Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Panama City, Florida to Charleston from $164

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Charleston departing on 11/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Panama City, Florida to Charleston

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
1:30 pm - 6:55 pmECP-CHS
4h 25m1 stop
Delta Logo
4:30 pm - 7:36 pmCHS-ECP
4h 06m1 stop
$317Delta
Find Deal
Tue, Apr 14 - Wed, Apr 15
Delta Logo
1:32 pm - 7:08 pmECP-CHS
4h 36m1 stop
Delta Logo
4:00 pm - 8:31 pmCHS-ECP
5h 31m1 stop
$327Delta
Find Deal
Fri, Dec 12 - Mon, Dec 15
Southwest Logo
5:35 pm - 10:55 pmECP-CHS
4h 20m1 stop
Southwest Logo
6:00 am - 2:40 pmCHS-ECP
9h 40m2 stops
$332Southwest
Find Deal
Fri, Dec 12 - Mon, Dec 15
Southwest Logo
1:30 pm - 11:30 pmECP-CHS
9h 00m2 stops
Southwest Logo
6:00 am - 3:50 pmCHS-ECP
10h 50m2 stops
$337Southwest
Find Deal
Fri, Dec 12 - Mon, Dec 15
Southwest Logo
6:35 pm - 11:10 pmECP-CHS
3h 35m1 stop
Southwest Logo
6:00 am - 3:50 pmCHS-ECP
10h 50m2 stops
$338Southwest
Find Deal
Mon, Dec 29 - Thu, Jan 1
Delta Logo
6:00 am - 10:20 amECP-CHS
3h 20m1 stop
Delta Logo
8:10 am - 12:40 pmCHS-ECP
5h 30m1 stop
$345Delta
Find Deal
Fri, Oct 31 - Tue, Nov 4
Delta Logo
6:00 am - 1:25 pmECP-CHS
6h 25m1 stop
Delta Logo
8:20 pm - 11:07 pmCHS-ECP
3h 47m1 stop
$348Delta
Find Deal
Mon, Nov 24 - Sun, Nov 30
American Airlines Logo
3:41 pm - 8:43 pmECP-CHS
4h 02m1 stop
American Airlines Logo
6:00 am - 4:44 pmCHS-ECP
11h 44m2 stops
$350American Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 4
American Airlines Logo
11:58 am - 11:59 pmECP-CHS
11h 01m2 stops
American Airlines Logo
7:53 pm - 11:49 pmCHS-ECP
4h 56m1 stop
$416American Airlines
Find Deal
Wed, Oct 29 - Sun, Nov 2
American Airlines Logo
5:00 pm - 9:14 pmECP-CHS
3h 14m1 stop
American Airlines Logo
7:40 am - 3:17 pmCHS-ECP
8h 37m2 stops
$420American Airlines
Find Deal
Tue, Apr 14 - Wed, Apr 15

Delta flights from Panama City, Florida to Charleston

Our best Delta deals on Panama City, Florida to Charleston flight tickets
Delta
Apr 14
ECP1:30 pmPanama City NW Florida Beaches
4h 25m
1 stop
CHS6:55 pmCharleston
Apr 15
CHS4:30 pmCharleston
4h 06m
1 stop
ECP7:36 pmPanama City NW Florida Beaches
$317
Find similar
Delta
Dec 12
ECP1:32 pmPanama City NW Florida Beaches
4h 36m
1 stop
CHS7:08 pmCharleston
Dec 15
CHS4:00 pmCharleston
5h 31m
1 stop
ECP8:31 pmPanama City NW Florida Beaches
$327
Find similar
Delta
Oct 31
ECP6:00 amPanama City NW Florida Beaches
3h 20m
1 stop
CHS10:20 amCharleston
Nov 4
CHS8:10 amCharleston
5h 30m
1 stop
ECP12:40 pmPanama City NW Florida Beaches
$345
Find similar

