What is the cheapest airline that flies from Mississippi to Roanoke?

Delta and American Airlines are the most popular carriers operating from Mississippi to Roanoke

When did momondo last update prices for flights from Mississippi to Roanoke Airport?

Prices for flights from Mississippi to Roanoke Airport are updated daily.

How many operators does momondo search for flights from Mississippi to Roanoke Airport?

As of November 2025, there are 2 operators available to choose from for flights from Mississippi to Roanoke Airport.

How old do you have to be to fly from Mississippi to Roanoke Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Roanoke Airport.

What documentation or ID do you need to fly to Roanoke Airport?

The travel and health documents you'll need for your trip to Roanoke Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Roanoke Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$239 Cheap Flights from Mississippi to Roanoke in 2025/26

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Find the cheapest flights from Mississippi to Roanoke

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One-way

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5:22 pm - 12:06 amMEM-ROA

5h 44m1 stop

6:47 pm - 11:18 pmROA-MEM

5h 31m1 stop

$249Delta

Find Deal

Fri, Jan 9 - Mon, Jan 12

9:28 am - 2:49 pmJAN-ROA

4h 21m1 stop

7:59 pm - 11:13 pmROA-JAN

4h 14m1 stop

$249Delta

Find Deal

Wed, Feb 18 - Sat, Feb 21

6:35 am - 4:10 pmMEM-ROA

8h 35m2 stops

12:43 pm - 7:03 pmROA-MEM

7h 20m1 stop

$254American Airlines

Find Deal

Fri, Jan 9 - Mon, Jan 12

5:45 am - 10:33 amJAN-ROA

3h 48m1 stop

7:50 pm - 11:23 pmROA-JAN

4h 33m1 stop

$264Delta

Find Deal

Wed, Feb 18 - Sat, Feb 21

5:55 pm - 10:56 pmMEM-ROA

4h 01m1 stop

8:00 pm - 11:55 pmROA-MEM

4h 55m1 stop

$294American Airlines

Find Deal

Tue, Feb 17 - Sun, Feb 22

6:44 am - 4:42 pmMEM-ROA

8h 58m2 stops

8:00 pm - 11:55 pmROA-MEM

4h 55m1 stop

$299American Airlines

Find Deal

Tue, Feb 17 - Sun, Feb 22

5:30 am - 10:41 amJAN-ROA

4h 11m1 stop

7:59 pm - 11:13 pmROA-JAN

4h 14m1 stop

$319Delta

Find Deal

Wed, Feb 18 - Sat, Feb 21

9:55 am - 8:02 pmMEM-ROA

9h 07m2 stops

2:55 pm - 9:59 pmROA-MEM

8h 04m2 stops

$388United Airlines

Find Deal

Fri, Jan 9 - Mon, Jan 12

7:30 am - 8:07 pmMEM-ROA

11h 37m2 stops

2:47 pm - 9:59 pmROA-MEM

8h 12m2 stops

$474United Airlines

Find Deal

Tue, Feb 17 - Sun, Feb 22

10:30 am - 4:56 pmMEM-ROA

5h 26m1 stop

6:20 am - 2:45 pmROA-MEM

9h 25m2 stops

$517United Airlines

Find Deal

Wed, Nov 19 - Sun, Nov 23

Delta flights from Mississippi to Roanoke

Our best Delta deals on Mississippi to Roanoke flight tickets

Delta

Jan 9

MEM5:22 pmMemphis

5h 44m

1 stop

ROA12:06 amRoanoke

Jan 12

ROA6:47 pmRoanoke

5h 31m

1 stop

MEM11:18 pmMemphis

$249

Find similar

Delta

Feb 18

JAN5:45 amJackson-Evers Intl

3h 48m

1 stop

ROA10:33 amRoanoke

Feb 21

ROA7:50 pmRoanoke

4h 33m

1 stop

JAN11:23 pmJackson-Evers Intl

$264

Find similar

Delta

Feb 18

JAN5:30 amJackson-Evers Intl

4h 11m

1 stop

ROA10:41 amRoanoke

Feb 21

ROA7:59 pmRoanoke

4h 14m

1 stop

JAN11:13 pmJackson-Evers Intl

$319

Find similar

American Airlines flights from Mississippi to Roanoke

Our best American Airlines deals on Mississippi to Roanoke flight tickets

American Airlines

Jan 9

MEM6:35 amMemphis

8h 35m

2 stops

ROA4:10 pmRoanoke

Jan 12

ROA12:43 pmRoanoke

7h 20m

1 stop

MEM7:03 pmMemphis

$254

Find similar

American Airlines

Feb 17

MEM5:55 pmMemphis

4h 01m

1 stop

ROA10:56 pmRoanoke

Feb 22

ROA8:00 pmRoanoke

4h 55m

1 stop

MEM11:55 pmMemphis

$294

Find similar

American Airlines

Feb 17

MEM6:44 amMemphis

8h 58m

2 stops

ROA4:42 pmRoanoke

Feb 22

ROA8:00 pmRoanoke

4h 55m

1 stop

MEM11:55 pmMemphis

$299

Find similar

Fly from

Fly to

Route

Depart

Return

Price

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 1/9

5:22 pm-12:06 am

1 stop5h 44m

Roanoke

Mon 1/12

6:47 pm-11:18 pm

1 stop5h 31m

$249

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 2/18

9:28 am-2:49 pm

1 stop4h 21m

Roanoke

Sat 2/21

7:59 pm-11:13 pm

1 stop4h 14m

$249

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 1/9

6:35 am-4:10 pm

2 stops8h 35m

Roanoke

Mon 1/12

12:43 pm-7:03 pm

1 stop7h 20m

$254

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 2/18

5:45 am-10:33 am

1 stop3h 48m

Roanoke

Sat 2/21

7:50 pm-11:23 pm

1 stop4h 33m

$264

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 2/17

5:55 pm-10:56 pm

1 stop4h 01m

Roanoke

Sun 2/22

8:00 pm-11:55 pm

1 stop4h 55m

$294

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 2/17

6:44 am-4:42 pm

2 stops8h 58m

Roanoke

Sun 2/22

8:00 pm-11:55 pm

1 stop4h 55m

$299

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

Wed 2/18

5:30 am-10:41 am

1 stop4h 11m

Roanoke

Sat 2/21

7:59 pm-11:13 pm

1 stop4h 14m

$319

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Fri 1/9

9:55 am-8:02 pm

2 stops9h 07m

Roanoke

Mon 1/12

2:55 pm-9:59 pm

2 stops8h 04m

$388

