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Cheap flights from Mississippi to Roanoke from $269

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Roanoke departing on 4/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Mississippi to Roanoke

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
8:06 am - 2:33 pm
MEM
-
ROA
5h 27m
1 stop
Delta Logo
6:00 am - 9:35 am
ROA
-
MEM
4h 35m
1 stop
$269Delta
Wed, Apr 1 - Wed, Apr 15
American Airlines Logo
5:00 am - 10:37 am
MEM
-
ROA
4h 37m
1 stop
American Airlines Logo
8:09 am - 2:23 pm
ROA
-
MEM
7h 14m
2 stops
$274American Airlines
Wed, Apr 1 - Wed, Apr 15
Delta Logo
7:36 pm - 12:04 am
MEM
-
ROA
3h 28m
1 stop
Delta Logo
6:00 am - 9:25 am
ROA
-
MEM
4h 25m
1 stop
$279Delta
Fri, Mar 13 - Tue, Mar 17
United Airlines Logo
7:15 am - 1:33 pm
MEM
-
ROA
5h 18m
1 stop
United Airlines Logo
5:45 pm - 9:59 pm
ROA
-
MEM
5h 14m
1 stop
$299United Airlines
Thu, Jun 25 - Mon, Jun 29
American Airlines Logo
8:23 am - 2:25 pm
MEM
-
ROA
5h 02m
1 stop
American Airlines Logo
8:00 pm - 11:51 pm
ROA
-
MEM
4h 51m
1 stop
$304American Airlines
Tue, Mar 17 - Sat, Mar 21
American Airlines Logo
6:00 am - 4:33 pm
MEM
-
ROA
9h 33m
2 stops
American Airlines Logo
8:00 pm - 11:51 pm
ROA
-
MEM
4h 51m
1 stop
$310American Airlines
Tue, Mar 17 - Sat, Mar 21
United Airlines Logo
7:30 am - 7:10 pm
MEM
-
ROA
10h 40m
2 stops
United Airlines Logo
10:34 am - 5:47 pm
ROA
-
MEM
8h 13m
2 stops
$354United Airlines
Wed, Apr 1 - Wed, Apr 15
Delta Logo
5:37 pm - 12:04 am
MEM
-
ROA
5h 27m
1 stop
Delta Logo
6:00 am - 9:25 am
ROA
-
MEM
4h 25m
1 stop
$369Delta
Sat, Mar 21 - Tue, Mar 24
United Airlines Logo
7:15 am - 1:33 pm
MEM
-
ROA
5h 18m
1 stop
United Airlines Logo
10:30 am - 9:59 pm
ROA
-
MEM
12h 29m
2 stops
$386United Airlines
Thu, Jun 25 - Mon, Jun 29
American Airlines Logo
7:01 am - 11:52 pm
MEM
-
ROA
15h 51m
1 stop
American Airlines Logo
8:15 am - 5:11 pm
ROA
-
MEM
9h 56m
2 stops
$460American Airlines
Sat, Mar 21 - Tue, Mar 24

Delta flights from Mississippi to Roanoke

Our best Delta deals on Mississippi to Roanoke flight tickets
Delta
Apr 1
MEM8:06 amMemphis
5h 27m
1 stop
ROA2:33 pmRoanoke
Apr 15
ROA6:00 amRoanoke
4h 35m
1 stop
MEM9:35 amMemphis
$269
Delta
Mar 13
MEM7:36 pmMemphis
3h 28m
1 stop
ROA12:04 amRoanoke
Mar 17
ROA6:00 amRoanoke
4h 25m
1 stop
MEM9:25 amMemphis
$279
Delta
Mar 21
MEM5:37 pmMemphis
5h 27m
1 stop
ROA12:04 amRoanoke
Mar 24
ROA6:00 amRoanoke
4h 25m
1 stop
MEM9:25 amMemphis
$369

