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Cheap flights from Panama City, Florida to Charleston from $183

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Charleston departing on 4/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to Charleston

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
10:48 am - 4:06 pm
ECP
-
CHS
4h 18m
1 stop
American Airlines Logo
8:21 pm - 11:46 pm
CHS
-
ECP
4h 25m
1 stop
$365American Airlines
Mon, May 4 - Thu, May 7
Southwest Logo
12:05 pm - 8:00 pm
ECP
-
CHS
6h 55m
1 stop
Southwest Logo
2:15 pm - 6:20 pm
CHS
-
ECP
5h 05m
1 stop
$366Southwest
Wed, May 13 - Fri, May 15
Southwest Logo
7:55 am - 8:00 pm
ECP
-
CHS
11h 05m
2 stops
Southwest Logo
2:15 pm - 6:20 pm
CHS
-
ECP
5h 05m
1 stop
$371Southwest
Wed, May 13 - Fri, May 15
American Airlines Logo
4:16 pm - 11:59 pm
ECP
-
CHS
6h 43m
1 stop
American Airlines Logo
5:00 am - 10:28 am
CHS
-
ECP
6h 28m
1 stop
$395American Airlines
Fri, May 22 - Mon, May 25
Southwest Logo
6:55 am - 4:05 pm
ECP
-
CHS
8h 10m
2 stops
Southwest Logo
6:25 am - 9:35 am
CHS
-
ECP
4h 10m
1 stop
$400Southwest
Fri, Jul 10 - Mon, Jul 13
Southwest Logo
6:55 am - 4:05 pm
ECP
-
CHS
8h 10m
2 stops
Southwest Logo
6:25 am - 12:45 pm
CHS
-
ECP
7h 20m
2 stops
$405Southwest
Fri, Jul 10 - Mon, Jul 13
Delta Logo
7:05 am - 1:35 pm
ECP
-
CHS
5h 30m
1 stop
Delta Logo
7:44 pm - 11:12 pm
CHS
-
ECP
4h 28m
1 stop
$417Delta
Wed, Apr 15 - Thu, Apr 16
Southwest Logo
7:10 am - 6:20 pm
ECP
-
CHS
10h 10m
1 stop
Southwest Logo
1:15 pm - 9:40 pm
CHS
-
ECP
9h 25m
2 stops
$429Southwest
Mon, May 4 - Thu, May 7
Southwest Logo
6:40 am - 4:10 pm
ECP
-
CHS
8h 30m
2 stops
Southwest Logo
1:15 pm - 9:40 pm
CHS
-
ECP
9h 25m
2 stops
$439Southwest
Mon, May 4 - Thu, May 7
Southwest Logo
12:05 pm - 8:00 pm
ECP
-
CHS
6h 55m
1 stop
Southwest Logo
8:05 am - 7:50 pm
CHS
-
ECP
12h 45m
2 stops
$444Southwest
Wed, Apr 15 - Thu, Apr 16

American Airlines flights from Panama City, Florida to Charleston

Our best American Airlines deals on Panama City, Florida to Charleston flight tickets
American Airlines
May 4
ECP10:48 amPanama City NW Florida Beaches
4h 18m
1 stop
CHS4:06 pmCharleston
May 7
CHS8:21 pmCharleston
4h 25m
1 stop
ECP11:46 pmPanama City NW Florida Beaches
$365
American Airlines
May 22
ECP4:16 pmPanama City NW Florida Beaches
6h 43m
1 stop
CHS11:59 pmCharleston
May 25
CHS5:00 amCharleston
6h 28m
1 stop
ECP10:28 amPanama City NW Florida Beaches
$395
American Airlines
Apr 18
ECP7:21 amPanama City NW Florida Beaches
5h 48m
1 stop
CHS2:09 pmCharleston
Apr 19
CHS6:35 amCharleston
4h 28m
1 stop
ECP10:03 amPanama City NW Florida Beaches
$471

