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Cheap flights from Chicago O'Hare Intl Airport to Greenville from $94

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Greenville departing on 12/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:36 pm - 9:45 pmORD-GSP
2h 09mnonstop
American Airlines Logo
6:00 am - 7:13 amGSP-ORD
2h 13mnonstop
$209American Airlines
Find Deal
Wed, Dec 10 - Tue, Dec 16
United Airlines Logo
1:55 pm - 4:54 pmORD-GSP
1h 59mnonstop
United Airlines Logo
7:45 pm - 11:44 pmGSP-ORD
4h 59m1 stop
$212United Airlines
Find Deal
Wed, Apr 15 - Mon, Apr 20
Delta Logo
5:30 am - 11:08 amORD-GSP
4h 38m1 stop
Delta Logo
5:59 pm - 10:34 pmGSP-ORD
5h 35m1 stop
$215Delta
Find Deal
Sat, Jan 17 - Tue, Jan 20
United Airlines Logo
8:50 am - 2:17 pmORD-GSP
4h 27m1 stop
United Airlines Logo
6:35 am - 7:56 amGSP-ORD
2h 21mnonstop
$219United Airlines
Find Deal
Sun, Dec 14 - Sun, Jan 11
Multiple Airlines Logo
4:01 pm - 9:51 amORD-GSP
40h 50m2 stops
Multiple Airlines Logo
4:40 pm - 3:02 pmGSP-ORD
23h 22m1 stop
$221Multiple Airlines
Find Deal
Wed, Dec 17 - Wed, Dec 24
Delta Logo
7:05 am - 2:03 pmORD-GSP
5h 58m1 stop
Delta Logo
7:46 pm - 11:56 pmGSP-ORD
5h 10m1 stop
$222Delta
Find Deal
Wed, Jan 21 - Sun, Jan 25
American Airlines Logo
4:46 pm - 7:37 pmORD-GSP
1h 51mnonstop
American Airlines Logo
8:07 pm - 9:25 pmGSP-ORD
2h 18mnonstop
$224American Airlines
Find Deal
Thu, Dec 18 - Sun, Dec 21
American Airlines Logo
8:14 am - 11:12 amORD-GSP
1h 58mnonstop
American Airlines Logo
10:43 am - 4:47 pmGSP-ORD
7h 04m1 stop
$227American Airlines
Find Deal
Wed, Dec 17 - Wed, Dec 24
Delta Logo
6:45 am - 2:38 pmORD-GSP
6h 53m1 stop
Delta Logo
7:25 am - 1:50 pmGSP-ORD
7h 25m1 stop
$229Delta
Find Deal
Wed, Dec 10 - Sun, Dec 14
United Airlines Logo
7:05 am - 10:09 amORD-GSP
2h 04mnonstop
United Airlines Logo
5:35 pm - 6:55 pmGSP-ORD
2h 20mnonstop
$231United Airlines
Find Deal
Wed, Apr 15 - Mon, Apr 20

American Airlines flights from Chicago O'Hare Intl Airport to Greenville

Our best American Airlines deals on Chicago O'Hare Intl Airport to Greenville flight tickets
American Airlines
Dec 10
ORD8:14 amChicago O'Hare Intl
1h 58m
GSP11:12 amGreenville
Dec 14
GSP8:14 pmGreenville
2h 16m
ORD9:30 pmChicago O'Hare Intl
$209
Find similar
American Airlines
Nov 27
ORD1:30 pmChicago O'Hare Intl
1h 55m
GSP4:25 pmGreenville
Dec 2
GSP8:14 pmGreenville
2h 16m
ORD9:30 pmChicago O'Hare Intl
$222
Find similar
American Airlines
Dec 18
ORD4:46 pmChicago O'Hare Intl
1h 51m
GSP7:37 pmGreenville
Dec 21
GSP8:07 pmGreenville
2h 18m
ORD9:25 pmChicago O'Hare Intl
$224
Find similar

United Airlines flights from Chicago O'Hare Intl Airport to Greenville

Our best United Airlines deals on Chicago O'Hare Intl Airport to Greenville flight tickets
United Airlines
Apr 15
ORD1:55 pmChicago O'Hare Intl
1h 59m
GSP4:54 pmGreenville
Apr 20
GSP7:45 pmGreenville
4h 59m
1 stop
ORD11:44 pmChicago O'Hare Intl
$212
Find similar
United Airlines
Dec 14
ORD8:50 amChicago O'Hare Intl
4h 27m
1 stop
GSP2:17 pmGreenville
Jan 11
GSP6:35 amGreenville
2h 21m
ORD7:56 amChicago O'Hare Intl
$219
Find similar
United Airlines
Apr 15
ORD7:05 amChicago O'Hare Intl
2h 04m
GSP10:09 amGreenville
Apr 20
GSP5:35 pmGreenville
2h 20m
ORD6:55 pmChicago O'Hare Intl
$231
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 19, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 12/10

6:36 pm-9:45 pm

Nonstop2h 09m

Greenville

Tue 12/16

6:00 am-7:13 am

Nonstop2h 13m

$209

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 4/15

1:55 pm-4:54 pm

Nonstop1h 59m

Greenville

Mon 4/20

7:45 pm-11:44 pm

1 stop4h 59m

$212

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 1/17

5:30 am-11:08 am

1 stop4h 38m

Greenville

Tue 1/20

5:59 pm-10:34 pm

1 stop5h 35m

$215

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sun 12/14

8:50 am-2:17 pm

1 stop4h 27m

Greenville

Sun 1/11

6:35 am-7:56 am

Nonstop2h 21m

$219

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 12/17

4:01 pm-9:51 am

2 stops40h 50m

Greenville

Wed 12/24

4:40 pm-3:02 pm

1 stop23h 22m

$221

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 1/21

7:05 am-2:03 pm

1 stop5h 58m

Greenville

Sun 1/25

7:46 pm-11:56 pm

1 stop5h 10m

$222

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 12/18

4:46 pm-7:37 pm

Nonstop1h 51m

Greenville

Sun 12/21

8:07 pm-9:25 pm

Nonstop2h 18m

$224

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 12/17

8:14 am-11:12 am

Nonstop1h 58m

Greenville

Wed 12/24

10:43 am-4:47 pm

1 stop7h 04m

$227

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 12/10

6:45 am-2:38 pm

1 stop6h 53m

Greenville

Sun 12/14

7:25 am-1:50 pm

1 stop7h 25m

$229

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 4/15

7:05 am-10:09 am

Nonstop2h 04m

Greenville

Mon 4/20

5:35 pm-6:55 pm

Nonstop2h 20m

$231

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Greenville from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of June is another great option to travel to Greenville, with average flight prices from Chicago O'Hare Intl Airport averaging around $281.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Saturday is the cheapest day to fly to Greenville from Chicago O'Hare Intl Airport. The lowest ticket price found for a Saturday departure recently was $287. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $415. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Chicago O'Hare Intl Airport to Greenville during this time can be as low as $305. Flights to Greenville are more costly in the evening, with an average ticket price of $318. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago O'Hare Intl to Greenville flight route?

Fly from Chicago O'Hare Intl to Greenville for the best Chicago O'Hare Intl - Greenville flight prices

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $310 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Chicago O'Hare Intl Airport for as low as $230 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Greenville flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Greenville flights?

You could potentially save up to 17% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Greenville flight.

How have Chicago O'Hare Intl Airport to Greenville flight prices changed over time?

As of November 2025, prices for Chicago O'Hare Intl Airport to Greenville flights are approximately 100% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Greenville (ORD to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Greenville

Best Price Found

$168

Fastest flight time

1h 50m

Direct flights

Every day

Airports in Greenville

1 airport
The best one-way flight to Greenville from Chicago O'Hare Intl Airport in the past 72 hours is $168. The best round-trip flight deal from Chicago O'Hare Intl Airport to Greenville found on momondo in the last 72 hours is $259.
The fastest flight from Chicago O'Hare Intl Airport to Greenville takes 1h 50m
Direct flights go from Chicago O'Hare Intl Airport to Greenville every day.
There is 1 airport near Greenville: Greenville (GSP)
Search flight deals

  • How far is Chicago O'Hare Intl to Greenville by plane?

    Chicago O'Hare Intl and Greenville are 575.0 mi apart from one another. Typically, this will take 1h 51m by plane in normal conditions.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Greenville Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Greenville Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Greenville?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Greenville?

Best airlines flying from Chicago O'Hare Intl Airport to Greenville

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $148Free CancellationRating
7.9
8,004 reviews
Search Delta flights
American AirlinesPriceFrom $202Free CancellationRating
7.2
11,046 reviews
Search American Airlines flights
United AirlinesPriceFrom $228Free CancellationRating
7.4
9,025 reviews
Search United Airlines flights

  • United Airlines Flights From Chicago O'Hare Intl Airport to Greenville

    United Airlines flight deals from Chicago O'Hare Intl Airport to Greenville start from $228 round-trip. Over the 19 United Airlines flights for this route in a normal week, average airfare is usually $370 round-trip - but some users have found much cheaper deals with momondo.

  • American Airlines Flights From Chicago O'Hare Intl Airport to Greenville

    The best American Airlines deal for Chicago O'Hare Intl Airport to Greenville flight tickets found on momondo in the last 72 hours was $202, round-trip. It should be noted that an average American Airlines flight deal for this route in this time was higher, at $286 round-trip. American Airlines operates 9 flights out of Chicago O'Hare Intl Airport into Greenville in an average week, so prices vary by time and availability. 11,046 American Airlines reviews by users on momondo have scored the airline at 7.2/10.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Greenville?

momondo provides multiple filters to help you find the best flight to Greenville from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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