Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Orlando to Des Moines from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando to Des Moines departing on 5/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Orlando to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:45 pm - 4:59 pm
MCO
-
DSM
20h 14m
1 stop
Multiple Airlines Logo
12:56 pm - 1:52 pm
DSM
-
MCO
23h 56m
1 stop
$196Multiple Airlines
Thu, Jun 4 - Mon, Jun 8
Multiple Airlines Logo
9:45 pm - 9:09 pm
MCO
-
DSM
24h 24m
1 stop
Multiple Airlines Logo
9:51 pm - 8:22 pm
DSM
-
MCO
21h 31m
1 stop
$197Multiple Airlines
Thu, May 21 - Fri, May 29
Multiple Airlines Logo
3:10 pm - 1:20 pm
MCO
-
DSM
23h 10m
1 stop
Multiple Airlines Logo
9:51 pm - 9:52 am
DSM
-
MCO
11h 01m
1 stop
$203Multiple Airlines
Wed, May 27 - Fri, May 29
Multiple Airlines Logo
10:50 am - 9:09 pm
MCO
-
DSM
11h 19m
1 stop
Multiple Airlines Logo
9:51 pm - 8:22 pm
DSM
-
MCO
21h 31m
1 stop
$208Multiple Airlines
Fri, May 22 - Fri, May 29
Multiple Airlines Logo
3:10 pm - 1:20 pm
MCO
-
DSM
23h 10m
1 stop
Multiple Airlines Logo
9:51 pm - 8:22 pm
DSM
-
MCO
21h 31m
1 stop
$209Multiple Airlines
Sat, May 23 - Fri, May 29
Multiple Airlines Logo
6:32 pm - 10:07 am
MCO
-
DSM
16h 35m
1 stop
Multiple Airlines Logo
5:30 pm - 11:29 pm
DSM
-
MCO
4h 59m
1 stop
$211Multiple Airlines
Wed, Jul 15 - Mon, Jul 20
Multiple Airlines Logo
3:10 pm - 1:20 pm
MCO
-
DSM
23h 10m
1 stop
Multiple Airlines Logo
9:51 pm - 1:52 pm
DSM
-
MCO
15h 01m
1 stop
$213Multiple Airlines
Wed, May 27 - Mon, Jun 1
Multiple Airlines Logo
6:32 pm - 4:40 pm
MCO
-
DSM
23h 08m
1 stop
Multiple Airlines Logo
5:30 pm - 11:29 pm
DSM
-
MCO
4h 59m
1 stop
$216Multiple Airlines
Thu, Jul 16 - Mon, Jul 20
Multiple Airlines Logo
7:56 am - 10:58 pm
MCO
-
DSM
16h 02m
2 stops
Multiple Airlines Logo
12:56 pm - 1:52 pm
DSM
-
MCO
23h 56m
1 stop
$217Multiple Airlines
Thu, Jun 4 - Mon, Jun 8
Frontier Logo
6:00 am - 1:31 pm
MCO
-
DSM
8h 31m
1 stop
Frontier Logo
2:16 pm - 11:43 am
DSM
-
MCO
20h 27m
1 stop
$221Frontier
Wed, May 27 - Wed, Jun 3

American Airlines flights from Orlando to Des Moines

Our best American Airlines deals on Orlando to Des Moines flight tickets
American Airlines
Jun 4
MCO8:00 amOrlando
5h 52m
1 stop
DSM12:52 pmDes Moines
Jun 9
DSM1:33 pmDes Moines
6h 24m
1 stop
MCO8:57 pmOrlando
$378
American Airlines
May 13
MCO8:06 amOrlando
6h 05m
1 stop
DSM1:11 pmDes Moines
May 17
DSM2:24 pmDes Moines
7h 25m
1 stop
MCO10:49 pmOrlando
$517
American Airlines
May 13
MCO6:01 pmOrlando
6h 58m
1 stop
DSM11:59 pmDes Moines
May 17
DSM2:24 pmDes Moines
7h 25m
1 stop
MCO10:49 pmOrlando
$533

United Airlines flights from Orlando to Des Moines

Our best United Airlines deals on Orlando to Des Moines flight tickets
United Airlines
May 12
MCO9:02 amOrlando
6h 22m
1 stop
DSM2:24 pmDes Moines
May 19
DSM11:40 amDes Moines
5h 50m
1 stop
MCO6:30 pmOrlando
$427
United Airlines
May 12
MCO11:51 amOrlando
9h 25m
2 stops
DSM8:16 pmDes Moines
May 19
DSM11:40 amDes Moines
5h 50m
1 stop
MCO6:30 pmOrlando
$433
United Airlines
May 13
MCO9:32 amOrlando
12h 51m
2 stops
DSM9:23 pmDes Moines
May 18
DSM3:20 pmDes Moines
5h 35m
1 stop
MCO9:55 pmOrlando
$554

momondo Fare Finder

 
Customize your flight search to find flights from Orlando to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Orlando to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 6/4

