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Cheap flights from Myrtle Beach to Chicago from $68

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Chicago departing on 4/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
10:20 am - 4:14 pm
MYR
-
ORD
6h 54m
1 stop
Spirit Airlines Logo
2:09 pm - 8:44 am
ORD
-
MYR
17h 35m
1 stop
$156Spirit Airlines
Sat, Apr 18 - Tue, Apr 21
Multiple Airlines Logo
10:20 am - 4:14 pm
MYR
-
ORD
6h 54m
1 stop
Multiple Airlines Logo
1:27 pm - 11:29 pm
ORD
-
MYR
9h 02m
1 stop
$160Multiple Airlines
Sat, Apr 18 - Sat, Apr 25
Spirit Airlines Logo
10:20 am - 4:14 pm
MYR
-
ORD
6h 54m
1 stop
Spirit Airlines Logo
2:09 pm - 8:44 am
ORD
-
MYR
17h 35m
1 stop
$164Spirit Airlines
Sat, Apr 18 - Tue, Apr 21
Spirit Airlines Logo
10:20 am - 4:14 pm
MYR
-
ORD
6h 54m
1 stop
Spirit Airlines Logo
2:09 pm - 2:44 pm
ORD
-
MYR
23h 35m
1 stop
$170Spirit Airlines
Sat, Apr 25 - Mon, Apr 27
Spirit Airlines Logo
10:20 am - 7:57 pm
MYR
-
ORD
10h 37m
1 stop
Spirit Airlines Logo
12:53 pm - 8:44 am
ORD
-
MYR
18h 51m
1 stop
$171Spirit Airlines
Wed, Apr 15 - Sat, Apr 18
Multiple Airlines Logo
10:20 am - 7:57 pm
MYR
-
ORD
10h 37m
1 stop
Multiple Airlines Logo
1:27 pm - 11:29 pm
ORD
-
MYR
9h 02m
1 stop
$176Multiple Airlines
Wed, Apr 15 - Fri, Apr 17
Spirit Airlines Logo
6:28 pm - 5:15 pm
MYR
-
ORD
23h 47m
1 stop
Spirit Airlines Logo
7:15 pm - 11:29 pm
ORD
-
MYR
27h 14m
1 stop
$178Spirit Airlines
Mon, Apr 13 - Wed, Apr 15
Spirit Airlines Logo
8:31 pm - 4:14 pm
MYR
-
ORD
20h 43m
1 stop
Spirit Airlines Logo
2:09 pm - 8:44 am
ORD
-
MYR
17h 35m
1 stop
$180Spirit Airlines
Fri, May 1 - Mon, May 4
Spirit Airlines Logo
10:20 am - 4:14 pm
MYR
-
ORD
6h 54m
1 stop
Spirit Airlines Logo
10:33 am - 11:29 pm
ORD
-
MYR
11h 56m
2 stops
$187Spirit Airlines
Sat, Apr 18 - Sat, Apr 25
Southwest Logo
5:20 pm - 10:50 pm
MYR
-
MDW
6h 30m
1 stop
Southwest Logo
5:15 pm - 8:10 pm
MDW
-
MYR
1h 55mnonstop
$261Southwest
Wed, Apr 1 - Sat, Apr 4

Spirit Airlines flights from Myrtle Beach to Chicago

Our best Spirit Airlines deals on Myrtle Beach to Chicago flight tickets
Spirit Airlines
Apr 18
MYR10:20 amMyrtle Beach Intl
6h 54m
1 stop
ORD4:14 pmChicago O'Hare Intl
Apr 21
ORD2:09 pmChicago O'Hare Intl
17h 35m
1 stop
MYR8:44 amMyrtle Beach Intl
$156
Spirit Airlines
Apr 18
MYR10:20 amMyrtle Beach Intl
6h 54m
1 stop
ORD4:14 pmChicago O'Hare Intl
Apr 21
ORD2:09 pmChicago O'Hare Intl
17h 35m
1 stop
MYR8:44 amMyrtle Beach Intl
$164
Spirit Airlines
Apr 15
MYR10:20 amMyrtle Beach Intl
10h 37m
1 stop
ORD7:57 pmChicago O'Hare Intl
Apr 18
ORD12:53 pmChicago O'Hare Intl
18h 51m
1 stop
MYR8:44 amMyrtle Beach Intl
$171

American Airlines flights from Myrtle Beach to Chicago

Our best American Airlines deals on Myrtle Beach to Chicago flight tickets
American Airlines
Apr 1
MYR5:10 amMyrtle Beach Intl
6h 40m
1 stop
ORD10:50 amChicago O'Hare Intl
Apr 4
ORD8:00 amChicago O'Hare Intl
2h 11m
MYR11:11 amMyrtle Beach Intl
$261
American Airlines
Mar 13
MYR12:16 pmMyrtle Beach Intl
2h 39m
ORD1:55 pmChicago O'Hare Intl
Mar 14
ORD6:08 amChicago O'Hare Intl
4h 40m
1 stop
MYR11:48 amMyrtle Beach Intl
$382
American Airlines
Mar 9
MYR5:19 pmMyrtle Beach Intl
7h 17m
1 stop
ORD11:36 pmChicago O'Hare Intl
Mar 16
ORD8:35 amChicago O'Hare Intl
2h 11m
MYR11:46 amMyrtle Beach Intl
$409

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 6, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sat 4/18

10:20 am-4:14 pm

1 stop6h 54m

Chicago O'Hare Intl

Tue 4/21

2:09 pm-8:44 am

1 stop17h 35m

$156

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sat 4/18

10:20 am-4:14 pm

1 stop6h 54m

Chicago O'Hare Intl

Sat 4/25

1:27 pm-11:29 pm

1 stop9h 02m

$160

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sat 4/18

10:20 am-4:14 pm

1 stop6h 54m

Chicago O'Hare Intl

Tue 4/21

2:09 pm-8:44 am

1 stop17h 35m

$164

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sat 4/25

10:20 am-4:14 pm

1 stop6h 54m

Chicago O'Hare Intl

Mon 4/27

2:09 pm-2:44 pm

1 stop23h 35m

$170

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 4/15

10:20 am-7:57 pm

1 stop10h 37m

Chicago O'Hare Intl

Sat 4/18

12:53 pm-8:44 am

1 stop18h 51m

$171

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 4/15

10:20 am-7:57 pm

1 stop10h 37m

Chicago O'Hare Intl

Fri 4/17

1:27 pm-11:29 pm

1 stop9h 02m

$176

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Mon 4/13

6:28 pm-5:15 pm

1 stop23h 47m

Chicago O'Hare Intl

Wed 4/15

7:15 pm-11:29 pm

1 stop27h 14m

$178

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 5/1

8:31 pm-4:14 pm

1 stop20h 43m

Chicago O'Hare Intl

Mon 5/4

2:09 pm-8:44 am

1 stop17h 35m

$180

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sat 4/18

10:20 am-4:14 pm

1 stop6h 54m

Chicago O'Hare Intl

Sat 4/25

10:33 am-11:29 pm

2 stops11h 56m

$187
Quickest round-trip

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 4/1

5:20 pm-10:50 pm

1 stop6h 30m

Chicago Midway

Sat 4/4

5:15 pm-8:10 pm

Nonstop1h 55m

$261

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Myrtle Beach to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Chicago?

What is the cheapest month to fly to Chicago?

The month of August is, on average, the cheapest month to fly to Chicago from Myrtle Beach, with most prices found around $245. If you’re not able to fly to Chicago in August, then May is your next best option. Flight prices from Myrtle Beach to Chicago during May average around $251.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $325. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Chicago for around $566.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is at noon. Flights from Myrtle Beach to Chicago during this time can be as low as $387. In contrast, the most expensive time of day to depart to Chicago is in the afternoon when prices are around $426.

What is the cheapest Myrtle Beach Intl to Chicago flight route?

Fly from Myrtle Beach Intl to Chicago O'Hare Intl for the best Myrtle Beach Intl - Chicago flight prices

What cabin class options are available on Myrtle Beach Intl to Chicago flights?

There are 4 cabin classes available to choose from on Myrtle Beach Intl to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Chicago flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Chicago.

How have Myrtle Beach to Chicago flight prices changed over time?

As of March 2026, prices for Myrtle Beach to Chicago flights are approximately 7% cheaper when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Chicago (MYR to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Chicago

Best Price Found

$151

Fastest flight time

2h 05m

Direct flights

Every day

Airports in Chicago

3 airports
The best one-way flight to Chicago from Myrtle Beach in the past 72 hours is $151. The best round-trip flight deal from Myrtle Beach to Chicago found on momondo in the last 72 hours is $303.
The fastest flight from Myrtle Beach to Chicago takes 2h 05m
Direct flights go from Myrtle Beach to Chicago every day.
There are 3 airports in Chicago. From Myrtle Beach there are direct flights to Chicago O'Hare Intl (ORD), Chicago Midway (MDW).
Search flight deals

  • How far is Myrtle Beach Intl to Chicago by plane?

    There are 738.8 mi between Myrtle Beach Intl and Chicago. By plane, this route typically takes 2h 05m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Chicago?

    Prices for flights from Myrtle Beach Intl Airport to Chicago refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Chicago?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Chicago?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Chicago?

  • What is the most popular airline from Myrtle Beach to Chicago?

Best airlines flying from Myrtle Beach to Chicago

Compare and see reviews for airlines that fly from Myrtle Beach to Chicago with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $65Free CancellationRating
6.3
8,498 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $178Free CancellationRating
7.4
9,403 reviews
Search United Airlines flights
American AirlinesPriceFrom $191Free CancellationRating
7.1
11,397 reviews
Search American Airlines flights
SouthwestPriceFrom $239Free CancellationRating
8.0
4,310 reviews
Search Southwest flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Portage
Lansing
Valparaiso
Schererville
Munster
Crown Point
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Chicago?

It is quick and easy to find Myrtle Beach to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Myrtle Beach to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago
Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport