Keep in mind that there are 3 different airlines that fly to Florida Keys on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Panama City NW Florida Beaches to Florida Keys?

Delta, Southwest, and American Airlines are the most popular carriers operating from Panama City NW Florida Beaches to Florida Keys

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Florida Keys?

Prices for flights from Panama City NW Florida Beaches Airport to Florida Keys refresh daily.

How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Florida Keys?

As of March 2026, there are 3 operators available to choose from for flights from Panama City NW Florida Beaches Airport to Florida Keys.

How old do you have to be to fly from Panama City NW Florida Beaches Airport to Florida Keys?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Florida Keys.

What documentation or ID do you need to fly to Florida Keys?

The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$178 Cheap Flights from Panama City to Florida Keys in 2026

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Find the cheapest flights from Panama City, Florida to Florida Keys

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:05 am - 1:07 pm

ECP

MIA

5h 02m

1 stop

5:18 pm - 11:40 pm

MIA

ECP

7h 22m

1 stop

$355American Airlines

Wed, Jun 17 - Wed, Jun 17

7:10 am - 3:20 pm

ECP

MIA

7h 10m

1 stop

12:10 pm - 6:55 pm

MIA

ECP

7h 45m

1 stop

$371Southwest

Thu, Apr 30 - Wed, May 6

10:48 am - 4:55 pm

ECP

MIA

5h 07m

1 stop

7:45 am - 11:48 am

MIA

ECP

5h 03m

1 stop

$375American Airlines

Wed, Apr 29 - Mon, May 4

6:40 am - 6:25 pm

ECP

MIA

10h 45m

2 stops

12:10 pm - 6:55 pm

MIA

ECP

7h 45m

1 stop

$376Southwest

Thu, Apr 30 - Wed, May 6

2:50 pm - 7:49 pm

ECP

EYW

3h 59m

1 stop

7:45 am - 12:26 pm

EYW

ECP

5h 41m

1 stop

$383Delta

Tue, Jun 2 - Tue, Jun 9

4:40 pm - 10:36 pm

ECP

EYW

4h 56m

1 stop

5:25 pm - 10:52 pm

EYW

ECP

6h 27m

1 stop

$387American Airlines

Fri, Apr 17 - Tue, Apr 21

12:18 pm - 10:58 pm

ECP

EYW

9h 40m

2 stops

5:25 pm - 10:52 pm

EYW

ECP

6h 27m

1 stop

$392American Airlines

Fri, Apr 17 - Tue, Apr 21

5:49 am - 10:46 am

ECP

EYW

3h 57m

1 stop

7:33 am - 12:41 pm

EYW

ECP

6h 08m

1 stop

$403Delta

Mon, Apr 20 - Mon, Apr 27

7:05 pm - 12:56 am

ECP

MIA

4h 51m

1 stop

7:00 am - 10:14 am

MIA

ECP

4h 14m

1 stop

$407Delta

Thu, Jul 9 - Tue, Jul 14

1:33 pm - 7:40 pm

ECP

EYW

5h 07m

1 stop

6:18 pm - 11:12 pm

EYW

ECP

5h 54m

1 stop

$438Delta

Thu, Apr 23 - Sat, Apr 25

Delta flights from Panama City, Florida to Florida Keys

Our best Delta deals on Panama City, Florida to Florida Keys flight tickets

Delta

Jun 2

ECP2:50 pmPanama City NW Florida Beaches

3h 59m

1 stop

EYW7:49 pmKey West

Jun 9

EYW7:45 amKey West

5h 41m

1 stop

ECP12:26 pmPanama City NW Florida Beaches

$383

Delta

Apr 24

ECP5:49 amPanama City NW Florida Beaches

3h 57m

1 stop

EYW10:46 amKey West

Apr 28

EYW6:23 pmKey West

5h 49m

1 stop

ECP11:12 pmPanama City NW Florida Beaches

$393

Delta

Apr 20

ECP5:49 amPanama City NW Florida Beaches

3h 57m

1 stop

EYW10:46 amKey West

Apr 27

EYW7:33 amKey West

6h 08m

1 stop

ECP12:41 pmPanama City NW Florida Beaches

$403

American Airlines flights from Panama City, Florida to Florida Keys

Our best American Airlines deals on Panama City, Florida to Florida Keys flight tickets

