Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Myrtle Beach to Chicago from $64

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Chicago departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Myrtle Beach to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
10:09 am - 12:40 am
MYR
-
ORD
15h 31m
1 stop
Spirit Airlines Logo
8:16 pm - 8:13 am
ORD
-
MYR
10h 57m
1 stop
$142Spirit Airlines
Wed, Mar 4 - Thu, Mar 5
Spirit Airlines Logo
9:54 pm - 9:22 am
MYR
-
ORD
12h 28m
1 stop
Spirit Airlines Logo
6:51 pm - 2:55 pm
ORD
-
MYR
19h 04m
1 stop
$147Spirit Airlines
Fri, Feb 27 - Mon, Mar 2
Spirit Airlines Logo
9:09 am - 7:11 pm
MYR
-
ORD
11h 02m
1 stop
Spirit Airlines Logo
8:16 pm - 8:13 am
ORD
-
MYR
10h 57m
1 stop
$150Spirit Airlines
Thu, Mar 5 - Mon, Mar 9
Spirit Airlines Logo
9:09 am - 9:13 pm
MYR
-
ORD
13h 04m
1 stop
Spirit Airlines Logo
6:51 pm - 8:58 am
ORD
-
MYR
13h 07m
1 stop
$158Spirit Airlines
Fri, Feb 20 - Mon, Feb 23
Spirit Airlines Logo
9:09 am - 12:40 am
MYR
-
ORD
16h 31m
2 stops
Spirit Airlines Logo
8:16 pm - 8:13 am
ORD
-
MYR
10h 57m
1 stop
$162Spirit Airlines
Wed, Mar 4 - Thu, Mar 5
Spirit Airlines Logo
6:28 pm - 5:15 pm
MYR
-
ORD
23h 47m
1 stop
Spirit Airlines Logo
6:10 pm - 5:33 pm
ORD
-
MYR
22h 23m
1 stop
$164Spirit Airlines
Sun, Mar 15 - Wed, Mar 18
Spirit Airlines Logo
9:49 pm - 10:20 am
MYR
-
ORD
13h 31m
1 stop
Spirit Airlines Logo
6:10 pm - 5:33 pm
ORD
-
MYR
22h 23m
1 stop
$166Spirit Airlines
Sat, Mar 14 - Wed, Mar 18
Spirit Airlines Logo
9:54 pm - 9:22 am
MYR
-
ORD
12h 28m
1 stop
Spirit Airlines Logo
6:51 pm - 11:02 am
ORD
-
MYR
15h 11m
1 stop
$167Spirit Airlines
Sun, Feb 22 - Fri, Mar 6
Multiple Airlines Logo
9:58 pm - 1:00 pm
MYR
-
MDW
16h 02m
1 stop
Multiple Airlines Logo
7:30 am - 8:58 am
MDW
-
MYR
24h 28m
1 stop
$172Multiple Airlines
Fri, Apr 17 - Mon, Apr 20
Delta Logo
6:00 am - 9:56 am
MYR
-
MDW
4h 56m
1 stop
Delta Logo
6:00 am - 12:57 pm
MDW
-
MYR
5h 57m
1 stop
$277Delta
Wed, Apr 29 - Wed, May 6

Spirit Airlines flights from Myrtle Beach to Chicago

Our best Spirit Airlines deals on Myrtle Beach to Chicago flight tickets
Spirit Airlines
Mar 4
MYR10:09 amMyrtle Beach Intl
15h 31m
1 stop
ORD12:40 amChicago O'Hare Intl
Mar 5
ORD8:16 pmChicago O'Hare Intl
10h 57m
1 stop
MYR8:13 amMyrtle Beach Intl
$142
Spirit Airlines
Feb 27
MYR9:54 pmMyrtle Beach Intl
12h 28m
1 stop
ORD9:22 amChicago O'Hare Intl
Mar 2
ORD6:51 pmChicago O'Hare Intl
19h 04m
1 stop
MYR2:55 pmMyrtle Beach Intl
$147
Spirit Airlines
Mar 5
MYR9:09 amMyrtle Beach Intl
11h 02m
1 stop
ORD7:11 pmChicago O'Hare Intl
Mar 9
ORD8:16 pmChicago O'Hare Intl
10h 57m
1 stop
MYR8:13 amMyrtle Beach Intl
$150

Southwest flights from Myrtle Beach to Chicago

Our best Southwest deals on Myrtle Beach to Chicago flight tickets
Southwest
Mar 14
MYR7:15 pmMyrtle Beach Intl
2h 15m
MDW8:30 pmChicago Midway
Mar 18
MDW7:45 amChicago Midway
6h 20m
1 stop
MYR3:05 pmMyrtle Beach Intl
$369
Southwest
Feb 16
MYR6:30 pmMyrtle Beach Intl
2h 20m
MDW7:50 pmChicago Midway
Feb 20
MDW4:15 pmChicago Midway
1h 55m
MYR7:10 pmMyrtle Beach Intl
$377
Southwest
Mar 14
MYR2:15 pmMyrtle Beach Intl
6h 55m
1 stop
MDW8:10 pmChicago Midway
Mar 18
MDW7:45 amChicago Midway
6h 20m
1 stop
MYR3:05 pmMyrtle Beach Intl
$378

