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Cheap flights from Orlando to Des Moines from $49

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando to Des Moines departing on 1/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Orlando to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:00 am - 10:19 amMCO-DSM
3h 19mnonstop
Frontier Logo
11:14 am - 3:14 pmDSM-MCO
3h 00mnonstop
$97Frontier
Find Deal
Tue, Dec 23 - Tue, Dec 30
Frontier Logo
6:00 am - 7:03 pmMCO-DSM
14h 03m1 stop
Frontier Logo
7:58 pm - 5:31 amDSM-MCO
8h 33m1 stop
$128Frontier
Find Deal
Mon, Dec 8 - Fri, Dec 12
Frontier Logo
6:00 am - 7:03 pmMCO-DSM
14h 03m1 stop
Frontier Logo
7:58 pm - 5:31 amDSM-MCO
8h 33m1 stop
$136Frontier
Find Deal
Fri, Dec 5 - Mon, Dec 8
Multiple Airlines Logo
6:45 am - 2:58 pmMCO-DSM
9h 13m1 stop
Multiple Airlines Logo
7:58 pm - 2:27 pmDSM-MCO
17h 29m2 stops
$194Multiple Airlines
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Fri, Dec 12 - Mon, Dec 15
Multiple Airlines Logo
6:00 am - 7:03 pmMCO-DSM
14h 03m1 stop
Multiple Airlines Logo
8:00 am - 2:13 pmDSM-MCO
29h 13m1 stop
$197Multiple Airlines
Find Deal
Mon, Dec 8 - Fri, Dec 12
Delta Logo
7:00 am - 1:31 pmMCO-DSM
7h 31m1 stop
Delta Logo
3:30 pm - 12:08 amDSM-MCO
7h 38m1 stop
$237Delta
Find Deal
Mon, Dec 8 - Sat, Dec 13
American Airlines Logo
7:00 am - 12:46 pmMCO-DSM
6h 46m1 stop
American Airlines Logo
2:01 pm - 10:00 pmDSM-MCO
6h 59m1 stop
$286American Airlines
Find Deal
Wed, Feb 11 - Sun, Feb 15
Delta Logo
9:00 am - 1:31 pmMCO-DSM
5h 31m1 stop
Delta Logo
11:23 am - 7:50 pmDSM-MCO
7h 27m1 stop
$287Delta
Find Deal
Tue, Dec 2 - Sat, Dec 13
Southwest Logo
2:45 pm - 9:35 pmMCO-DSM
7h 50m2 stops
Southwest Logo
6:25 am - 11:45 amDSM-MCO
4h 20m1 stop
$327Southwest
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Mon, Dec 8 - Sat, Dec 13
Southwest Logo
4:20 pm - 11:35 pmMCO-DSM
8h 15m2 stops
Southwest Logo
8:20 am - 6:25 pmDSM-MCO
9h 05m2 stops
$332Southwest
Find Deal
Fri, Dec 12 - Mon, Dec 15

Frontier flights from Orlando to Des Moines

Our best Frontier deals on Orlando to Des Moines flight tickets
Frontier
Dec 23
MCO8:00 amOrlando
3h 19m
DSM10:19 amDes Moines
Dec 30
DSM11:14 amDes Moines
3h 00m
MCO3:14 pmOrlando
$97
Find similar
Frontier
Dec 8
MCO6:00 amOrlando
14h 03m
1 stop
DSM7:03 pmDes Moines
Dec 12
DSM7:58 pmDes Moines
8h 33m
1 stop
MCO5:31 amOrlando
$128
Find similar
Frontier
Dec 5
MCO6:00 amOrlando
14h 03m
1 stop
DSM7:03 pmDes Moines
Dec 8
DSM7:58 pmDes Moines
8h 33m
1 stop
MCO5:31 amOrlando
$136
Find similar

United Airlines flights from Orlando to Des Moines

Our best United Airlines deals on Orlando to Des Moines flight tickets
United Airlines
Nov 18
MCO3:31 pmOrlando
9h 13m
1 stop
DSM11:44 pmDes Moines
Nov 20
DSM8:02 amDes Moines
5h 49m
1 stop
MCO2:51 pmOrlando
$493
Find similar
United Airlines
Nov 19
MCO9:00 amOrlando
6h 11m
1 stop
DSM2:11 pmDes Moines
Nov 23
DSM11:26 amDes Moines
5h 35m
1 stop
MCO6:01 pmOrlando
$573
Find similar
United Airlines
Nov 19
MCO7:05 amOrlando
10h 07m
2 stops
DSM4:12 pmDes Moines
Nov 23
DSM11:26 amDes Moines
5h 35m
1 stop
MCO6:01 pmOrlando
$578
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Orlando to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Orlando to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Tue 12/23

