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Cheap flights from Orlando to Des Moines from $110

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Orlando to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:12 pm - 2:42 pmMCO  Orlando-DSM Des Moines
18h 30m1 stop Philadelphia
Multiple Airlines Logo
6:25 am - 8:11 pmDSM  Des Moines-MCO Orlando
12h 46m1 stop Nashville Intl
$235Multiple Airlines
Sat, Oct 10 - Mon, Oct 19
Frontier Logo
5:25 pm - 7:33 pmMCO  Orlando-DSM Des Moines
27h 08m1 stop Denver Intl
Frontier Logo
11:29 am - 4:17 pmDSM  Des Moines-MCO Orlando
27h 48m1 stop Denver Intl
$250Frontier
Thu, Sep 17 - Thu, Sep 24
Frontier Logo
1:28 pm - 10:44 amMCO  Orlando-DSM Des Moines
22h 16m1 stop Denver Intl
Frontier Logo
8:30 pm - 12:23 pmDSM  Des Moines-MCO Orlando
14h 53m1 stop Denver Intl
$250Frontier
Sat, Oct 3 - Mon, Oct 5
Multiple Airlines Logo
7:01 am - 7:57 pmMCO  Orlando-DSM Des Moines
13h 56m1 stop Philadelphia
Multiple Airlines Logo
4:59 pm - 5:09 pmDSM  Des Moines-MCO Orlando
23h 10m2 stops Tampa St. Petersburg Atlanta Hartsfield-Jackson
$255Multiple Airlines
Sun, Sep 6 - Mon, Sep 21
American Airlines Logo
7:31 pm - 12:14 amMCO  Orlando-DSM Des Moines
5h 43m1 stop Chicago O'Hare Intl
American Airlines Logo
11:22 am - 5:35 pmDSM  Des Moines-MCO Orlando
5h 13m1 stop Charlotte Douglas
$339American Airlines
Thu, Oct 15 - Wed, Oct 21
American Airlines Logo
3:30 pm - 11:07 pmMCO  Orlando-DSM Des Moines
8h 37m1 stop Dallas/Fort Worth
American Airlines Logo
2:01 pm - 10:55 pmDSM  Des Moines-MCO Orlando
7h 54m1 stop Chicago O'Hare Intl
$339American Airlines
Sat, Oct 10 - Mon, Oct 19
Delta Logo
5:45 pm - 10:37 pmMCO  Orlando-DSM Des Moines
5h 52m1 stop Atlanta Hartsfield-Jackson
Delta Logo
11:00 am - 5:14 pmDSM  Des Moines-MCO Orlando
5h 14m1 stop Minneapolis St Paul
$339Delta
Sat, Sep 5 - Sun, Sep 6
Delta Logo
6:34 am - 2:25 pmMCO  Orlando-DSM Des Moines
8h 51m1 stop Minneapolis St Paul
Delta Logo
10:22 am - 5:06 pmDSM  Des Moines-MCO Orlando
5h 44m1 stop Detroit Metropolitan Wayne County
$339Delta
Sat, Oct 24 - Mon, Oct 26
United Airlines Logo
7:15 am - 12:34 pmMCO  Orlando-DSM Des Moines
6h 19m1 stop Chicago O'Hare Intl
United Airlines Logo
11:27 am - 7:34 pmDSM  Des Moines-MCO Orlando
7h 07m1 stop Chicago O'Hare Intl
$339United Airlines
Thu, Oct 8 - Tue, Oct 13
United Airlines Logo
9:10 am - 2:15 pmMCO  Orlando-DSM Des Moines
6h 05m1 stop Chicago O'Hare Intl
United Airlines Logo
11:27 am - 6:28 pmDSM  Des Moines-MCO Orlando
6h 01m1 stop Chicago O'Hare Intl
$339United Airlines
Thu, Oct 8 - Wed, Oct 14

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Frontier flights from Orlando to Des Moines

Our best Frontier deals on Orlando to Des Moines flight tickets
Frontier
Sep 17
MCO5:25 pmOrlando
27h 08m
1 stop
DSM7:33 pmDes Moines
Sep 24
DSM11:29 amDes Moines
27h 48m
1 stop
MCO4:17 pmOrlando
$250
Frontier
Oct 16
MCO5:55 amOrlando
14h 35m
1 stop
DSM7:30 pmDes Moines
Oct 19
DSM8:25 pmDes Moines
27h 18m
1 stop
MCO12:43 amOrlando
$264
Frontier
Sep 25
MCO1:28 pmOrlando
7h 05m
1 stop
DSM7:33 pmDes Moines
Sep 28
DSM8:30 pmDes Moines
14h 53m
1 stop
MCO12:23 pmOrlando
$265

United Airlines flights from Orlando to Des Moines

Our best United Airlines deals on Orlando to Des Moines flight tickets
United Airlines
Oct 16
MCO9:10 amOrlando
6h 05m
1 stop
DSM2:15 pmDes Moines
Oct 20
DSM6:00 amDes Moines
7h 56m
1 stop
MCO2:56 pmOrlando
$362
United Airlines
Sep 6
MCO4:21 pmOrlando
6h 02m
1 stop
DSM9:23 pmDes Moines
Sep 10
DSM5:45 amDes Moines
9h 05m
1 stop
MCO3:50 pmOrlando
$429
United Airlines
Sep 6
MCO12:33 pmOrlando
9h 50m
2 stops
DSM9:23 pmDes Moines
Sep 12
DSM1:35 pmDes Moines
8h 50m
1 stop
MCO11:25 pmOrlando
$434

momondo Fare Finder

 
Use the filters below to find and compare flights from Orlando to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Sat 10/10

9:12 pm-2:42 pm

1 stop18h 30m

Des Moines

Mon 10/19

6:25 am-8:11 pm

1 stop12h 46m

$235

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 9/17

5:25 pm-7:33 pm

1 stop27h 08m

Des Moines

Thu 9/24

11:29 am-4:17 pm

1 stop27h 48m

$250

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Sat 10/3

1:28 pm-10:44 am

1 stop22h 16m

Des Moines

Mon 10/5

8:30 pm-12:23 pm

1 stop14h 53m

$250

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Sun 9/6

7:01 am-7:57 pm

1 stop13h 56m

Des Moines

Mon 9/21

4:59 pm-5:09 pm

2 stops23h 10m

$255
Quickest round-trip

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 10/15

7:31 pm-12:14 am

1 stop5h 43m

Des Moines

Wed 10/21

11:22 am-5:35 pm

1 stop5h 13m

$339

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Sat 10/10

3:30 pm-11:07 pm

1 stop8h 37m

Des Moines

Mon 10/19

2:01 pm-10:55 pm

1 stop7h 54m

$339

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Sat 9/5

5:45 pm-10:37 pm

1 stop5h 52m

Des Moines

Sun 9/6

11:00 am-5:14 pm

1 stop5h 14m

$339

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Sat 10/24

6:34 am-2:25 pm

1 stop8h 51m

Des Moines

Mon 10/26

10:22 am-5:06 pm

1 stop5h 44m

$339

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 10/8

7:15 am-12:34 pm

1 stop6h 19m

Des Moines

Tue 10/13

11:27 am-7:34 pm

1 stop7h 07m

$339

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 10/8

9:10 am-2:15 pm

1 stop6h 05m

Des Moines

Wed 10/14

11:27 am-6:28 pm

1 stop6h 01m

$339

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Orlando to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Orlando and Des Moines?

Prices are currently low for flights on this route.

Typical prices usually range from $273 to $432.
The lowest price recently found on this route was $235.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in March, then November is your next best option. Flight prices from Orlando to Des Moines during November average around $173.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Orlando to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $157. Flights from Orlando to Des Moines on a Monday will generally be more expensive and average around $394. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Orlando to Des Moines in the afternoon for as low as $153. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $394. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Orlando to Des Moines flight route?

Fly from Orlando Sanford Intl to Des Moines for the best Orlando - Des Moines flight prices

What cabin class options are available on Orlando to Des Moines flights?

There is only 1 cabin class available to choose from on Orlando to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Orlando to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Orlando to Des Moines.

How have Orlando to Des Moines flight prices changed over time?

As of August 2026, prices for Orlando to Des Moines flights are approximately 89% more expensive when compared to flights at the same time last year.

When to book flights from Orlando to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando to Des Moines (ORL to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando to Des Moines

Best Price Found

$110

Fastest flight time

4h 46m

Direct flights

None
The best one-way flight to Des Moines from Orlando in the past 72 hours is $110. The best round-trip flight deal from Orlando to Des Moines found on momondo in the last 72 hours is $235.
The fastest flight from Orlando to Des Moines takes 4h 46m
There are no direct flights from Orlando to Des Moines. There are no popular flight routes from Orlando to Des Moines.
Search flight deals

Frequently asked questions about flying from Orlando to Des Moines

  • How far is Orlando to Des Moines by plane?

    Des Moines is 1133.6 mi away from Orlando. Typically, this will take 4h 46m by plane in normal conditions.

  • When did momondo last update prices for flights from Orlando to Des Moines Airport?

    Prices for flights from Orlando to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Orlando to Des Moines Airport?

  • How old do you have to be to fly from Orlando to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando to Des Moines?

  • What is the most popular airline from Orlando to Des Moines?

Best airlines flying from Orlando to Des Moines

Compare and see reviews for airlines that fly from Orlando to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $90Free CancellationRating
5.6
2,648 reviews
Search Frontier flights
Allegiant AirPriceFrom $148Free CancellationRating
7.3
675 reviews
Search Allegiant Air flights
DeltaPriceFrom $316Free CancellationRating
7.8
8,530 reviews
Search Delta flights
American AirlinesPriceFrom $337Free CancellationRating
7.1
11,990 reviews
Search American Airlines flights
United AirlinesPriceFrom $374Free CancellationRating
7.4
10,120 reviews
Search United Airlines flights

  • Allegiant Air Flights From Orlando to Des Moines

    Allegiant Air is one of the most popular airlines flying from Orlando to Des Moines, operating 1 flight/week on average for this route. A good Allegiant Air flight deal for Orlando to Des Moines starts from $148 round-trip, up to an average price of $246. Our users have rated Allegiant Air at 7.3/10.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Urbandale
Newton
Osceola
Boone
Johnston
Oskaloosa
Norwalk
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Des Moines?

Finding the right flight to Des Moines from Orlando is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Orlando to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Orlando which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Orlando to Des Moines?

Once all potential Orlando to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Orlando to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Orlando to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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