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Cheap flights from Missouri to Des Moines from $107

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Missouri to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:50 am - 11:30 amSTL  Lambert-St Louis-DSM Des Moines
5h 40m1 stop Chicago Midway
Southwest Logo
6:00 am - 11:00 amDSM  Des Moines-STL Lambert-St Louis
5h 00m1 stop Chicago Midway
$271Southwest
Wed, Oct 28 - Wed, Nov 4
Delta Logo
6:21 am - 10:11 amSTL  Lambert-St Louis-DSM Des Moines
3h 50m1 stop Minneapolis St Paul
Delta Logo
10:57 am - 2:45 pmDSM  Des Moines-STL Lambert-St Louis
3h 48m1 stop Minneapolis St Paul
$271Delta
Wed, Oct 21 - Wed, Oct 28
American Airlines Logo
5:00 am - 8:56 amSTL  Lambert-St Louis-DSM Des Moines
3h 56m1 stop Chicago O'Hare Intl
American Airlines Logo
7:26 pm - 11:59 pmDSM  Des Moines-STL Lambert-St Louis
4h 33m1 stop Chicago O'Hare Intl
$271American Airlines
Mon, Oct 26 - Mon, Nov 2
Southwest Logo
6:10 pm - 11:15 pmSTL  Lambert-St Louis-DSM Des Moines
5h 05m1 stop Chicago Midway
Southwest Logo
4:25 pm - 11:55 pmDSM  Des Moines-STL Lambert-St Louis
7h 30m2 stops Chicago Midway Nashville Intl
$276Southwest
Mon, Oct 26 - Mon, Nov 2
Southwest Logo
10:20 am - 10:00 pmSTL  Lambert-St Louis-DSM Des Moines
11h 40m2 stops Atlanta Hartsfield-Jackson Chicago Midway
Southwest Logo
3:30 pm - 10:00 pmDSM  Des Moines-STL Lambert-St Louis
6h 30m1 stop Chicago Midway
$287Southwest
Wed, Oct 28 - Wed, Nov 4
American Airlines Logo
5:00 am - 8:56 amSTL  Lambert-St Louis-DSM Des Moines
3h 56m1 stop Chicago O'Hare Intl
American Airlines Logo
7:31 pm - 12:19 amDSM  Des Moines-STL Lambert-St Louis
4h 48m1 stop Chicago O'Hare Intl
$289American Airlines
Thu, Oct 22 - Fri, Oct 23
Southwest Logo
2:35 pm - 8:50 pmSTL  Lambert-St Louis-DSM Des Moines
6h 15m1 stop Denver Intl
Southwest Logo
6:10 am - 2:10 pmDSM  Des Moines-STL Lambert-St Louis
8h 00m1 stop Denver Intl
$289Southwest
Thu, Nov 19 - Thu, Nov 26
United Airlines Logo
3:10 pm - 9:55 pmSGF  Springfield-Branson-DSM Des Moines
6h 45m1 stop Chicago O'Hare Intl
United Airlines Logo
6:45 pm - 11:10 pmDSM  Des Moines-SGF Springfield-Branson
4h 25m1 stop Chicago O'Hare Intl
$309United Airlines
Fri, Oct 30 - Sun, Nov 1
United Airlines Logo
6:25 pm - 11:35 pmSGF  Springfield-Branson-DSM Des Moines
5h 10m1 stop Chicago O'Hare Intl
United Airlines Logo
6:55 pm - 11:18 pmDSM  Des Moines-SGF Springfield-Branson
4h 23m1 stop Chicago O'Hare Intl
$324United Airlines
Fri, Oct 16 - Mon, Oct 19
United Airlines Logo
6:25 pm - 11:35 pmSGF  Springfield-Branson-DSM Des Moines
5h 10m1 stop Chicago O'Hare Intl
United Airlines Logo
6:55 pm - 11:18 pmDSM  Des Moines-SGF Springfield-Branson
4h 23m1 stop Chicago O'Hare Intl
$324United Airlines
Sat, Oct 17 - Mon, Oct 19

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Southwest flights from Missouri to Des Moines

Our best Southwest deals on Missouri to Des Moines flight tickets
Southwest
Oct 26
STL6:10 pmLambert-St Louis
5h 05m
1 stop
DSM11:15 pmDes Moines
Nov 2
DSM4:25 pmDes Moines
7h 30m
2 stops
STL11:55 pmLambert-St Louis
$276
Southwest
Oct 28
STL10:20 amLambert-St Louis
11h 40m
2 stops
DSM10:00 pmDes Moines
Nov 4
DSM3:30 pmDes Moines
6h 30m
1 stop
STL10:00 pmLambert-St Louis
$287
Southwest
Nov 19
STL2:20 pmLambert-St Louis
7h 45m
2 stops
DSM10:05 pmDes Moines
Nov 26
DSM6:10 amDes Moines
5h 55m
1 stop
STL12:05 pmLambert-St Louis
$294

Delta flights from Missouri to Des Moines

Our best Delta deals on Missouri to Des Moines flight tickets
Delta
Oct 21
STL6:21 amLambert-St Louis
3h 50m
1 stop
DSM10:11 amDes Moines
Oct 28
DSM10:57 amDes Moines
3h 48m
1 stop
STL2:45 pmLambert-St Louis
$271
Delta
Oct 21
STL6:21 amLambert-St Louis
3h 50m
1 stop
DSM10:11 amDes Moines
Oct 28
DSM6:55 amDes Moines
6h 58m
2 stops
STL1:53 pmLambert-St Louis
$443
Delta
Oct 21
STL6:21 amLambert-St Louis
3h 50m
1 stop
DSM10:11 amDes Moines
Oct 28
DSM6:55 amDes Moines
6h 58m
2 stops
STL1:53 pmLambert-St Louis
$475

momondo Fare Finder

 
Use the filters below to find and compare flights from Missouri to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisDes Moines

STL Lambert-St Louis - DSM Des Moines

STLDSM

Lambert-St Louis

Wed 10/28

5:50 am-11:30 am

1 stop5h 40m

Des Moines

Wed 11/4

6:00 am-11:00 am

1 stop5h 00m

$271
Quickest round-trip

St. LouisDes Moines

STL Lambert-St Louis - DSM Des Moines

STLDSM

Lambert-St Louis

Wed 10/21

6:21 am-10:11 am

1 stop3h 50m

Des Moines

Wed 10/28

10:57 am-2:45 pm

1 stop3h 48m

$271

St. LouisDes Moines

STL Lambert-St Louis - DSM Des Moines

STLDSM

Lambert-St Louis

Mon 10/26

5:00 am-8:56 am

1 stop3h 56m

Des Moines

Mon 11/2

7:26 pm-11:59 pm

1 stop4h 33m

$271

St. LouisDes Moines

STL Lambert-St Louis - DSM Des Moines

STLDSM

Lambert-St Louis

Mon 10/26

6:10 pm-11:15 pm

1 stop5h 05m

Des Moines

Mon 11/2

4:25 pm-11:55 pm

2 stops7h 30m

$276

St. LouisDes Moines

STL Lambert-St Louis - DSM Des Moines

STLDSM

Lambert-St Louis

Wed 10/28

10:20 am-10:00 pm

2 stops11h 40m

Des Moines

Wed 11/4

3:30 pm-10:00 pm

1 stop6h 30m

$287

St. LouisDes Moines

STL Lambert-St Louis - DSM Des Moines

STLDSM

Lambert-St Louis

Thu 10/22

5:00 am-8:56 am

1 stop3h 56m

Des Moines

Fri 10/23

7:31 pm-12:19 am

1 stop4h 48m

$289

St. LouisDes Moines

STL Lambert-St Louis - DSM Des Moines

STLDSM

Lambert-St Louis

Thu 11/19

2:35 pm-8:50 pm

1 stop6h 15m

Des Moines

Thu 11/26

6:10 am-2:10 pm

1 stop8h 00m

$289

SpringfieldDes Moines

SGF Springfield-Branson - DSM Des Moines

SGFDSM

Springfield-Branson

Fri 10/30

3:10 pm-9:55 pm

1 stop6h 45m

Des Moines

Sun 11/1

6:45 pm-11:10 pm

1 stop4h 25m

$309

SpringfieldDes Moines

SGF Springfield-Branson - DSM Des Moines

SGFDSM

Springfield-Branson

Fri 10/16

6:25 pm-11:35 pm

1 stop5h 10m

Des Moines

Mon 10/19

6:55 pm-11:18 pm

1 stop4h 23m

$324

SpringfieldDes Moines

SGF Springfield-Branson - DSM Des Moines

SGFDSM

Springfield-Branson

Sat 10/17

6:25 pm-11:35 pm

1 stop5h 10m

Des Moines

Mon 10/19

6:55 pm-11:18 pm

1 stop4h 23m

$324

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Missouri to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in December, then April is your next best option. Flight prices from Missouri to Des Moines during April average around $0.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Missouri to Des Moines is on a Wednesday. Travelers who choose to depart for Des Moines on a Wednesday will often find tickets for as low as $415. Flights from Missouri to Des Moines on a Thursday will generally be more expensive and average around $467. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Missouri to Des Moines in the morning for as low as $501. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the evening because they tend to be around $680. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Missouri to Des Moines flight route?

Fly from Lambert-St Louis to Des Moines for the best Missouri - Des Moines flight prices

What cabin class options are available on Missouri to Des Moines flights?

There is only 1 cabin class available to choose from on Missouri to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Des Moines flights?

You could potentially save up to 20% on your flight if you consider stops on a Missouri to Des Moines flight.

Cheap Missouri to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Des Moines

Best Price Found

$107

Fastest flight time

3h 50m

Direct flights

None
The best one-way flight to Des Moines from Missouri in the past 72 hours is $107. The best round-trip flight deal from Missouri to Des Moines found on momondo in the last 72 hours is $271.
The fastest flight from Missouri to Des Moines takes 3h 50m
There are no direct flights from Missouri to Des Moines. There are no popular flight routes from Missouri to Des Moines.
Search flight deals

Frequently asked questions about flying from Missouri to Des Moines

  • When did momondo last update prices for flights from Missouri to Des Moines Airport?

    Prices for flights from Missouri to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Missouri to Des Moines Airport?

  • How old do you have to be to fly from Missouri to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Missouri to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Missouri to Des Moines?

Best airlines flying from Missouri to Des Moines

Compare and see reviews for airlines that fly from Missouri to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
SouthwestPriceFrom $77Free CancellationRating
8.0
4,207 reviews
Search Southwest flights
United AirlinesPriceFrom $262Free CancellationRating
7.4
10,270 reviews
Search United Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Osceola
Urbandale
Newton
Boone
Johnston
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Missouri.

Can I find flights from Missouri to Des Moines with flexible booking policies on momondo?

momondo does allow users to show only those flights to Des Moines from Missouri which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Missouri to Des Moines?

Once you have performed a search for Missouri to Des Moines flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Missouri to Des Moines right now. Can momondo alert me if prices change?

Price alerts on flights to Des Moines from Missouri are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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