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Cheap flights from Chicago O'Hare Intl Airport to Greenville from $93

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Greenville departing on 7/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Chicago O'Hare Intl Airport to Greenville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:05 am - 7:57 am
ORD
-
GSP
22h 52m
1 stop
Multiple Airlines Logo
8:28 pm - 12:42 am
GSP
-
ORD
29h 14m
2 stops
$211Multiple Airlines
Wed, Aug 12 - Mon, Aug 17
Multiple Airlines Logo
8:05 am - 7:57 am
ORD
-
GSP
22h 52m
1 stop
Multiple Airlines Logo
11:07 am - 12:25 pm
GSP
-
ORD
26h 18m
2 stops
$216Multiple Airlines
Wed, Aug 12 - Tue, Aug 18
Multiple Airlines Logo
7:55 am - 7:57 am
ORD
-
GSP
23h 02m
1 stop
Multiple Airlines Logo
3:18 pm - 12:25 pm
GSP
-
ORD
22h 07m
1 stop
$219Multiple Airlines
Wed, Sep 2 - Mon, Sep 7
Multiple Airlines Logo
5:05 am - 7:54 pm
ORD
-
GSP
13h 49m
1 stop
Multiple Airlines Logo
3:17 pm - 12:24 pm
GSP
-
ORD
22h 07m
1 stop
$225Multiple Airlines
Thu, Jun 4 - Sun, Jun 7
Multiple Airlines Logo
8:05 am - 7:57 am
ORD
-
GSP
22h 52m
1 stop
Multiple Airlines Logo
12:06 pm - 12:25 pm
GSP
-
ORD
25h 19m
1 stop
$234Multiple Airlines
Wed, Aug 12 - Mon, Aug 17
Multiple Airlines Logo
4:59 pm - 7:35 am
ORD
-
GSP
13h 36m
1 stop
Multiple Airlines Logo
3:48 pm - 12:25 pm
GSP
-
ORD
21h 37m
1 stop
$248Multiple Airlines
Sat, Jul 4 - Wed, Jul 8
Multiple Airlines Logo
5:10 am - 8:46 pm
ORD
-
GSP
14h 36m
1 stop
Multiple Airlines Logo
9:43 pm - 12:24 pm
GSP
-
ORD
15h 41m
1 stop
$249Multiple Airlines
Thu, Jun 18 - Mon, Jun 22
Multiple Airlines Logo
7:55 am - 7:57 am
ORD
-
GSP
23h 02m
1 stop
Multiple Airlines Logo
11:07 am - 7:55 pm
GSP
-
ORD
9h 48m
2 stops
$251Multiple Airlines
Wed, Sep 2 - Tue, Sep 8
Multiple Airlines Logo
8:20 am - 4:15 pm
ORD
-
GSP
6h 55m
1 stop
Multiple Airlines Logo
1:22 pm - 12:24 pm
GSP
-
ORD
24h 02m
1 stop
$254Multiple Airlines
Mon, Jun 1 - Mon, Jun 8
American Airlines Logo
4:40 pm - 7:32 pm
ORD
-
GSP
1h 52mnonstop
American Airlines Logo
8:24 pm - 9:30 pm
GSP
-
ORD
2h 06mnonstop
$255American Airlines
Wed, Sep 23 - Tue, Sep 29

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Southwest flights from Chicago O'Hare Intl Airport to Greenville

Our best Southwest deals on Chicago O'Hare Intl Airport to Greenville flight tickets
Southwest
May 26
ORD2:40 pmChicago O'Hare Intl
6h 00m
1 stop
GSP9:40 pmGreenville
May 28
GSP6:25 amGreenville
7h 25m
1 stop
ORD12:50 pmChicago O'Hare Intl
$280
Southwest
May 11
ORD2:40 pmChicago O'Hare Intl
6h 35m
1 stop
GSP10:15 pmGreenville
May 12
GSP6:45 amGreenville
7h 05m
1 stop
ORD12:50 pmChicago O'Hare Intl
$401
Southwest
May 11
ORD2:40 pmChicago O'Hare Intl
6h 35m
1 stop
GSP10:15 pmGreenville
May 14
GSP6:25 amGreenville
7h 25m
1 stop
ORD12:50 pmChicago O'Hare Intl
$429

United Airlines flights from Chicago O'Hare Intl Airport to Greenville

Our best United Airlines deals on Chicago O'Hare Intl Airport to Greenville flight tickets
United Airlines
Jun 17
ORD6:55 amChicago O'Hare Intl
2h 00m
GSP9:55 amGreenville
Jun 23
GSP5:43 pmGreenville
2h 17m
ORD7:00 pmChicago O'Hare Intl
$265
United Airlines
May 22
ORD7:08 amChicago O'Hare Intl
2h 06m
GSP10:14 amGreenville
May 27
GSP7:40 pmGreenville
4h 46m
1 stop
ORD11:26 pmChicago O'Hare Intl
$292
United Airlines
Aug 13
ORD8:40 amChicago O'Hare Intl
4h 39m
1 stop
GSP2:19 pmGreenville
Aug 16
GSP6:30 amGreenville
2h 07m
ORD7:37 amChicago O'Hare Intl
$306

