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Cheap flights from Myrtle Beach to Chicago from $66

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Myrtle Beach to Chicago departing on 10/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Frontier Logo
3:49 pm - 11:03 pmMYR-MDW
8h 14m1 stop
Frontier Logo
8:25 am - 3:04 pmMDW-MYR
5h 39m1 stop
$144Frontier
Find Deal
vie., oct. 24 - dom., oct. 26
United Airlines Logo
4:33 pm - 6:10 pmMYR-ORD
2h 37mnonstop
United Airlines Logo
11:20 am - 2:42 pmORD-MYR
2h 22mnonstop
$147United Airlines
Find Deal
vie., oct. 17 - mar., oct. 21
Southwest Logo
8:25 am - 11:50 amMYR-ORD
4h 25m1 stop
Southwest Logo
1:30 pm - 7:20 pmORD-MYR
4h 50m1 stop
$151Southwest
Find Deal
mié., oct. 8 - sáb., oct. 25
Southwest Logo
8:25 am - 5:55 pmMYR-ORD
10h 30m2 stops
Southwest Logo
12:40 pm - 6:45 pmORD-MYR
5h 05m1 stop
$156Southwest
Find Deal
mié., oct. 8 - sáb., oct. 25
United Airlines Logo
4:33 pm - 6:10 pmMYR-ORD
2h 37mnonstop
United Airlines Logo
10:40 am - 4:56 pmORD-MYR
5h 16m1 stop
$157United Airlines
Find Deal
vie., oct. 17 - mar., oct. 21
American Airlines Logo
7:35 pm - 10:54 pmMYR-ORD
4h 19m1 stop
American Airlines Logo
6:07 am - 11:56 amORD-MYR
4h 49m1 stop
$159American Airlines
Find Deal
mar., oct. 14 - mar., oct. 21
Spirit Airlines Logo
9:11 am - 4:51 pmMYR-ORD
8h 40m1 stop
Spirit Airlines Logo
11:55 am - 8:04 pmORD-MYR
7h 09m1 stop
$167Spirit Airlines
Find Deal
mié., oct. 1 - sáb., oct. 11
Spirit Airlines Logo
9:11 am - 4:51 pmMYR-ORD
8h 40m1 stop
Spirit Airlines Logo
11:57 am - 8:06 pmORD-MYR
7h 09m1 stop
$169Spirit Airlines
Find Deal
mar., sep. 30 - sáb., oct. 4
Multiple Airlines Logo
9:11 am - 4:51 pmMYR-ORD
8h 40m1 stop
Multiple Airlines Logo
2:45 pm - 11:36 amORD-MYR
19h 51m2 stops
$214Multiple Airlines
Find Deal
mié., oct. 1 - sáb., oct. 11
Multiple Airlines Logo
9:11 am - 4:51 pmMYR-ORD
8h 40m1 stop
Multiple Airlines Logo
2:41 pm - 3:04 pmORD-MYR
47h 23m2 stops
$217Multiple Airlines
Find Deal
mié., oct. 1 - vie., oct. 10

Spirit Airlines flights from Myrtle Beach to Chicago

Our best Spirit Airlines deals on Myrtle Beach to Chicago flight tickets
Spirit Airlines
Oct 1
MYR9:11 amMyrtle Beach Intl
8h 40m
1 stop
ORD4:51 pmChicago O'Hare Intl
Oct 11
ORD11:55 amChicago O'Hare Intl
7h 09m
1 stop
MYR8:04 pmMyrtle Beach Intl
$167
Find similar
Spirit Airlines
Sep 30
MYR9:11 amMyrtle Beach Intl
8h 40m
1 stop
ORD4:51 pmChicago O'Hare Intl
Oct 4
ORD11:57 amChicago O'Hare Intl
7h 09m
1 stop
MYR8:06 pmMyrtle Beach Intl
$169
Find similar
Spirit Airlines
Oct 30
MYR8:14 amMyrtle Beach Intl
7h 31m
1 stop
ORD2:45 pmChicago O'Hare Intl
Nov 2
ORD5:00 amChicago O'Hare Intl
11h 58m
1 stop
MYR5:58 pmMyrtle Beach Intl
$174
Find similar

United Airlines flights from Myrtle Beach to Chicago

Our best United Airlines deals on Myrtle Beach to Chicago flight tickets
United Airlines
Oct 17
MYR4:33 pmMyrtle Beach Intl
2h 37m
ORD6:10 pmChicago O'Hare Intl
Oct 21
ORD11:20 amChicago O'Hare Intl
2h 22m
MYR2:42 pmMyrtle Beach Intl
$147
Find similar
United Airlines
Oct 17
MYR4:33 pmMyrtle Beach Intl
2h 37m
ORD6:10 pmChicago O'Hare Intl
Oct 21
ORD10:40 amChicago O'Hare Intl
5h 16m
1 stop
MYR4:56 pmMyrtle Beach Intl
$157
Find similar
United Airlines
Oct 8
MYR5:57 pmMyrtle Beach Intl
6h 33m
1 stop
ORD11:30 pmChicago O'Hare Intl
Oct 25
ORD11:20 amChicago O'Hare Intl
2h 11m
MYR2:31 pmMyrtle Beach Intl
$224
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

vie. 10/24

3:49 pm-11:03 pm

1 stop8h 14m

Chicago Midway

dom. 10/26

8:25 am-3:04 pm

1 stop5h 39m

$144

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

vie. 10/17

4:33 pm-6:10 pm

Nonstop2h 37m

Chicago O'Hare Intl

mar. 10/21

11:20 am-2:42 pm

Nonstop2h 22m

$147

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

mié. 10/8

8:25 am-11:50 am

1 stop4h 25m

Chicago O'Hare Intl

sáb. 10/25

1:30 pm-7:20 pm

1 stop4h 50m

$151

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

mié. 10/8

8:25 am-5:55 pm

2 stops10h 30m

Chicago O'Hare Intl

sáb. 10/25

12:40 pm-6:45 pm

1 stop5h 05m

$156

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

vie. 10/17

4:33 pm-6:10 pm

Nonstop2h 37m

Chicago O'Hare Intl

mar. 10/21

10:40 am-4:56 pm

1 stop5h 16m

$157

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

mar. 10/14

7:35 pm-10:54 pm

1 stop4h 19m

Chicago O'Hare Intl

mar. 10/21

6:07 am-11:56 am

1 stop4h 49m

$159

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

mié. 10/1

9:11 am-4:51 pm

1 stop8h 40m

Chicago O'Hare Intl

sáb. 10/11

11:55 am-8:04 pm

1 stop7h 09m

$167

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

mar. 9/30

9:11 am-4:51 pm

1 stop8h 40m

Chicago O'Hare Intl

sáb. 10/4

11:57 am-8:06 pm

1 stop7h 09m

$169

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

mié. 10/1

9:11 am-4:51 pm

1 stop8h 40m

Chicago O'Hare Intl

sáb. 10/11

2:45 pm-11:36 am

2 stops19h 51m

$214

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

mié. 10/1

9:11 am-4:51 pm

1 stop8h 40m

Chicago O'Hare Intl

vie. 10/10

2:41 pm-3:04 pm

2 stops47h 23m

$217

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Myrtle Beach to Chicago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago?

The month of May is, on average, the cheapest month to fly to Chicago from Myrtle Beach, with most prices found around $243. If you’re not able to fly to Chicago in May, then August is your next best option. Flight prices from Myrtle Beach to Chicago during August average around $245.

What is the cheapest day to depart on your flight to Chicago?

The cheapest day to depart on your flight to Chicago is on a Friday when prices can be found for as low as $346. This is often the case because there is less demand to fly during this day of the week. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Myrtle Beach to Chicago for around $481.

What is the cheapest time of day to depart on your flight to Chicago?

Our most recent data shows that the best time of day to fly to Chicago is at noon. Flights from Myrtle Beach to Chicago during this time can be as low as $382. In contrast, the most expensive time of day to depart to Chicago is in the morning when prices are around $437.

What is the cheapest Myrtle Beach Intl to Chicago flight route?

Fly from Myrtle Beach Intl to Chicago Midway for the best Myrtle Beach Intl - Chicago flight prices

How far in advance should I book a flight to Chicago?

