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Cheap flights from Orlando Airport to Des Moines from $80

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Orlando Airport to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:55 am - 2:42 pmMCO  Orlando-DSM Des Moines
8h 47m1 stop Philadelphia
Multiple Airlines Logo
8:00 am - 7:28 pmDSM  Des Moines-MCO Orlando
34h 28m2 stops Philadelphia Atlanta Hartsfield-Jackson
$249Multiple Airlines
Thu, Oct 22 - Sun, Oct 25
Frontier Logo
5:46 pm - 7:30 pmMCO  Orlando-DSM Des Moines
26h 44m1 stop Denver Intl
Frontier Logo
8:25 pm - 12:37 amDSM  Des Moines-MCO Orlando
27h 12m1 stop Denver Intl
$250Frontier
Thu, Oct 22 - Mon, Oct 26
Multiple Airlines Logo
6:55 am - 2:42 pmMCO  Orlando-DSM Des Moines
8h 47m1 stop Philadelphia
Multiple Airlines Logo
8:00 am - 1:24 pmDSM  Des Moines-MCO Orlando
28h 24m1 stop Philadelphia
$261Multiple Airlines
Thu, Oct 22 - Sun, Oct 25
Frontier Logo
5:55 am - 7:30 pmMCO  Orlando-DSM Des Moines
14h 35m1 stop Denver Intl
Frontier Logo
8:25 pm - 12:37 amDSM  Des Moines-MCO Orlando
27h 12m1 stop Denver Intl
$335Frontier
Fri, Oct 23 - Mon, Oct 26
Delta Logo
5:30 am - 10:42 amMCO  Orlando-DSM Des Moines
6h 12m1 stop Atlanta Hartsfield-Jackson
Delta Logo
11:00 am - 7:45 pmDSM  Des Moines-MCO Orlando
7h 45m1 stop Minneapolis St Paul
$339Delta
Sat, Nov 7 - Sat, Nov 14
Delta Logo
6:34 am - 2:25 pmMCO  Orlando-DSM Des Moines
8h 51m1 stop Minneapolis St Paul
Delta Logo
11:27 am - 5:33 pmDSM  Des Moines-MCO Orlando
5h 06m1 stop Atlanta Hartsfield-Jackson
$339Delta
Sat, Oct 24 - Sat, Oct 31
American Airlines Logo
6:05 am - 10:42 amMCO  Orlando-DSM Des Moines
5h 37m1 stop Charlotte Douglas
American Airlines Logo
2:01 pm - 10:55 pmDSM  Des Moines-MCO Orlando
7h 54m1 stop Chicago O'Hare Intl
$339American Airlines
Thu, Oct 22 - Mon, Oct 26
American Airlines Logo
4:48 pm - 11:26 pmMCO  Orlando-DSM Des Moines
7h 38m1 stop Charlotte Douglas
American Airlines Logo
3:31 pm - 10:54 pmDSM  Des Moines-MCO Orlando
6h 23m1 stop Dallas/Fort Worth
$339American Airlines
Wed, Nov 4 - Wed, Nov 11
United Airlines Logo
11:50 am - 7:16 pmMCO  Orlando-DSM Des Moines
8h 26m2 stops Washington, D.C. Dulles Intl Chicago O'Hare Intl
United Airlines Logo
3:24 pm - 9:37 pmDSM  Des Moines-MCO Orlando
5h 13m1 stop Chicago O'Hare Intl
$393United Airlines
Sat, Nov 21 - Mon, Nov 23
United Airlines Logo
7:15 am - 12:34 pmMCO  Orlando-DSM Des Moines
6h 19m1 stop Chicago O'Hare Intl
United Airlines Logo
3:11 pm - 11:56 pmDSM  Des Moines-MCO Orlando
7h 45m1 stop Chicago O'Hare Intl
$449United Airlines
Thu, Oct 15 - Mon, Oct 19

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American Airlines flights from Orlando Airport to Des Moines

Our best American Airlines deals on Orlando Airport to Des Moines flight tickets
American Airlines
Nov 21
MCO5:33 pmOrlando
7h 46m
1 stop
DSM12:19 amDes Moines
Nov 23
DSM7:11 amDes Moines
6h 37m
1 stop
MCO2:48 pmOrlando
$359
American Airlines
Nov 17
MCO5:21 pmOrlando
7h 57m
1 stop
DSM12:18 amDes Moines
Nov 19
DSM6:00 amDes Moines
6h 32m
1 stop
MCO1:32 pmOrlando
$383
American Airlines
Oct 21
MCO6:12 amOrlando
8h 18m
1 stop
DSM1:30 pmDes Moines
Oct 25
DSM7:29 amDes Moines
7h 32m
1 stop
MCO4:01 pmOrlando
$388

United Airlines flights from Orlando Airport to Des Moines

Our best United Airlines deals on Orlando Airport to Des Moines flight tickets
United Airlines
Oct 15
MCO7:15 amOrlando
6h 19m
1 stop
DSM12:34 pmDes Moines
Oct 19
DSM3:11 pmDes Moines
7h 45m
1 stop
MCO11:56 pmOrlando
$449
United Airlines
Oct 15
MCO9:00 amOrlando
9h 48m
2 stops
DSM5:48 pmDes Moines
Oct 19
DSM3:11 pmDes Moines
7h 45m
1 stop
MCO11:56 pmOrlando
$454
United Airlines
Oct 8
MCO10:01 amOrlando
7h 19m
1 stop
DSM4:20 pmDes Moines
Oct 12
DSM3:11 pmDes Moines
5h 56m
1 stop
MCO10:07 pmOrlando
$653

momondo Fare Finder

 
Use the filters below to find and compare flights from Orlando Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 10/22

