Cheap flights from Myrtle Beach to Chicago from $128

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Myrtle Beach to Chicago

Cheap round-trip flights

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Multiple Airlines Logo
1:53 pm - 4:52 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
27h 59m1 stop Fort Lauderdale
Multiple Airlines Logo
8:59 am - 8:03 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
22h 04m1 stop Fort Lauderdale
$260Multiple Airlines
Mon, Dec 21 - Thu, Dec 31
Multiple Airlines Logo
1:53 pm - 4:52 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
27h 59m1 stop Fort Lauderdale
Multiple Airlines Logo
8:59 am - 8:03 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
22h 04m1 stop Fort Lauderdale
$273Multiple Airlines
Mon, Dec 21 - Thu, Dec 31
Multiple Airlines Logo
1:53 pm - 4:14 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
27h 21m1 stop Fort Lauderdale
Multiple Airlines Logo
5:32 pm - 8:50 amORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
14h 18m2 stops Atlanta Hartsfield-Jackson Orlando
$284Multiple Airlines
Mon, Feb 22 - Sat, Feb 27
American Airlines Logo
8:04 am - 11:10 amMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
4h 06m1 stop Charlotte Douglas
American Airlines Logo
4:29 pm - 7:48 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
2h 19mnonstop
$347American Airlines
Wed, Jan 20 - Wed, Feb 17
Southwest Logo
7:15 pm - 11:15 pmMYR  Myrtle Beach Intl-MDW Chicago Midway
5h 00m1 stop Baltimore/Washington
Southwest Logo
12:45 pm - 7:25 pmMDW  Chicago Midway-MYR Myrtle Beach Intl
5h 40m1 stop Nashville Intl
$357Southwest
Mon, Dec 21 - Thu, Dec 31
Southwest Logo
3:25 pm - 9:30 pmMYR  Myrtle Beach Intl-MDW Chicago Midway
7h 05m1 stop Baltimore/Washington
Southwest Logo
12:50 pm - 6:25 pmMDW  Chicago Midway-MYR Myrtle Beach Intl
4h 35m1 stop Baltimore/Washington
$357Southwest
Tue, Dec 1 - Wed, Dec 2
American Airlines Logo
4:21 pm - 10:32 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
7h 11m1 stop Charlotte Douglas
American Airlines Logo
8:10 am - 1:24 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
4h 14m1 stop Charlotte Douglas
$357American Airlines
Fri, Dec 4 - Mon, Dec 7
American Airlines Logo
11:52 am - 4:38 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
5h 46m1 stop Washington, D.C. Reagan-National
American Airlines Logo
8:10 am - 1:24 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
4h 14m1 stop Charlotte Douglas
$357American Airlines
Fri, Dec 4 - Tue, Dec 15
United Airlines Logo
11:27 am - 6:38 pmMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
8h 11m1 stop Newark
United Airlines Logo
11:25 am - 5:48 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
5h 23m1 stop Newark
$369United Airlines
Fri, Jan 15 - Mon, Jan 18
United Airlines Logo
11:27 am - 7:53 amMYR  Myrtle Beach Intl-ORD Chicago O'Hare Intl
21h 26m2 stops Newark Detroit Metropolitan Wayne County
United Airlines Logo
10:30 am - 5:48 pmORD  Chicago O'Hare Intl-MYR Myrtle Beach Intl
6h 18m1 stop Newark
$394United Airlines
Fri, Jan 8 - Sat, Jan 9

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American Airlines flights from Myrtle Beach to Chicago

Our best American Airlines deals on Myrtle Beach to Chicago flight tickets
American Airlines
Dec 4
MYR11:52 amMyrtle Beach Intl
5h 46m
1 stop
ORD4:38 pmChicago O'Hare Intl
Dec 15
ORD8:10 amChicago O'Hare Intl
4h 14m
1 stop
MYR1:24 pmMyrtle Beach Intl
$357
American Airlines
Feb 22
MYR10:09 amMyrtle Beach Intl
7h 11m
1 stop
ORD4:20 pmChicago O'Hare Intl
Feb 27
ORD9:46 amChicago O'Hare Intl
2h 18m
MYR1:04 pmMyrtle Beach Intl
$384
American Airlines
Dec 4
MYR11:52 amMyrtle Beach Intl
5h 46m
1 stop
ORD4:38 pmChicago O'Hare Intl
Dec 11
ORD9:00 amChicago O'Hare Intl
5h 51m
1 stop
MYR3:51 pmMyrtle Beach Intl
$429

Delta flights from Myrtle Beach to Chicago

Our best Delta deals on Myrtle Beach to Chicago flight tickets
Delta
Dec 8
MYR6:59 pmMyrtle Beach Intl
5h 57m
1 stop
ORD11:56 pmChicago O'Hare Intl
Dec 13
ORD6:49 amChicago O'Hare Intl
5h 44m
1 stop
MYR1:33 pmMyrtle Beach Intl
$363
Delta
Dec 4
MYR6:59 pmMyrtle Beach Intl
5h 57m
1 stop
ORD11:56 pmChicago O'Hare Intl
Dec 15
ORD3:59 pmChicago O'Hare Intl
5h 48m
1 stop
MYR10:47 pmMyrtle Beach Intl
$369
Delta
Dec 19
MYR7:03 pmMyrtle Beach Intl
5h 59m
1 stop
ORD12:02 amChicago O'Hare Intl
Dec 22
ORD5:25 amChicago O'Hare Intl
6h 49m
1 stop
MYR1:14 pmMyrtle Beach Intl
$374

momondo Fare Finder

 
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Mon 12/21

1:53 pm-4:52 pm

1 stop27h 59m

Chicago O'Hare Intl

Thu 12/31

8:59 am-8:03 am

1 stop22h 04m

$260

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Mon 12/21

1:53 pm-4:52 pm

1 stop27h 59m

Chicago O'Hare Intl

Thu 12/31

8:59 am-8:03 am

1 stop22h 04m

$273

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Mon 2/22

1:53 pm-4:14 pm

1 stop27h 21m

Chicago O'Hare Intl

Sat 2/27

5:32 pm-8:50 am

2 stops14h 18m

$284
Quickest round-trip

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Wed 1/20

8:04 am-11:10 am

1 stop4h 06m

Chicago O'Hare Intl

Wed 2/17

4:29 pm-7:48 pm

Nonstop2h 19m

$347

Myrtle BeachChicago

MYR Myrtle Beach Intl - MDW Chicago Midway

MYRMDW

Myrtle Beach Intl

Mon 12/21

7:15 pm-11:15 pm

1 stop5h 00m

Chicago Midway

Thu 12/31

12:45 pm-7:25 pm

1 stop5h 40m

$357

Myrtle BeachChicago

MYR Myrtle Beach Intl - MDW Chicago Midway

MYRMDW

Myrtle Beach Intl

Tue 12/1

3:25 pm-9:30 pm

1 stop7h 05m

Chicago Midway

Wed 12/2

12:50 pm-6:25 pm

1 stop4h 35m

$357

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Fri 12/4

4:21 pm-10:32 pm

1 stop7h 11m

Chicago O'Hare Intl

Mon 12/7

8:10 am-1:24 pm

1 stop4h 14m

$357

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Fri 12/4

11:52 am-4:38 pm

1 stop5h 46m

Chicago O'Hare Intl

Tue 12/15

8:10 am-1:24 pm

1 stop4h 14m

$357

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Fri 1/15

11:27 am-6:38 pm

1 stop8h 11m

Chicago O'Hare Intl

Mon 1/18

11:25 am-5:48 pm

1 stop5h 23m

$369

Myrtle BeachChicago

MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl

MYRORD

Myrtle Beach Intl

Fri 1/8

11:27 am-7:53 am

2 stops21h 26m

Chicago O'Hare Intl

Sat 1/9

10:30 am-5:48 pm

1 stop6h 18m

$394

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Myrtle Beach to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Myrtle Beach and Chicago?

Prices are currently low for flights on this route.

Typical prices usually range from $376 to $418.
The lowest price recently found on this route was $260.

What is the cheapest month to fly to Chicago?

The month of January is, on average, the cheapest month to fly to Chicago from Myrtle Beach, with most prices found around $293. If you’re not able to fly to Chicago in January, then April is your next best option. Flight prices from Myrtle Beach to Chicago during April average around $344.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Tuesday when prices can be found for as low as $422. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Chicago for around $528.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is at noon. Flights from Myrtle Beach to Chicago during this time can be as low as $410. In contrast, the most expensive time of day to depart to Chicago is in the evening when prices are around $492.

What is the cheapest Myrtle Beach Intl to Chicago flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best Myrtle Beach Intl - Chicago flight prices

What cabin class options are available on Myrtle Beach to Chicago flights?

There are 4 cabin classes available to choose from on Myrtle Beach to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Chicago flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Chicago.

How have Myrtle Beach to Chicago flight prices changed over time?

As of November 2026, prices for Myrtle Beach to Chicago flights are approximately 205% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Chicago (MYR to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Chicago

Best Price Found

$128

Fastest flight time

2h 15m

Direct flights

Mon, Tue, Thu, Fri and Sun

Airports in Chicago

3 airports
The best one-way flight to Chicago from Myrtle Beach in the past 72 hours is $128. The best round-trip flight deal from Myrtle Beach to Chicago found on momondo in the last 72 hours is $260.
The fastest flight from Myrtle Beach to Chicago takes 2h 15m
Direct flights go from Myrtle Beach to Chicago on Monday, Tuesday, Thursday, Friday and Sunday. There are no airlines offering direct flights.
There are 3 airports in Chicago. From Myrtle Beach there are direct flights to Chicago O'Hare Intl (ORD), Chicago Midway (MDW).

Frequently asked questions about flying from Myrtle Beach to Chicago

  • How far is Myrtle Beach Intl to Chicago by plane?

    There are 738.8 mi between Myrtle Beach Intl and Chicago. By plane, this route typically takes 2h 15m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Chicago?

    Prices for flights from Myrtle Beach Intl Airport to Chicago refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Chicago?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Chicago?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Chicago?

  • What is the most popular airline from Myrtle Beach to Chicago?

Best airlines flying from Myrtle Beach to Chicago

Compare and see reviews for airlines that fly from Myrtle Beach to Chicago with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $238Free CancellationRating
7.3
10,476 reviews
Search United Airlines flights
SouthwestPriceFrom $280Free CancellationRating
8.0
4,218 reviews
Search Southwest flights
American AirlinesPriceFrom $299Free CancellationRating
7.0
12,226 reviews
Search American Airlines flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Portage
Lansing
Benton Harbor
Saint Joseph
Valparaiso
Schererville
Munster
Chesterton
Monticello
Crown Point
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Chicago?

It is quick and easy to find Myrtle Beach to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Myrtle Beach to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

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1 adult
Wed 12/9
Wed 12/16

Find better results for your trip to the United States

Fly into one of these airports located in Chicago