American Airlines

Jun 17

ECP7:05 amPanama City NW Florida Beaches

5h 02m

1 stop

MIA1:07 pmMiami

Jun 17

MIA5:18 pmMiami

7h 22m

1 stop

ECP11:40 pmPanama City NW Florida Beaches

$355

American Airlines

Apr 29

ECP10:48 amPanama City NW Florida Beaches

5h 07m

1 stop

MIA4:55 pmMiami

May 4

MIA7:45 amMiami

5h 03m

1 stop

ECP11:48 amPanama City NW Florida Beaches

$375

American Airlines

Apr 17

ECP4:40 pmPanama City NW Florida Beaches

4h 56m

1 stop

EYW10:36 pmKey West

Apr 21

EYW5:25 pmKey West

6h 27m

1 stop

ECP10:52 pmPanama City NW Florida Beaches

$387

momondo Fare Finder

Use the filters below to find and compare flights from Panama City, Florida to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Wed 6/17

7:05 am-1:07 pm

1 stop5h 02m

Miami

Wed 6/17

5:18 pm-11:40 pm

1 stop7h 22m

$355

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Thu 4/30

7:10 am-3:20 pm

1 stop7h 10m

Miami

Wed 5/6

12:10 pm-6:55 pm

1 stop7h 45m

$371

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Wed 4/29

10:48 am-4:55 pm

1 stop5h 07m

Miami

Mon 5/4

7:45 am-11:48 am

1 stop5h 03m

$375

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Thu 4/30

6:40 am-6:25 pm

2 stops10h 45m

Miami

Wed 5/6

12:10 pm-6:55 pm

1 stop7h 45m

$376

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Tue 6/2

2:50 pm-7:49 pm

1 stop3h 59m

Key West

Tue 6/9

7:45 am-12:26 pm

1 stop5h 41m

$383

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Fri 4/17

4:40 pm-10:36 pm

1 stop4h 56m

Key West

Tue 4/21

5:25 pm-10:52 pm

1 stop6h 27m

$387

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Fri 4/17

12:18 pm-10:58 pm

2 stops9h 40m

Key West

Tue 4/21

5:25 pm-10:52 pm

1 stop6h 27m

$392

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Mon 4/20

5:49 am-10:46 am

1 stop3h 57m

Key West

Mon 4/27

7:33 am-12:41 pm

1 stop6h 08m

$403

Quickest round-trip

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Thu 7/9

7:05 pm-12:56 am

1 stop4h 51m

Miami

Tue 7/14

7:00 am-10:14 am

1 stop4h 14m

$407

Panama CityKey West

ECP - EYW

ECPEYW

Panama City NW Florida Beaches

Thu 4/23

1:33 pm-7:40 pm

1 stop5h 07m

Key West

Sat 4/25

6:18 pm-11:12 pm

1 stop5h 54m

$438

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City, Florida to Florida Keys

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Florida Keys?

The month of September is another great option to travel to Florida Keys, with average flight prices from Panama City, Florida averaging around $306.

Can stopping save me money on Panama City, Florida to Florida Keys flights?

You could potentially save up to 17% on your flight if you consider stops on a Panama City, Florida to Florida Keys flight.

Cheap Panama City, Florida to Florida Keys flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Florida Keys

Fastest flight time	3h 57m
Direct flights	None

The fastest flight from Panama City, Florida to Florida Keys takes 3h 57m

There are no direct flights from Panama City, Florida to Florida Keys. There are no popular flight routes from Panama City, Florida to Florida Keys.

Search flight deals

When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Florida Keys?
Prices for flights from Panama City NW Florida Beaches Airport to Florida Keys refresh daily.
How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Florida Keys?
As of March 2026, there are 3 operators available to choose from for flights from Panama City NW Florida Beaches Airport to Florida Keys.
How old do you have to be to fly from Panama City NW Florida Beaches Airport to Florida Keys?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Florida Keys.
What documentation or ID do you need to fly to Florida Keys?
The required travel and health documents for your Florida Keys trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Florida Keys. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Panama City, Florida to Florida Keys?
momondo data reveals that the most frequently booked plane model on the route from Panama City, Florida to Florida Keys is Canadair (Bombardier) Regional Jet 900, representing 21.36% of all bookings. The subsequent popular models are Embraer 175 at 13.34%, Embraer 175 (Enhanced Winglets) at 13.18%, and Boeing 737 MAX 8 at 9.87%.

Best airlines flying from Panama City, Florida to Florida Keys

Compare and see reviews for airlines that fly from Panama City, Florida to Florida Keys with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $296	Free Cancellation	Rating 7.1 11,489 reviews		Search American Airlines flights
Delta	PriceFrom $306	Free Cancellation	Rating 7.9 8,319 reviews		Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Florida Keys?

It is quick and easy to find Panama City to Florida Keys flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Florida Keys that suits you.

Can I find flights from Panama City to Florida Keys with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florida Keys from Panama City which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama City to Florida Keys?

Once you have performed a search for Panama City to Florida Keys flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Florida Keys right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Panama City to Florida Keys now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Florida Keys and let you know when they change.