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Tue 2/17

7:30 am-8:07 pm

2 stops11h 37m

Roanoke

Sun 2/22

2:47 pm-9:59 pm

2 stops8h 12m

$474

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

Wed 11/19

10:30 am-4:56 pm

1 stop5h 26m

Roanoke

Sun 11/23

6:20 am-2:45 pm

2 stops9h 25m

$517

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first

How to get the cheapest flight ticket from Mississippi to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Roanoke?

Our data shows that Tuesday is the least expensive day to fly to Roanoke. Tickets to fly out on this day can be as low as $454. Flights from Mississippi to Roanoke on a Thursday will generally be more expensive and average around $717. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Roanoke?

Our most recent data shows that the best time of day to fly to Roanoke is in the afternoon. Flights from Mississippi to Roanoke during this time can be as low as $447. In contrast, the most expensive time of day to depart to Roanoke is in the morning when prices are around $575.

Cheap Mississippi to Roanoke flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Roanoke

Direct flights	None

There are no direct flights from Mississippi to Roanoke. There are no popular flight routes from Mississippi to Roanoke.

Search flight deals

When did momondo last update prices for flights from Mississippi to Roanoke Airport?
Prices for flights from Mississippi to Roanoke Airport are updated daily.
How many operators does momondo search for flights from Mississippi to Roanoke Airport?
As of November 2025, there are 2 operators available to choose from for flights from Mississippi to Roanoke Airport.
How old do you have to be to fly from Mississippi to Roanoke Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Roanoke Airport.
What documentation or ID do you need to fly to Roanoke Airport?
The travel and health documents you'll need for your trip to Roanoke Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Roanoke Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Salem

Blacksburg

Christiansburg

Radford

Rocky Mount

Lafayette

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Roanoke?

It is quick and easy to find Mississippi to Roanoke flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Roanoke that suits you.

Can I find flights from Mississippi to Roanoke with flexible booking policies on momondo?

All flight searches from Mississippi to Roanoke on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Mississippi to Roanoke?

momondo helps you find the best flight between Mississippi and Roanoke by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mississippi to Roanoke right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mississippi to Roanoke now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Roanoke and let you know when they change.

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Cheap flights from Mississippi to Roanoke from $239

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Roanoke departing on 1/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Mississippi to Roanoke

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Delta flights from Mississippi to Roanoke

Our best Delta deals on Mississippi to Roanoke flight tickets

American Airlines flights from Mississippi to Roanoke

Our best American Airlines deals on Mississippi to Roanoke flight tickets

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Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

See travel insights to Roanoke from

How to get the cheapest flight ticket from Mississippi to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Roanoke?

What is the cheapest time of day to depart on your flight to Roanoke?

Our most recent data shows that the best time of day to fly to Roanoke is in the afternoon. Flights from Mississippi to Roanoke during this time can be as low as $447. In contrast, the most expensive time of day to depart to Roanoke is in the morning when prices are around $575.

What is the cheapest airline that flies from Mississippi to Roanoke?

Delta and American Airlines are the most popular carriers operating from Mississippi to Roanoke

Cheap Mississippi to Roanoke flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Roanoke

Direct flights

When did momondo last update prices for flights from Mississippi to Roanoke Airport?

How many operators does momondo search for flights from Mississippi to Roanoke Airport?

How old do you have to be to fly from Mississippi to Roanoke Airport?

What documentation or ID do you need to fly to Roanoke Airport?

Traveling to a place near Roanoke?

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Roanoke?

Can I find flights from Mississippi to Roanoke with flexible booking policies on momondo?

How can momondo help me find flights from Mississippi to Roanoke?

I’m not ready to book a flight from Mississippi to Roanoke right now. Can momondo alert me if prices change?

An easier way to manage your Roanoke trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Virginia