6:55 am-2:42 pm

1 stop8h 47m

Des Moines

Sun 10/25

8:00 am-7:28 pm

2 stops34h 28m

$249

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 10/22

5:46 pm-7:30 pm

1 stop26h 44m

Des Moines

Mon 10/26

8:25 pm-12:37 am

1 stop27h 12m

$250

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 10/22

6:55 am-2:42 pm

1 stop8h 47m

Des Moines

Sun 10/25

8:00 am-1:24 pm

1 stop28h 24m

$261

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Fri 10/23

5:55 am-7:30 pm

1 stop14h 35m

Des Moines

Mon 10/26

8:25 pm-12:37 am

1 stop27h 12m

$335

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Sat 11/7

5:30 am-10:42 am

1 stop6h 12m

Des Moines

Sat 11/14

11:00 am-7:45 pm

1 stop7h 45m

$339

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Sat 10/24

6:34 am-2:25 pm

1 stop8h 51m

Des Moines

Sat 10/31

11:27 am-5:33 pm

1 stop5h 06m

$339
Quickest round-trip

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 10/22

6:05 am-10:42 am

1 stop5h 37m

Des Moines

Mon 10/26

2:01 pm-10:55 pm

1 stop7h 54m

$339

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Wed 11/4

4:48 pm-11:26 pm

1 stop7h 38m

Des Moines

Wed 11/11

3:31 pm-10:54 pm

1 stop6h 23m

$339

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Sat 11/21

11:50 am-7:16 pm

2 stops8h 26m

Des Moines

Mon 11/23

3:24 pm-9:37 pm

1 stop5h 13m

$393

OrlandoDes Moines

MCO Orlando - DSM Des Moines

MCODSM

Orlando

Thu 10/15

7:15 am-12:34 pm

1 stop6h 19m

Des Moines

Mon 10/19

3:11 pm-11:56 pm

1 stop7h 45m

$449

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Orlando Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Orlando Airport and Des Moines?

Prices are currently typical for flights on this route.

Typical prices usually range from $236 to $487.
The lowest price recently found on this route was $249.

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in April, then March is your next best option. Flight prices from Orlando Airport to Des Moines during March average around $129.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Orlando Airport to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $157. Flights from Orlando Airport to Des Moines on a Monday will generally be more expensive and average around $394. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Orlando Airport to Des Moines in the evening for as low as $158. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $360. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Orlando to Des Moines flight route?

Fly from Orlando to Des Moines for the best Orlando - Des Moines flight prices

What cabin class options are available on Orlando Airport to Des Moines flights?

There is only 1 cabin class available to choose from on Orlando Airport to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Orlando Airport to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Orlando Airport to Des Moines.

How have Orlando Airport to Des Moines flight prices changed over time?

As of September 2026, prices for Orlando Airport to Des Moines flights are approximately 14% more expensive when compared to flights at the same time last year.

When to book flights from Orlando Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando Airport to Des Moines (MCO to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando Airport to Des Moines

Best Price Found

$80

Fastest flight time

5h 04m

Direct flights

Mon and Wed

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Orlando Airport in the past 72 hours is $80. The best round-trip flight deal from Orlando Airport to Des Moines found on momondo in the last 72 hours is $249.
The fastest flight from Orlando Airport to Des Moines takes 5h 04m
Direct flights go from Orlando Airport to Des Moines on Monday and Wednesday. The only airline offering direct flights is Frontier.
There is 1 airport in Des Moines. From Orlando Airport there are direct flights to Des Moines (DSM).
Search flight deals

Frequently asked questions about flying from Orlando Airport to Des Moines

  • How far is Orlando to Des Moines by plane?

    A flight from Orlando to Des Moines will travel around 1142.1 mi. Typically, this will take 5h 04m by plane in normal conditions.

  • When did momondo last update prices for flights from Orlando Airport to Des Moines Airport?

    Prices for flights from Orlando Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Orlando Airport to Des Moines Airport?

  • How old do you have to be to fly from Orlando Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando Airport to Des Moines?

  • What is the most popular airline from Orlando Airport to Des Moines?

Best airlines flying from Orlando Airport to Des Moines

Compare and see reviews for airlines that fly from Orlando Airport to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $90Free CancellationRating
5.6
2,572 reviews
Search Frontier flights
DeltaPriceFrom $316Free CancellationRating
7.8
8,607 reviews
Search Delta flights
American AirlinesPriceFrom $337Free CancellationRating
7.0
12,098 reviews
Search American Airlines flights
United AirlinesPriceFrom $374Free CancellationRating
7.4
10,242 reviews
Search United Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Newton
Boone
Johnston
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Orlando to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Orlando to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Orlando on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Orlando to Des Moines?

Once you have performed a search for Orlando to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Orlando to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Orlando are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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