Cheap flights from North Carolina to Panama City from $138

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from North Carolina to Panama City departing on 5/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from North Carolina to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
3:30 pm - 6:36 pm
TYS
-
ECP
4h 06m
1 stop
Delta Logo
7:41 am - 2:33 pm
ECP
-
TYS
5h 52m
1 stop
$221Delta
Wed, May 13 - Mon, May 18
Southwest Logo
6:35 am - 9:35 am
TYS
-
ECP
4h 00m
1 stop
Southwest Logo
7:00 am - 11:50 am
ECP
-
TYS
3h 50m
1 stop
$233Southwest
Tue, Mar 17 - Wed, Mar 18
Southwest Logo
6:35 am - 9:35 am
TYS
-
ECP
4h 00m
1 stop
Southwest Logo
7:00 am - 5:40 pm
ECP
-
TYS
9h 40m
2 stops
$238Southwest
Tue, Mar 17 - Wed, Mar 18
Southwest Logo
7:50 am - 7:35 pm
TYS
-
ECP
12h 45m
2 stops
Southwest Logo
10:10 am - 8:05 pm
ECP
-
TYS
8h 55m
2 stops
$249Southwest
Tue, Mar 17 - Wed, Mar 18
Delta Logo
3:28 pm - 6:36 pm
AVL
-
ECP
4h 08m
1 stop
Delta Logo
2:47 pm - 9:09 pm
ECP
-
AVL
5h 22m
1 stop
$249Delta
Sat, Jun 6 - Thu, Jun 11
Southwest Logo
3:45 pm - 9:20 pm
TYS
-
ECP
6h 35m
1 stop
Southwest Logo
7:00 am - 11:50 am
ECP
-
TYS
3h 50m
1 stop
$256Southwest
Fri, Mar 27 - Tue, Mar 31
Delta Logo
5:10 pm - 7:27 pm
TYS
-
ECP
3h 17m
1 stop
Delta Logo
6:43 pm - 11:57 pm
ECP
-
TYS
4h 14m
1 stop
$257Delta
Mon, Mar 23 - Mon, Mar 30
American Airlines Logo
8:28 pm - 11:49 pm
TRI
-
ECP
4h 21m
1 stop
American Airlines Logo
4:34 pm - 11:47 pm
ECP
-
TRI
6h 13m
1 stop
$274American Airlines
Sat, Mar 21 - Wed, Mar 25
American Airlines Logo
5:00 am - 10:03 am
ORF
-
ECP
6h 03m
1 stop
American Airlines Logo
7:21 am - 4:20 pm
ECP
-
ORF
7h 59m
2 stops
$303American Airlines
Wed, Apr 15 - Wed, Apr 29
American Airlines Logo
5:18 am - 10:03 am
GSO
-
ECP
5h 45m
1 stop
American Airlines Logo
7:21 am - 1:57 pm
ECP
-
GSO
5h 36m
1 stop
$304American Airlines
Sat, Apr 11 - Mon, Apr 13

United Airlines flights from North Carolina to Panama City, Florida

Our best United Airlines deals on North Carolina to Panama City, Florida flight tickets
United Airlines
Feb 28
GSO8:00 amGreensboro/H. Point
6h 27m
1 stop
ECP1:27 pmPanama City NW Florida Beaches
Mar 7
ECP10:24 amPanama City NW Florida Beaches
6h 17m
1 stop
GSO5:41 pmGreensboro/H. Point
$327
United Airlines
Mar 24
GSO6:15 amGreensboro/H. Point
7h 59m
1 stop
ECP1:14 pmPanama City NW Florida Beaches
Mar 31
ECP2:19 pmPanama City NW Florida Beaches
5h 43m
1 stop
GSO9:02 pmGreensboro/H. Point
$374
United Airlines
Mar 24
RDU8:22 amRaleigh-Durham
5h 52m
1 stop
ECP1:14 pmPanama City NW Florida Beaches
Mar 31
ECP10:19 amPanama City NW Florida Beaches
12h 25m
2 stops
RDU11:44 pmRaleigh-Durham
$378

Delta flights from North Carolina to Panama City, Florida

Our best Delta deals on North Carolina to Panama City, Florida flight tickets
Delta
May 13
TYS3:30 pmKnoxville McGhee Tyson
4h 06m
1 stop
ECP6:36 pmPanama City NW Florida Beaches
May 18
ECP7:41 amPanama City NW Florida Beaches
5h 52m
1 stop
TYS2:33 pmKnoxville McGhee Tyson
$221
Delta
Jun 6
AVL3:28 pmAsheville Regional
4h 08m
1 stop
ECP6:36 pmPanama City NW Florida Beaches
Jun 11
ECP2:47 pmPanama City NW Florida Beaches
5h 22m
1 stop
AVL9:09 pmAsheville Regional
$249
Delta
Mar 23
TYS5:10 pmKnoxville McGhee Tyson
3h 17m
1 stop
ECP7:27 pmPanama City NW Florida Beaches
Mar 30
ECP6:43 pmPanama City NW Florida Beaches
4h 14m
1 stop
TYS11:57 pmKnoxville McGhee Tyson
$257

momondo Fare Finder

 
Customize your flight search to find flights from North Carolina to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 24, 2026.
Use the filters below to find and compare flights from North Carolina to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Wed 5/13

