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Cheap flights from Orlando Airport to Des Moines from $105

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Orlando Airport to Des Moines departing on 8/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Orlando Airport to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
6:00 am - 1:34 pm
MCO
-
DSM
8h 34m
1 stop
Frontier Logo
2:19 pm - 11:47 am
DSM
-
MCO
20h 28m
1 stop
$242Frontier
Wed, Aug 5 - Fri, Aug 7
Frontier Logo
8:33 pm - 1:31 pm
MCO
-
DSM
17h 58m
1 stop
Frontier Logo
2:16 pm - 5:38 am
DSM
-
MCO
14h 22m
1 stop
$243Frontier
Thu, Aug 20 - Wed, Aug 26
Multiple Airlines Logo
6:14 am - 9:31 pm
MCO
-
DSM
16h 17m
1 stop
Multiple Airlines Logo
5:12 pm - 6:40 am
DSM
-
MCO
36h 28m
2 stops
$250Multiple Airlines
Sun, Aug 9 - Sun, Aug 16
Multiple Airlines Logo
10:00 am - 11:07 pm
MCO
-
DSM
14h 07m
2 stops
Multiple Airlines Logo
5:30 pm - 2:25 pm
DSM
-
MCO
19h 55m
1 stop
$259Multiple Airlines
Thu, Jul 16 - Mon, Jul 20
Multiple Airlines Logo
10:00 am - 11:07 pm
MCO
-
DSM
14h 07m
2 stops
Multiple Airlines Logo
5:30 pm - 2:25 pm
DSM
-
MCO
19h 55m
1 stop
$270Multiple Airlines
Thu, Jul 9 - Mon, Jul 13
Multiple Airlines Logo
7:45 am - 11:19 pm
MCO
-
DSM
16h 34m
2 stops
Multiple Airlines Logo
3:41 pm - 11:56 pm
DSM
-
MCO
7h 15m
1 stop
$274Multiple Airlines
Thu, Aug 6 - Sun, Aug 9
Multiple Airlines Logo
6:14 am - 9:31 pm
MCO
-
DSM
16h 17m
1 stop
Multiple Airlines Logo
7:30 am - 1:40 pm
DSM
-
MCO
29h 10m
1 stop
$275Multiple Airlines
Sun, Aug 9 - Thu, Aug 13
Frontier Logo
5:35 am - 1:34 pm
MCO
-
DSM
8h 59m
1 stop
Frontier Logo
2:19 pm - 5:38 am
DSM
-
MCO
14h 19m
1 stop
$277Frontier
Fri, Sep 4 - Mon, Sep 7
Frontier Logo
7:17 am - 1:56 pm
MCO
-
DSM
7h 39m
1 stop
Frontier Logo
2:51 pm - 4:09 pm
DSM
-
MCO
24h 18m
1 stop
$279Frontier
Fri, Sep 11 - Mon, Sep 14
Frontier Logo
8:43 pm - 1:34 pm
MCO
-
DSM
17h 51m
1 stop
Frontier Logo
2:19 pm - 9:02 pm
DSM
-
MCO
29h 43m
1 stop
$280Frontier
Thu, Jul 16 - Mon, Jul 20

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Southwest flights from Orlando Airport to Des Moines

Our best Southwest deals on Orlando Airport to Des Moines flight tickets
Southwest
Jul 15
MCO4:40 pmOrlando
7h 10m
2 stops
DSM10:50 pmDes Moines
Jul 22
DSM3:45 pmDes Moines
7h 05m
1 stop
MCO11:50 pmOrlando
$338
Southwest
Sep 6
MCO7:25 amOrlando
5h 55m
1 stop
DSM12:20 pmDes Moines
Sep 8
DSM6:10 amDes Moines
7h 50m
2 stops
MCO3:00 pmOrlando
$357
Southwest
Aug 6
MCO2:05 pmOrlando
9h 05m
2 stops
DSM10:10 pmDes Moines
Aug 12
DSM2:40 pmDes Moines
6h 20m
1 stop
MCO10:00 pmOrlando
$359

Frontier flights from Orlando Airport to Des Moines

Our best Frontier deals on Orlando Airport to Des Moines flight tickets
Frontier
Aug 5
MCO6:00 amOrlando
8h 34m
1 stop
DSM1:34 pmDes Moines
Aug 7
DSM2:19 pmDes Moines
20h 28m
1 stop
MCO11:47 amOrlando
$242
Frontier
Aug 20
MCO8:33 pmOrlando
17h 58m
1 stop
DSM1:31 pmDes Moines
Aug 26
DSM2:16 pmDes Moines
14h 22m
1 stop
MCO5:38 amOrlando
$243
Frontier
Aug 12
MCO6:00 amOrlando
8h 34m
1 stop
DSM1:34 pmDes Moines
Aug 14
DSM2:19 pmDes Moines
25h 11m
1 stop
MCO4:30 pmOrlando
$270

momondo Fare Finder

 
Customize your flight search to find flights from Orlando Airport to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 20, 2026.
Use the filters below to find and compare flights from Orlando Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Wed 8/5

