Cheap flights from Missouri to South Carolina from $64
This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to South Carolina departing on 7/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
Discover deals from 900+ travel sites with momondo.
Save money when you book flights with momondo
Big names and deals
Big names and deals
Search 100s of travel sites to compare prices.Filter for what you want
Filter for what you want
Free Wi-Fi? Stopover? Instantly customize your results.Trusted and free
Trusted and free
We’re completely free to use - no hidden charges or fees.Price Alerts
Price Alerts
Not ready to book? to track prices.Find the cheapest flights from Missouri to South Carolina
Cheap round-trip flights
Cheap one-way flights
Cheap last minute flights
Cheap direct flights
Spirit Airlines flights from Missouri to South Carolina
Our best Spirit Airlines deals on Missouri to South Carolina flight tickets
American Airlines flights from Missouri to South Carolina
Our best American Airlines deals on Missouri to South Carolina flight tickets
See travel insights to South Carolina from
How to get the cheapest flight ticket from Missouri to South Carolina
Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip
What is the cheapest month to fly to South Carolina?
The cheapest month to fly to South Carolina from Missouri is in September. Flight prices, which tend to average around $302, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to South Carolina from Missouri during July instead. Flights to South Carolina in July, while not as cheap as those in September, still average around $307.
What is the cheapest day to depart on your flight to South Carolina?
Our data shows that Monday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $353. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $544.
What is the cheapest time of day to depart on your flight to South Carolina?
Our data shows that the cheapest Missouri to South Carolina flights are usually those with departure times in the evening. Our users have found flights to South Carolina in the evening for as low as $387. Try not to purchase tickets in the morning because they tend to be around $425. Of course, these prices can vary depending on the time of year and what airport you fly to.
What is the cheapest Missouri to South Carolina flight route?
Fly from Lambert-St Louis to Myrtle Beach Intl for the best Missouri - South Carolina flight prices
How far in advance should I book a flight to South Carolina?
You are more likely to see cheaper flights to South Carolina from Missouri when booking 12 weeks ahead of your departure date. In general, you can expect to find flights to South Carolina for around $379 when searching 12 weeks out.However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South Carolina from Missouri for as low as $312 on momondo.
What cabin class options are available on Missouri to South Carolina flights?
There are 1 cabin classes available to choose from on Missouri to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.
What is the cheapest airline that flies from Missouri to South Carolina?
Spirit Airlines, American Airlines, and Southwest are the most popular carriers operating from Missouri to South Carolina
What airlines fly to South Carolina?
American Airlines, Delta and Southwest are the top three most popular airlines that fly to South Carolina from Missouri according to our data. American Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to South Carolina. Keep in mind that there are 5 different airlines that fly to South Carolina on a routine basis, so you have a few additional options to choose from.
How many flights depart from Missouri to South Carolina on average per day?
As of June 2025, there are 13 flights per day flying from Missouri to South Carolina. The most common time of day flights depart is 11:00AM, with 63% of flights taking off at noon.
How many flights depart from Missouri to South Carolina on average per week?
As of June 2025, there are 92 flights per week flying from Missouri to South Carolina. The most common day of the week flights depart is Mon, with 17% of flights taking off on this day.
Cheap Missouri to South Carolina flight deals and tips
Find info about flight duration, direct flights, and airports for your flight from Missouri to South Carolina
Best Price Found | $64 |
|---|---|
Fastest flight time | 1h 45m |
Direct flights | Every day |
Airports in South Carolina | 4 airports |
When did momondo last update prices for flights from Missouri to South Carolina?
Prices for flights from Missouri to South Carolina refresh daily.
How many operators does momondo search for flights from Missouri to South Carolina?
As of June 2025, there are 6 operators available to choose from for flights from Missouri to South Carolina.
How old do you have to be to fly from Missouri to South Carolina?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to South Carolina.
What documentation or ID do you need to fly to South Carolina?
The required travel and health documents for your South Carolina trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South Carolina. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Missouri to South Carolina?
momondo data reveals that the most frequently booked plane model on the route from Missouri to South Carolina is Boeing 737-800 Passenger/BBJ2 (winglets), representing 54.05% of all bookings. The subsequent popular models are Boeing 737-700 Passenger/BBJ1 (winglets) at 22.97%, Boeing 737 MAX 8 at 21.62%, and Airbus A220-300 at 1.35%.
Best airlines flying from Missouri to South Carolina
Compare and see reviews for airlines that fly from Missouri to South Carolina with momondo
| Airline | Rating | Free Cancellation | Price | ||
|---|---|---|---|---|---|
| PriceFrom $112 | Free Cancellation | Rating 6.3 8,064 reviews | |||
| PriceFrom $158 | Free Cancellation | Rating 7.2 10,000 reviews | |||
| PriceFrom $196 | Free Cancellation | Rating 8.0 7,963 reviews | |||
| PriceFrom $223 | Free Cancellation | Rating 7.4 8,809 reviews | |||
| PriceFrom $276 | Free Cancellation | Rating 8.0 4,278 reviews |
Why use momondo?
Why should I use momondo to find a flight deal from Missouri to South Carolina?
Finding the right flight to South Carolina from Missouri is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South Carolina quick and easy, saving you time and money.
Can I find flights from Missouri to South Carolina with flexible booking policies on momondo?
Yes. momondo enables you to select and highlight flights to South Carolina from Missouri with this policy.
How can momondo help me find flights from Missouri to South Carolina?
Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Missouri.
I’m not ready to book a flight from Missouri to South Carolina right now. Can momondo alert me if prices change?
Of course. momondo tracks the price of Missouri to South Carolina flights. All you need is a valid email address and we will do the rest; it is that quick and easy.