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Cheap flights from Myrtle Beach to Chicago from $124

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:22 am - 11:34 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
16h 12m1 stop Fort Lauderdale
Multiple Airlines Logo
3:55 pm - 11:44 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
18h 49m2 stops Atlanta Hartsfield-Jackson Tampa
$250Multiple Airlines
Tue, Nov 24 - Tue, Dec 1
Multiple Airlines Logo
2:23 pm - 4:14 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
26h 51m1 stop Fort Lauderdale
Multiple Airlines Logo
8:25 am - 8:33 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
23h 08m1 stop Fort Lauderdale
$264Multiple Airlines
Wed, Jan 20 - Tue, Feb 16
Multiple Airlines Logo
2:23 pm - 4:14 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
26h 51m1 stop Fort Lauderdale
Multiple Airlines Logo
8:25 am - 2:08 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
28h 43m1 stop Fort Lauderdale
$265Multiple Airlines
Wed, Jan 20 - Wed, Feb 17
Southwest Logo
7:05 pm - 10:45 pmMYR  Myrtle Beach Intl-MDW Chicago Midway
4h 40m1 stop Nashville Intl
Southwest Logo
12:50 pm - 6:25 pmMDW  Chicago Midway-MYR Myrtle Beach Intl
4h 35m1 stop Baltimore/Washington
$311Southwest
Tue, Nov 17 - Wed, Nov 18
American Airlines Logo
8:44 pm - 11:59 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
4h 15m1 stop Charlotte Douglas
American Airlines Logo
5:19 am - 12:12 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
5h 53m1 stop Charlotte Douglas
$311American Airlines
Tue, Nov 24 - Tue, Dec 1
American Airlines Logo
11:52 am - 4:38 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
5h 46m1 stop Washington, D.C. Reagan-National
American Airlines Logo
5:23 am - 1:24 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
7h 01m1 stop Charlotte Douglas
$311American Airlines
Thu, Dec 3 - Mon, Dec 7
Southwest Logo
10:45 am - 5:50 pmMYR  Myrtle Beach Intl-MDW Chicago Midway
8h 05m2 stops Nashville Intl Lambert-St Louis
Southwest Logo
12:50 pm - 6:25 pmMDW  Chicago Midway-MYR Myrtle Beach Intl
4h 35m1 stop Baltimore/Washington
$316Southwest
Tue, Nov 17 - Wed, Nov 18
Southwest Logo
7:05 pm - 10:45 pmMYR  Myrtle Beach Intl-MDW Chicago Midway
4h 40m1 stop Nashville Intl
Southwest Logo
6:30 am - 1:00 pmMDW  Chicago Midway-MYR Myrtle Beach Intl
5h 30m2 stops Lambert-St Louis Nashville Intl
$316Southwest
Wed, Dec 16 - Thu, Dec 17
United Airlines Logo
5:54 pm - 12:01 amMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
7h 07m1 stop Newark
United Airlines Logo
10:39 am - 5:11 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
5h 32m1 stop Newark
$399United Airlines
Fri, Nov 13 - Tue, Nov 17
United Airlines Logo
11:27 am - 4:24 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
5h 57m1 stop Newark
United Airlines Logo
9:00 am - 5:11 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
7h 11m1 stop Newark
$399United Airlines
Sat, Nov 14 - Wed, Nov 18

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Delta flights from Myrtle Beach to Chicago

Our best Delta deals on Myrtle Beach to Chicago flight tickets
Delta
Dec 1
MYR6:59 pmMyrtle Beach Intl
5h 57m
1 stop
ORD11:56 pmChicago O'Hare Intl
Dec 8
ORD6:49 amChicago O'Hare Intl
5h 44m
1 stop
MYR1:33 pmMyrtle Beach Intl
$357
Delta
Dec 6
MYR6:57 pmMyrtle Beach Intl
5h 59m
1 stop
ORD11:56 pmChicago O'Hare Intl
Dec 8
ORD10:36 amChicago O'Hare Intl
6h 27m
1 stop
MYR6:03 pmMyrtle Beach Intl
$358
Delta
Feb 11
MYR6:00 amMyrtle Beach Intl
4h 52m
1 stop
MDW9:52 amChicago Midway
Feb 17
MDW6:00 amChicago Midway
6h 35m
1 stop
MYR1:35 pmMyrtle Beach Intl
$359

United Airlines flights from Myrtle Beach to Chicago

Our best United Airlines deals on Myrtle Beach to Chicago flight tickets
United Airlines
Nov 13
MYR5:54 pmMyrtle Beach Intl
7h 07m
1 stop
ORD12:01 amChicago O'Hare Intl
Nov 17
ORD10:39 amChicago O'Hare Intl
5h 32m
1 stop
MYR5:11 pmMyrtle Beach Intl
$399
United Airlines
Nov 13
MYR5:54 pmMyrtle Beach Intl
7h 07m
1 stop
ORD12:01 amChicago O'Hare Intl
Nov 15
ORD9:20 pmChicago O'Hare Intl
12h 01m
2 stops
MYR10:21 amMyrtle Beach Intl
$758

