Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Chicago O'Hare Intl Airport to Knoxville from $96

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Knoxville departing on 7/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Chicago O'Hare Intl Airport to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
2:00 pm - 7:38 pm
ORD
-
TYS
4h 38m
1 stop
Delta Logo
5:30 am - 8:34 am
TYS
-
ORD
4h 04m
1 stop
$217Delta
Fri, Sep 11 - Sun, Sep 13
Multiple Airlines Logo
8:05 am - 10:04 am
ORD
-
TYS
24h 59m
1 stop
Multiple Airlines Logo
3:49 pm - 1:00 pm
TYS
-
ORD
22h 11m
1 stop
$224Multiple Airlines
Wed, Aug 19 - Wed, Aug 26
Multiple Airlines Logo
8:05 am - 10:04 am
ORD
-
TYS
24h 59m
1 stop
Multiple Airlines Logo
5:21 pm - 3:26 pm
TYS
-
ORD
23h 05m
1 stop
$243Multiple Airlines
Sat, Sep 5 - Thu, Sep 10
Frontier Logo
9:57 pm - 7:24 pm
ORD
-
TYS
20h 27m
1 stop
Frontier Logo
8:19 pm - 8:52 pm
TYS
-
ORD
25h 33m
1 stop
$245Frontier
Tue, Jul 14 - Fri, Jul 17
Multiple Airlines Logo
8:05 am - 12:06 pm
ORD
-
TYS
27h 01m
1 stop
Multiple Airlines Logo
6:29 pm - 11:10 pm
TYS
-
ORD
29h 41m
1 stop
$247Multiple Airlines
Tue, Aug 4 - Fri, Aug 7
Multiple Airlines Logo
8:05 am - 8:32 am
ORD
-
TYS
23h 27m
1 stop
Multiple Airlines Logo
6:29 pm - 11:10 pm
TYS
-
ORD
29h 41m
1 stop
$248Multiple Airlines
Fri, Jul 31 - Fri, Aug 7
United Airlines Logo
5:55 pm - 8:44 pm
ORD
-
TYS
1h 49mnonstop
United Airlines Logo
6:00 am - 6:59 am
TYS
-
ORD
1h 59mnonstop
$249United Airlines
Fri, Jul 17 - Sun, Jul 19
Frontier Logo
9:57 pm - 7:24 pm
ORD
-
TYS
20h 27m
1 stop
Frontier Logo
8:19 pm - 8:52 pm
TYS
-
ORD
25h 33m
1 stop
$250Frontier
Thu, Jul 23 - Mon, Jul 27
Multiple Airlines Logo
5:30 pm - 11:12 pm
ORD
-
TYS
28h 42m
1 stop
Multiple Airlines Logo
3:56 pm - 9:11 am
TYS
-
ORD
18h 15m
1 stop
$256Multiple Airlines
Thu, Aug 13 - Sun, Aug 16
United Airlines Logo
5:55 pm - 8:44 pm
ORD
-
TYS
1h 49mnonstop
United Airlines Logo
6:00 am - 6:59 am
TYS
-
ORD
1h 59mnonstop
$258United Airlines
Thu, Jul 16 - Thu, Jul 23

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Delta flights from Chicago O'Hare Intl Airport to Knoxville

Our best Delta deals on Chicago O'Hare Intl Airport to Knoxville flight tickets
Delta
Sep 11
ORD2:00 pmChicago O'Hare Intl
4h 38m
1 stop
TYS7:38 pmKnoxville McGhee Tyson
Sep 13
TYS5:30 amKnoxville McGhee Tyson
4h 04m
1 stop
ORD8:34 amChicago O'Hare Intl
$217
Delta
Aug 5
ORD10:33 amChicago O'Hare Intl
3h 57m
1 stop
TYS3:30 pmKnoxville McGhee Tyson
Aug 8
TYS6:00 amKnoxville McGhee Tyson
4h 40m
1 stop
ORD9:40 amChicago O'Hare Intl
$269
Delta
Jul 2
ORD1:40 pmChicago O'Hare Intl
7h 01m
1 stop
TYS9:41 pmKnoxville McGhee Tyson
Jul 9
TYS3:59 pmKnoxville McGhee Tyson
5h 32m
1 stop
ORD8:31 pmChicago O'Hare Intl
$284

Frontier flights from Chicago O'Hare Intl Airport to Knoxville

Our best Frontier deals on Chicago O'Hare Intl Airport to Knoxville flight tickets
Frontier
Jul 14
ORD9:57 pmChicago O'Hare Intl
20h 27m
1 stop
TYS7:24 pmKnoxville McGhee Tyson
Jul 17
TYS8:19 pmKnoxville McGhee Tyson
25h 33m
1 stop
ORD8:52 pmChicago O'Hare Intl
$245
Frontier
Jul 23
ORD9:57 pmChicago O'Hare Intl
20h 27m
1 stop
TYS7:24 pmKnoxville McGhee Tyson
Jul 27
TYS8:19 pmKnoxville McGhee Tyson
25h 33m
1 stop
ORD8:52 pmChicago O'Hare Intl
$250
Frontier
Jul 23
ORD9:57 pmChicago O'Hare Intl
20h 27m
1 stop
TYS7:24 pmKnoxville McGhee Tyson
Jul 27
TYS8:19 pmKnoxville McGhee Tyson
25h 33m
1 stop
ORD8:52 pmChicago O'Hare Intl
$298

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 22, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 9/11

2:00 pm-7:38 pm

1 stop4h 38m

Knoxville McGhee Tyson

Sun 9/13

5:30 am-8:34 am

1 stop4h 04m

$217

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Wed 8/19

8:05 am-10:04 am

1 stop24h 59m

Knoxville McGhee Tyson

Wed 8/26

3:49 pm-1:00 pm

1 stop22h 11m

$224

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Sat 9/5

8:05 am-10:04 am

1 stop24h 59m

Knoxville McGhee Tyson

Thu 9/10

5:21 pm-3:26 pm

1 stop23h 05m

$243

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 7/14

9:57 pm-7:24 pm

1 stop20h 27m

Knoxville McGhee Tyson

Fri 7/17

8:19 pm-8:52 pm

1 stop25h 33m

$245

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Tue 8/4

8:05 am-12:06 pm

1 stop27h 01m

Knoxville McGhee Tyson

Fri 8/7

6:29 pm-11:10 pm

1 stop29h 41m

$247

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 7/31

8:05 am-8:32 am

1 stop23h 27m

Knoxville McGhee Tyson

Fri 8/7

6:29 pm-11:10 pm

1 stop29h 41m

$248
Quickest round-trip

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 7/17

5:55 pm-8:44 pm

Nonstop1h 49m

Knoxville McGhee Tyson

Sun 7/19

6:00 am-6:59 am

Nonstop1h 59m

$249

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 7/23

9:57 pm-7:24 pm

1 stop20h 27m

Knoxville McGhee Tyson

Mon 7/27

8:19 pm-8:52 pm

1 stop25h 33m

$250

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 8/13

5:30 pm-11:12 pm

1 stop28h 42m

Knoxville McGhee Tyson

Sun 8/16

3:56 pm-9:11 am

1 stop18h 15m

$256

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 7/16

5:55 pm-8:44 pm

Nonstop1h 49m

Knoxville McGhee Tyson

Thu 7/23

6:00 am-6:59 am

Nonstop1h 59m

$258

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Knoxville from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago O'Hare Intl Airport and Knoxville?

What is the cheapest month to fly to Knoxville?

The month of November is, on average, the cheapest month to fly to Knoxville from Chicago O'Hare Intl Airport, with most prices found around $283. If you aren’t able to travel during the month of November, then book flights to Knoxville from Chicago O'Hare Intl Airport during August instead. Flights to Knoxville in August, while not as cheap as those in November, still average around $284.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Chicago O'Hare Intl Airport to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $270. When flying out on a Monday, the most expensive travel day of the week, you can expect to see flight prices from Chicago O'Hare Intl Airport to Knoxville for around $340.

What is the cheapest time of day to depart on your flight to Knoxville?

At noon is the cheapest time of day to fly from Chicago O'Hare Intl Airport to Knoxville when you can find flight prices for as low as $236. Flying to Knoxville at noon is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $338.

What is the cheapest Chicago O'Hare Intl to Knoxville McGhee Tyson flight route?

Fly from Chicago O'Hare Intl to Knoxville McGhee Tyson for the best Chicago O'Hare Intl - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight from Chicago O'Hare Intl Airport to Knoxville?

You are more likely to see cheaper flights to Knoxville from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $326 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Chicago O'Hare Intl Airport for as low as $242 on momondo.

What cabin class options are available on Chicago O'Hare Intl Airport to Knoxville flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl Airport to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Knoxville flights?

You could potentially save up to 12% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Knoxville flight.

How have Chicago O'Hare Intl Airport to Knoxville flight prices changed over time?

As of June 2026, prices for Chicago O'Hare Intl Airport to Knoxville flights are approximately 97% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Knoxville (ORD to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Knoxville

Best Price Found

$173

Fastest flight time

1h 39m

Direct flights

Every day

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Chicago O'Hare Intl Airport in the past 72 hours is $173. The best round-trip flight deal from Chicago O'Hare Intl Airport to Knoxville found on momondo in the last 72 hours is $272.
The fastest flight from Chicago O'Hare Intl Airport to Knoxville takes 1h 39m
Direct flights go from Chicago O'Hare Intl Airport to Knoxville every day.
There is 1 airport in Knoxville. From Chicago O'Hare Intl Airport there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from Chicago O'Hare Intl Airport to Knoxville

  • How far is Chicago O'Hare Intl to Knoxville McGhee Tyson by plane?

    There are 467.2 mi between Chicago O'Hare Intl and Knoxville McGhee Tyson. Flights usually cover this in 1h 39m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Knoxville?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Knoxville?

Best airlines flying from Chicago O'Hare Intl Airport to Knoxville

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $189Free CancellationRating
7.4
9,875 reviews
Search United Airlines flights
American AirlinesPriceFrom $190Free CancellationRating
7.1
11,739 reviews
Search American Airlines flights

  • United Airlines Flights From Chicago O'Hare Intl Airport to Knoxville

    United Airlines operates around 21 flights from Chicago O'Hare Intl Airport to Knoxville every week. The average price of these flights found in the last 72 hours has been $321, but momondo users have found United Airlines deals from Chicago O'Hare Intl Airport to Knoxville from as low as $189 round-trip. United Airlines has been scored 7.4/10 in 9,868 reviews.

  • American Airlines Flights From Chicago O'Hare Intl Airport to Knoxville

    American Airlines is also a popular choice for this route. American Airlines flight deals for Chicago O'Hare Intl Airport to Knoxville start from as low as $190 round-trip, depending on your selected dates, with average American Airlines deals seen on momondo around $331. American Airlines operates 24 flights to Knoxville from Chicago O'Hare Intl Airport in an average week. Users have rated it 7.1/10 across 11,722 reviews.

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Alcoa
Maryville
Murphy
Crossville
Oak Ridge
Lenoir City
Kodak
Newport
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Knoxville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Knoxville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Knoxville with flexible booking policies on momondo?

Flights from Chicago to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Chicago to Knoxville?

Once all potential Chicago to Knoxville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Chicago to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Chicago to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Wed 7/22
Wed 7/29
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States