Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Orlando Sanford Intl Airport to Knoxville from $48

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando Sanford Intl Airport to Knoxville departing on 9/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Orlando Sanford Intl Airport to Knoxville

Cheap round-trip flights

Allegiant Air Logo
6:40 am - 8:16 amSFB-TYS
1h 36mnonstop
Allegiant Air Logo
9:38 pm - 11:14 pmTYS-SFB
1h 36mnonstop
$93Allegiant Air
Find Deal
Sat, Nov 8 - Fri, Nov 14
Allegiant Air Logo
8:21 am - 9:56 amSFB-TYS
1h 35mnonstop
Allegiant Air Logo
4:32 pm - 6:03 pmTYS-SFB
1h 31mnonstop
$98Allegiant Air
Find Deal
Mon, Oct 20 - Sat, Oct 25
Allegiant Air Logo
9:38 pm - 11:14 pmSFB-TYS
1h 36mnonstop
Allegiant Air Logo
9:35 pm - 11:08 pmTYS-SFB
1h 33mnonstop
$101Allegiant Air
Find Deal
Fri, Nov 14 - Fri, Nov 21
Allegiant Air Logo
9:23 pm - 10:59 pmSFB-TYS
1h 36mnonstop
Allegiant Air Logo
9:27 pm - 11:03 pmTYS-SFB
1h 36mnonstop
$102Allegiant Air
Find Deal
Thu, Nov 6 - Mon, Nov 10
Allegiant Air Logo
7:16 pm - 8:53 pmSFB-TYS
1h 37mnonstop
Allegiant Air Logo
4:53 pm - 6:26 pmTYS-SFB
1h 33mnonstop
$104Allegiant Air
Find Deal
Thu, Nov 20 - Sun, Nov 23
Allegiant Air Logo
6:25 pm - 8:00 pmSFB-TYS
1h 35mnonstop
Allegiant Air Logo
7:10 pm - 8:41 pmTYS-SFB
1h 31mnonstop
$108Allegiant Air
Find Deal
Mon, Oct 27 - Fri, Oct 31
Allegiant Air Logo
9:00 am - 10:35 amSFB-TYS
1h 35mnonstop
Allegiant Air Logo
6:51 pm - 8:22 pmTYS-SFB
1h 31mnonstop
$110Allegiant Air
Find Deal
Sun, Oct 26 - Thu, Oct 30
Allegiant Air Logo
9:38 pm - 11:14 pmSFB-TYS
1h 36mnonstop
Allegiant Air Logo
9:29 pm - 11:05 pmTYS-SFB
1h 36mnonstop
$113Allegiant Air
Find Deal
Fri, Nov 14 - Mon, Nov 17
Allegiant Air Logo
8:55 am - 10:32 amSFB-TYS
1h 37mnonstop
Allegiant Air Logo
6:30 am - 8:05 amTYS-SFB
1h 35mnonstop
$115Allegiant Air
Find Deal
Fri, Dec 5 - Mon, Dec 8
Allegiant Air Logo
9:38 pm - 11:14 pmSFB-TYS
1h 36mnonstop
Allegiant Air Logo
6:58 pm - 8:33 pmTYS-SFB
1h 35mnonstop
$117Allegiant Air
Find Deal
Fri, Nov 7 - Sun, Nov 9

Allegiant Air flights from Orlando Sanford Intl Airport to Knoxville

Our best Allegiant Air deals on Orlando Sanford Intl Airport to Knoxville flight tickets
Allegiant Air
Nov 8
SFB6:40 amOrlando Sanford Intl
1h 36m
TYS8:16 amKnoxville McGhee Tyson
Nov 14
TYS9:38 pmKnoxville McGhee Tyson
1h 36m
SFB11:14 pmOrlando Sanford Intl
$93
Find similar
Allegiant Air
Oct 20
SFB8:21 amOrlando Sanford Intl
1h 35m
TYS9:56 amKnoxville McGhee Tyson
Oct 25
TYS4:32 pmKnoxville McGhee Tyson
1h 31m
SFB6:03 pmOrlando Sanford Intl
$98
Find similar
Allegiant Air
Nov 14
SFB9:38 pmOrlando Sanford Intl
1h 36m
TYS11:14 pmKnoxville McGhee Tyson
Nov 21
TYS9:35 pmKnoxville McGhee Tyson
1h 33m
SFB11:08 pmOrlando Sanford Intl
$101
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Orlando Sanford Intl Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Orlando Sanford Intl Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Sat 11/8

