What is the cheapest airline that flies from Ohio to Greenville?

Breeze Airways, Delta, and United Airlines are the most popular carriers operating from Ohio to Greenville

How many flights depart from Ohio to Greenville on average per week?

The number of flights available between Ohio and Greenville is 2 per week as of November 2026. The most frequent departure day is Mon, with 50% of weekly flights leaving on this day.

How long does it take to fly to Greenville?

Flight times from Ohio to Greenville vary, but if you’re flying out of Cincinnati and flying into Charlotte (one of the most popular routes), then the duration is 1h 32m on average. Another popular route from Ohio to Greenville is flying from Columbus to Charlotte, which will take roughly 1h 38m. Keep in mind that layovers or delays could extend your travel time.

What airlines fly to Greenville?

American Airlines, Delta and Frontier are the top three most popular airlines that fly to Greenville from Ohio according to our data. American Airlines is the first choice among our users, with 75% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 6 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Ohio to Greenville Airport?

Prices for flights from Ohio to Greenville Airport are refreshed on a daily basis.

How many operators does momondo search for flights from Ohio to Greenville Airport?

There are 5 operators available for flights from Ohio to Greenville Airport as of November 2026.

How old do you have to be to fly from Ohio to Greenville Airport?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$69 Cheap Flights from Ohio to Greenville in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Ohio to Greenville

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:09 am - 11:26 amCVG Cincinnati Cinci./N. Kentucky-GSP Greenville

1h 17mnonstop

5:16 pm - 6:39 pmGSP Greenville-CVG Cincinnati Cinci./N. Kentucky

1h 23mnonstop

$123Breeze Airways

Mon, May 10 - Fri, May 14

6:32 pm - 7:52 pmCMH Columbus-GSP Greenville

1h 20mnonstop

4:27 pm - 5:52 pmGSP Greenville-CMH Columbus

1h 25mnonstop

$152Breeze Airways

Fri, Nov 20 - Mon, Nov 23

6:32 pm - 7:52 pmCMH Columbus-GSP Greenville

1h 20mnonstop

8:52 pm - 11:58 amGSP Greenville-CMH Columbus

15h 06m3 stops Tampa Fort Lauderdale Atlanta Hartsfield-Jackson

$167Multiple Airlines

Fri, Dec 11 - Mon, Dec 14

6:32 pm - 7:52 pmCMH Columbus-GSP Greenville

1h 20mnonstop

2:42 pm - 4:40 pmGSP Greenville-CMH Columbus

25h 58m1 stop Fort Lauderdale

$168Multiple Airlines

Fri, Nov 20 - Mon, Nov 23

5:28 am - 11:12 amCVG Cincinnati Cinci./N. Kentucky-GSP Greenville

5h 44m1 stop Chicago O'Hare Intl

7:23 pm - 11:20 pmGSP Greenville-CVG Cincinnati Cinci./N. Kentucky

3h 57m1 stop Charlotte Douglas

$237American Airlines

Fri, Jan 8 - Mon, Jan 11

6:45 pm - 11:47 pmCVG Cincinnati Cinci./N. Kentucky-GSP Greenville

5h 02m1 stop Atlanta Hartsfield-Jackson

5:40 am - 11:25 amGSP Greenville-CVG Cincinnati Cinci./N. Kentucky

5h 45m1 stop Atlanta Hartsfield-Jackson

$237Delta

Fri, Dec 11 - Mon, Dec 14

7:05 am - 11:07 amCMH Columbus-GSP Greenville

4h 02m1 stop Atlanta Hartsfield-Jackson

7:00 am - 12:01 pmGSP Greenville-CMH Columbus

5h 01m1 stop Atlanta Hartsfield-Jackson

$237Delta

Mon, Nov 23 - Mon, Nov 30

8:30 am - 6:15 pmCVG Cincinnati Cinci./N. Kentucky-GSP Greenville

9h 45m2 stops Chicago Midway Nashville Intl

8:25 am - 12:35 pmGSP Greenville-CVG Cincinnati Cinci./N. Kentucky

4h 10m1 stop Baltimore/Washington

$242Southwest

Fri, Jan 8 - Mon, Jan 11

6:08 am - 11:37 amCVG Cincinnati Cinci./N. Kentucky-GSP Greenville

5h 29m1 stop Charlotte Douglas

2:57 pm - 7:56 pmGSP Greenville-CVG Cincinnati Cinci./N. Kentucky

4h 59m1 stop Washington, D.C. Reagan-National

$270American Airlines

Sat, Jan 9 - Mon, Jan 11

8:15 am - 6:15 pmCLE Cleveland Hopkins Intl-GSP Greenville

10h 00m2 stops Chicago Midway Nashville Intl

7:30 am - 5:10 pmGSP Greenville-CLE Cleveland Hopkins Intl

9h 40m2 stops Baltimore/Washington Nashville Intl

$343Southwest

Wed, Feb 3 - Mon, Feb 8

Cheap last minute flights

Enter your travel dates to find the best prices.

