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Cheap flights from Chicago O'Hare Intl Airport to Greenville from $101

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Chicago O'Hare Intl Airport to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:11 am - 5:14 pmORD  Chicago O'Hare Intl-GSP Greenville
9h 03m1 stop Fort Lauderdale
Multiple Airlines Logo
12:29 pm - 3:20 pmGSP  Greenville-ORD Chicago O'Hare Intl
27h 51m1 stop Fort Lauderdale
$195Multiple Airlines
Tue, Sep 22 - Tue, Sep 29
Multiple Airlines Logo
7:11 am - 9:27 amORD  Chicago O'Hare Intl-GSP Greenville
25h 16m2 stops Fort Lauderdale Tampa
Multiple Airlines Logo
3:20 pm - 3:36 pmGSP  Greenville-ORD Chicago O'Hare Intl
25h 16m1 stop Fort Lauderdale
$201Multiple Airlines
Sat, Oct 3 - Mon, Oct 19
Multiple Airlines Logo
7:11 am - 12:39 pmORD  Chicago O'Hare Intl-GSP Greenville
28h 28m1 stop Fort Lauderdale
Multiple Airlines Logo
3:20 pm - 3:36 pmGSP  Greenville-ORD Chicago O'Hare Intl
25h 16m1 stop Fort Lauderdale
$208Multiple Airlines
Sat, Oct 3 - Mon, Oct 19
Multiple Airlines Logo
7:11 am - 9:27 amORD  Chicago O'Hare Intl-GSP Greenville
25h 16m2 stops Fort Lauderdale Tampa
Multiple Airlines Logo
12:11 pm - 3:36 pmGSP  Greenville-ORD Chicago O'Hare Intl
28h 25m1 stop Fort Lauderdale
$224Multiple Airlines
Sat, Oct 3 - Fri, Oct 9
American Airlines Logo
8:00 am - 11:03 amORD  Chicago O'Hare Intl-GSP Greenville
2h 03mnonstop
American Airlines Logo
6:43 pm - 8:13 pmGSP  Greenville-ORD Chicago O'Hare Intl
2h 30mnonstop
$279American Airlines
Sat, Oct 3 - Wed, Oct 7
American Airlines Logo
8:00 am - 11:03 amORD  Chicago O'Hare Intl-GSP Greenville
2h 03mnonstop
American Airlines Logo
7:24 am - 8:50 amGSP  Greenville-ORD Chicago O'Hare Intl
2h 26mnonstop
$279American Airlines
Wed, Sep 23 - Wed, Sep 30
United Airlines Logo
6:29 am - 9:35 amORD  Chicago O'Hare Intl-GSP Greenville
2h 06mnonstop
United Airlines Logo
5:46 pm - 7:05 pmGSP  Greenville-ORD Chicago O'Hare Intl
2h 19mnonstop
$279United Airlines
Tue, Sep 22 - Tue, Sep 29
United Airlines Logo
6:15 pm - 9:18 pmORD  Chicago O'Hare Intl-GSP Greenville
2h 03mnonstop
United Airlines Logo
6:10 pm - 7:32 pmGSP  Greenville-ORD Chicago O'Hare Intl
2h 22mnonstop
$279United Airlines
Tue, Sep 22 - Wed, Sep 23
American Airlines Logo
8:09 am - 11:08 amORD  Chicago O'Hare Intl-GSP Greenville
1h 59mnonstop
American Airlines Logo
11:38 am - 12:54 pmGSP  Greenville-ORD Chicago O'Hare Intl
2h 16mnonstop
$279American Airlines
Mon, Oct 19 - Sat, Oct 24
United Airlines Logo
6:29 am - 9:35 amORD  Chicago O'Hare Intl-GSP Greenville
2h 06mnonstop
United Airlines Logo
2:16 pm - 3:30 pmGSP  Greenville-ORD Chicago O'Hare Intl
2h 14mnonstop
$279United Airlines
Tue, Sep 22 - Sat, Sep 26

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American Airlines flights from Chicago O'Hare Intl Airport to Greenville

Our best American Airlines deals on Chicago O'Hare Intl Airport to Greenville flight tickets
American Airlines
Sep 24
ORD6:49 pmChicago O'Hare Intl
2h 05m
GSP9:54 pmGreenville
Sep 28
GSP6:23 pmGreenville
2h 36m
ORD7:59 pmChicago O'Hare Intl
$280
American Airlines
Sep 28
ORD9:40 amChicago O'Hare Intl
2h 01m
GSP12:41 pmGreenville
Oct 27
GSP6:43 pmGreenville
2h 30m
ORD8:13 pmChicago O'Hare Intl
$281
American Airlines
Sep 25
ORD9:40 amChicago O'Hare Intl
2h 01m
GSP12:41 pmGreenville
Sep 28
GSP7:41 pmGreenville
5h 18m
1 stop
ORD11:59 pmChicago O'Hare Intl
$299

United Airlines flights from Chicago O'Hare Intl Airport to Greenville

Our best United Airlines deals on Chicago O'Hare Intl Airport to Greenville flight tickets
United Airlines
Oct 10
ORD5:59 pmChicago O'Hare Intl
1h 59m
GSP8:58 pmGreenville
Oct 19
GSP6:20 amGreenville
2h 09m
ORD7:29 amChicago O'Hare Intl
$279
United Airlines
Sep 24
ORD6:55 amChicago O'Hare Intl
2h 03m
GSP9:58 amGreenville
Sep 27
GSP6:20 amGreenville
2h 09m
ORD7:29 amChicago O'Hare Intl
$289
United Airlines
Oct 8
ORD6:17 pmChicago O'Hare Intl
2h 00m
GSP9:17 pmGreenville
Oct 13
GSP6:20 amGreenville
2h 09m
ORD7:29 amChicago O'Hare Intl
$303

momondo Fare Finder

 
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoGreenville

ORD Chicago O'Hare Intl - GSP Greenville

ORDGSP

Chicago O'Hare Intl

Tue 9/22

7:11 am-5:14 pm

1 stop9h 03m

Greenville

Tue 9/29

12:29 pm-3:20 pm

1 stop27h 51m

$195

ChicagoGreenville

ORD Chicago O'Hare Intl - GSP Greenville

ORDGSP

Chicago O'Hare Intl

Sat 10/3

7:11 am-9:27 am

2 stops25h 16m

Greenville

Mon 10/19

3:20 pm-3:36 pm

1 stop25h 16m

$201

ChicagoGreenville

ORD Chicago O'Hare Intl - GSP Greenville

ORDGSP

Chicago O'Hare Intl

Sat 10/3

7:11 am-12:39 pm

1 stop28h 28m

Greenville

Mon 10/19

3:20 pm-3:36 pm

1 stop25h 16m

$208

ChicagoGreenville

ORD Chicago O'Hare Intl - GSP Greenville

ORDGSP

Chicago O'Hare Intl

Sat 10/3

7:11 am-9:27 am

2 stops25h 16m

Greenville

Fri 10/9

12:11 pm-3:36 pm

1 stop28h 25m

$224

ChicagoGreenville

ORD Chicago O'Hare Intl - GSP Greenville

ORDGSP

Chicago O'Hare Intl

Sat 10/3

8:00 am-11:03 am

Nonstop2h 03m

Greenville

Wed 10/7

6:43 pm-8:13 pm

Nonstop2h 30m

$279

ChicagoGreenville

ORD Chicago O'Hare Intl - GSP Greenville

ORDGSP

Chicago O'Hare Intl

Wed 9/23

8:00 am-11:03 am

Nonstop2h 03m

Greenville

Wed 9/30

7:24 am-8:50 am

Nonstop2h 26m

$279

ChicagoGreenville

ORD Chicago O'Hare Intl - GSP Greenville

ORDGSP

Chicago O'Hare Intl

Tue 9/22

6:29 am-9:35 am

Nonstop2h 06m

Greenville

Tue 9/29

5:46 pm-7:05 pm

Nonstop2h 19m

$279

ChicagoGreenville

ORD Chicago O'Hare Intl - GSP Greenville

ORDGSP

Chicago O'Hare Intl

Tue 9/22

6:15 pm-9:18 pm

Nonstop2h 03m

Greenville

Wed 9/23

6:10 pm-7:32 pm

Nonstop2h 22m

$279
Quickest round-trip

ChicagoGreenville

ORD Chicago O'Hare Intl - GSP Greenville

ORDGSP

Chicago O'Hare Intl

Mon 10/19

8:09 am-11:08 am

Nonstop1h 59m

Greenville

Sat 10/24

11:38 am-12:54 pm

Nonstop2h 16m

$279

ChicagoGreenville

ORD Chicago O'Hare Intl - GSP Greenville

ORDGSP

Chicago O'Hare Intl

Tue 9/22

6:29 am-9:35 am

Nonstop2h 06m

Greenville

Sat 9/26

2:16 pm-3:30 pm

Nonstop2h 14m

$279

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago O'Hare Intl Airport and Greenville?

Prices are currently low for flights on this route.

Typical prices usually range from $269 to $327.
The lowest price recently found on this route was $195.

What is the cheapest month to fly to Greenville?

The month of February is another great option to travel to Greenville, with average flight prices from Chicago O'Hare Intl Airport averaging around $284.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Saturday is the cheapest day to fly to Greenville from Chicago O'Hare Intl Airport. The lowest ticket price found for a Saturday departure recently was $282. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $400. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Chicago O'Hare Intl Airport to Greenville during this time can be as low as $313. Flights to Greenville are more costly in the evening, with an average ticket price of $330. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago O'Hare Intl to Greenville flight route?

Fly from Chicago O'Hare Intl to Greenville for the best Chicago O'Hare Intl - Greenville flight prices

How far in advance should I book a flight from Chicago O'Hare Intl Airport to Greenville?

You are more likely to see cheaper flights to Greenville from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $329 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Chicago O'Hare Intl Airport for as low as $222 on momondo.

What cabin class options are available on Chicago O'Hare Intl Airport to Greenville flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl Airport to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Greenville flights?

No. A direct flight is the cheapest option for a flight between Chicago O'Hare Intl Airport to Greenville.

How have Chicago O'Hare Intl Airport to Greenville flight prices changed over time?

As of August 2026, prices for Chicago O'Hare Intl Airport to Greenville flights are approximately 24% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Greenville (ORD to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Greenville

Best Price Found

$101

Fastest flight time

1h 56m

Direct flights

Every day

Airports in Greenville

1 airport
The best one-way flight to Greenville from Chicago O'Hare Intl Airport in the past 72 hours is $101. The best round-trip flight deal from Chicago O'Hare Intl Airport to Greenville found on momondo in the last 72 hours is $195.
The fastest flight from Chicago O'Hare Intl Airport to Greenville takes 1h 56m
Direct flights go from Chicago O'Hare Intl Airport to Greenville every day.
There is 1 airport in Greenville. From Chicago O'Hare Intl Airport there are direct flights to Greenville (GSP).
Search flight deals

Frequently asked questions about flying from Chicago O'Hare Intl Airport to Greenville

  • How far is Chicago O'Hare Intl to Greenville by plane?

    Chicago O'Hare Intl and Greenville are 575.0 mi apart from one another. Typically, this will take 1h 56m by plane in normal conditions.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Greenville Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Greenville Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Greenville?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Greenville?

Best airlines flying from Chicago O'Hare Intl Airport to Greenville

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $202Free CancellationRating
7.1
12,019 reviews
Search American Airlines flights
United AirlinesPriceFrom $212Free CancellationRating
7.4
10,138 reviews
Search United Airlines flights

  • United Airlines Flights From Chicago O'Hare Intl Airport to Greenville

    United Airlines flight deals from Chicago O'Hare Intl Airport to Greenville start from $212 round-trip. Over the 19 United Airlines flights for this route in a normal week, average airfare is usually $318 round-trip - but some users have found much cheaper deals with momondo.

  • American Airlines Flights From Chicago O'Hare Intl Airport to Greenville

    The best American Airlines deal for Chicago O'Hare Intl Airport to Greenville flight tickets found on momondo in the last 72 hours was $202, round-trip. It should be noted that an average American Airlines flight deal for this route in this time was higher, at $306 round-trip. American Airlines operates 21 flights out of Chicago O'Hare Intl Airport into Greenville in an average week, so prices vary by time and availability. 12,019 American Airlines reviews by users on momondo have scored the airline at 7.1/10.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Greenville?

momondo provides multiple filters to help you find the best flight to Greenville from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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