momondo Fare Finder

 
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Tue 11/24

8:22 am-11:34 pm

1 stop16h 12m

Chicago O'Hare Intl

Tue 12/1

3:55 pm-11:44 am

2 stops18h 49m

$250

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Wed 1/20

2:23 pm-4:14 pm

1 stop26h 51m

Chicago O'Hare Intl

Tue 2/16

8:25 am-8:33 am

1 stop23h 08m

$264

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Wed 1/20

2:23 pm-4:14 pm

1 stop26h 51m

Chicago O'Hare Intl

Wed 2/17

8:25 am-2:08 pm

1 stop28h 43m

$265
Quickest round-trip

Myrtle BeachChicago

MYR Myrtle Beach Intl - MDW Chicago Midway

MYRMDW

Myrtle Beach Intl

Tue 11/17

7:05 pm-10:45 pm

1 stop4h 40m

Chicago Midway

Wed 11/18

12:50 pm-6:25 pm

1 stop4h 35m

$311

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Tue 11/24

8:44 pm-11:59 pm

1 stop4h 15m

Chicago O'Hare Intl

Tue 12/1

5:19 am-12:12 pm

1 stop5h 53m

$311

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Thu 12/3

11:52 am-4:38 pm

1 stop5h 46m

Chicago O'Hare Intl

Mon 12/7

5:23 am-1:24 pm

1 stop7h 01m

$311

Myrtle BeachChicago

MYR Myrtle Beach Intl - MDW Chicago Midway

MYRMDW

Myrtle Beach Intl

Tue 11/17

10:45 am-5:50 pm

2 stops8h 05m

Chicago Midway

Wed 11/18

12:50 pm-6:25 pm

1 stop4h 35m

$316

Myrtle BeachChicago

MYR Myrtle Beach Intl - MDW Chicago Midway

MYRMDW

Myrtle Beach Intl

Wed 12/16

7:05 pm-10:45 pm

1 stop4h 40m

Chicago Midway

Thu 12/17

6:30 am-1:00 pm

2 stops5h 30m

$316

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Fri 11/13

5:54 pm-12:01 am

1 stop7h 07m

Chicago O'Hare Intl

Tue 11/17

10:39 am-5:11 pm

1 stop5h 32m

$399

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Sat 11/14

11:27 am-4:24 pm

1 stop5h 57m

Chicago O'Hare Intl

Wed 11/18

9:00 am-5:11 pm

1 stop7h 11m

$399

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Myrtle Beach to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Chicago?

Prices are currently low for flights on this route.

Typical prices usually range from $376 to $429.
The lowest price recently found on this route was $250.

What is the cheapest month to fly to Chicago?

The month of January is, on average, the cheapest month to fly to Chicago from Myrtle Beach, with most prices found around $293. If you’re not able to fly to Chicago in January, then December is your next best option. Flight prices from Myrtle Beach to Chicago during December average around $343.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Wednesday when prices can be found for as low as $420. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Chicago for around $528.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is at noon. Flights from Myrtle Beach to Chicago during this time can be as low as $410. In contrast, the most expensive time of day to depart to Chicago is in the evening when prices are around $492.

What is the cheapest Myrtle Beach Intl to Chicago flight route?

Fly from Myrtle Beach Intl to Chicago O'Hare Intl for the best Myrtle Beach Intl - Chicago flight prices

What cabin class options are available on Myrtle Beach to Chicago flights?

There are 4 cabin classes available to choose from on Myrtle Beach to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Chicago flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Chicago.

How have Myrtle Beach to Chicago flight prices changed over time?

As of October 2026, prices for Myrtle Beach to Chicago flights are approximately 415% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Chicago (MYR to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Chicago

Best Price Found

$124

Fastest flight time

2h 15m

Direct flights

Mon, Tue, Wed, Thu, Fri and Sun

Airports in Chicago

3 airports
The best one-way flight to Chicago from Myrtle Beach in the past 72 hours is $124. The best round-trip flight deal from Myrtle Beach to Chicago found on momondo in the last 72 hours is $250.
The fastest flight from Myrtle Beach to Chicago takes 2h 15m
Direct flights go from Myrtle Beach to Chicago on Monday, Tuesday, Wednesday, Thursday, Friday and Sunday. There are no airlines offering direct flights.
There are 3 airports in Chicago. From Myrtle Beach there are direct flights to Chicago O'Hare Intl (ORD), Chicago Midway (MDW).
Search flight deals

Frequently asked questions about flying from Myrtle Beach to Chicago

  • How far is Myrtle Beach Intl to Chicago by plane?

    There are 738.8 mi between Myrtle Beach Intl and Chicago. By plane, this route typically takes 2h 15m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Chicago?

    Prices for flights from Myrtle Beach Intl Airport to Chicago refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Chicago?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Chicago?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Chicago?

  • What is the most popular airline from Myrtle Beach to Chicago?

Best airlines flying from Myrtle Beach to Chicago

Compare and see reviews for airlines that fly from Myrtle Beach to Chicago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $238Free CancellationRating
7.3
10,462 reviews
Search United Airlines flights
SouthwestPriceFrom $280Free CancellationRating
7.9
4,225 reviews
Search Southwest flights
American AirlinesPriceFrom $299Free CancellationRating
7.0
12,223 reviews
Search American Airlines flights

  • Southwest Flights From Myrtle Beach to Chicago

    The lowest priced Southwest flight from Myrtle Beach to Chicago from the last 72 hours was $280. Generally, Southwest has 1 flight on this route every week with an average price of $418. Southwest is rated 7.9/10 by our users.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Portage
Lansing
Saint Joseph
Benton Harbor
Valparaiso
Schererville
Munster
Chesterton
Monticello
Crown Point
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Chicago?

It is quick and easy to find Myrtle Beach to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Myrtle Beach to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport