Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Chicago O'Hare Intl Airport to Knoxville from $98

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Knoxville departing on 11/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago O'Hare Intl Airport to Knoxville

Cheap round-trip flights

American Airlines Logo
2:07 pm - 4:53 pmORD-TYS
1h 46mnonstop
American Airlines Logo
7:59 am - 9:05 amTYS-ORD
2h 06mnonstop
$189American Airlines
Find Deal
Sat, Nov 8 - Tue, Nov 11
American Airlines Logo
9:43 am - 12:31 pmORD-TYS
1h 48mnonstop
American Airlines Logo
6:16 pm - 7:20 pmTYS-ORD
2h 04mnonstop
$190American Airlines
Find Deal
Wed, Oct 29 - Wed, Nov 5
United Airlines Logo
8:00 pm - 10:50 pmORD-TYS
1h 50mnonstop
United Airlines Logo
7:00 am - 7:55 amTYS-ORD
1h 55mnonstop
$192United Airlines
Find Deal
Sun, Oct 12 - Sun, Oct 19
United Airlines Logo
8:00 pm - 10:50 pmORD-TYS
1h 50mnonstop
United Airlines Logo
7:00 am - 7:55 amTYS-ORD
1h 55mnonstop
$194United Airlines
Find Deal
Fri, Oct 3 - Tue, Oct 7
Frontier Logo
6:50 am - 7:32 pmORD-TYS
11h 42m1 stop
Frontier Logo
7:17 pm - 10:41 amTYS-ORD
16h 24m2 stops
$201Frontier
Find Deal
Sun, Oct 26 - Thu, Oct 30
Multiple Airlines Logo
6:10 pm - 9:27 amORD-TYS
14h 17m1 stop
Multiple Airlines Logo
2:22 pm - 8:24 pmTYS-ORD
7h 02m1 stop
$208Multiple Airlines
Find Deal
Fri, Nov 7 - Mon, Nov 17
Delta Logo
1:25 pm - 9:13 pmORD-TYS
6h 48m1 stop
Delta Logo
8:05 pm - 12:01 amTYS-ORD
4h 56m1 stop
$209Delta
Find Deal
Sat, Nov 8 - Fri, Nov 14
Delta Logo
9:25 am - 4:55 pmORD-TYS
6h 30m1 stop
Delta Logo
8:10 pm - 11:58 pmTYS-ORD
4h 48m1 stop
$214Delta
Find Deal
Thu, Oct 2 - Mon, Oct 6
Frontier Logo
6:50 am - 7:32 pmORD-TYS
11h 42m1 stop
Frontier Logo
7:17 pm - 12:16 amTYS-ORD
29h 59m1 stop
$217Frontier
Find Deal
Sun, Oct 26 - Thu, Oct 30
Multiple Airlines Logo
6:10 pm - 9:27 amORD-TYS
14h 17m1 stop
Multiple Airlines Logo
5:38 pm - 11:42 pmTYS-ORD
7h 04m1 stop
$221Multiple Airlines
Find Deal
Fri, Nov 7 - Thu, Nov 13

United Airlines flights from Chicago O'Hare Intl Airport to Knoxville

Our best United Airlines deals on Chicago O'Hare Intl Airport to Knoxville flight tickets
United Airlines
Oct 12
ORD8:00 pmChicago O'Hare Intl
1h 50m
TYS10:50 pmKnoxville McGhee Tyson
Oct 19
TYS7:00 amKnoxville McGhee Tyson
1h 55m
ORD7:55 amChicago O'Hare Intl
$192
Find similar
United Airlines
Oct 3
ORD8:00 pmChicago O'Hare Intl
1h 50m
TYS10:50 pmKnoxville McGhee Tyson
Oct 7
TYS7:00 amKnoxville McGhee Tyson
1h 55m
ORD7:55 amChicago O'Hare Intl
$194
Find similar
United Airlines
Oct 7
ORD7:15 amChicago O'Hare Intl
1h 55m
TYS10:10 amKnoxville McGhee Tyson
Oct 17
TYS7:00 amKnoxville McGhee Tyson
1h 55m
ORD7:55 amChicago O'Hare Intl
$211
Find similar

Delta flights from Chicago O'Hare Intl Airport to Knoxville

Our best Delta deals on Chicago O'Hare Intl Airport to Knoxville flight tickets
Delta
Nov 8
ORD1:25 pmChicago O'Hare Intl
6h 48m
1 stop
TYS9:13 pmKnoxville McGhee Tyson
Nov 14
TYS8:05 pmKnoxville McGhee Tyson
4h 56m
1 stop
ORD12:01 amChicago O'Hare Intl
$209
Find similar
Delta
Oct 2
ORD9:25 amChicago O'Hare Intl
6h 30m
1 stop
TYS4:55 pmKnoxville McGhee Tyson
Oct 6
TYS8:10 pmKnoxville McGhee Tyson
4h 48m
1 stop
ORD11:58 pmChicago O'Hare Intl
$214
Find similar
Delta
Oct 3
ORD12:55 pmChicago O'Hare Intl
6h 44m
1 stop
TYS8:39 pmKnoxville McGhee Tyson
Oct 7
TYS5:44 amKnoxville McGhee Tyson
3h 48m
1 stop
ORD8:32 amChicago O'Hare Intl
$254
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 11/8

2:07 pm-4:53 pm

Nonstop1h 46m

Knoxville McGhee Tyson

Tue 11/11

7:59 am-9:05 am

Nonstop2h 06m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 10/29

9:43 am-12:31 pm

Nonstop1h 48m

Knoxville McGhee Tyson

Wed 11/5

6:16 pm-7:20 pm

Nonstop2h 04m

$190

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sun 10/12

8:00 pm-10:50 pm

Nonstop1h 50m

Knoxville McGhee Tyson

Sun 10/19

7:00 am-7:55 am

Nonstop1h 55m

$192

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 10/3

8:00 pm-10:50 pm

Nonstop1h 50m

Knoxville McGhee Tyson

Tue 10/7

7:00 am-7:55 am

Nonstop1h 55m

$194

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sun 10/26

6:50 am-7:32 pm

1 stop11h 42m

Knoxville McGhee Tyson

Thu 10/30

7:17 pm-10:41 am

2 stops16h 24m

$201

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 11/7

6:10 pm-9:27 am

1 stop14h 17m

Knoxville McGhee Tyson

Mon 11/17

2:22 pm-8:24 pm

1 stop7h 02m

$208

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 11/8

1:25 pm-9:13 pm

1 stop6h 48m

Knoxville McGhee Tyson

Fri 11/14

8:05 pm-12:01 am

1 stop4h 56m

$209

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 10/2

9:25 am-4:55 pm

1 stop6h 30m

Knoxville McGhee Tyson

Mon 10/6

8:10 pm-11:58 pm

1 stop4h 48m

$214

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sun 10/26

6:50 am-7:32 pm

1 stop11h 42m

Knoxville McGhee Tyson

Thu 10/30

7:17 pm-12:16 am

1 stop29h 59m

$217

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 11/7

6:10 pm-9:27 am

1 stop14h 17m

Knoxville McGhee Tyson

Thu 11/13

5:38 pm-11:42 pm

1 stop7h 04m

$221

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from Chicago O'Hare Intl Airport, with most prices found around $249. If you aren’t able to travel during the month of February, then book flights to Knoxville from Chicago O'Hare Intl Airport during August instead. Flights to Knoxville in August, while not as cheap as those in February, still average around $270.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Chicago O'Hare Intl Airport to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $266. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Chicago O'Hare Intl Airport to Knoxville for around $313.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Chicago O'Hare Intl Airport to Knoxville when you can find flight prices for as low as $267. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the morning when prices are around $293.

What is the cheapest Chicago O'Hare Intl to Knoxville McGhee Tyson flight route?

Fly from Chicago O'Hare Intl to Knoxville McGhee Tyson for the best Chicago O'Hare Intl - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $305 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Chicago O'Hare Intl Airport for as low as $222 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Knoxville McGhee Tyson flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Chicago O'Hare Intl Airport to Knoxville flight prices changed over time?

As of September 2025, prices for Chicago O'Hare Intl Airport to Knoxville flights are approximately 10% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Knoxville (ORD to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Knoxville

Best Price Found

$128

Fastest flight time

1h 40m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Chicago O'Hare Intl Airport in the past 72 hours is $128. The best round-trip flight deal from Chicago O'Hare Intl Airport to Knoxville found on momondo in the last 72 hours is $250.
The fastest flight from Chicago O'Hare Intl Airport to Knoxville takes 1h 40m
Direct flights go from Chicago O'Hare Intl Airport to Knoxville every day.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • How far is Chicago O'Hare Intl to Knoxville McGhee Tyson by plane?

    There are 467.2 mi between Chicago O'Hare Intl and Knoxville McGhee Tyson. Flights usually cover this in 1h 40m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Knoxville?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Knoxville?

Best airlines flying from Chicago O'Hare Intl Airport to Knoxville

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $180Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $190Free CancellationRating
7.4
8,929 reviews
Search United Airlines flights

  • United Airlines Flights From Chicago O'Hare Intl Airport to Knoxville

    United Airlines operates around 22 flights from Chicago O'Hare Intl Airport to Knoxville every week. The average price of these flights found in the last 72 hours has been $335, but momondo users have found United Airlines deals from Chicago O'Hare Intl Airport to Knoxville from as low as $190 round-trip. United Airlines has been scored 7.4/10 in 8,929 reviews.

  • American Airlines Flights From Chicago O'Hare Intl Airport to Knoxville

    American Airlines is also a popular choice for this route. American Airlines flight deals for Chicago O'Hare Intl Airport to Knoxville start from as low as $180 round-trip, depending on your selected dates, with average American Airlines deals seen on momondo around $300. American Airlines operates 17 flights to Knoxville from Chicago O'Hare Intl Airport in an average week. Users have rated it 7.2/10 across 10,000 reviews.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Newport
Lenoir City
Oak Ridge
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?

Flights from Chicago to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Knoxville?

Once all potential Chicago to Knoxville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 10/16
Thu 10/23
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States