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Cheap flights from Mississippi to Roanoke from $214

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Roanoke departing on 5/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Find the cheapest flights from Mississippi to Roanoke

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:39 pm - 11:37 pm
JAN
-
ROA
3h 58m
1 stop
American Airlines Logo
7:45 pm - 11:59 pm
ROA
-
JAN
5h 14m
1 stop
$310American Airlines
Fri, May 8 - Sat, May 9
American Airlines Logo
6:39 pm - 11:37 pm
JAN
-
ROA
3h 58m
1 stop
American Airlines Logo
8:09 am - 6:09 pm
ROA
-
JAN
11h 00m
2 stops
$315American Airlines
Fri, May 8 - Sat, May 9
Delta Logo
5:15 am - 10:28 am
MEM
-
ROA
4h 13m
1 stop
Delta Logo
6:00 am - 8:50 am
ROA
-
MEM
3h 50m
1 stop
$329Delta
Tue, May 5 - Sat, May 9
American Airlines Logo
8:17 am - 5:33 pm
MEM
-
ROA
8h 16m
2 stops
American Airlines Logo
8:09 am - 12:28 pm
ROA
-
MEM
5h 19m
1 stop
$334American Airlines
Tue, May 5 - Sat, May 9
Delta Logo
5:59 pm - 12:25 am
MEM
-
ROA
5h 26m
1 stop
Delta Logo
7:50 pm - 11:26 pm
ROA
-
MEM
4h 36m
1 stop
$339Delta
Wed, Apr 29 - Mon, May 4
United Airlines Logo
7:30 am - 1:29 pm
MEM
-
ROA
4h 59m
1 stop
United Airlines Logo
10:34 am - 10:04 pm
ROA
-
MEM
12h 30m
2 stops
$344United Airlines
Wed, Apr 29 - Mon, May 4
Delta Logo
5:15 am - 10:32 am
MEM
-
ROA
4h 17m
1 stop
Delta Logo
7:57 pm - 11:26 pm
ROA
-
MEM
4h 29m
1 stop
$389Delta
Thu, Jun 25 - Mon, Jun 29
United Airlines Logo
9:50 am - 7:10 pm
MEM
-
ROA
8h 20m
2 stops
United Airlines Logo
10:34 am - 10:04 pm
ROA
-
MEM
12h 30m
2 stops
$404United Airlines
Wed, Apr 29 - Mon, May 4
American Airlines Logo
6:00 am - 5:33 pm
JAN
-
ROA
10h 33m
2 stops
American Airlines Logo
8:09 am - 6:09 pm
ROA
-
JAN
11h 00m
2 stops
$414American Airlines
Fri, May 8 - Sat, May 9
United Airlines Logo
6:30 pm - 12:24 am
MEM
-
ROA
4h 54m
1 stop
United Airlines Logo
3:00 pm - 11:30 pm
ROA
-
MEM
9h 30m
2 stops
$429United Airlines
Fri, Jun 12 - Mon, Jun 15

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Delta flights from Mississippi to Roanoke

Our best Delta deals on Mississippi to Roanoke flight tickets
Delta
May 5
MEM5:15 amMemphis
4h 13m
1 stop
ROA10:28 amRoanoke
May 9
ROA6:00 amRoanoke
3h 50m
1 stop
MEM8:50 amMemphis
$329
Delta
Apr 29
MEM5:59 pmMemphis
5h 26m
1 stop
ROA12:25 amRoanoke
May 4
ROA7:50 pmRoanoke
4h 36m
1 stop
MEM11:26 pmMemphis
$339
Delta
Jun 25
MEM5:15 amMemphis
4h 17m
1 stop
ROA10:32 amRoanoke
Jun 29
ROA7:57 pmRoanoke
4h 29m
1 stop
MEM11:26 pmMemphis
$389

American Airlines flights from Mississippi to Roanoke

Our best American Airlines deals on Mississippi to Roanoke flight tickets
American Airlines
May 8
JAN6:39 pmJackson-Evers Intl
3h 58m
1 stop
ROA11:37 pmRoanoke
May 9
ROA7:45 pmRoanoke
5h 14m
1 stop
JAN11:59 pmJackson-Evers Intl
$310
American Airlines
May 8
JAN6:39 pmJackson-Evers Intl
3h 58m
1 stop
ROA11:37 pmRoanoke
May 9
ROA8:09 amRoanoke
11h 00m
2 stops
JAN6:09 pmJackson-Evers Intl
$315
American Airlines
May 5
MEM8:17 amMemphis
8h 16m
2 stops
ROA5:33 pmRoanoke
May 9
ROA8:09 amRoanoke
5h 19m
1 stop
MEM12:28 pmMemphis
$334

momondo Fare Finder

 
Customize your flight search to find flights from Mississippi to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 15, 2026.
Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Fri 5/8

6:39 pm-11:37 pm

1 stop3h 58m

Roanoke

Sat 5/9

7:45 pm-11:59 pm

1 stop5h 14m

$310

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Fri 5/8

6:39 pm-11:37 pm

1 stop3h 58m

Roanoke

Sat 5/9

8:09 am-6:09 pm

2 stops11h 00m

$315
Quickest round-trip

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 5/5

5:15 am-10:28 am

1 stop4h 13m

Roanoke

Sat 5/9

6:00 am-8:50 am

1 stop3h 50m

$329

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 5/5

8:17 am-5:33 pm

2 stops8h 16m

Roanoke

Sat 5/9

8:09 am-12:28 pm

1 stop5h 19m

$334

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 4/29

5:59 pm-12:25 am

1 stop5h 26m

Roanoke

Mon 5/4

7:50 pm-11:26 pm

1 stop4h 36m

$339

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 4/29

7:30 am-1:29 pm

1 stop4h 59m

Roanoke

Mon 5/4

10:34 am-10:04 pm

2 stops12h 30m

$344

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Thu 6/25

5:15 am-10:32 am

1 stop4h 17m

Roanoke

Mon 6/29

7:57 pm-11:26 pm

1 stop4h 29m

$389

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 4/29

9:50 am-7:10 pm

2 stops8h 20m

Roanoke

Mon 5/4

10:34 am-10:04 pm

2 stops12h 30m

$404

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Fri 5/8

6:00 am-5:33 pm

2 stops10h 33m

Roanoke

Sat 5/9

8:09 am-6:09 pm

2 stops11h 00m

$414

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 6/12

6:30 pm-12:24 am

1 stop4h 54m

Roanoke

Mon 6/15

3:00 pm-11:30 pm

2 stops9h 30m

$429

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Roanoke from

How to get the cheapest flight ticket from Mississippi to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Mississippi to Roanoke?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Mississippi to Roanoke

Cheap Mississippi to Roanoke flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Roanoke

Fastest flight time

4h 19m

Direct flights

None
The fastest flight from Mississippi to Roanoke takes 4h 19m
There are no direct flights from Mississippi to Roanoke. There are no popular flight routes from Mississippi to Roanoke.
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Frequently asked questions about flying from Mississippi to Roanoke

  • When did momondo last update prices for flights from Mississippi to Roanoke Airport?

    Prices for flights from Mississippi to Roanoke Airport are updated daily.

  • How many operators does momondo search for flights from Mississippi to Roanoke Airport?

  • How old do you have to be to fly from Mississippi to Roanoke Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Roanoke Airport.

  • What documentation or ID do you need to fly to Roanoke Airport?

    The travel and health documents you'll need for your trip to Roanoke Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Roanoke Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Blacksburg
Salem
Christiansburg
Radford
Rocky Mount

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Roanoke?

It is quick and easy to find Mississippi to Roanoke flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Roanoke that suits you.

Can I find flights from Mississippi to Roanoke with flexible booking policies on momondo?

All flight searches from Mississippi to Roanoke on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Mississippi to Roanoke?

momondo helps you find the best flight between Mississippi and Roanoke by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mississippi to Roanoke right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mississippi to Roanoke now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Roanoke and let you know when they change.

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