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 3/4

10:09 am-12:40 am

1 stop15h 31m

Chicago O'Hare Intl

Thu 3/5

8:16 pm-8:13 am

1 stop10h 57m

$142

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 2/27

9:54 pm-9:22 am

1 stop12h 28m

Chicago O'Hare Intl

Mon 3/2

6:51 pm-2:55 pm

1 stop19h 04m

$147

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 3/5

9:09 am-7:11 pm

1 stop11h 02m

Chicago O'Hare Intl

Mon 3/9

8:16 pm-8:13 am

1 stop10h 57m

$150

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 2/20

9:09 am-9:13 pm

1 stop13h 04m

Chicago O'Hare Intl

Mon 2/23

6:51 pm-8:58 am

1 stop13h 07m

$158

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 3/4

9:09 am-12:40 am

2 stops16h 31m

Chicago O'Hare Intl

Thu 3/5

8:16 pm-8:13 am

1 stop10h 57m

$162

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sun 3/15

6:28 pm-5:15 pm

1 stop23h 47m

Chicago O'Hare Intl

Wed 3/18

6:10 pm-5:33 pm

1 stop22h 23m

$164

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sat 3/14

9:49 pm-10:20 am

1 stop13h 31m

Chicago O'Hare Intl

Wed 3/18

6:10 pm-5:33 pm

1 stop22h 23m

$166

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sun 2/22

9:54 pm-9:22 am

1 stop12h 28m

Chicago O'Hare Intl

Fri 3/6

6:51 pm-11:02 am

1 stop15h 11m

$167

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Fri 4/17

9:58 pm-1:00 pm

1 stop16h 02m

Chicago Midway

Mon 4/20

7:30 am-8:58 am

1 stop24h 28m

$172

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 4/29

6:00 am-9:56 am

1 stop4h 56m

Chicago Midway

Wed 5/6

6:00 am-12:57 pm

1 stop5h 57m

$277

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Chicago from

How to get the cheapest flight ticket from Myrtle Beach to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

The month of August is, on average, the cheapest month to fly to Chicago from Myrtle Beach, with most prices found around $245. If you’re not able to fly to Chicago in August, then May is your next best option. Flight prices from Myrtle Beach to Chicago during May average around $251.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $320. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Chicago for around $532.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is at noon. Flights from Myrtle Beach to Chicago during this time can be as low as $377. In contrast, the most expensive time of day to depart to Chicago is in the afternoon when prices are around $431.

What is the cheapest Myrtle Beach Intl to Chicago flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best Myrtle Beach Intl - Chicago flight prices

What cabin class options are available on Myrtle Beach Intl to Chicago flights?

There are 4 cabin classes available to choose from on Myrtle Beach Intl to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Chicago flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Chicago.

How have Myrtle Beach to Chicago flight prices changed over time?

As of February 2026, prices for Myrtle Beach to Chicago flights are approximately 202% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Chicago (MYR to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Chicago

Best Price Found

$168

Fastest flight time

2h 05m

Direct flights

Every day

Airports in Chicago

3 airports
The best one-way flight to Chicago from Myrtle Beach in the past 72 hours is $168. The best round-trip flight deal from Myrtle Beach to Chicago found on momondo in the last 72 hours is $289.
The fastest flight from Myrtle Beach to Chicago takes 2h 05m
Direct flights go from Myrtle Beach to Chicago every day.
There are 3 airports in Chicago. From Myrtle Beach there are direct flights to Chicago O'Hare Intl (ORD), Chicago Midway (MDW).
Search flight deals

  • How far is Myrtle Beach Intl to Chicago by plane?

    There are 738.8 mi between Myrtle Beach Intl and Chicago. By plane, this route typically takes 2h 05m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Chicago?

    Prices for flights from Myrtle Beach Intl Airport to Chicago refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Chicago?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Chicago?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Chicago?

  • What is the most popular airline from Myrtle Beach to Chicago?

Best airlines flying from Myrtle Beach to Chicago

Compare and see reviews for airlines that fly from Myrtle Beach to Chicago with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $65Free CancellationRating
6.3
8,396 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $167Free CancellationRating
7.2
11,213 reviews
Search American Airlines flights
United AirlinesPriceFrom $178Free CancellationRating
7.4
9,231 reviews
Search United Airlines flights
SouthwestPriceFrom $197Free CancellationRating
8.0
4,272 reviews
Search Southwest flights

  • Southwest Flights From Myrtle Beach to Chicago

    The lowest priced Southwest flight from Myrtle Beach to Chicago from the last 72 hours was $197. Generally, Southwest has 4 flights on this route every week with an average price of $385. Southwest is rated 8.0/10 by our users.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Portage
Lansing
Schererville
Valparaiso
Munster
Crown Point
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Chicago?

It is quick and easy to find Myrtle Beach to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Myrtle Beach to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

An easier way to manage your Chicago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 3/5
Thu 3/12
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago
Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport