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Cheap flights from Myrtle Beach to Chicago from $80

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Chicago departing on 11/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Spirit Airlines Logo
9:22 am - 2:31 pmMYR-ORD
6h 09m1 stop
Spirit Airlines Logo
3:26 pm - 10:26 pmORD-MYR
6h 00m1 stop
$167Spirit Airlines
Find Deal
Thu, Nov 13 - Mon, Nov 17
Spirit Airlines Logo
9:22 am - 2:31 pmMYR-ORD
6h 09m1 stop
Spirit Airlines Logo
10:12 am - 11:54 pmORD-MYR
12h 42m1 stop
$168Spirit Airlines
Find Deal
Tue, Nov 18 - Tue, Nov 25
Spirit Airlines Logo
2:15 pm - 9:48 pmMYR-ORD
8h 33m1 stop
Spirit Airlines Logo
5:00 am - 5:48 pmORD-MYR
11h 48m1 stop
$175Spirit Airlines
Find Deal
Fri, Dec 12 - Tue, Dec 16
Spirit Airlines Logo
9:22 am - 6:34 pmMYR-ORD
10h 12m1 stop
Spirit Airlines Logo
2:01 pm - 7:54 pmORD-MYR
4h 53m1 stop
$176Spirit Airlines
Find Deal
Fri, Nov 14 - Tue, Nov 25
Multiple Airlines Logo
9:54 am - 1:57 pmMYR-ORD
29h 03m1 stop
Multiple Airlines Logo
11:42 am - 10:41 amORD-MYR
21h 59m1 stop
$182Multiple Airlines
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Wed, Dec 10 - Thu, Jan 8
Multiple Airlines Logo
2:15 pm - 10:39 pmMYR-MDW
9h 24m1 stop
Multiple Airlines Logo
10:18 am - 7:35 pmMDW-MYR
8h 17m1 stop
$184Multiple Airlines
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Fri, Dec 12 - Sun, Jan 11
Southwest Logo
2:55 pm - 4:05 pmMYR-MDW
2h 10mnonstop
Southwest Logo
11:25 am - 2:25 pmMDW-MYR
2h 00mnonstop
$315Southwest
Find Deal
Wed, Dec 10 - Tue, Jan 13
Southwest Logo
2:55 pm - 4:05 pmMYR-MDW
2h 10mnonstop
Southwest Logo
1:15 pm - 7:45 pmMDW-MYR
5h 30m1 stop
$325Southwest
Find Deal
Wed, Dec 10 - Tue, Jan 13
Delta Logo
6:00 am - 6:18 pmMYR-MDW
13h 18m2 stops
Delta Logo
11:21 am - 6:02 pmMDW-MYR
5h 41m1 stop
$331Delta
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Wed, Dec 10 - Mon, Jan 12
Delta Logo
10:32 am - 4:18 pmMYR-MDW
6h 46m1 stop
Delta Logo
12:50 pm - 6:01 pmMDW-MYR
4h 11m1 stop
$334Delta
Find Deal
Thu, Dec 4 - Wed, Dec 10

Spirit Airlines flights from Myrtle Beach to Chicago

Our best Spirit Airlines deals on Myrtle Beach to Chicago flight tickets
Spirit Airlines
Nov 13
MYR9:22 amMyrtle Beach Intl
6h 09m
1 stop
ORD2:31 pmChicago O'Hare Intl
Nov 17
ORD3:26 pmChicago O'Hare Intl
6h 00m
1 stop
MYR10:26 pmMyrtle Beach Intl
$167
Find similar
Spirit Airlines
Nov 18
MYR9:22 amMyrtle Beach Intl
6h 09m
1 stop
ORD2:31 pmChicago O'Hare Intl
Nov 25
ORD10:12 amChicago O'Hare Intl
12h 42m
1 stop
MYR11:54 pmMyrtle Beach Intl
$168
Find similar
Spirit Airlines
Dec 12
MYR2:15 pmMyrtle Beach Intl
8h 33m
1 stop
ORD9:48 pmChicago O'Hare Intl
Dec 16
ORD5:00 amChicago O'Hare Intl
11h 48m
1 stop
MYR5:48 pmMyrtle Beach Intl
$175
Find similar

Southwest flights from Myrtle Beach to Chicago

Our best Southwest deals on Myrtle Beach to Chicago flight tickets
Southwest
Dec 10
MYR2:55 pmMyrtle Beach Intl
2h 10m
MDW4:05 pmChicago Midway
Jan 13
MDW11:25 amChicago Midway
2h 00m
MYR2:25 pmMyrtle Beach Intl
$315
Find similar
Southwest
Dec 10
MYR2:55 pmMyrtle Beach Intl
2h 10m
MDW4:05 pmChicago Midway
Jan 13
MDW1:15 pmChicago Midway
5h 30m
1 stop
MYR7:45 pmMyrtle Beach Intl
$325
Find similar
Southwest
Dec 30
MYR6:15 pmMyrtle Beach Intl
2h 20m
MDW7:35 pmChicago Midway
Dec 31
MDW2:30 pmChicago Midway
1h 55m
MYR5:25 pmMyrtle Beach Intl
$328
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 11/13