3:30 pm-6:36 pm

1 stop4h 06m

Panama City NW Florida Beaches

Mon 5/18

7:41 am-2:33 pm

1 stop5h 52m

$221

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Tue 3/17

6:35 am-9:35 am

1 stop4h 00m

Panama City NW Florida Beaches

Wed 3/18

7:00 am-11:50 am

1 stop3h 50m

$233

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Tue 3/17

6:35 am-9:35 am

1 stop4h 00m

Panama City NW Florida Beaches

Wed 3/18

7:00 am-5:40 pm

2 stops9h 40m

$238

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Tue 3/17

7:50 am-7:35 pm

2 stops12h 45m

Panama City NW Florida Beaches

Wed 3/18

10:10 am-8:05 pm

2 stops8h 55m

$249

AshevillePanama City

AVL - ECP

AVLECP

Asheville Regional

Sat 6/6

3:28 pm-6:36 pm

1 stop4h 08m

Panama City NW Florida Beaches

Thu 6/11

2:47 pm-9:09 pm

1 stop5h 22m

$249

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Fri 3/27

3:45 pm-9:20 pm

1 stop6h 35m

Panama City NW Florida Beaches

Tue 3/31

7:00 am-11:50 am

1 stop3h 50m

$256

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Mon 3/23

5:10 pm-7:27 pm

1 stop3h 17m

Panama City NW Florida Beaches

Mon 3/30

6:43 pm-11:57 pm

1 stop4h 14m

$257

BlountvillePanama City

TRI - ECP

TRIECP

Blountville Tri Cities TN/VA

Sat 3/21

8:28 pm-11:49 pm

1 stop4h 21m

Panama City NW Florida Beaches

Wed 3/25

4:34 pm-11:47 pm

1 stop6h 13m

$274

NorfolkPanama City

ORF - ECP

ORFECP

Norfolk

Wed 4/15

5:00 am-10:03 am

1 stop6h 03m

Panama City NW Florida Beaches

Wed 4/29

7:21 am-4:20 pm

2 stops7h 59m

$303

GreensboroPanama City

GSO - ECP

GSOECP

Greensboro/H. Point

Sat 4/11

5:18 am-10:03 am

1 stop5h 45m

Panama City NW Florida Beaches

Mon 4/13

7:21 am-1:57 pm

1 stop5h 36m

$304

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Panama City from

How to get the cheapest flight ticket from North Carolina to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City, Florida?

The cheapest month to fly to Panama City, Florida from North Carolina is in August. Flight prices, which tend to average around $232, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Panama City, Florida, with average flight prices from North Carolina averaging around $294.

What is the cheapest North Carolina to Panama City NW Florida Beaches flight route?

Fly from Charlotte Douglas to Panama City NW Florida Beaches for the best North Carolina - Panama City NW Florida Beaches flight prices

How far in advance should I book a flight to Panama City, Florida?

You are more likely to see cheaper flights to Panama City, Florida from North Carolina when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City, Florida for around $372 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City, Florida from North Carolina for as low as $275 on momondo.

What cabin class options are available on North Carolina to Panama City NW Florida Beaches flights?

There are 3 cabin classes available to choose from on North Carolina to Panama City NW Florida Beaches flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on North Carolina to Panama City, Florida flights?

You could potentially save up to 56% on your flight if you consider stops on a North Carolina to Panama City, Florida flight.

Cheap North Carolina to Panama City, Florida flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from North Carolina to Panama City, Florida

Best Price Found

$383

Fastest flight time

1h 49m

Direct flights

Every day

Airports in Panama City, Florida

1 airport
The best flight deal from North Carolina to Panama City, Florida found on momondo in the last 72 hours is $383
The fastest flight from North Carolina to Panama City, Florida takes 1h 49m
Direct flights go from North Carolina to Panama City, Florida every day.
There is 1 airport in Panama City, Florida. From North Carolina there are direct flights to Panama City NW Florida Beaches (ECP).
  • When did momondo last update prices for flights from North Carolina to Panama City NW Florida Beaches Airport?

    Prices for flights from North Carolina to Panama City NW Florida Beaches Airport refresh daily.

  • How many operators does momondo search for flights from North Carolina to Panama City NW Florida Beaches Airport?

  • How old do you have to be to fly from North Carolina to Panama City NW Florida Beaches Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from North Carolina to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents required for your trip to Panama City NW Florida Beaches Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Panama City NW Florida Beaches Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from North Carolina to Panama City, Florida?

Best airlines flying from North Carolina to Panama City, Florida

Compare and see reviews for airlines that fly from North Carolina to Panama City, Florida with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $158Free CancellationRating
7.9
8,239 reviews
Search Delta flights
American AirlinesPriceFrom $232Free CancellationRating
7.2
11,344 reviews
Search American Airlines flights
SouthwestPriceFrom $276Free CancellationRating
8.0
4,300 reviews
Search Southwest flights

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from North Carolina to Panama City?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Panama City from North Carolina.

Can I find flights from North Carolina to Panama City with flexible booking policies on momondo?

Flights from North Carolina to Panama City with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from North Carolina to Panama City?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama City from North Carolina.

I’m not ready to book a flight from North Carolina to Panama City right now. Can momondo alert me if prices change?

If you are not ready to book a flight from North Carolina to Panama City now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Panama City and let you know when they change.

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1 adult
Thu 3/26
Thu 4/2

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