Cheap flights from Chicago O'Hare Intl Airport to Greenville from $67

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Greenville departing on 9/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago O'Hare Intl Airport to Greenville

Cheap round-trip flights

Southwest Logo
1:50 pm - 7:55 pmORD-GSP
5h 05m1 stop
Southwest Logo
7:40 am - 12:45 pmGSP-ORD
6h 05m1 stop
$161Southwest
Find Deal
Tue, Sep 16 - Fri, Sep 26
Southwest Logo
1:50 pm - 9:25 pmORD-GSP
6h 35m1 stop
Southwest Logo
6:05 am - 11:50 amGSP-ORD
6h 45m1 stop
$167Southwest
Find Deal
Thu, Oct 16 - Wed, Oct 22
United Airlines Logo
1:55 pm - 4:54 pmORD-GSP
1h 59mnonstop
United Airlines Logo
10:42 am - 12:05 pmGSP-ORD
2h 23mnonstop
$177United Airlines
Find Deal
Tue, Aug 5 - Tue, Aug 12
United Airlines Logo
1:55 pm - 4:54 pmORD-GSP
1h 59mnonstop
United Airlines Logo
10:27 am - 4:52 pmGSP-ORD
7h 25m1 stop
$187United Airlines
Find Deal
Tue, Aug 5 - Tue, Aug 12
Delta Logo
2:00 pm - 9:37 pmORD-GSP
6h 37m1 stop
Delta Logo
7:50 pm - 11:56 pmGSP-ORD
5h 06m1 stop
$197Delta
Find Deal
Fri, Aug 8 - Fri, Aug 15
American Airlines Logo
4:24 pm - 7:16 pmORD-GSP
1h 52mnonstop
American Airlines Logo
7:33 am - 8:55 amGSP-ORD
2h 22mnonstop
$202American Airlines
Find Deal
Thu, Aug 14 - Tue, Aug 19
 Logo
5:05 am - 8:52 pmORD-GSP
14h 47m1 stop
 Logo
9:41 pm - 8:55 amGSP-ORD
12h 14m1 stop
Wed, Jul 30 - Wed, Aug 6
American Airlines Logo
4:24 pm - 7:16 pmORD-GSP
1h 52mnonstop
American Airlines Logo
7:37 am - 8:59 amGSP-ORD
2h 22mnonstop
$209American Airlines
Find Deal
Fri, Aug 15 - Sun, Aug 17
Delta Logo
5:45 am - 1:14 pmORD-GSP
6h 29m1 stop
Delta Logo
2:09 pm - 7:09 pmGSP-ORD
6h 00m1 stop
$223Delta
Find Deal
Mon, Aug 11 - Wed, Aug 13
 Logo
8:50 am - 8:52 pmORD-GSP
11h 02m2 stops
 Logo
9:41 pm - 8:55 amGSP-ORD
12h 14m1 stop
Wed, Jul 30 - Wed, Aug 6

American Airlines flights from Chicago O'Hare Intl Airport to Greenville

Our best American Airlines deals on Chicago O'Hare Intl Airport to Greenville flight tickets
American Airlines
Aug 14
ORD4:24 pmChicago O'Hare Intl
1h 52m
GSP7:16 pmGreenville
Aug 19
GSP7:33 amGreenville
2h 22m
ORD8:55 amChicago O'Hare Intl
American Airlines
Aug 15
ORD4:24 pmChicago O'Hare Intl
1h 52m
GSP7:16 pmGreenville
Aug 17
GSP7:37 amGreenville
2h 22m
ORD8:59 amChicago O'Hare Intl
American Airlines
Aug 1
ORD6:35 pmChicago O'Hare Intl
2h 01m
GSP9:36 pmGreenville
Aug 4
GSP6:32 pmGreenville
2h 08m
ORD7:40 pmChicago O'Hare Intl

