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Cheap flights from Orlando to Des Moines from $79

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando to Des Moines departing on 5/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Orlando to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
12:07 pm - 10:57 pm
MCO
-
DSM
11h 50m
1 stop
Multiple Airlines Logo
7:00 am - 1:40 pm
DSM
-
MCO
29h 40m
1 stop
$194Multiple Airlines
Fri, May 8 - Sun, May 10
Multiple Airlines Logo
3:10 pm - 9:09 pm
MCO
-
DSM
6h 59m
1 stop
Multiple Airlines Logo
9:59 pm - 1:52 pm
DSM
-
MCO
14h 53m
1 stop
$226Multiple Airlines
Fri, May 22 - Mon, May 25
Frontier Logo
8:33 pm - 1:31 pm
MCO
-
DSM
17h 58m
1 stop
Frontier Logo
2:16 pm - 11:43 am
DSM
-
MCO
20h 27m
1 stop
$232Frontier
Thu, May 28 - Mon, Jun 1
Multiple Airlines Logo
12:07 pm - 10:57 pm
MCO
-
DSM
11h 50m
1 stop
Multiple Airlines Logo
7:45 am - 6:40 am
DSM
-
MCO
21h 55m
2 stops
$233Multiple Airlines
Fri, May 8 - Sun, May 10
Multiple Airlines Logo
10:50 am - 10:57 pm
MCO
-
DSM
13h 07m
1 stop
Multiple Airlines Logo
7:45 am - 10:25 pm
DSM
-
MCO
13h 40m
1 stop
$234Multiple Airlines
Fri, May 15 - Sun, May 17
Multiple Airlines Logo
6:00 am - 1:46 pm
MCO
-
DSM
8h 46m
1 stop
Multiple Airlines Logo
6:48 pm - 1:52 pm
DSM
-
MCO
18h 04m
1 stop
$237Multiple Airlines
Thu, May 14 - Mon, May 18
Multiple Airlines Logo
10:50 am - 10:57 pm
MCO
-
DSM
13h 07m
1 stop
Multiple Airlines Logo
6:48 pm - 1:52 pm
DSM
-
MCO
18h 04m
1 stop
$238Multiple Airlines
Fri, May 15 - Mon, May 18
Multiple Airlines Logo
12:07 pm - 10:57 pm
MCO
-
DSM
11h 50m
1 stop
Multiple Airlines Logo
6:48 pm - 4:57 pm
DSM
-
MCO
21h 09m
1 stop
$241Multiple Airlines
Fri, May 15 - Mon, May 18
Multiple Airlines Logo
6:41 pm - 3:15 pm
MCO
-
DSM
21h 34m
1 stop
Multiple Airlines Logo
7:00 am - 1:40 pm
DSM
-
MCO
29h 40m
1 stop
$243Multiple Airlines
Wed, May 6 - Sun, May 10
Multiple Airlines Logo
9:51 am - 10:58 pm
MCO
-
DSM
14h 07m
2 stops
Multiple Airlines Logo
5:02 pm - 12:54 pm
DSM
-
MCO
18h 52m
1 stop
$244Multiple Airlines
Thu, Jun 25 - Sun, Jun 28

Frontier flights from Orlando to Des Moines

Our best Frontier deals on Orlando to Des Moines flight tickets
Frontier
May 28
MCO8:33 pmOrlando
17h 58m
1 stop
DSM1:31 pmDes Moines
Jun 1
DSM2:16 pmDes Moines
20h 27m
1 stop
MCO11:43 amOrlando
$232
Frontier
Jun 26
MCO6:00 amOrlando
8h 31m
1 stop
DSM1:31 pmDes Moines
Jun 29
DSM2:16 pmDes Moines
20h 31m
1 stop
MCO11:47 amOrlando
$261
Frontier
May 15
MCO6:00 amOrlando
8h 31m
1 stop
DSM1:31 pmDes Moines
May 18
DSM2:16 pmDes Moines
14h 17m
1 stop
MCO5:33 amOrlando
$277

American Airlines flights from Orlando to Des Moines

Our best American Airlines deals on Orlando to Des Moines flight tickets
American Airlines
May 12
MCO7:00 amOrlando
6h 55m
1 stop
DSM12:55 pmDes Moines
May 13
DSM7:05 amDes Moines
6h 08m
1 stop
MCO2:13 pmOrlando
$287
American Airlines
May 23
MCO5:39 pmOrlando
7h 38m
1 stop
DSM12:17 amDes Moines
May 26
DSM6:02 amDes Moines
7h 55m
1 stop
MCO2:57 pmOrlando
$304
American Airlines
May 12
MCO6:09 amOrlando
8h 39m
1 stop
DSM1:48 pmDes Moines
May 20
DSM7:11 amDes Moines
9h 44m
1 stop
MCO5:55 pmOrlando
$307

momondo Fare Finder

 
Customize your flight search to find flights from Orlando to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from Orlando to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 5/8

12:07 pm-10:57 pm

1 stop11h 50m

Des Moines

Sun 5/10

7:00 am-1:40 pm

1 stop29h 40m

$194
Quickest round-trip

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 5/22

3:10 pm-9:09 pm

1 stop6h 59m

Des Moines

Mon 5/25

9:59 pm-1:52 pm

1 stop14h 53m

$226

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 5/28

8:33 pm-1:31 pm

1 stop17h 58m

Des Moines

Mon 6/1

2:16 pm-11:43 am

1 stop20h 27m

$232

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 5/8

12:07 pm-10:57 pm

1 stop11h 50m

Des Moines

Sun 5/10

7:45 am-6:40 am

2 stops21h 55m

$233

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 5/15

10:50 am-10:57 pm

1 stop13h 07m

Des Moines

Sun 5/17

7:45 am-10:25 pm

1 stop13h 40m

$234

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 5/14

6:00 am-1:46 pm

1 stop8h 46m

Des Moines

Mon 5/18

6:48 pm-1:52 pm

1 stop18h 04m

$237

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 5/15

10:50 am-10:57 pm

1 stop13h 07m

Des Moines

Mon 5/18

6:48 pm-1:52 pm

1 stop18h 04m

$238

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 5/15

12:07 pm-10:57 pm

1 stop11h 50m

Des Moines

Mon 5/18

6:48 pm-4:57 pm

1 stop21h 09m

$241

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Wed 5/6

6:41 pm-3:15 pm

1 stop21h 34m

Des Moines

Sun 5/10

7:00 am-1:40 pm

1 stop29h 40m

$243

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 6/25

9:51 am-10:58 pm

2 stops14h 07m

Des Moines

Sun 6/28

5:02 pm-12:54 pm

1 stop18h 52m

$244

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Orlando to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Orlando and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in October, then November is your next best option. Flight prices from Orlando to Des Moines during November average around $158.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Orlando to Des Moines is on a Tuesday. Travelers who choose to depart for Des Moines on a Tuesday will often find tickets for as low as $139. Flights from Orlando to Des Moines on a Monday will generally be more expensive and average around $338. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Orlando to Des Moines in the evening for as low as $158. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $254. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Orlando to Des Moines flight route?

Fly from Orlando Sanford Intl to Des Moines for the best Orlando - Des Moines flight prices

What cabin class options are available on Orlando to Des Moines flights?

There is only 1 cabin class available to choose from on Orlando to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Orlando to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Orlando to Des Moines.

How have Orlando to Des Moines flight prices changed over time?

As of April 2026, prices for Orlando to Des Moines flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Orlando to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando to Des Moines (ORL to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando to Des Moines

Best Price Found

$144

Fastest flight time

5h 56m

Direct flights

None
The best one-way flight to Des Moines from Orlando in the past 72 hours is $144. The best round-trip flight deal from Orlando to Des Moines found on momondo in the last 72 hours is $232.
The fastest flight from Orlando to Des Moines takes 5h 56m
There are no direct flights from Orlando to Des Moines. There are no popular flight routes from Orlando to Des Moines.
Search flight deals

Frequently asked questions about flying from Orlando to Des Moines

  • How far is Orlando to Des Moines by plane?

    Des Moines is 1133.6 mi away from Orlando. Typically, this will take 5h 56m by plane in normal conditions.

  • When did momondo last update prices for flights from Orlando to Des Moines Airport?

    Prices for flights from Orlando to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Orlando to Des Moines Airport?

  • How old do you have to be to fly from Orlando to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando to Des Moines?

  • What is the most popular airline from Orlando to Des Moines?

Best airlines flying from Orlando to Des Moines

Compare and see reviews for airlines that fly from Orlando to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $90Free CancellationRating
5.6
2,981 reviews
Search Frontier flights
Allegiant AirPriceFrom $106Free CancellationRating
7.3
707 reviews
Search Allegiant Air flights
DeltaPriceFrom $266Free CancellationRating
7.9
8,435 reviews
Search Delta flights
American AirlinesPriceFrom $274Free CancellationRating
7.1
11,655 reviews
Search American Airlines flights

  • Allegiant Air Flights From Orlando to Des Moines

    Allegiant Air is one of the most popular airlines flying from Orlando to Des Moines, operating 2 flights/week on average for this route. A good Allegiant Air flight deal for Orlando to Des Moines starts from $106 round-trip, up to an average price of $245. Our users have rated Allegiant Air at 7.3/10.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Des Moines?

Finding the right flight to Des Moines from Orlando is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Orlando to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Orlando which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Orlando to Des Moines?

Once all potential Orlando to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Orlando to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Orlando to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Des Moines trip

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