You are more likely to see cheaper flights to Chicago from Myrtle Beach when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago for around $318 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago from Myrtle Beach for as low as $172 on momondo.

What cabin class options are available on Myrtle Beach Intl to Chicago flights?

There are 4 cabin classes available to choose from on Myrtle Beach Intl to Chicago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Myrtle Beach to Chicago flights?

No. A direct flight is the cheapest option for a flight between Myrtle Beach to Chicago.

How have Myrtle Beach to Chicago flight prices changed over time?

As of September 2025, prices for Myrtle Beach to Chicago flights are approximately 58% cheaper when compared to flights at the same time last year.

When to book flights from Myrtle Beach to Chicago

Are you open to changing your travel dates? Check out the ideal times to fly from Myrtle Beach to Chicago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Myrtle Beach to Chicago (MYR to CHI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Myrtle Beach to Chicago

Best Price Found

$127

Fastest flight time

2h 05m

Direct flights

Every day

Airports in Chicago

2 airports
The best one-way flight to Chicago from Myrtle Beach in the past 72 hours is $127. The best round-trip flight deal from Myrtle Beach to Chicago found on momondo in the last 72 hours is $350.
The fastest flight from Myrtle Beach to Chicago takes 2h 05m
Direct flights go from Myrtle Beach to Chicago every day.
There are 2 airports near Chicago: Chicago O'Hare Intl (ORD), Chicago Midway (MDW)
Search flight deals

  • How far is Myrtle Beach Intl to Chicago by plane?

    There are 738.8 mi between Myrtle Beach Intl and Chicago. By plane, this route typically takes 2h 10m.

  • When did momondo last update prices for flights from Myrtle Beach Intl Airport to Chicago?

    Prices for flights from Myrtle Beach Intl Airport to Chicago refresh daily.

  • How many operators does momondo search for flights from Myrtle Beach Intl Airport to Chicago?

  • How old do you have to be to fly from Myrtle Beach Intl Airport to Chicago?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Myrtle Beach Intl Airport to Chicago.

  • What documentation or ID do you need to fly to Chicago?

    The travel and health documents you'll need for your trip to Chicago may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Myrtle Beach to Chicago?

  • What is the most popular airline from Myrtle Beach to Chicago?

Best airlines flying from Myrtle Beach to Chicago

Compare and see reviews for airlines that fly from Myrtle Beach to Chicago with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $46Free CancellationRating
6.3
8,023 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $167Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $193Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
DeltaPriceFrom $196Free CancellationRating
7.9
7,961 reviews
Search Delta flights
SouthwestPriceFrom $239Free CancellationRating
8.0
4,242 reviews
Search Southwest flights

  • Southwest Flights From Myrtle Beach to Chicago

    The lowest priced Southwest flight from Myrtle Beach to Chicago from the last 72 hours was $239. Generally, Southwest has 5 flights on this route every week with an average price of $388. Southwest is rated 8.0/10 by our users.

  • United Airlines Flights From Myrtle Beach to Chicago

    United Airlines (7.4/10 from 8,926 reviews) operates around 7 flights from Myrtle Beach to Chicago in any given week. The average United Airlines airfare for this route is around $360, with deals from around $193 rare but found on momondo. Referenced prices are for round-trip Myrtle Beach to Chicago flight searches in the last 72 hours.

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
New Buffalo
Hammond
Benton Harbor
Saint Joseph
Lansing
Portage
Schererville
Valparaiso
Crown Point
Munster
Chesterton
Monticello
Porter
Griffith
Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Myrtle Beach to Chicago?

It is quick and easy to find Myrtle Beach to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Myrtle Beach to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Myrtle Beach with this policy.

How can momondo help me find flights from Myrtle Beach to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Myrtle Beach. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Myrtle Beach to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Myrtle Beach to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

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vie. 10/17
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Find better results for your trip to the United States

Fly into one of these airports located in Chicago

Airports listed have a maximum distance of 78.5 mi from Chicago
Chicago Midway Airport
Chicago O'Hare Intl Airport
Chicago Greater Rockford Airport