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Cheap flights from Orlando to Des Moines from $103

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando to Des Moines departing on 9/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Orlando to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
11:05 am - 7:57 pmMCO  Orlando-DSM Des Moines
9h 52m1 stop Philadelphia
Multiple Airlines Logo
1:58 pm - 7:58 amDSM  Des Moines-MCO Orlando
17h 00m1 stop Philadelphia
$191Multiple Airlines
Thu, Sep 24 - Sun, Sep 27
Multiple Airlines Logo
9:05 am - 7:57 pmMCO  Orlando-DSM Des Moines
11h 52m1 stop Philadelphia
Multiple Airlines Logo
1:58 pm - 6:14 pmDSM  Des Moines-MCO Orlando
27h 16m1 stop Philadelphia
$204Multiple Airlines
Thu, Sep 17 - Sun, Sep 20
Frontier Logo
5:35 am - 1:34 pmMCO  Orlando-DSM Des Moines
8h 59m1 stop Denver Intl
Frontier Logo
2:19 pm - 5:38 amDSM  Des Moines-MCO Orlando
14h 19m1 stop Denver Intl
$262Frontier
Fri, Aug 28 - Mon, Aug 31
Frontier Logo
5:35 am - 1:34 pmMCO  Orlando-DSM Des Moines
8h 59m1 stop Denver Intl
Frontier Logo
2:19 pm - 5:38 amDSM  Des Moines-MCO Orlando
14h 19m1 stop Denver Intl
$269Frontier
Fri, Aug 28 - Mon, Aug 31
American Airlines Logo
1:30 pm - 6:41 pmMCO  Orlando-DSM Des Moines
6h 11m1 stop Charlotte Douglas
American Airlines Logo
10:30 am - 5:09 pmDSM  Des Moines-MCO Orlando
5h 39m1 stop Chicago O'Hare Intl
$343American Airlines
Tue, Sep 1 - Wed, Sep 2
Delta Logo
9:15 am - 2:13 pmMCO  Orlando-DSM Des Moines
5h 58m1 stop Atlanta Hartsfield-Jackson
Delta Logo
2:43 pm - 10:10 pmDSM  Des Moines-MCO Orlando
6h 27m1 stop Minneapolis St Paul
$385Delta
Mon, Nov 23 - Tue, Dec 1
Delta Logo
9:45 am - 2:13 pmMCO  Orlando-DSM Des Moines
5h 28m1 stop Atlanta Hartsfield-Jackson
Delta Logo
10:21 am - 7:19 pmDSM  Des Moines-MCO Orlando
7h 58m1 stop Detroit Metropolitan Wayne County
$385Delta
Mon, Nov 23 - Wed, Dec 2
American Airlines Logo
7:05 am - 12:31 pmMCO  Orlando-DSM Des Moines
6h 26m1 stop Philadelphia
American Airlines Logo
1:30 pm - 7:44 pmDSM  Des Moines-MCO Orlando
5h 14m1 stop Charlotte Douglas
$385American Airlines
Wed, Sep 23 - Mon, Sep 28
United Airlines Logo
7:15 am - 12:34 pmMCO  Orlando-DSM Des Moines
6h 19m1 stop Chicago O'Hare Intl
United Airlines Logo
3:11 pm - 10:07 pmDSM  Des Moines-MCO Orlando
5h 56m1 stop Chicago O'Hare Intl
$385United Airlines
Thu, Sep 24 - Mon, Sep 28
United Airlines Logo
7:40 am - 12:18 pmMCO  Orlando-DSM Des Moines
5h 38m1 stop Chicago O'Hare Intl
United Airlines Logo
1:35 pm - 11:25 pmDSM  Des Moines-MCO Orlando
8h 50m1 stop Denver Intl
$429United Airlines
Sat, Sep 5 - Fri, Sep 11

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Frontier flights from Orlando to Des Moines

Our best Frontier deals on Orlando to Des Moines flight tickets
Frontier
Aug 28
MCO5:35 amOrlando
8h 59m
1 stop
DSM1:34 pmDes Moines
Aug 31
DSM2:19 pmDes Moines
14h 19m
1 stop
MCO5:38 amOrlando
$262
Frontier
Aug 28
MCO5:35 amOrlando
8h 59m
1 stop
DSM1:34 pmDes Moines
Aug 31
DSM2:19 pmDes Moines
14h 19m
1 stop
MCO5:38 amOrlando
$269
Frontier
Sep 11
MCO1:28 pmOrlando
7h 05m
1 stop
DSM7:33 pmDes Moines
Sep 13
DSM11:29 amDes Moines
12h 30m
1 stop
MCO12:59 amOrlando
$275

Southwest flights from Orlando to Des Moines

Our best Southwest deals on Orlando to Des Moines flight tickets
Southwest
Nov 2
MCO7:10 amOrlando
12h 25m
1 stop
DSM6:35 pmDes Moines
Nov 6
DSM1:50 pmDes Moines
10h 20m
2 stops
MCO1:10 amOrlando
$332
Southwest
Sep 14
MCO6:20 amOrlando
8h 25m
1 stop
DSM1:45 pmDes Moines
Sep 30
DSM7:15 amDes Moines
10h 55m
1 stop
MCO7:10 pmOrlando
$365
Southwest
Sep 14
MCO3:00 pmOrlando
8h 15m
2 stops
DSM10:15 pmDes Moines
Sep 30
DSM6:10 amDes Moines
7h 50m
2 stops
MCO3:00 pmOrlando
$370

momondo Fare Finder

 
Customize your flight search to find flights from Orlando to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Orlando to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 9/24

11:05 am-7:57 pm

1 stop9h 52m

Des Moines

Sun 9/27

1:58 pm-7:58 am

1 stop17h 00m

$191

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 9/17

9:05 am-7:57 pm

1 stop11h 52m

Des Moines

Sun 9/20

1:58 pm-6:14 pm

1 stop27h 16m

$204

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Fri 8/28

5:35 am-1:34 pm

1 stop8h 59m

Des Moines

Mon 8/31

2:19 pm-5:38 am

1 stop14h 19m

$262

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Fri 8/28

5:35 am-1:34 pm

1 stop8h 59m

Des Moines

Mon 8/31

2:19 pm-5:38 am

1 stop14h 19m

$269

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Tue 9/1

1:30 pm-6:41 pm

1 stop6h 11m

Des Moines

Wed 9/2

10:30 am-5:09 pm

1 stop5h 39m

$343

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Mon 11/23

9:15 am-2:13 pm

1 stop5h 58m

Des Moines

Tue 12/1

2:43 pm-10:10 pm

1 stop6h 27m

$385

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Mon 11/23

9:45 am-2:13 pm

1 stop5h 28m

Des Moines

Wed 12/2

10:21 am-7:19 pm

1 stop7h 58m

$385
Quickest round-trip

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Wed 9/23

7:05 am-12:31 pm

1 stop6h 26m

Des Moines

Mon 9/28

1:30 pm-7:44 pm

1 stop5h 14m

$385

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 9/24

7:15 am-12:34 pm

1 stop6h 19m

Des Moines

Mon 9/28

3:11 pm-10:07 pm

1 stop5h 56m

$385

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Sat 9/5

7:40 am-12:18 pm

1 stop5h 38m

Des Moines

Fri 9/11

1:35 pm-11:25 pm

1 stop8h 50m

$429

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Orlando to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Orlando and Des Moines?

Prices are currently typical for flights on this route.

Typical prices usually range from $188 to $397.
The lowest price recently found on this route was $191.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in March, then November is your next best option. Flight prices from Orlando to Des Moines during November average around $173.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Orlando to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $157. Flights from Orlando to Des Moines on a Monday will generally be more expensive and average around $394. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Orlando to Des Moines in the afternoon for as low as $153. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $394. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Orlando to Des Moines flight route?

Fly from Orlando Sanford Intl to Des Moines for the best Orlando - Des Moines flight prices

What cabin class options are available on Orlando to Des Moines flights?

There is only 1 cabin class available to choose from on Orlando to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Orlando to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Orlando to Des Moines.

How have Orlando to Des Moines flight prices changed over time?

As of August 2026, prices for Orlando to Des Moines flights are approximately 89% more expensive when compared to flights at the same time last year.

When to book flights from Orlando to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando to Des Moines (ORL to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando to Des Moines

Best Price Found

$144

Fastest flight time

5h 20m

Direct flights

None
The best one-way flight to Des Moines from Orlando in the past 72 hours is $144. The best round-trip flight deal from Orlando to Des Moines found on momondo in the last 72 hours is $242.
The fastest flight from Orlando to Des Moines takes 5h 20m
There are no direct flights from Orlando to Des Moines. There are no popular flight routes from Orlando to Des Moines.
Search flight deals

Frequently asked questions about flying from Orlando to Des Moines

  • How far is Orlando to Des Moines by plane?

    Des Moines is 1133.6 mi away from Orlando. Typically, this will take 5h 20m by plane in normal conditions.

  • When did momondo last update prices for flights from Orlando to Des Moines Airport?

    Prices for flights from Orlando to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Orlando to Des Moines Airport?

  • How old do you have to be to fly from Orlando to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando to Des Moines?

  • What is the most popular airline from Orlando to Des Moines?

Best airlines flying from Orlando to Des Moines

Compare and see reviews for airlines that fly from Orlando to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $90Free CancellationRating
5.6
2,715 reviews
Search Frontier flights
Allegiant AirPriceFrom $148Free CancellationRating
7.3
679 reviews
Search Allegiant Air flights
DeltaPriceFrom $266Free CancellationRating
7.8
8,496 reviews
Search Delta flights
American AirlinesPriceFrom $337Free CancellationRating
7.1
11,896 reviews
Search American Airlines flights
United AirlinesPriceFrom $497Free CancellationRating
7.4
10,099 reviews
Search United Airlines flights

  • Allegiant Air Flights From Orlando to Des Moines

    Allegiant Air is one of the most popular airlines flying from Orlando to Des Moines, operating 1 flight/week on average for this route. A good Allegiant Air flight deal for Orlando to Des Moines starts from $148 round-trip, up to an average price of $244. Our users have rated Allegiant Air at 7.3/10.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Urbandale
Newton
Osceola
Johnston
Boone
Oskaloosa
Norwalk
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Des Moines?

Finding the right flight to Des Moines from Orlando is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Orlando to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Orlando which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Orlando to Des Moines?

Once all potential Orlando to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Orlando to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Orlando to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Des Moines trip

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