United Airlines flights from Chicago O'Hare Intl Airport to Greenville

Our best United Airlines deals on Chicago O'Hare Intl Airport to Greenville flight tickets
United Airlines
Aug 5
ORD1:55 pmChicago O'Hare Intl
1h 59m
GSP4:54 pmGreenville
Aug 12
GSP10:42 amGreenville
2h 23m
ORD12:05 pmChicago O'Hare Intl
United Airlines
Aug 5
ORD1:55 pmChicago O'Hare Intl
1h 59m
GSP4:54 pmGreenville
Aug 12
GSP10:27 amGreenville
7h 25m
1 stop
ORD4:52 pmChicago O'Hare Intl
United Airlines
Sep 13
ORD11:20 amChicago O'Hare Intl
2h 01m
GSP2:21 pmGreenville
Sep 24
GSP9:35 amGreenville
2h 16m
ORD10:51 amChicago O'Hare Intl

See travel insights to Greenville from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of February is another great option to travel to Greenville, with average flight prices from Chicago O'Hare Intl Airport averaging around $298.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Saturday is the cheapest day to fly to Greenville from Chicago O'Hare Intl Airport. The lowest ticket price found for a Saturday departure recently was $304. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $401. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the evening. Flights from Chicago O'Hare Intl Airport to Greenville during this time can be as low as $298. Flights to Greenville are more costly at noon, with an average ticket price of $329. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago O'Hare Intl to Greenville flight route?

Fly from Chicago O'Hare Intl to Greenville for the best Chicago O'Hare Intl - Greenville flight prices

How far in advance should I book a flight to Greenville?

You are more likely to see cheaper flights to Greenville from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $315 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Chicago O'Hare Intl Airport for as low as $242 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Greenville flights?

There are 4 cabin classes available to choose from on Chicago O'Hare Intl to Greenville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Greenville flights?

You could potentially save up to 32% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Greenville flight.

How have Chicago O'Hare Intl Airport to Greenville flight prices changed over time?

As of July 2025, prices for Chicago O'Hare Intl Airport to Greenville flights are approximately 46% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Greenville (ORD to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Greenville

Best Price Found

$67

Fastest flight time

1h 51m

Direct flights

Every day

Airports in Greenville

1 airport
The best one-way flight to Greenville from Chicago O'Hare Intl Airport in the past 72 hours is $67. The best round-trip flight deal from Chicago O'Hare Intl Airport to Greenville found on momondo in the last 72 hours is $161.
The fastest flight from Chicago O'Hare Intl Airport to Greenville takes 1h 51m
Direct flights go from Chicago O'Hare Intl Airport to Greenville every day.
There is 1 airport near Greenville: Greenville (GSP)

  • How far is Chicago O'Hare Intl to Greenville by plane?

    Chicago O'Hare Intl and Greenville are 575.0 mi apart from one another. Typically, this will take 1h 51m by plane in normal conditions.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Greenville Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Greenville Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Greenville?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Greenville?


Best airlines flying from Chicago O'Hare Intl Airport to Greenville

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Greenville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $202Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $210Free CancellationRating
7.4
8,846 reviews
Search United Airlines flights
  • United Airlines Flights From Chicago O'Hare Intl Airport to Greenville

    United Airlines flight deals from Chicago O'Hare Intl Airport to Greenville start from $210 round-trip. Over the 15 United Airlines flights for this route in a normal week, average airfare is usually $366 round-trip - but some users have found much cheaper deals with momondo.

  • American Airlines Flights From Chicago O'Hare Intl Airport to Greenville

    The best American Airlines deal for Chicago O'Hare Intl Airport to Greenville flight tickets found on momondo in the last 72 hours was $202, round-trip. It should be noted that an average American Airlines flight deal for this route in this time was higher, at $297 round-trip. American Airlines operates 16 flights out of Chicago O'Hare Intl Airport into Greenville in an average week, so prices vary by time and availability. 10,000 American Airlines reviews by users on momondo have scored the airline at 7.2/10.


Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Seneca
Greer
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Greenville?

momondo provides multiple filters to help you find the best flight to Greenville from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.


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1 adult
Tue 7/15
Tue 7/22

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