American Airlines flights from Mississippi to Roanoke

Our best American Airlines deals on Mississippi to Roanoke flight tickets
American Airlines
Apr 1
MEM5:00 amMemphis
4h 37m
1 stop
ROA10:37 amRoanoke
Apr 15
ROA8:09 amRoanoke
7h 14m
2 stops
MEM2:23 pmMemphis
$274
American Airlines
Mar 17
MEM8:23 amMemphis
5h 02m
1 stop
ROA2:25 pmRoanoke
Mar 21
ROA8:00 pmRoanoke
4h 51m
1 stop
MEM11:51 pmMemphis
$304
American Airlines
Mar 17
MEM6:00 amMemphis
9h 33m
2 stops
ROA4:33 pmRoanoke
Mar 21
ROA8:00 pmRoanoke
4h 51m
1 stop
MEM11:51 pmMemphis
$310

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 4/1

8:06 am-2:33 pm

1 stop5h 27m

Roanoke

Wed 4/15

6:00 am-9:35 am

1 stop4h 35m

$269

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 4/1

5:00 am-10:37 am

1 stop4h 37m

Roanoke

Wed 4/15

8:09 am-2:23 pm

2 stops7h 14m

$274

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 3/13

7:36 pm-12:04 am

1 stop3h 28m

Roanoke

Tue 3/17

6:00 am-9:25 am

1 stop4h 25m

$279

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Thu 6/25

7:15 am-1:33 pm

1 stop5h 18m

Roanoke

Mon 6/29

5:45 pm-9:59 pm

1 stop5h 14m

$299

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 3/17

8:23 am-2:25 pm

1 stop5h 02m

Roanoke

Sat 3/21

8:00 pm-11:51 pm

1 stop4h 51m

$304

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 3/17

6:00 am-4:33 pm

2 stops9h 33m

Roanoke

Sat 3/21

8:00 pm-11:51 pm

1 stop4h 51m

$310

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 4/1

7:30 am-7:10 pm

2 stops10h 40m

Roanoke

Wed 4/15

10:34 am-5:47 pm

2 stops8h 13m

$354

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Sat 3/21

5:37 pm-12:04 am

1 stop5h 27m

Roanoke

Tue 3/24

6:00 am-9:25 am

1 stop4h 25m

$369

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Thu 6/25

7:15 am-1:33 pm

1 stop5h 18m

Roanoke

Mon 6/29

10:30 am-9:59 pm

2 stops12h 29m

$386

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Sat 3/21

7:01 am-11:52 pm

1 stop15h 51m

Roanoke

Tue 3/24

8:15 am-5:11 pm

2 stops9h 56m

$460

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Roanoke from

How to get the cheapest flight ticket from Mississippi to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Mississippi to Roanoke?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Mississippi to Roanoke

Cheap Mississippi to Roanoke flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Roanoke

Fastest flight time

4h 00m

Direct flights

None
The fastest flight from Mississippi to Roanoke takes 4h 00m
There are no direct flights from Mississippi to Roanoke. There are no popular flight routes from Mississippi to Roanoke.
Search flight deals

  • When did momondo last update prices for flights from Mississippi to Roanoke Airport?

    Prices for flights from Mississippi to Roanoke Airport are updated daily.

  • How many operators does momondo search for flights from Mississippi to Roanoke Airport?

  • How old do you have to be to fly from Mississippi to Roanoke Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Roanoke Airport.

  • What documentation or ID do you need to fly to Roanoke Airport?

    The travel and health documents you'll need for your trip to Roanoke Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Roanoke Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Blacksburg
Salem
Christiansburg
Radford
Rocky Mount

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Roanoke?

It is quick and easy to find Mississippi to Roanoke flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Roanoke that suits you.

Can I find flights from Mississippi to Roanoke with flexible booking policies on momondo?

All flight searches from Mississippi to Roanoke on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Mississippi to Roanoke?

momondo helps you find the best flight between Mississippi and Roanoke by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mississippi to Roanoke right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mississippi to Roanoke now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Roanoke and let you know when they change.

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