How many flights depart from Missouri to Des Moines on average per week?

As of November 2025, 14 flights take off from Missouri and land in Des Moines each week. The most common flight departure day for this route is Mon, with 29% of weekly flights taking off on this day.

How long does it take to fly to Des Moines?

If you’re flying from a popular airport in Missouri, such as St. Louis or Kansas City, and flying into Des Moines, then you can expect flight times to average 1h 10m and 9h 17m, respectively.

What is the cheapest airline that flies from Missouri to Des Moines?

Southwest, Frontier, and Delta are the most popular carriers operating from Missouri to Des Moines

How many flights depart from Missouri to Des Moines on average per day?

2 flights are operational daily from Missouri to Des Moines as of November 2025. The most popular departure time for this route is 9:00AM, with 37% of flights per day taking off at noon.

When did momondo last update prices for flights from Missouri to Des Moines Airport?

Prices for flights from Missouri to Des Moines Airport were last updated today.

How many operators does momondo search for flights from Missouri to Des Moines Airport?

As of November 2025, there is 1 operator available to choose from for flights from Missouri to Des Moines Airport.

How old do you have to be to fly from Missouri to Des Moines Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Des Moines Airport.

What documentation or ID do you need to fly to Des Moines Airport?

The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$59 Cheap Flights from Missouri to Des Moines in 2025/26

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Find the cheapest flights from Missouri to Des Moines

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Cheap round-trip flights

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8:25 pm - 9:35 pmSTL-DSM

1h 10mnonstop

6:15 am - 7:25 amDSM-STL

1h 10mnonstop

$117Southwest

Find Deal

Wed, Dec 3 - Wed, Dec 10

10:15 am - 11:25 amSTL-DSM

1h 10mnonstop

8:20 am - 1:20 pmDSM-STL

5h 00m1 stop

$127Southwest

Find Deal

Wed, Dec 3 - Wed, Dec 10

10:15 am - 11:25 amSTL-DSM

1h 10mnonstop

6:15 am - 7:25 amDSM-STL

1h 10mnonstop

$144Southwest

Find Deal

Wed, Dec 3 - Wed, Dec 10

3:50 pm - 9:27 pmSTL-DSM

5h 37m1 stop

6:20 am - 1:25 pmDSM-STL

7h 05m1 stop

$157Delta

Find Deal

Tue, Mar 31 - Wed, Apr 1

10:45 am - 4:16 pmSTL-DSM

5h 31m1 stop

6:50 am - 1:53 pmDSM-STL

7h 03m2 stops

$162Delta

Find Deal

Wed, Dec 3 - Wed, Dec 10

6:39 am - 5:03 pmSTL-DSM

10h 24m2 stops

6:50 am - 1:53 pmDSM-STL

7h 03m2 stops

$167Delta

Find Deal

Wed, Dec 3 - Wed, Dec 10

8:25 pm - 9:35 pmSTL-DSM

1h 10mnonstop

6:25 am - 7:45 amDSM-STL

1h 20mnonstop

$171Southwest

Find Deal

Mon, Dec 8 - Sat, Dec 13

6:10 am - 10:17 amSTL-DSM

4h 07m1 stop

12:25 pm - 4:44 pmDSM-STL

4h 19m1 stop

$181Delta

Find Deal

Thu, Feb 26 - Sat, Feb 28

7:05 am - 1:31 pmSTL-DSM

6h 26m1 stop

6:50 am - 1:53 pmDSM-STL

7h 03m2 stops

$186Delta

Find Deal

Mon, Dec 8 - Sat, Dec 13

8:09 pm - 7:03 pmMCI-DSM

22h 54m1 stop

4:21 pm - 7:51 pmDSM-MCI

51h 30m2 stops

$239Multiple Airlines

Find Deal

Thu, Dec 11 - Thu, Dec 18

American Airlines flights from Missouri to Des Moines

Our best American Airlines deals on Missouri to Des Moines flight tickets

American Airlines

Nov 26

STL11:42 amLambert-St Louis

4h 59m

1 stop

DSM4:41 pmDes Moines

Nov 29

DSM5:26 pmDes Moines

5h 08m

1 stop

STL10:34 pmLambert-St Louis

$433

Find similar

American Airlines

Nov 26

STL5:17 amLambert-St Louis

5h 23m

1 stop

DSM10:40 amDes Moines

Nov 29

DSM5:00 amDes Moines

6h 47m

1 stop

STL11:47 amLambert-St Louis

$474

Find similar

American Airlines

Nov 26

STL11:42 amLambert-St Louis

4h 59m

1 stop

DSM4:41 pmDes Moines

Nov 30

DSM8:51 amDes Moines

6h 21m

1 stop

STL3:12 pmLambert-St Louis

$508

Find similar

United Airlines flights from Missouri to Des Moines

Our best United Airlines deals on Missouri to Des Moines flight tickets

United Airlines

Dec 30

STL6:30 amLambert-St Louis

4h 20m

1 stop

DSM10:50 amDes Moines

Jan 2

DSM8:00 amDes Moines

6h 26m

1 stop

STL2:26 pmLambert-St Louis

$266

Find similar

United Airlines

Mar 6

MCI6:00 amKansas City

15h 50m

2 stops

DSM9:50 pmDes Moines

Mar 9

DSM6:45 pmDes Moines

26h 50m

1 stop

MCI9:35 pmKansas City

$616

Find similar

United Airlines

Mar 6

MCI6:00 amKansas City

17h 40m

1 stop

DSM11:40 pmDes Moines

Mar 9

DSM3:15 pmDes Moines

20h 40m

2 stops

MCI11:55 amKansas City

$641

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 12/3

8:25 pm-9:35 pm

Nonstop1h 10m

Des Moines

Wed 12/10

6:15 am-7:25 am

Nonstop1h 10m

$117

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 12/3

10:15 am-11:25 am

Nonstop1h 10m

Des Moines

Wed 12/10

8:20 am-1:20 pm

1 stop5h 00m

$127

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 12/3

10:15 am-11:25 am

Nonstop1h 10m

Des Moines

Wed 12/10

6:15 am-7:25 am

Nonstop1h 10m

$144

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Tue 3/31

3:50 pm-9:27 pm

1 stop5h 37m

Des Moines

Wed 4/1

6:20 am-1:25 pm

1 stop7h 05m

$157

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 12/3

10:45 am-4:16 pm

1 stop5h 31m

Des Moines

Wed 12/10

6:50 am-1:53 pm

2 stops7h 03m

$162

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Wed 12/3

6:39 am-5:03 pm

2 stops10h 24m

Des Moines

Wed 12/10

6:50 am-1:53 pm

2 stops7h 03m

$167

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Mon 12/8

8:25 pm-9:35 pm

Nonstop1h 10m

Des Moines

Sat 12/13

6:25 am-7:45 am

Nonstop1h 20m

$171

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Thu 2/26

6:10 am-10:17 am

1 stop4h 07m

Des Moines

Sat 2/28

12:25 pm-4:44 pm

1 stop4h 19m

$181

St. LouisDes Moines

STL - DSM

STLDSM

Lambert-St Louis

Mon 12/8

7:05 am-1:31 pm

1 stop6h 26m

Des Moines

Sat 12/13

6:50 am-1:53 pm

2 stops7h 03m

$186

Kansas CityDes Moines

MCI - DSM

MCIDSM

Kansas City

Thu 12/11

8:09 pm-7:03 pm

1 stop22h 54m

Des Moines

Thu 12/18

4:21 pm-7:51 pm

2 stops51h 30m

$239

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Missouri to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Missouri to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $381. Flights from Missouri to Des Moines on a Friday will generally be more expensive and average around $492. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the evening. momondo users have found flights departing from Missouri to Des Moines in the evening for as low as $171. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $487. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Missouri to Des Moines flight route?

Fly from Lambert-St Louis to Des Moines for the best Missouri - Des Moines flight prices

What cabin class options are available on Missouri to Des Moines flights?

There is only 1 cabin class available to choose from on Missouri to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Missouri to Des Moines.

Cheap Missouri to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Des Moines

Best Price Found	$501
Fastest flight time	1h 10m
Direct flights	Tue, Wed, Thu, Fri, Sat and Sun
Airports in Des Moines	1 airport

The best flight deal from Missouri to Des Moines found on momondo in the last 72 hours is $501

The fastest flight from Missouri to Des Moines takes 1h 10m

Direct flights go from Missouri to Des Moines on Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.