9:22 am-2:31 pm

1 stop6h 09m

Chicago O'Hare Intl

Mon 11/17

3:26 pm-10:26 pm

1 stop6h 00m

$167

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Tue 11/18

9:22 am-2:31 pm

1 stop6h 09m

Chicago O'Hare Intl

Tue 11/25

10:12 am-11:54 pm

1 stop12h 42m

$168

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 12/12

2:15 pm-9:48 pm

1 stop8h 33m

Chicago O'Hare Intl

Tue 12/16

5:00 am-5:48 pm

1 stop11h 48m

$175

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 11/14

9:22 am-6:34 pm

1 stop10h 12m

Chicago O'Hare Intl

Tue 11/25

2:01 pm-7:54 pm

1 stop4h 53m

$176

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 12/10

9:54 am-1:57 pm

1 stop29h 03m

Chicago O'Hare Intl

Thu 1/8

11:42 am-10:41 am

1 stop21h 59m

$182

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Fri 12/12

2:15 pm-10:39 pm

1 stop9h 24m

Chicago Midway

Sun 1/11

10:18 am-7:35 pm

1 stop8h 17m

$184

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 12/10

2:55 pm-4:05 pm

Nonstop2h 10m

Chicago Midway

Tue 1/13

11:25 am-2:25 pm

Nonstop2h 00m

$315

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 12/10

2:55 pm-4:05 pm

Nonstop2h 10m

Chicago Midway

Tue 1/13

1:15 pm-7:45 pm

1 stop5h 30m

$325

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 12/10

6:00 am-6:18 pm

2 stops13h 18m

Chicago Midway

Mon 1/12

11:21 am-6:02 pm

1 stop5h 41m

$331

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Thu 12/4

10:32 am-4:18 pm

1 stop6h 46m

Chicago Midway

Wed 12/10

12:50 pm-6:01 pm

1 stop4h 11m

$334

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Myrtle Beach to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

The month of August is, on average, the cheapest month to fly to Chicago from Myrtle Beach, with most prices found around $245. If you’re not able to fly to Chicago in August, then May is your next best option. Flight prices from Myrtle Beach to Chicago during May average around $251.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $343. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Chicago for around $497.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is in the morning. Flights from Myrtle Beach to Chicago during this time can be as low as $427. In contrast, the most expensive time of day to depart to Chicago is at noon when prices are around $453.

What is the cheapest Myrtle Beach Intl to Chicago flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best Myrtle Beach Intl - Chicago flight prices

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from Myrtle Beach when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $339 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Myrtle Beach for as low as $167 on momondo.

What cabin class options are available on Myrtle Beach Intl to Chicago flights?

There are 4 cabin classes available to choose from on Myrtle Beach Intl to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Myrtle Beach to Chicago flight prices changed over time?

As of October 2025, prices for Myrtle Beach to Chicago flights are approximately 43% more expensive when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Chicago (MYR to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Chicago

Best Price Found

$178

Fastest flight time

2h 10m

Direct flights

Every day

Airports in Chicago

2 airports
The best one-way flight to Chicago from Myrtle Beach in the past 72 hours is $178. The best round-trip flight deal from Myrtle Beach to Chicago found on momondo in the last 72 hours is $393.
The fastest flight from Myrtle Beach to Chicago takes 2h 10m
Direct flights go from Myrtle Beach to Chicago every day.
There are 2 airports near Chicago: Chicago O'Hare Intl (ORD), Chicago Midway (MDW)
Search flight deals

  • How far is Myrtle Beach Intl to Chicago by plane?

    There are 738.8 mi between Myrtle Beach Intl and Chicago. By plane, this route typically takes 2h 10m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Chicago?

    Prices for flights from Myrtle Beach Intl Airport to Chicago refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Chicago?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Chicago?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Chicago?

  • What is the most popular airline from Myrtle Beach to Chicago?

Best airlines flying from Myrtle Beach to Chicago

Compare and see reviews for airlines that fly from Myrtle Beach to Chicago with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $93Free CancellationRating
6.3
8,115 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $167Free CancellationRating
7.2
11,030 reviews
Search American Airlines flights
United AirlinesPriceFrom $193Free CancellationRating
7.4
8,998 reviews
Search United Airlines flights
SouthwestPriceFrom $239Free CancellationRating
8.0
4,242 reviews
Search Southwest flights

  • Southwest Flights From Myrtle Beach to Chicago

    The lowest priced Southwest flight from Myrtle Beach to Chicago from the last 72 hours was $239. Generally, Southwest has 1 flight on this route every week with an average price of $389. Southwest is rated 8.0/10 by our users.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Portage
Lansing
Schererville
Valparaiso
Crown Point
Munster
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Chicago?

It is quick and easy to find Myrtle Beach to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Myrtle Beach to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago
Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport