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Cheap flights from Orlando Airport to Des Moines from $71

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando Airport to Des Moines departing on 3/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Orlando Airport to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:10 pm - 1:46 pm
MCO
-
DSM
23h 36m
1 stop
Multiple Airlines Logo
8:14 pm - 5:43 am
DSM
-
MCO
8h 29m
1 stop
$206Multiple Airlines
Sat, Apr 4 - Mon, Apr 6
Frontier Logo
6:00 am - 7:14 pm
MCO
-
DSM
14h 14m
1 stop
Frontier Logo
8:14 pm - 5:43 am
DSM
-
MCO
8h 29m
1 stop
$207Frontier
Mon, Apr 6 - Fri, Apr 10
Frontier Logo
6:00 am - 1:09 pm
MCO
-
DSM
8h 09m
1 stop
Frontier Logo
2:04 pm - 5:43 am
DSM
-
MCO
14h 39m
1 stop
$208Frontier
Fri, Apr 24 - Mon, Apr 27
Multiple Airlines Logo
9:17 am - 8:57 pm
MCO
-
DSM
12h 40m
1 stop
Multiple Airlines Logo
8:14 pm - 5:43 am
DSM
-
MCO
8h 29m
1 stop
$233Multiple Airlines
Fri, Apr 3 - Mon, Apr 6
Multiple Airlines Logo
9:17 am - 8:57 pm
MCO
-
DSM
12h 40m
1 stop
Multiple Airlines Logo
8:14 pm - 5:43 am
DSM
-
MCO
8h 29m
1 stop
$248Multiple Airlines
Fri, Apr 3 - Mon, Apr 6
Multiple Airlines Logo
8:59 pm - 10:31 pm
MCO
-
DSM
26h 32m
1 stop
Multiple Airlines Logo
9:51 pm - 12:20 pm
DSM
-
MCO
13h 29m
1 stop
$263Multiple Airlines
Wed, May 27 - Mon, Jun 1
Multiple Airlines Logo
9:17 am - 8:57 pm
MCO
-
DSM
12h 40m
1 stop
Multiple Airlines Logo
3:21 pm - 11:50 pm
DSM
-
MCO
7h 29m
1 stop
$269Multiple Airlines
Fri, Apr 3 - Sun, Apr 5
Frontier Logo
8:38 pm - 7:14 pm
MCO
-
DSM
23h 36m
1 stop
Frontier Logo
8:14 pm - 5:43 am
DSM
-
MCO
8h 29m
1 stop
$271Frontier
Thu, Apr 2 - Mon, Apr 6
Multiple Airlines Logo
2:29 pm - 9:27 pm
MCO
-
DSM
7h 58m
1 stop
Multiple Airlines Logo
12:56 pm - 12:20 pm
DSM
-
MCO
22h 24m
1 stop
$273Multiple Airlines
Thu, Jun 11 - Mon, Jun 15
Multiple Airlines Logo
10:25 am - 10:06 pm
MCO
-
DSM
12h 41m
1 stop
Multiple Airlines Logo
2:36 pm - 11:50 pm
DSM
-
MCO
8h 14m
1 stop
$275Multiple Airlines
Thu, Apr 9 - Sun, Apr 12

Frontier flights from Orlando Airport to Des Moines

Our best Frontier deals on Orlando Airport to Des Moines flight tickets
Frontier
Apr 6
MCO6:00 amOrlando
14h 14m
1 stop
DSM7:14 pmDes Moines
Apr 10
DSM8:14 pmDes Moines
8h 29m
1 stop
MCO5:43 amOrlando
$207
Frontier
Apr 24
MCO6:00 amOrlando
8h 09m
1 stop
DSM1:09 pmDes Moines
Apr 27
DSM2:04 pmDes Moines
14h 39m
1 stop
MCO5:43 amOrlando
$208
Frontier
Mar 27
MCO12:08 pmOrlando
8h 08m
1 stop
DSM7:16 pmDes Moines
Mar 28
DSM6:56 pmDes Moines
2h 57m
MCO10:53 pmOrlando
$215

Southwest flights from Orlando Airport to Des Moines

Our best Southwest deals on Orlando Airport to Des Moines flight tickets
Southwest
Apr 18
MCO7:20 amOrlando
5h 10m
1 stop
DSM11:30 amDes Moines
Apr 25
DSM2:10 pmDes Moines
8h 00m
1 stop
MCO11:10 pmOrlando
$345
Southwest
Apr 18
MCO8:25 amOrlando
13h 30m
2 stops
DSM8:55 pmDes Moines
Apr 25
DSM2:10 pmDes Moines
8h 00m
1 stop
MCO11:10 pmOrlando
$346
Southwest
Apr 2
MCO1:35 pmOrlando
9h 45m
2 stops
DSM10:20 pmDes Moines
Apr 6
DSM5:35 amDes Moines
7h 15m
2 stops
MCO1:50 pmOrlando
$523

momondo Fare Finder

 
Customize your flight search to find flights from Orlando Airport to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Orlando Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Sat 4/4

3:10 pm-1:46 pm

1 stop23h 36m

Des Moines

Mon 4/6

8:14 pm-5:43 am

1 stop8h 29m

$206

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Mon 4/6

6:00 am-7:14 pm

1 stop14h 14m

Des Moines

Fri 4/10

8:14 pm-5:43 am

1 stop8h 29m

$207

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 4/24

6:00 am-1:09 pm

1 stop8h 09m

Des Moines

Mon 4/27

2:04 pm-5:43 am

1 stop14h 39m

$208

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 4/3

9:17 am-8:57 pm

1 stop12h 40m

Des Moines

Mon 4/6

8:14 pm-5:43 am

1 stop8h 29m

$233

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 4/3

9:17 am-8:57 pm

1 stop12h 40m

Des Moines

Mon 4/6

8:14 pm-5:43 am

1 stop8h 29m

$248

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Wed 5/27

8:59 pm-10:31 pm

1 stop26h 32m

Des Moines

Mon 6/1

9:51 pm-12:20 pm

1 stop13h 29m

$263
Quickest round-trip

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 4/3

9:17 am-8:57 pm

1 stop12h 40m

Des Moines

Sun 4/5

3:21 pm-11:50 pm

1 stop7h 29m

$269

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 4/2

8:38 pm-7:14 pm

1 stop23h 36m

Des Moines

Mon 4/6

8:14 pm-5:43 am

1 stop8h 29m

$271

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 6/11

2:29 pm-9:27 pm

1 stop7h 58m

Des Moines

Mon 6/15

12:56 pm-12:20 pm

1 stop22h 24m

$273

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 4/9

10:25 am-10:06 pm

1 stop12h 41m

Des Moines

Sun 4/12

2:36 pm-11:50 pm

1 stop8h 14m

$275

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Orlando Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Orlando Airport to Des Moines is on a Tuesday. Travelers who choose to depart for Des Moines on a Tuesday will often find tickets for as low as $129. Flights from Orlando Airport to Des Moines on a Monday will generally be more expensive and average around $338. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Orlando Airport to Des Moines in the evening for as low as $158. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $220. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Orlando to Des Moines flight route?

Fly from Orlando to Des Moines for the best Orlando - Des Moines flight prices

What cabin class options are available on Orlando to Des Moines flights?

There is only 1 cabin class available to choose from on Orlando to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Orlando Airport to Des Moines flights?

You could potentially save up to 37% on your flight if you consider stops on a Orlando Airport to Des Moines flight.

How have Orlando Airport to Des Moines flight prices changed over time?

As of March 2026, prices for Orlando Airport to Des Moines flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from Orlando Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando Airport to Des Moines (MCO to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando Airport to Des Moines

Best Price Found

$174

Fastest flight time

5h 53m

Direct flights

Sun

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Orlando Airport in the past 72 hours is $174. The best round-trip flight deal from Orlando Airport to Des Moines found on momondo in the last 72 hours is $90.
The fastest flight from Orlando Airport to Des Moines takes 5h 53m
Direct flights go from Orlando Airport to Des Moines on Sunday. The only airline offering direct flights is Frontier.
There is 1 airport in Des Moines. From Orlando Airport there are direct flights to Des Moines (DSM).
Search flight deals

  • How far is Orlando to Des Moines by plane?

    A flight from Orlando to Des Moines will travel around 1142.1 mi. Typically, this will take 5h 53m by plane in normal conditions.

  • When did momondo last update prices for flights from Orlando Airport to Des Moines Airport?

    Prices for flights from Orlando Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Orlando Airport to Des Moines Airport?

  • How old do you have to be to fly from Orlando Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando Airport to Des Moines?

  • What is the most popular airline from Orlando Airport to Des Moines?

Best airlines flying from Orlando Airport to Des Moines

Compare and see reviews for airlines that fly from Orlando Airport to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $90Free CancellationRating
5.7
3,020 reviews
Search Frontier flights
DeltaPriceFrom $236Free CancellationRating
7.9
8,318 reviews
Search Delta flights
American AirlinesPriceFrom $285Free CancellationRating
7.1
11,487 reviews
Search American Airlines flights

  • Frontier Flights From Orlando Airport to Des Moines

    Across 2 Frontier flights from Orlando Airport to Des Moines this week, the average price was $130, with the best Frontier deals starting from $90 round-trip. 3,020 users have rated Frontier on momondo, with an average score of 5.7/10.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Orlando to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Orlando to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Orlando on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Orlando to Des Moines?

Once you have performed a search for Orlando to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Orlando to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Orlando are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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