6:00 am-1:34 pm

1 stop8h 34m

Des Moines

Fri 8/7

2:19 pm-11:47 am

1 stop20h 28m

$242

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 8/20

8:33 pm-1:31 pm

1 stop17h 58m

Des Moines

Wed 8/26

2:16 pm-5:38 am

1 stop14h 22m

$243

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Sun 8/9

6:14 am-9:31 pm

1 stop16h 17m

Des Moines

Sun 8/16

5:12 pm-6:40 am

2 stops36h 28m

$250

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 7/16

10:00 am-11:07 pm

2 stops14h 07m

Des Moines

Mon 7/20

5:30 pm-2:25 pm

1 stop19h 55m

$259

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 7/9

10:00 am-11:07 pm

2 stops14h 07m

Des Moines

Mon 7/13

5:30 pm-2:25 pm

1 stop19h 55m

$270

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 8/6

7:45 am-11:19 pm

2 stops16h 34m

Des Moines

Sun 8/9

3:41 pm-11:56 pm

1 stop7h 15m

$274

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Sun 8/9

6:14 am-9:31 pm

1 stop16h 17m

Des Moines

Thu 8/13

7:30 am-1:40 pm

1 stop29h 10m

$275
Quickest round-trip

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 9/4

5:35 am-1:34 pm

1 stop8h 59m

Des Moines

Mon 9/7

2:19 pm-5:38 am

1 stop14h 19m

$277

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Fri 9/11

7:17 am-1:56 pm

1 stop7h 39m

Des Moines

Mon 9/14

2:51 pm-4:09 pm

1 stop24h 18m

$279

OrlandoDes Moines

MCO - DSM

MCODSM

Orlando

Thu 7/16

8:43 pm-1:34 pm

1 stop17h 51m

Des Moines

Mon 7/20

2:19 pm-9:02 pm

1 stop29h 43m

$280

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Orlando Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Orlando Airport and Des Moines?

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in April, then March is your next best option. Flight prices from Orlando Airport to Des Moines during March average around $129.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Orlando Airport to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $157. Flights from Orlando Airport to Des Moines on a Monday will generally be more expensive and average around $394. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the afternoon. momondo users have found flights departing from Orlando Airport to Des Moines in the afternoon for as low as $153. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets at noon because they tend to be around $320. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Orlando to Des Moines flight route?

Fly from Orlando to Des Moines for the best Orlando - Des Moines flight prices

What cabin class options are available on Orlando Airport to Des Moines flights?

There is only 1 cabin class available to choose from on Orlando Airport to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Orlando Airport to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Orlando Airport to Des Moines.

How have Orlando Airport to Des Moines flight prices changed over time?

As of June 2026, prices for Orlando Airport to Des Moines flights are approximately 125% more expensive when compared to flights at the same time last year.

When to book flights from Orlando Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Orlando Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Orlando Airport to Des Moines (MCO to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Orlando Airport to Des Moines

Fastest flight time

5h 28m

Direct flights

None
The fastest flight from Orlando Airport to Des Moines takes 5h 28m
There are no direct flights from Orlando Airport to Des Moines. There are no popular flight routes from Orlando Airport to Des Moines.
Search flight deals

Frequently asked questions about flying from Orlando Airport to Des Moines

  • How far is Orlando to Des Moines by plane?

    A flight from Orlando to Des Moines will travel around 1142.1 mi. Typically, this will take 5h 28m by plane in normal conditions.

  • When did momondo last update prices for flights from Orlando Airport to Des Moines Airport?

    Prices for flights from Orlando Airport to Des Moines Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Orlando Airport to Des Moines Airport?

  • How old do you have to be to fly from Orlando Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Orlando Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The necessary travel and health documents for your Des Moines Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Orlando Airport to Des Moines?

  • What is the most popular airline from Orlando Airport to Des Moines?

Best airlines flying from Orlando Airport to Des Moines

Compare and see reviews for airlines that fly from Orlando Airport to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
FrontierPriceFrom $90Free CancellationRating
5.6
2,878 reviews
Search Frontier flights
DeltaPriceFrom $266Free CancellationRating
7.8
8,419 reviews
Search Delta flights
American AirlinesPriceFrom $287Free CancellationRating
7.1
11,710 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Osceola
Urbandale
Newton
Johnston
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Orlando to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Orlando to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Orlando to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Orlando on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Orlando to Des Moines?

Once you have performed a search for Orlando to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Orlando to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Orlando are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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