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Cheap flights from Orlando Sanford Intl Airport to Knoxville from $53

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando Sanford Intl Airport to Knoxville departing on 4/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Orlando Sanford Intl Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
4:38 pm - 6:18 pm
SFB
-
TYS
1h 40mnonstop
Allegiant Air Logo
9:36 pm - 11:10 pm
TYS
-
SFB
1h 34mnonstop
$113Allegiant Air
Wed, Apr 1 - Thu, Apr 9
Allegiant Air Logo
9:20 pm - 10:59 pm
SFB
-
TYS
1h 39mnonstop
Allegiant Air Logo
9:25 am - 10:59 am
TYS
-
SFB
1h 34mnonstop
$114Allegiant Air
Thu, Mar 26 - Fri, Apr 3
Allegiant Air Logo
6:06 pm - 7:46 pm
SFB
-
TYS
1h 40mnonstop
Allegiant Air Logo
1:59 pm - 3:33 pm
TYS
-
SFB
1h 34mnonstop
$116Allegiant Air
Sat, Apr 4 - Sat, Apr 11
Allegiant Air Logo
2:32 pm - 4:10 pm
SFB
-
TYS
1h 38mnonstop
Allegiant Air Logo
2:19 pm - 3:53 pm
TYS
-
SFB
1h 34mnonstop
$117Allegiant Air
Tue, Jun 2 - Wed, Jun 3
Allegiant Air Logo
9:20 pm - 10:59 pm
SFB
-
TYS
1h 39mnonstop
Allegiant Air Logo
12:02 pm - 1:37 pm
TYS
-
SFB
1h 35mnonstop
$118Allegiant Air
Thu, Mar 26 - Tue, Mar 31
Allegiant Air Logo
9:20 pm - 10:59 pm
SFB
-
TYS
1h 39mnonstop
Allegiant Air Logo
9:46 pm - 11:20 pm
TYS
-
SFB
1h 34mnonstop
$119Allegiant Air
Sun, Mar 29 - Sun, Apr 5
Allegiant Air Logo
9:20 pm - 10:59 pm
SFB
-
TYS
1h 39mnonstop
Allegiant Air Logo
9:46 pm - 11:20 pm
TYS
-
SFB
1h 34mnonstop
$120Allegiant Air
Sun, Mar 29 - Thu, Apr 2
Allegiant Air Logo
9:20 pm - 10:59 pm
SFB
-
TYS
1h 39mnonstop
Allegiant Air Logo
6:55 pm - 8:30 pm
TYS
-
SFB
1h 35mnonstop
$121Allegiant Air
Thu, Mar 26 - Sun, Mar 29
Allegiant Air Logo
9:28 pm - 11:06 pm
SFB
-
TYS
1h 38mnonstop
Allegiant Air Logo
5:00 pm - 6:34 pm
TYS
-
SFB
1h 34mnonstop
$122Allegiant Air
Thu, May 28 - Tue, Jun 2
Allegiant Air Logo
7:06 pm - 8:45 pm
SFB
-
TYS
1h 39mnonstop
Allegiant Air Logo
12:00 pm - 1:34 pm
TYS
-
SFB
1h 34mnonstop
$123Allegiant Air
Sat, Mar 28 - Tue, Apr 7

Allegiant Air flights from Orlando Sanford Intl Airport to Knoxville

Our best Allegiant Air deals on Orlando Sanford Intl Airport to Knoxville flight tickets
Allegiant Air
Apr 1
SFB4:38 pmOrlando Sanford Intl
1h 40m
TYS6:18 pmKnoxville McGhee Tyson
Apr 9
TYS9:36 pmKnoxville McGhee Tyson
1h 34m
SFB11:10 pmOrlando Sanford Intl
$113
Allegiant Air
Mar 26
SFB9:20 pmOrlando Sanford Intl
1h 39m
TYS10:59 pmKnoxville McGhee Tyson
Apr 3
TYS9:25 amKnoxville McGhee Tyson
1h 34m
SFB10:59 amOrlando Sanford Intl
$114
Allegiant Air
Apr 4
SFB6:06 pmOrlando Sanford Intl
1h 40m
TYS7:46 pmKnoxville McGhee Tyson
Apr 11
TYS1:59 pmKnoxville McGhee Tyson
1h 34m
SFB3:33 pmOrlando Sanford Intl
$116

momondo Fare Finder

 
Customize your flight search to find flights from Orlando Sanford Intl Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 9, 2026.
Use the filters below to find and compare flights from Orlando Sanford Intl Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Wed 4/1