9:45 pm-4:59 pm

1 stop20h 14m

Des Moines

Mon 6/8

12:56 pm-1:52 pm

1 stop23h 56m

$196

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 5/21

9:45 pm-9:09 pm

1 stop24h 24m

Des Moines

Fri 5/29

9:51 pm-8:22 pm

1 stop21h 31m

$197

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Wed 5/27

3:10 pm-1:20 pm

1 stop23h 10m

Des Moines

Fri 5/29

9:51 pm-9:52 am

1 stop11h 01m

$203

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 5/22

10:50 am-9:09 pm

1 stop11h 19m

Des Moines

Fri 5/29

9:51 pm-8:22 pm

1 stop21h 31m

$208

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Sat 5/23

3:10 pm-1:20 pm

1 stop23h 10m

Des Moines

Fri 5/29

9:51 pm-8:22 pm

1 stop21h 31m

$209
Quickest round-trip

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Wed 7/15

6:32 pm-10:07 am

1 stop16h 35m

Des Moines

Mon 7/20

5:30 pm-11:29 pm

1 stop4h 59m

$211

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Wed 5/27

3:10 pm-1:20 pm

1 stop23h 10m

Des Moines

Mon 6/1

9:51 pm-1:52 pm

1 stop15h 01m

$213

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 7/16

6:32 pm-4:40 pm

1 stop23h 08m

Des Moines

Mon 7/20

5:30 pm-11:29 pm

1 stop4h 59m

$216

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 6/4

7:56 am-10:58 pm

2 stops16h 02m

Des Moines

Mon 6/8

12:56 pm-1:52 pm

1 stop23h 56m

$217

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Wed 5/27

6:00 am-1:31 pm

1 stop8h 31m

Des Moines

Wed 6/3

2:16 pm-11:43 am

1 stop20h 27m

$221

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Orlando to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Orlando and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in May, then September is your next best option. Flight prices from Orlando to Des Moines during September average around $80.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Orlando to Des Moines is on a Tuesday. Travelers who choose to depart for Des Moines on a Tuesday will often find tickets for as low as $139. Flights from Orlando to Des Moines on a Monday will generally be more expensive and average around $338. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Orlando to Des Moines in the evening for as low as $158. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $254. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Orlando to Des Moines flight route?

Fly from Orlando Sanford Intl to Des Moines for the best Orlando - Des Moines flight prices

Can stopping save me money on Orlando to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Orlando to Des Moines.

How have Orlando to Des Moines flight prices changed over time?

As of April 2026, prices for Orlando to Des Moines flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Orlando to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando to Des Moines (ORL to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando to Des Moines

Best Price Found

$128

Fastest flight time

5h 37m

Direct flights

None
The best one-way flight to Des Moines from Orlando in the past 72 hours is $128. The best round-trip flight deal from Orlando to Des Moines found on momondo in the last 72 hours is $218.
The fastest flight from Orlando to Des Moines takes 5h 37m
There are no direct flights from Orlando to Des Moines. There are no popular flight routes from Orlando to Des Moines.
Search flight deals

Frequently asked questions about flying from Orlando to Des Moines

  • How far is Orlando to Des Moines by plane?

    Des Moines is 1133.6 mi away from Orlando. Typically, this will take 5h 37m by plane in normal conditions.

  • When did momondo last update prices for flights from Orlando to Des Moines Airport?

    Prices for flights from Orlando to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Orlando to Des Moines Airport?

  • How old do you have to be to fly from Orlando to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando to Des Moines?

  • What is the most popular airline from Orlando to Des Moines?

Best airlines flying from Orlando to Des Moines

Compare and see reviews for airlines that fly from Orlando to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $90Free CancellationRating
5.6
2,970 reviews
Search Frontier flights
Allegiant AirPriceFrom $106Free CancellationRating
7.3
707 reviews
Search Allegiant Air flights
DeltaPriceFrom $266Free CancellationRating
7.9
8,466 reviews
Search Delta flights
American AirlinesPriceFrom $285Free CancellationRating
7.1
11,680 reviews
Search American Airlines flights

  • Allegiant Air Flights From Orlando to Des Moines

    Allegiant Air is one of the most popular airlines flying from Orlando to Des Moines, operating 1 flight/week on average for this route. A good Allegiant Air flight deal for Orlando to Des Moines starts from $106 round-trip, up to an average price of $245. Our users have rated Allegiant Air at 7.3/10.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Des Moines?

Finding the right flight to Des Moines from Orlando is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Orlando to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Orlando which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Orlando to Des Moines?

Once all potential Orlando to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Orlando to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Orlando to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 5/29
Fri 6/5
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States