6:40 am-8:16 am

Nonstop1h 36m

Knoxville McGhee Tyson

Fri 11/14

9:38 pm-11:14 pm

Nonstop1h 36m

$93

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Mon 10/20

8:21 am-9:56 am

Nonstop1h 35m

Knoxville McGhee Tyson

Sat 10/25

4:32 pm-6:03 pm

Nonstop1h 31m

$98

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Fri 11/14

9:38 pm-11:14 pm

Nonstop1h 36m

Knoxville McGhee Tyson

Fri 11/21

9:35 pm-11:08 pm

Nonstop1h 33m

$101

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Thu 11/6

9:23 pm-10:59 pm

Nonstop1h 36m

Knoxville McGhee Tyson

Mon 11/10

9:27 pm-11:03 pm

Nonstop1h 36m

$102

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Thu 11/20

7:16 pm-8:53 pm

Nonstop1h 37m

Knoxville McGhee Tyson

Sun 11/23

4:53 pm-6:26 pm

Nonstop1h 33m

$104

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Mon 10/27

6:25 pm-8:00 pm

Nonstop1h 35m

Knoxville McGhee Tyson

Fri 10/31

7:10 pm-8:41 pm

Nonstop1h 31m

$108

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Sun 10/26

9:00 am-10:35 am

Nonstop1h 35m

Knoxville McGhee Tyson

Thu 10/30

6:51 pm-8:22 pm

Nonstop1h 31m

$110

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Fri 11/14

9:38 pm-11:14 pm

Nonstop1h 36m

Knoxville McGhee Tyson

Mon 11/17

9:29 pm-11:05 pm

Nonstop1h 36m

$113

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Fri 12/5

8:55 am-10:32 am

Nonstop1h 37m

Knoxville McGhee Tyson

Mon 12/8

6:30 am-8:05 am

Nonstop1h 35m

$115

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Fri 11/7

9:38 pm-11:14 pm

Nonstop1h 36m

Knoxville McGhee Tyson

Sun 11/9

6:58 pm-8:33 pm

Nonstop1h 35m

$117

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Orlando Sanford Intl Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Orlando Sanford Intl Airport, with most prices found around $103. If you aren’t able to travel during the month of August, then book flights to Knoxville from Orlando Sanford Intl Airport during April instead. Flights to Knoxville in April, while not as cheap as those in August, still average around $118.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Orlando Sanford Intl Airport to Knoxville is on a Friday. Travelers who choose to depart for Knoxville on a Friday will often find tickets for as low as $134. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Orlando Sanford Intl Airport to Knoxville for around $159.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Orlando Sanford Intl Airport to Knoxville when you can find flight prices for as low as $131. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $150.

What is the cheapest Orlando Sanford Intl to Knoxville McGhee Tyson flight route?

Fly from Orlando Sanford Intl to Knoxville McGhee Tyson for the best Orlando Sanford Intl - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Orlando Sanford Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $144 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Orlando Sanford Intl Airport for as low as $108 on momondo.

What cabin class options are available on Orlando Sanford Intl to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Orlando Sanford Intl to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Orlando Sanford Intl Airport to Knoxville flight prices changed over time?

As of September 2025, prices for Orlando Sanford Intl Airport to Knoxville flights are approximately 2% more expensive when compared to flights at the same time last year.

When to book flights from Orlando Sanford Intl Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando Sanford Intl Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando Sanford Intl Airport to Knoxville (SFB to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando Sanford Intl Airport to Knoxville

Best Price Found

$58

Fastest flight time

1h 33m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Orlando Sanford Intl Airport in the past 72 hours is $58. The best round-trip flight deal from Orlando Sanford Intl Airport to Knoxville found on momondo in the last 72 hours is $129.
The fastest flight from Orlando Sanford Intl Airport to Knoxville takes 1h 33m
Direct flights go from Orlando Sanford Intl Airport to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Orlando Sanford Intl to Knoxville McGhee Tyson by plane?

    There are 520.0 mi between Orlando Sanford Intl and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 1h 33m.

  • When did momondo last update prices for flights from Orlando Sanford Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Orlando Sanford Intl Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Orlando Sanford Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Orlando Sanford Intl Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando Sanford Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Orlando Sanford Intl Airport to Knoxville?

  • What is the most popular airline from Orlando Sanford Intl Airport to Knoxville?

Best airlines flying from Orlando Sanford Intl Airport to Knoxville

Compare and see reviews for airlines that fly from Orlando Sanford Intl Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $83Free CancellationRating
7.2
699 reviews
Search Allegiant Air flights

  • Allegiant Air Flights From Orlando Sanford Intl Airport to Knoxville

    Allegiant Air flight deals from Orlando Sanford Intl Airport to Knoxville start from $83 round-trip. Over the 2 Allegiant Air flights for this route in a normal week, average airfare is usually $146 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Newport
Lenoir City
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Orlando.

Can I find flights from Orlando to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Orlando with this policy.

How can momondo help me find flights from Orlando to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Orlando. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Orlando to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Orlando are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 10/16
Thu 10/23
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States