Southwest flights from Panama City, Florida to Charleston

Our best Southwest deals on Panama City, Florida to Charleston flight tickets
Southwest
Dec 12
ECP5:35 pmPanama City NW Florida Beaches
4h 20m
1 stop
CHS10:55 pmCharleston
Dec 15
CHS6:00 amCharleston
9h 40m
2 stops
ECP2:40 pmPanama City NW Florida Beaches
$332
Find similar
Southwest
Dec 12
ECP1:30 pmPanama City NW Florida Beaches
9h 00m
2 stops
CHS11:30 pmCharleston
Dec 15
CHS6:00 amCharleston
10h 50m
2 stops
ECP3:50 pmPanama City NW Florida Beaches
$337
Find similar
Southwest
Dec 29
ECP6:35 pmPanama City NW Florida Beaches
3h 35m
1 stop
CHS11:10 pmCharleston
Jan 1
CHS6:00 amCharleston
10h 50m
2 stops
ECP3:50 pmPanama City NW Florida Beaches
$338
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Tue 4/14

1:30 pm-6:55 pm

1 stop4h 25m

Charleston

Wed 4/15

4:30 pm-7:36 pm

1 stop4h 06m

$317

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 12/12

1:32 pm-7:08 pm

1 stop4h 36m

Charleston

Mon 12/15

4:00 pm-8:31 pm

1 stop5h 31m

$327

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 12/12

5:35 pm-10:55 pm

1 stop4h 20m

Charleston

Mon 12/15

6:00 am-2:40 pm

2 stops9h 40m

$332

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 12/12

1:30 pm-11:30 pm

2 stops9h 00m

Charleston

Mon 12/15

6:00 am-3:50 pm

2 stops10h 50m

$337

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Mon 12/29

6:35 pm-11:10 pm

1 stop3h 35m

Charleston

Thu 1/1

6:00 am-3:50 pm

2 stops10h 50m

$338

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 10/31

6:00 am-10:20 am

1 stop3h 20m

Charleston

Tue 11/4

8:10 am-12:40 pm

1 stop5h 30m

$345

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Mon 11/24

6:00 am-1:25 pm

1 stop6h 25m

Charleston

Sun 11/30

8:20 pm-11:07 pm

1 stop3h 47m

$348

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Fri 10/31

3:41 pm-8:43 pm

1 stop4h 02m

Charleston

Tue 11/4

6:00 am-4:44 pm

2 stops11h 44m

$350

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 10/29

11:58 am-11:59 pm

2 stops11h 01m

Charleston

Sun 11/2

7:53 pm-11:49 pm

1 stop4h 56m

$416

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Tue 4/14

5:00 pm-9:14 pm

1 stop3h 14m

Charleston

Wed 4/15

7:40 am-3:17 pm

2 stops8h 37m

$420

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

See travel insights to Charleston from

How to get the cheapest flight ticket from Panama City, Florida to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Panama City, Florida is in August. Flight prices, which tend to average around $266, are often lower during this time because this is during the off-season. The month of October is another great option to travel to Charleston, with average flight prices from Panama City, Florida averaging around $316.

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Panama City, Florida to Charleston is on a Wednesday. Travelers who choose to depart for Charleston on a Wednesday will often find tickets for as low as $286. The most expensive day to fly to Charleston is Sunday, with ticket prices averaging around $523.

When to book flights from Panama City, Florida to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Charleston according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Charleston (ECP to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Charleston

Direct flights

None
There are no direct flights from Panama City, Florida to Charleston. There are no popular flight routes from Panama City, Florida to Charleston.
Search flight deals

  • How far is Panama City NW Florida Beaches to Charleston by plane?

    There are 382.6 mi between Panama City NW Florida Beaches and Charleston. 3h 10m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Charleston Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Charleston Airport were last updated today.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Charleston Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Charleston Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Panama City NW Florida Beaches Airport to Charleston Airport.

  • What documentation or ID do you need to fly to Charleston Airport?

    The travel and health documents required for your trip to Charleston Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Charleston Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Panama City, Florida to Charleston?

Best airlines flying from Panama City, Florida to Charleston

Compare and see reviews for airlines that fly from Panama City, Florida to Charleston with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $221Free CancellationRating
7.9
7,984 reviews
Search Delta flights

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Folly Beach
Isle of Palms
North Charleston
Kiawah Island
Summerville
Mount Pleasant
Edisto Island
Santee
Walterboro
Goose Creek
Edisto Beach
Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Charleston?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama City to Charleston. momondo saves you time and could save you money on your trip.

Can I find flights from Panama City to Charleston with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Panama City to Charleston flights to just show those with flexible booking policies.

How can momondo help me find flights from Panama City to Charleston?

momondo provides multiple filters to help you find the best flight to Charleston from Panama City. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama City to Charleston right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Charleston flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Charleston trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 11/15
Sat 11/22
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States