8:00 am-10:19 am

Nonstop3h 19m

Des Moines

Tue 12/30

11:14 am-3:14 pm

Nonstop3h 00m

$97

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Mon 12/8

6:00 am-7:03 pm

1 stop14h 03m

Des Moines

Fri 12/12

7:58 pm-5:31 am

1 stop8h 33m

$128

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 12/5

6:00 am-7:03 pm

1 stop14h 03m

Des Moines

Mon 12/8

7:58 pm-5:31 am

1 stop8h 33m

$136

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 12/12

6:45 am-2:58 pm

1 stop9h 13m

Des Moines

Mon 12/15

7:58 pm-2:27 pm

2 stops17h 29m

$194

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Mon 12/8

6:00 am-7:03 pm

1 stop14h 03m

Des Moines

Fri 12/12

8:00 am-2:13 pm

1 stop29h 13m

$197

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Mon 12/8

7:00 am-1:31 pm

1 stop7h 31m

Des Moines

Sat 12/13

3:30 pm-12:08 am

1 stop7h 38m

$237

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Wed 2/11

7:00 am-12:46 pm

1 stop6h 46m

Des Moines

Sun 2/15

2:01 pm-10:00 pm

1 stop6h 59m

$286

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Tue 12/2

9:00 am-1:31 pm

1 stop5h 31m

Des Moines

Sat 12/13

11:23 am-7:50 pm

1 stop7h 27m

$287

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Mon 12/8

2:45 pm-9:35 pm

2 stops7h 50m

Des Moines

Sat 12/13

6:25 am-11:45 am

1 stop4h 20m

$327

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 12/12

4:20 pm-11:35 pm

2 stops8h 15m

Des Moines

Mon 12/15

8:20 am-6:25 pm

2 stops9h 05m

$332

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Orlando to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Orlando and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then April is your next best option. Flight prices from Orlando to Des Moines during April average around $180.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Orlando to Des Moines is on a Tuesday. Travelers who choose to depart for Des Moines on a Tuesday will often find tickets for as low as $149. Flights from Orlando to Des Moines on a Saturday will generally be more expensive and average around $292. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Orlando to Des Moines in the afternoon for as low as $168. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $181. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Orlando to Des Moines flight route?

Fly from Orlando Sanford Intl to Des Moines for the best Orlando - Des Moines flight prices

What cabin class options are available on Orlando to Des Moines flights?

There is only 1 cabin class available to choose from on Orlando to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Orlando to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Orlando to Des Moines.

How have Orlando to Des Moines flight prices changed over time?

As of November 2025, prices for Orlando to Des Moines flights are approximately 14% cheaper when compared to flights at the same time last year.

When to book flights from Orlando to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando to Des Moines (ORL to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando to Des Moines

Best Price Found

$66

Fastest flight time

3h 19m

Direct flights

Mon, Wed and Sun

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Orlando in the past 72 hours is $66. The best round-trip flight deal from Orlando to Des Moines found on momondo in the last 72 hours is $150.
The fastest flight from Orlando to Des Moines takes 3h 19m
Direct flights go from Orlando to Des Moines on Monday, Wednesday and Sunday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near Des Moines: Des Moines (DSM)
Search flight deals

  • How far is Orlando to Des Moines by plane?

    Des Moines is 1133.6 mi away from Orlando. Typically, this will take 3h 19m by plane in normal conditions.

  • When did momondo last update prices for flights from Orlando to Des Moines Airport?

    Prices for flights from Orlando to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Orlando to Des Moines Airport?

  • How old do you have to be to fly from Orlando to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents you'll need for your trip to Des Moines Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Des Moines Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando to Des Moines?

  • What is the most popular airline from Orlando to Des Moines?

Best airlines flying from Orlando to Des Moines

Compare and see reviews for airlines that fly from Orlando to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $106Free CancellationRating
7.2
696 reviews
Search Allegiant Air flights
FrontierPriceFrom $111Free CancellationRating
5.8
3,115 reviews
Search Frontier flights
SouthwestPriceFrom $196Free CancellationRating
8.0
4,239 reviews
Search Southwest flights
DeltaPriceFrom $260Free CancellationRating
7.9
8,004 reviews
Search Delta flights
American AirlinesPriceFrom $285Free CancellationRating
7.2
11,039 reviews
Search American Airlines flights

  • Allegiant Air Flights From Orlando to Des Moines

    Allegiant Air is one of the most popular airlines flying from Orlando to Des Moines, operating 1 flight/week on average for this route. A good Allegiant Air flight deal for Orlando to Des Moines starts from $106 round-trip, up to an average price of $190. Our users have rated Allegiant Air at 7.2/10.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Newton
Pella
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Des Moines?

Finding the right flight to Des Moines from Orlando is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Des Moines quick and easy, saving you time and money.

Can I find flights from Orlando to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Orlando which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Orlando to Des Moines?

Once all potential Orlando to Des Moines flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Orlando to Des Moines right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Orlando to Des Moines flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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