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Cheap flights from New Orleans to Knoxville from $114

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from New Orleans to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:03 pm - 5:53 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
22h 50m1 stop Tampa
Multiple Airlines Logo
9:00 am - 4:10 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
32h 10m2 stops Orlando Sanford Intl Atlanta Hartsfield-Jackson
$263Multiple Airlines
Fri, Oct 2 - Tue, Oct 13
Multiple Airlines Logo
1:58 pm - 8:39 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 41m1 stop Orlando
Multiple Airlines Logo
5:38 pm - 7:07 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
26h 29m1 stop Orlando Sanford Intl
$268Multiple Airlines
Mon, Sep 21 - Thu, Sep 24
American Airlines Logo
3:46 pm - 11:22 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
6h 36m1 stop Dallas/Fort Worth
American Airlines Logo
6:15 am - 11:43 amTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
6h 28m1 stop Charlotte Douglas
$287American Airlines
Sat, Sep 26 - Tue, Sep 29
American Airlines Logo
5:49 am - 1:53 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
7h 04m1 stop Dallas/Fort Worth
American Airlines Logo
5:35 pm - 10:58 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
6h 23m1 stop Dallas/Fort Worth
$287American Airlines
Fri, Sep 11 - Tue, Sep 15
United Airlines Logo
8:00 am - 2:42 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 42m1 stop Washington, D.C. Dulles Intl
United Airlines Logo
12:00 pm - 5:55 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
6h 55m1 stop Houston George Bush Intcntl
$287United Airlines
Tue, Jan 26 - Sat, Jan 30
United Airlines Logo
7:00 am - 1:20 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 20m1 stop Houston George Bush Intcntl
United Airlines Logo
7:00 am - 1:09 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
7h 09m1 stop Chicago O'Hare Intl
$287United Airlines
Sun, Sep 6 - Thu, Sep 10
Southwest Logo
6:10 am - 1:15 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
6h 05m2 stops Houston Hobby Dallas Love Field
Southwest Logo
3:00 pm - 9:55 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
7h 55m1 stop Denver Intl
$298Southwest
Sat, Sep 26 - Tue, Sep 29
Delta Logo
5:15 am - 11:18 amMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
5h 03m1 stop Atlanta Hartsfield-Jackson
Delta Logo
7:25 pm - 10:13 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
3h 48m1 stop Atlanta Hartsfield-Jackson
$301Delta
Wed, Sep 23 - Mon, Sep 28
Delta Logo
6:21 am - 10:44 amMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
3h 23m1 stop Atlanta Hartsfield-Jackson
Delta Logo
5:40 am - 8:00 amTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
3h 20m1 stop Atlanta Hartsfield-Jackson
$301Delta
Sat, Sep 19 - Mon, Sep 21
Southwest Logo
9:20 am - 7:00 pmMSY  New Orleans Louis Armstrong-TYS Knoxville McGhee Tyson
8h 40m2 stops Houston Hobby Nashville Intl
Southwest Logo
4:20 pm - 8:55 pmTYS  Knoxville McGhee Tyson-MSY New Orleans Louis Armstrong
5h 35m1 stop Dallas Love Field
$341Southwest
Wed, Sep 30 - Sat, Oct 3

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American Airlines flights from New Orleans to Knoxville

Our best American Airlines deals on New Orleans to Knoxville flight tickets
American Airlines
Sep 11
MSY5:49 amNew Orleans Louis Armstrong
7h 04m
1 stop
TYS1:53 pmKnoxville McGhee Tyson
Sep 15
TYS5:35 pmKnoxville McGhee Tyson
6h 23m
1 stop
MSY10:58 pmNew Orleans Louis Armstrong
$287
American Airlines
Nov 18
MSY7:44 amNew Orleans Louis Armstrong
7h 58m
1 stop
TYS4:42 pmKnoxville McGhee Tyson
Nov 22
TYS5:30 amKnoxville McGhee Tyson
5h 39m
1 stop
MSY10:09 amNew Orleans Louis Armstrong
$327
American Airlines
Dec 11
MSY10:53 amNew Orleans Louis Armstrong
7h 07m
1 stop
TYS7:00 pmKnoxville McGhee Tyson
Dec 13
TYS8:04 pmKnoxville McGhee Tyson
5h 04m
1 stop
MSY12:08 amNew Orleans Louis Armstrong
$340

United Airlines flights from New Orleans to Knoxville

Our best United Airlines deals on New Orleans to Knoxville flight tickets
United Airlines
Sep 6
MSY7:00 amNew Orleans Louis Armstrong
5h 20m
1 stop
TYS1:20 pmKnoxville McGhee Tyson
Sep 10
TYS7:00 amKnoxville McGhee Tyson
7h 09m
1 stop
MSY1:09 pmNew Orleans Louis Armstrong
$287
United Airlines
Oct 10
MSY2:21 pmNew Orleans Louis Armstrong
5h 28m
1 stop
TYS8:49 pmKnoxville McGhee Tyson
Oct 17
TYS6:00 amKnoxville McGhee Tyson
8h 15m
1 stop
MSY1:15 pmNew Orleans Louis Armstrong
$338
United Airlines
Sep 12
MSY12:03 pmNew Orleans Louis Armstrong
5h 12m
1 stop
TYS6:15 pmKnoxville McGhee Tyson
Sep 16
TYS6:00 pmKnoxville McGhee Tyson
5h 18m
1 stop
MSY10:18 pmNew Orleans Louis Armstrong
$367

momondo Fare Finder

 
Use the filters below to find and compare flights from New Orleans to Knoxville that are best for you.

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Route

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Price

Cheapest round-trip

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Fri 10/2

6:03 pm-5:53 pm

1 stop22h 50m

Knoxville McGhee Tyson

Tue 10/13

9:00 am-4:10 pm

2 stops32h 10m

$263

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Mon 9/21

1:58 pm-8:39 pm

1 stop5h 41m

Knoxville McGhee Tyson

Thu 9/24

5:38 pm-7:07 pm

1 stop26h 29m

$268

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Sat 9/26

3:46 pm-11:22 pm

1 stop6h 36m

Knoxville McGhee Tyson

Tue 9/29

6:15 am-11:43 am

1 stop6h 28m

$287

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Fri 9/11

5:49 am-1:53 pm

1 stop7h 04m

Knoxville McGhee Tyson

Tue 9/15

5:35 pm-10:58 pm

1 stop6h 23m

$287

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Tue 1/26

8:00 am-2:42 pm

1 stop5h 42m

Knoxville McGhee Tyson

Sat 1/30

12:00 pm-5:55 pm

1 stop6h 55m

$287

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Sun 9/6

7:00 am-1:20 pm

1 stop5h 20m

Knoxville McGhee Tyson

Thu 9/10

7:00 am-1:09 pm

1 stop7h 09m

$287

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Sat 9/26

6:10 am-1:15 pm

2 stops6h 05m

Knoxville McGhee Tyson

Tue 9/29

3:00 pm-9:55 pm

1 stop7h 55m

$298

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Wed 9/23

5:15 am-11:18 am

1 stop5h 03m

Knoxville McGhee Tyson

Mon 9/28

7:25 pm-10:13 pm

1 stop3h 48m

$301
Quickest round-trip

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Sat 9/19

6:21 am-10:44 am

1 stop3h 23m

Knoxville McGhee Tyson

Mon 9/21

5:40 am-8:00 am

1 stop3h 20m

$301

New OrleansKnoxville

MSY New Orleans Louis Armstrong - TYS Knoxville McGhee Tyson

MSYTYS

New Orleans Louis Armstrong

Wed 9/30

9:20 am-7:00 pm

2 stops8h 40m

Knoxville McGhee Tyson

Sat 10/3

4:20 pm-8:55 pm

1 stop5h 35m

$341

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from New Orleans to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between New Orleans and Knoxville?

Prices are currently low for flights on this route.

Typical prices usually range from $346 to $444.
The lowest price recently found on this route was $263.

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from New Orleans, with most prices found around $376. If you aren’t able to travel during the month of February, then book flights to Knoxville from New Orleans during April instead. Flights to Knoxville in April, while not as cheap as those in February, still average around $388.

How far in advance should I book a flight from New Orleans to Knoxville?

You are more likely to see cheaper flights to Knoxville from New Orleans when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $464 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from New Orleans for as low as $313 on momondo.

How have New Orleans to Knoxville flight prices changed over time?

As of August 2026, prices for New Orleans to Knoxville flights are approximately 12% more expensive when compared to flights at the same time last year.

When to book flights from New Orleans to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from New Orleans to Knoxville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap New Orleans to Knoxville (MSY to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from New Orleans to Knoxville

Best Price Found

$114

Fastest flight time

2h 00m

Direct flights

Sat

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from New Orleans in the past 72 hours is $114. The best round-trip flight deal from New Orleans to Knoxville found on momondo in the last 72 hours is $263.
The fastest flight from New Orleans to Knoxville takes 2h 00m
Direct flights go from New Orleans to Knoxville on Saturday. There are no airlines offering direct flights.
There is 1 airport in Knoxville. From New Orleans there are direct flights to Knoxville McGhee Tyson (TYS).
Search flight deals

Frequently asked questions about flying from New Orleans to Knoxville

  • How far is New Orleans Louis Armstrong to Knoxville McGhee Tyson by plane?

    The straight-line distance from New Orleans Louis Armstrong to Knoxville McGhee Tyson is 546.5 mi. By plane, this route typically takes 2h 00m.

  • When did momondo last update prices for flights from New Orleans Louis Armstrong Airport to Knoxville McGhee Tyson Airport?

    Prices for flights from New Orleans Louis Armstrong Airport to Knoxville McGhee Tyson Airport were last updated today.

  • How many operators does momondo search for flights from New Orleans Louis Armstrong Airport to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from New Orleans Louis Armstrong Airport to Knoxville McGhee Tyson Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from New Orleans Louis Armstrong Airport to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from New Orleans to Knoxville?

Best airlines flying from New Orleans to Knoxville

Compare and see reviews for airlines that fly from New Orleans to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $259Free CancellationRating
7.1
11,981 reviews
Search American Airlines flights
DeltaPriceFrom $276Free CancellationRating
7.8
8,514 reviews
Search Delta flights
SouthwestPriceFrom $318Free CancellationRating
8.0
4,213 reviews
Search Southwest flights
United AirlinesPriceFrom $336Free CancellationRating
7.4
10,113 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Alcoa
Corbin
Maryville
Crossville
Murphy
Oak Ridge
Kodak
Newport
Dandridge
Lenoir City
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from New Orleans to Knoxville?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from New Orleans to Knoxville. momondo saves you time and could save you money on your trip.

Can I find flights from New Orleans to Knoxville with flexible booking policies on momondo?

Flights from New Orleans to Knoxville with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from New Orleans to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from New Orleans.

I’m not ready to book a flight from New Orleans to Knoxville right now. Can momondo alert me if prices change?

If you are not ready to book a flight from New Orleans to Knoxville now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Knoxville and let you know when they change.

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