9:18 pm - 8:13 amCLE Cleveland Hopkins Intl-GSP Greenville

10h 55m1 stop Fort Lauderdale

8:52 pm - 8:03 pmGSP Greenville-CLE Cleveland Hopkins Intl

23h 11m2 stops Tampa Fort Lauderdale

$191Multiple Airlines

Sun, Nov 15 - Mon, Nov 16

9:18 pm - 8:13 amCLE Cleveland Hopkins Intl-GSP Greenville

10h 55m1 stop Fort Lauderdale

2:42 pm - 8:03 pmGSP Greenville-CLE Cleveland Hopkins Intl

29h 21m1 stop Fort Lauderdale

$195Multiple Airlines

Sun, Nov 15 - Mon, Nov 16

12:07 pm - 8:13 amCAK Akron/Canton-GSP Greenville

20h 06m2 stops Jacksonville Fort Lauderdale

8:52 pm - 5:39 pmGSP Greenville-CAK Akron/Canton

20h 47m1 stop Tampa

$355Breeze Airways

Sun, Nov 15 - Mon, Nov 16

5:07 pm - 9:59 pmCAK Akron/Canton-GSP Greenville

4h 52m1 stop Chicago O'Hare Intl

3:28 pm - 9:26 pmGSP Greenville-CAK Akron/Canton

5h 58m1 stop Washington, D.C. Reagan-National

$379American Airlines

Fri, Nov 13 - Mon, Nov 23

5:10 am - 10:51 amCAK Akron/Canton-GSP Greenville

5h 41m1 stop Washington, D.C. Reagan-National

11:39 am - 4:17 pmGSP Greenville-CAK Akron/Canton

4h 38m1 stop Chicago O'Hare Intl

$409American Airlines

Wed, Nov 11 - Wed, Nov 18

10:17 am - 4:56 pmCAK Akron/Canton-GSP Greenville

6h 39m1 stop Chicago O'Hare Intl

6:20 am - 1:12 pmGSP Greenville-CAK Akron/Canton

6h 52m1 stop Chicago O'Hare Intl

$409United Airlines

Wed, Nov 11 - Wed, Nov 18

2:50 pm - 11:47 pmDAY Dayton-GSP Greenville

8h 57m2 stops Washington, D.C. Dulles Intl Newark

6:20 am - 10:58 amGSP Greenville-DAY Dayton

4h 38m1 stop Chicago O'Hare Intl

$524United Airlines

Fri, Nov 13 - Sun, Nov 15

8:55 pm - 7:44 pmDAY Dayton-GSP Greenville

22h 49m2 stops Fort Lauderdale Tampa

8:04 pm - 8:33 amGSP Greenville-DAY Dayton

12h 29m1 stop Fort Myers SW Florida Intl

$529Breeze Airways

Fri, Nov 13 - Sun, Nov 15

6:00 am - 9:47 amCLE Cleveland Hopkins Intl-GSP Greenville

3h 47m1 stop Atlanta Hartsfield-Jackson

6:50 pm - 11:53 pmGSP Greenville-CLE Cleveland Hopkins Intl

5h 03m1 stop Detroit Metropolitan Wayne County

$601Delta

Wed, Nov 11 - Wed, Nov 11

5:30 am - 2:10 pmCLE Cleveland Hopkins Intl-GSP Greenville

8h 40m2 stops Baltimore/Washington Nashville Intl

6:40 am - 6:05 pmGSP Greenville-CLE Cleveland Hopkins Intl

11h 25m2 stops Nashville Intl Orlando

$650Southwest

Mon, Nov 16 - Fri, Nov 20

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United Airlines flights from Ohio to Greenville