4:38 pm-6:18 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Thu 4/9

9:36 pm-11:10 pm

Nonstop1h 34m

$113

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Thu 3/26

9:20 pm-10:59 pm

Nonstop1h 39m

Knoxville McGhee Tyson

Fri 4/3

9:25 am-10:59 am

Nonstop1h 34m

$114

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Sat 4/4

6:06 pm-7:46 pm

Nonstop1h 40m

Knoxville McGhee Tyson

Sat 4/11

1:59 pm-3:33 pm

Nonstop1h 34m

$116
Quickest round-trip

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Tue 6/2

2:32 pm-4:10 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Wed 6/3

2:19 pm-3:53 pm

Nonstop1h 34m

$117

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Thu 3/26

9:20 pm-10:59 pm

Nonstop1h 39m

Knoxville McGhee Tyson

Tue 3/31

12:02 pm-1:37 pm

Nonstop1h 35m

$118

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Sun 3/29

9:20 pm-10:59 pm

Nonstop1h 39m

Knoxville McGhee Tyson

Sun 4/5

9:46 pm-11:20 pm

Nonstop1h 34m

$119

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Sun 3/29

9:20 pm-10:59 pm

Nonstop1h 39m

Knoxville McGhee Tyson

Thu 4/2

9:46 pm-11:20 pm

Nonstop1h 34m

$120

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Thu 3/26

9:20 pm-10:59 pm

Nonstop1h 39m

Knoxville McGhee Tyson

Sun 3/29

6:55 pm-8:30 pm

Nonstop1h 35m

$121

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Thu 5/28

9:28 pm-11:06 pm

Nonstop1h 38m

Knoxville McGhee Tyson

Tue 6/2

5:00 pm-6:34 pm

Nonstop1h 34m

$122

OrlandoKnoxville

SFB - TYS

SFBTYS

Orlando Sanford Intl

Sat 3/28

7:06 pm-8:45 pm

Nonstop1h 39m

Knoxville McGhee Tyson

Tue 4/7

12:00 pm-1:34 pm

Nonstop1h 34m

$123

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Orlando Sanford Intl Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of August is, on average, the cheapest month to fly to Knoxville from Orlando Sanford Intl Airport, with most prices found around $115. If you aren’t able to travel during the month of August, then book flights to Knoxville from Orlando Sanford Intl Airport during January instead. Flights to Knoxville in January, while not as cheap as those in August, still average around $119.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Orlando Sanford Intl Airport to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $130. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Orlando Sanford Intl Airport to Knoxville for around $177.

What is the cheapest time of day to depart on your flight to Knoxville?

In the evening is the cheapest time of day to fly from Orlando Sanford Intl Airport to Knoxville when you can find flight prices for as low as $133. Flying to Knoxville in the evening is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is at noon when prices are around $160.

What is the cheapest Orlando Sanford Intl to Knoxville McGhee Tyson flight route?

Fly from Orlando Sanford Intl to Knoxville McGhee Tyson for the best Orlando Sanford Intl - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Orlando Sanford Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $154 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Orlando Sanford Intl Airport for as low as $119 on momondo.

What cabin class options are available on Orlando Sanford Intl to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Orlando Sanford Intl to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Orlando Sanford Intl Airport to Knoxville flight prices changed over time?

As of March 2026, prices for Orlando Sanford Intl Airport to Knoxville flights are approximately 13% cheaper when compared to flights at the same time last year.

When to book flights from Orlando Sanford Intl Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando Sanford Intl Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando Sanford Intl Airport to Knoxville (SFB to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando Sanford Intl Airport to Knoxville

Best Price Found

$88

Fastest flight time

1h 35m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Orlando Sanford Intl Airport in the past 72 hours is $88. The best round-trip flight deal from Orlando Sanford Intl Airport to Knoxville found on momondo in the last 72 hours is $137.
The fastest flight from Orlando Sanford Intl Airport to Knoxville takes 1h 35m
Direct flights go from Orlando Sanford Intl Airport to Knoxville every day.
There is 1 airport in Knoxville. From Orlando Sanford Intl Airport there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

  • How far is Orlando Sanford Intl to Knoxville McGhee Tyson by plane?

    There are 520.0 mi between Orlando Sanford Intl and Knoxville McGhee Tyson. A reasonable flight in good conditions will take 1h 35m.

  • When did momondo last update prices for flights from Orlando Sanford Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Orlando Sanford Intl Airport to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Orlando Sanford Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Orlando Sanford Intl Airport to Knoxville McGhee Tyson Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando Sanford Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Orlando Sanford Intl Airport to Knoxville?

  • What is the most popular airline from Orlando Sanford Intl Airport to Knoxville?

Best airlines flying from Orlando Sanford Intl Airport to Knoxville

Compare and see reviews for airlines that fly from Orlando Sanford Intl Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $88Free CancellationRating
7.3
714 reviews
Search Allegiant Air flights

  • Allegiant Air Flights From Orlando Sanford Intl Airport to Knoxville

    Allegiant Air flight deals from Orlando Sanford Intl Airport to Knoxville start from $88 round-trip. Over the 2 Allegiant Air flights for this route in a normal week, average airfare is usually $152 round-trip - but some users have found much cheaper deals with momondo.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Lenoir City
Newport
Kodak
Dandridge
Jefferson City
Clinton
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Orlando.

Can I find flights from Orlando to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Orlando with this policy.

How can momondo help me find flights from Orlando to Knoxville?

momondo provides multiple filters to help you find the best flight to Knoxville from Orlando. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Orlando to Knoxville right now. Can momondo alert me if prices change?

Price alerts on flights to Knoxville from Orlando are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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