Southwest flights from Panama City, Florida to Charleston

Our best Southwest deals on Panama City, Florida to Charleston flight tickets
Southwest
May 13
ECP12:05 pmPanama City NW Florida Beaches
6h 55m
1 stop
CHS8:00 pmCharleston
May 15
CHS2:15 pmCharleston
5h 05m
1 stop
ECP6:20 pmPanama City NW Florida Beaches
$366
Southwest
May 13
ECP7:55 amPanama City NW Florida Beaches
11h 05m
2 stops
CHS8:00 pmCharleston
May 15
CHS2:15 pmCharleston
5h 05m
1 stop
ECP6:20 pmPanama City NW Florida Beaches
$371
Southwest
Jul 10
ECP6:55 amPanama City NW Florida Beaches
8h 10m
2 stops
CHS4:05 pmCharleston
Jul 13
CHS6:25 amCharleston
4h 10m
1 stop
ECP9:35 amPanama City NW Florida Beaches
$400

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Mon 5/4

10:48 am-4:06 pm

1 stop4h 18m

Charleston

Thu 5/7

8:21 pm-11:46 pm

1 stop4h 25m

$365

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 5/13

12:05 pm-8:00 pm

1 stop6h 55m

Charleston

Fri 5/15

2:15 pm-6:20 pm

1 stop5h 05m

$366

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 5/13

7:55 am-8:00 pm

2 stops11h 05m

Charleston

Fri 5/15

2:15 pm-6:20 pm

1 stop5h 05m

$371

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 5/22

4:16 pm-11:59 pm

1 stop6h 43m

Charleston

Mon 5/25

5:00 am-10:28 am

1 stop6h 28m

$395

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 7/10

6:55 am-4:05 pm

2 stops8h 10m

Charleston

Mon 7/13

6:25 am-9:35 am

1 stop4h 10m

$400

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 7/10

6:55 am-4:05 pm

2 stops8h 10m

Charleston

Mon 7/13

6:25 am-12:45 pm

2 stops7h 20m

$405

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 4/15

7:05 am-1:35 pm

1 stop5h 30m

Charleston

Thu 4/16

7:44 pm-11:12 pm

1 stop4h 28m

$417

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Mon 5/4

7:10 am-6:20 pm

1 stop10h 10m

Charleston

Thu 5/7

1:15 pm-9:40 pm

2 stops9h 25m

$429

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Mon 5/4

6:40 am-4:10 pm

2 stops8h 30m

Charleston

Thu 5/7

1:15 pm-9:40 pm

2 stops9h 25m

$439

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 4/15

12:05 pm-8:00 pm

1 stop6h 55m

Charleston

Thu 4/16

8:05 am-7:50 pm

2 stops12h 45m

$444

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Charleston from

How to get the cheapest flight ticket from Panama City, Florida to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Panama City NW Florida Beaches to Charleston?

American Airlines and Southwest are the most popular carriers operating from Panama City NW Florida Beaches to Charleston

What airlines fly to Charleston?

Delta, American Airlines and Spirit Airlines are the top three most popular airlines that fly to Charleston from Panama City, Florida according to our data. Delta is the first choice among our users, with 71% of people opting to fly with this airline when traveling to Charleston. Keep in mind that there are 3 different airlines that fly to Charleston on a routine basis, so you have a few additional options to choose from.

When to book flights from Panama City, Florida to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Charleston (ECP to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Charleston

Fastest flight time

4h 50m

Direct flights

None
The fastest flight from Panama City, Florida to Charleston takes 4h 50m
There are no direct flights from Panama City, Florida to Charleston. There are no popular flight routes from Panama City, Florida to Charleston.
Search flight deals

  • How far is Panama City NW Florida Beaches to Charleston by plane?

    There are 382.6 mi between Panama City NW Florida Beaches and Charleston. 4h 50m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Charleston Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Charleston Airport were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Charleston Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Charleston Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The travel and health documents required for your trip to Charleston Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charleston Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Panama City, Florida to Charleston?

Best airlines flying from Panama City, Florida to Charleston

Compare and see reviews for airlines that fly from Panama City, Florida to Charleston with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $196Free CancellationRating
7.9
8,288 reviews
Search Delta flights
American AirlinesPriceFrom $276Free CancellationRating
7.1
11,468 reviews
Search American Airlines flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Summerville
Kiawah Island
Mount Pleasant
Edisto Island
Santee
Walterboro
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Charleston?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Charleston. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Charleston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Charleston flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Charleston?

momondo provides multiple filters to help you find the best flight to Charleston from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Charleston right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Charleston flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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