Our best United Airlines deals on Ohio to Greenville flight tickets

United Airlines

Dec 1

CVG2:10 pmCincinnati Cinci./N. Kentucky

6h 49m

1 stop

GSP8:59 pmGreenville

Dec 2

GSP5:34 pmGreenville

6h 18m

1 stop

CVG11:52 pmCincinnati Cinci./N. Kentucky

$303

United Airlines

Dec 4

CVG5:15 amCincinnati Cinci./N. Kentucky

4h 37m

1 stop

GSP9:52 amGreenville

Dec 6

GSP6:30 amGreenville

6h 58m

1 stop

CVG1:28 pmCincinnati Cinci./N. Kentucky

$313

United Airlines

Dec 7

CVG12:16 pmCincinnati Cinci./N. Kentucky

4h 37m

1 stop

GSP4:53 pmGreenville

Dec 11

GSP7:48 pmGreenville

4h 11m

1 stop

CVG11:59 pmCincinnati Cinci./N. Kentucky

$369

American Airlines flights from Ohio to Greenville

Our best American Airlines deals on Ohio to Greenville flight tickets

American Airlines

Jan 9

CVG6:08 amCincinnati Cinci./N. Kentucky

5h 29m

1 stop

GSP11:37 amGreenville

Jan 11

GSP2:57 pmGreenville

4h 59m

1 stop

CVG7:56 pmCincinnati Cinci./N. Kentucky

$270

American Airlines

Jan 20

CVG1:04 pmCincinnati Cinci./N. Kentucky

5h 39m

1 stop

GSP6:43 pmGreenville

Jan 26

GSP10:27 amGreenville

6h 21m

1 stop

CVG4:48 pmCincinnati Cinci./N. Kentucky

$279

American Airlines

Dec 13

CVG5:32 amCincinnati Cinci./N. Kentucky

5h 34m

1 stop

GSP11:06 amGreenville

Jan 8

GSP6:57 amGreenville

5h 34m

1 stop

CVG12:31 pmCincinnati Cinci./N. Kentucky

$297

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Quickest round-trip

CincinnatiGreenville

CVG Cincinnati Cinci./N. Kentucky - GSP Greenville

CVGGSP

Cincinnati Cinci./N. Kentucky

Mon 5/10

10:09 am-11:26 am

Nonstop1h 17m

Greenville

Fri 5/14

5:16 pm-6:39 pm

Nonstop1h 23m

$123

ColumbusGreenville

CMH Columbus - GSP Greenville

CMHGSP

Columbus

Fri 11/20

6:32 pm-7:52 pm

Nonstop1h 20m

Greenville

Mon 11/23

4:27 pm-5:52 pm

Nonstop1h 25m

$152

ColumbusGreenville

CMH Columbus - GSP Greenville

CMHGSP

Columbus

Fri 12/11

6:32 pm-7:52 pm

Nonstop1h 20m

Greenville

Mon 12/14

8:52 pm-11:58 am

3 stops15h 06m

$167

ColumbusGreenville

CMH Columbus - GSP Greenville

CMHGSP

Columbus

Fri 11/20

6:32 pm-7:52 pm

Nonstop1h 20m

Greenville

Mon 11/23

2:42 pm-4:40 pm

1 stop25h 58m

$168

CincinnatiGreenville

CVG Cincinnati Cinci./N. Kentucky - GSP Greenville

CVGGSP

Cincinnati Cinci./N. Kentucky

Fri 1/8

5:28 am-11:12 am

1 stop5h 44m

Greenville

Mon 1/11

7:23 pm-11:20 pm

1 stop3h 57m

$237

CincinnatiGreenville

CVG Cincinnati Cinci./N. Kentucky - GSP Greenville

CVGGSP

Cincinnati Cinci./N. Kentucky

Fri 12/11

6:45 pm-11:47 pm

1 stop5h 02m

Greenville

Mon 12/14

5:40 am-11:25 am

1 stop5h 45m

$237

ColumbusGreenville

CMH Columbus - GSP Greenville

CMHGSP

Columbus

Mon 11/23

7:05 am-11:07 am

1 stop4h 02m

Greenville

Mon 11/30

7:00 am-12:01 pm

1 stop5h 01m

$237

CincinnatiGreenville

CVG Cincinnati Cinci./N. Kentucky - GSP Greenville

CVGGSP

Cincinnati Cinci./N. Kentucky

Fri 1/8

8:30 am-6:15 pm

2 stops9h 45m

Greenville

Mon 1/11

8:25 am-12:35 pm

1 stop4h 10m

$242

CincinnatiGreenville

CVG Cincinnati Cinci./N. Kentucky - GSP Greenville

CVGGSP

Cincinnati Cinci./N. Kentucky

Sat 1/9

6:08 am-11:37 am

1 stop5h 29m

Greenville

Mon 1/11

2:57 pm-7:56 pm

1 stop4h 59m

$270

ClevelandGreenville

CLE Cleveland Hopkins Intl - GSP Greenville

CLEGSP

Cleveland Hopkins Intl

Wed 2/3

8:15 am-6:15 pm

2 stops10h 00m

Greenville

Mon 2/8

7:30 am-5:10 pm

2 stops9h 40m

$343

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Ohio to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Greenville?

The month of September is another great option to travel to Greenville, with average flight prices from Ohio averaging around $320.

What is the cheapest Ohio to Greenville flight route?

Fly from Columbus to Greenville for the best Ohio - Greenville flight prices

What cabin class options are available on Ohio to Greenville flights?

There are 2 cabin classes available to choose from on Ohio to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Ohio to Greenville flights?

No. A direct flight is the cheapest option for a flight between Ohio to Greenville.

Cheap Ohio to Greenville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Ohio to Greenville

Best Price Found	$69
Fastest flight time	1h 20m
Direct flights	Tue and Sat
Airports in Greenville	1 airport

The best one-way flight to Greenville from Ohio in the past 72 hours is $69. The best round-trip flight deal from Ohio to Greenville found on momondo in the last 72 hours is $123.

The fastest flight from Ohio to Greenville takes 1h 20m

Direct flights go from Ohio to Greenville on Tuesday and Saturday. The only airline offering direct flights is Breeze Airways.

There is 1 airport in Greenville. From Ohio there are direct flights to Greenville (GSP).

Search flight deals

Frequently asked questions about flying from Ohio to Greenville

When did momondo last update prices for flights from Ohio to Greenville Airport?
Prices for flights from Ohio to Greenville Airport are refreshed on a daily basis.
How many operators does momondo search for flights from Ohio to Greenville Airport?
There are 5 operators available for flights from Ohio to Greenville Airport as of November 2026.
How old do you have to be to fly from Ohio to Greenville Airport?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Ohio to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The travel and health documents you'll need for your trip to Greenville Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Greenville Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Ohio to Greenville?
momondo data reveals that the most frequently booked plane model on the route from Ohio to Greenville is Airbus A320-100/200, representing 22.54% of all bookings. The subsequent popular models are Airbus A220-300 at 21.83%, Boeing 737 MAX 8 at 20.42%, and Airbus A320neo at 11.27%.

Best airlines flying from Ohio to Greenville

Compare and see reviews for airlines that fly from Ohio to Greenville with momondo

Airline	Rating	Free Cancellation	Price
Breeze Airways	PriceFrom $71	Free Cancellation	Rating 8.2 323 reviews	Search Breeze Airways flights
Delta	PriceFrom $167	Free Cancellation	Rating 7.8 8,700 reviews	Search Delta flights
American Airlines	PriceFrom $232	Free Cancellation	Rating 7.0 12,224 reviews	Search American Airlines flights
Southwest	PriceFrom $249	Free Cancellation	Rating 8.0 4,219 reviews	Search Southwest flights
United Airlines	PriceFrom $266	Free Cancellation	Rating 7.3 10,471 reviews	Search United Airlines flights

Anderson

Greenwood

Simpsonville

Greer

Duncan

Seneca

Why use momondo?

Why should I use momondo to find a flight deal from Ohio to Greenville?

It is quick and easy to find Ohio to Greenville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Greenville that suits you.

Can I find flights from Ohio to Greenville with flexible booking policies on momondo?

Flights from Ohio to Greenville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Ohio to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Ohio to Greenville.

I’m not ready to book a flight from Ohio to Greenville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Ohio to Greenville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Greenville and let you know when they change.

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Cheap flights from Ohio to Greenville from $69

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Ohio to Greenville departing on 11/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Ohio to Greenville

Our best United Airlines deals on Ohio to Greenville flight tickets

American Airlines flights from Ohio to Greenville

Our best American Airlines deals on Ohio to Greenville flight tickets

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How to get the cheapest flight ticket from Ohio to Greenville

What is the cheapest month to fly to Greenville?

What is the cheapest Ohio to Greenville flight route?

What cabin class options are available on Ohio to Greenville flights?

Can stopping save me money on Ohio to Greenville flights?

What is the cheapest airline that flies from Ohio to Greenville?

What airlines fly to Greenville?

How many flights depart from Ohio to Greenville on average per week?

How long does it take to fly to Greenville?

Cheap Ohio to Greenville flight deals and tips

Best Price Found

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Airports in Greenville

Frequently asked questions about flying from Ohio to Greenville

Best airlines flying from Ohio to Greenville

Compare and see reviews for airlines that fly from Ohio to Greenville with momondo

Traveling to a place near Greenville?

Why use momondo?

An easier way to manage your Greenville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing South Carolina

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo

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List of cabin classes available on flights landing in Greenville. Availability may vary depending on flight origin and airline.

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