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 8/12

8:05 am-7:57 am

1 stop22h 52m

Greenville

Mon 8/17

8:28 pm-12:42 am

2 stops29h 14m

$211

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 8/12

8:05 am-7:57 am

1 stop22h 52m

Greenville

Tue 8/18

11:07 am-12:25 pm

2 stops26h 18m

$216

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 9/2

7:55 am-7:57 am

1 stop23h 02m

Greenville

Mon 9/7

3:18 pm-12:25 pm

1 stop22h 07m

$219

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 6/4

5:05 am-7:54 pm

1 stop13h 49m

Greenville

Sun 6/7

3:17 pm-12:24 pm

1 stop22h 07m

$225

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 8/12

8:05 am-7:57 am

1 stop22h 52m

Greenville

Mon 8/17

12:06 pm-12:25 pm

1 stop25h 19m

$234

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Sat 7/4

4:59 pm-7:35 am

1 stop13h 36m

Greenville

Wed 7/8

3:48 pm-12:25 pm

1 stop21h 37m

$248

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Thu 6/18

5:10 am-8:46 pm

1 stop14h 36m

Greenville

Mon 6/22

9:43 pm-12:24 pm

1 stop15h 41m

$249

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 9/2

7:55 am-7:57 am

1 stop23h 02m

Greenville

Tue 9/8

11:07 am-7:55 pm

2 stops9h 48m

$251

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Mon 6/1

8:20 am-4:15 pm

1 stop6h 55m

Greenville

Mon 6/8

1:22 pm-12:24 pm

1 stop24h 02m

$254
Quickest round-trip

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

Wed 9/23

4:40 pm-7:32 pm

Nonstop1h 52m

Greenville

Tue 9/29

8:24 pm-9:30 pm

Nonstop2h 06m

$255

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Greenville from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago O'Hare Intl Airport and Greenville?

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from Chicago O'Hare Intl Airport averaging around $283.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Saturday is the cheapest day to fly to Greenville from Chicago O'Hare Intl Airport. The lowest ticket price found for a Saturday departure recently was $269. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $400. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the morning. Flights from Chicago O'Hare Intl Airport to Greenville during this time can be as low as $293. Flights to Greenville are more costly in the evening, with an average ticket price of $331. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

What is the cheapest Chicago O'Hare Intl to Greenville flight route?

Fly from Chicago O'Hare Intl to Greenville for the best Chicago O'Hare Intl - Greenville flight prices

How far in advance should I book a flight from Chicago O'Hare Intl Airport to Greenville?

You are more likely to see cheaper flights to Greenville from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Greenville for around $304 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Greenville from Chicago O'Hare Intl Airport for as low as $194 on momondo.

Can stopping save me money on Chicago O'Hare Intl Airport to Greenville flights?

You could potentially save up to 12% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Greenville flight.

How have Chicago O'Hare Intl Airport to Greenville flight prices changed over time?

As of May 2026, prices for Chicago O'Hare Intl Airport to Greenville flights are approximately 17% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Greenville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Greenville (ORD to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Greenville

Best Price Found

$213

Fastest flight time

1h 53m

Direct flights

Every day

Airports in Greenville

1 airport
The best one-way flight to Greenville from Chicago O'Hare Intl Airport in the past 72 hours is $213. The best round-trip flight deal from Chicago O'Hare Intl Airport to Greenville found on momondo in the last 72 hours is $335.
The fastest flight from Chicago O'Hare Intl Airport to Greenville takes 1h 53m
Direct flights go from Chicago O'Hare Intl Airport to Greenville every day.
There is 1 airport in Greenville. From Chicago O'Hare Intl Airport there are direct flights to Greenville (GSP).
Search flight deals

Frequently asked questions about flying from Chicago O'Hare Intl Airport to Greenville

  • How far is Chicago O'Hare Intl to Greenville by plane?

    Chicago O'Hare Intl and Greenville are 575.0 mi apart from one another. Typically, this will take 1h 53m by plane in normal conditions.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Greenville Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Greenville Airport were last updated today.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Greenville Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Greenville Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Greenville Airport.

  • What documentation or ID do you need to fly to Greenville Airport?

    The necessary travel and health documents for your Greenville Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Greenville?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Greenville?

Best airlines flying from Chicago O'Hare Intl Airport to Greenville

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Greenville with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $146Free CancellationRating
7.9
8,459 reviews
Search Delta flights
American AirlinesPriceFrom $202Free CancellationRating
7.1
11,668 reviews
Search American Airlines flights
United AirlinesPriceFrom $209Free CancellationRating
7.4
9,683 reviews
Search United Airlines flights

  • United Airlines Flights From Chicago O'Hare Intl Airport to Greenville

    United Airlines flight deals from Chicago O'Hare Intl Airport to Greenville start from $209 round-trip. Over the 23 United Airlines flights for this route in a normal week, average airfare is usually $319 round-trip - but some users have found much cheaper deals with momondo.

  • American Airlines Flights From Chicago O'Hare Intl Airport to Greenville

    The best American Airlines deal for Chicago O'Hare Intl Airport to Greenville flight tickets found on momondo in the last 72 hours was $202, round-trip. It should be noted that an average American Airlines flight deal for this route in this time was higher, at $285 round-trip. American Airlines operates 12 flights out of Chicago O'Hare Intl Airport into Greenville in an average week, so prices vary by time and availability. 11,668 American Airlines reviews by users on momondo have scored the airline at 7.1/10.

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Anderson
Simpsonville
Greenwood
Greer
Seneca
Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Greenville with flexible booking policies on momondo?

momondo does allow users to show only those flights to Greenville from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Greenville?

momondo provides multiple filters to help you find the best flight to Greenville from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Greenville right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Greenville flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Greenville trip

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