There is 1 airport near Des Moines: Des Moines (DSM)

Search flight deals

When did momondo last update prices for flights from Missouri to Des Moines Airport?
Prices for flights from Missouri to Des Moines Airport were last updated today.
How many operators does momondo search for flights from Missouri to Des Moines Airport?
As of November 2025, there is 1 operator available to choose from for flights from Missouri to Des Moines Airport.
How old do you have to be to fly from Missouri to Des Moines Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Des Moines Airport.
What documentation or ID do you need to fly to Des Moines Airport?
The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Missouri to Des Moines?
Based on momondo bookings for flights between Missouri and Des Moines, the leading plane model is Boeing 737 MAX 8, making up 25.58% of the total bookings. Other popular models include Boeing 737-800 Passenger/BBJ2 (winglets) with 25.58%, Airbus A320neo with 11.63%, and Boeing 737-700 Passenger/BBJ1 (winglets) with 11.63%.

Best airlines flying from Missouri to Des Moines

Compare and see reviews for airlines that fly from Missouri to Des Moines with momondo

Airline	Rating	Free Cancellation	Price
Southwest	PriceFrom $77	Free Cancellation	Rating 8.0 4,235 reviews		Search Southwest flights
American Airlines	PriceFrom $218	Free Cancellation	Rating 7.2 11,049 reviews		Search American Airlines flights

West Des Moines

Ames

Ankeny

Altoona

Urbandale

Clive

Newton

Pella

Johnston

Osceola

Boone

Norwalk

Grinnell

Oskaloosa

Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Missouri.

Can I find flights from Missouri to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Missouri which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Missouri to Des Moines?

Once you have performed a search for Missouri to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Missouri to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Missouri are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Cheap flights from Missouri to Des Moines from $59

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Des Moines departing on 2/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Filter for what you want

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American Airlines flights from Missouri to Des Moines

Our best American Airlines deals on Missouri to Des Moines flight tickets

United Airlines flights from Missouri to Des Moines

Our best United Airlines deals on Missouri to Des Moines flight tickets

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Use the filters below to find and compare flights from Missouri to Des Moines that are best for you.

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How to get the cheapest flight ticket from Missouri to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Des Moines?

What is the cheapest time of day to depart on your flight to Des Moines?

What is the cheapest Missouri to Des Moines flight route?

Fly from Lambert-St Louis to Des Moines for the best Missouri - Des Moines flight prices

What cabin class options are available on Missouri to Des Moines flights?

There is only 1 cabin class available to choose from on Missouri to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Missouri to Des Moines.

What is the cheapest airline that flies from Missouri to Des Moines?

Southwest, Frontier, and Delta are the most popular carriers operating from Missouri to Des Moines

How many flights depart from Missouri to Des Moines on average per day?

2 flights are operational daily from Missouri to Des Moines as of November 2025. The most popular departure time for this route is 9:00AM, with 37% of flights per day taking off at noon.

How many flights depart from Missouri to Des Moines on average per week?

As of November 2025, 14 flights take off from Missouri and land in Des Moines each week. The most common flight departure day for this route is Mon, with 29% of weekly flights taking off on this day.

How long does it take to fly to Des Moines?

If you’re flying from a popular airport in Missouri, such as St. Louis or Kansas City, and flying into Des Moines, then you can expect flight times to average 1h 10m and 9h 17m, respectively.

Cheap Missouri to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Des Moines

Best Price Found

Fastest flight time

Direct flights

Airports in Des Moines

When did momondo last update prices for flights from Missouri to Des Moines Airport?

How many operators does momondo search for flights from Missouri to Des Moines Airport?

How old do you have to be to fly from Missouri to Des Moines Airport?

What documentation or ID do you need to fly to Des Moines Airport?

What is the most popular plane model from Missouri to Des Moines?

Best airlines flying from Missouri to Des Moines

Compare and see reviews for airlines that fly from Missouri to Des Moines with momondo

Traveling to a place near Des Moines?

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Des Moines?

Can I find flights from Missouri to Des Moines with flexible booking policies on momondo?

How can momondo help me find flights from Missouri to Des Moines?

I’m not ready to book a flight from Missouri to Des Moines right now. Can momondo alert me if prices change?

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Iowa