What is the cheapest airline that flies from Mississippi to Roanoke?

Delta, American Airlines, and United Airlines are the most popular carriers operating from Mississippi to Roanoke

When did momondo last update prices for flights from Mississippi to Roanoke Airport?

Prices for flights from Mississippi to Roanoke Airport are updated daily.

How many operators does momondo search for flights from Mississippi to Roanoke Airport?

As of September 2025, there are 2 operators available to choose from for flights from Mississippi to Roanoke Airport.

How old do you have to be to fly from Mississippi to Roanoke Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Roanoke Airport.

What documentation or ID do you need to fly to Roanoke Airport?

The travel and health documents you'll need for your trip to Roanoke Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Roanoke Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$136 Cheap Flights from Mississippi to Roanoke in 2025

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Find the cheapest flights from Mississippi to Roanoke

Round-trip

One-way

Last minute

Cheap round-trip flights

5:35 pm - 11:49 pmJAN-ROA

5h 14m1 stop

3:25 pm - 8:08 pmROA-JAN

5h 43m1 stop

$249Delta

Find Deal

mié., feb. 18 - sáb., feb. 21

6:06 pm - 12:09 amMEM-ROA

5h 03m1 stop

7:55 pm - 11:20 pmROA-MEM

4h 25m1 stop

$269Delta

Find Deal

vie., nov. 7 - lun., nov. 10

5:35 pm - 11:49 pmJAN-ROA

5h 14m1 stop

3:25 pm - 6:06 pmROA-JAN

3h 41m1 stop

$269Delta

Find Deal

mié., feb. 18 - sáb., feb. 21

10:48 am - 4:40 pmMEM-ROA

4h 52m1 stop

8:06 pm - 11:59 pmROA-MEM

4h 53m1 stop

$299American Airlines

Find Deal

vie., nov. 21 - dom., nov. 23

7:20 pm - 12:09 amMEM-ROA

3h 49m1 stop

6:00 am - 8:31 amROA-MEM

3h 31m1 stop

$314Delta

Find Deal

vie., oct. 24 - dom., oct. 26

7:31 am - 4:25 pmJAN-ROA

7h 54m2 stops

5:22 am - 10:17 amROA-JAN

5h 55m1 stop

$324American Airlines

Find Deal

mié., feb. 18 - sáb., feb. 21

3:15 pm - 8:39 pmMEM-ROA

4h 24m1 stop

3:00 pm - 9:53 pmROA-MEM

7h 53m2 stops

$324United Airlines

Find Deal

sáb., feb. 21 - mié., feb. 25

7:31 am - 4:25 pmJAN-ROA

7h 54m2 stops

8:30 am - 7:14 pmROA-JAN

11h 44m2 stops

$329American Airlines

Find Deal

mié., feb. 18 - sáb., feb. 21

7:50 am - 6:38 pmMEM-ROA

9h 48m2 stops

10:30 am - 5:23 pmROA-MEM

7h 53m2 stops

$359United Airlines

Find Deal

sáb., feb. 21 - mié., feb. 25

2:50 pm - 9:19 pmMEM-ROA

5h 29m1 stop

5:40 pm - 9:43 pmROA-MEM

5h 03m1 stop

$413United Airlines

Find Deal

jue., sep. 18 - lun., sep. 22

American Airlines flights from Mississippi to Roanoke

Our best American Airlines deals on Mississippi to Roanoke flight tickets

American Airlines

Nov 21

MEM10:48 amMemphis

4h 52m

1 stop

ROA4:40 pmRoanoke

Nov 23

ROA8:06 pmRoanoke

4h 53m

1 stop

MEM11:59 pmMemphis

$299

Find similar

American Airlines

Sep 9

MEM6:00 amMemphis

7h 36m

1 stop

ROA2:36 pmRoanoke

Sep 23

ROA5:18 pmRoanoke

6h 41m

1 stop

MEM10:59 pmMemphis

$319

Find similar

American Airlines

Feb 18

JAN7:31 amJackson-Evers Intl

7h 54m

2 stops

ROA4:25 pmRoanoke

Feb 21

ROA5:22 amRoanoke

5h 55m

1 stop

JAN10:17 amJackson-Evers Intl

$324

Find similar

United Airlines flights from Mississippi to Roanoke

Our best United Airlines deals on Mississippi to Roanoke flight tickets

United Airlines

Sep 9

MEM11:00 amMemphis

11h 24m

2 stops

ROA11:24 pmRoanoke

Sep 23

ROA5:40 pmRoanoke

5h 03m

1 stop

MEM9:43 pmMemphis

$304

Find similar

United Airlines

Sep 9

MEM11:00 amMemphis

11h 24m

2 stops

ROA11:24 pmRoanoke

Sep 23

ROA6:20 amRoanoke

10h 08m

2 stops

MEM3:28 pmMemphis

$309

Find similar

United Airlines

Feb 21

MEM3:15 pmMemphis

4h 24m

1 stop

ROA8:39 pmRoanoke

Feb 25

ROA3:00 pmRoanoke

7h 53m

2 stops

MEM9:53 pmMemphis

$324

Find similar

Fly from

Fly to

Route

Depart

Return

Price

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

mié. 2/18

5:35 pm-11:49 pm

1 stop5h 14m

Roanoke

sáb. 2/21

3:25 pm-8:08 pm

1 stop5h 43m

$249

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

vie. 11/7

6:06 pm-12:09 am

1 stop5h 03m

Roanoke

lun. 11/10

7:55 pm-11:20 pm

1 stop4h 25m

$269

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

mié. 2/18

5:35 pm-11:49 pm

1 stop5h 14m

Roanoke

sáb. 2/21

3:25 pm-6:06 pm

1 stop3h 41m

$269

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

vie. 11/21

10:48 am-4:40 pm

1 stop4h 52m

Roanoke

dom. 11/23

8:06 pm-11:59 pm

1 stop4h 53m

$299

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

vie. 10/24

7:20 pm-12:09 am

1 stop3h 49m

Roanoke

dom. 10/26

6:00 am-8:31 am

1 stop3h 31m

$314

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

mié. 2/18

7:31 am-4:25 pm

2 stops7h 54m

Roanoke

sáb. 2/21

5:22 am-10:17 am

1 stop5h 55m

$324

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

sáb. 2/21

3:15 pm-8:39 pm

1 stop4h 24m

Roanoke

mié. 2/25

3:00 pm-9:53 pm

2 stops7h 53m

$324

JacksonRoanoke

JAN - ROA

JANROA

Jackson-Evers Intl

mié. 2/18

7:31 am-4:25 pm

2 stops7h 54m

Roanoke

sáb. 2/21

8:30 am-7:14 pm

2 stops11h 44m

$329

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

sáb. 2/21

7:50 am-6:38 pm

2 stops9h 48m

Roanoke

mié. 2/25

10:30 am-5:23 pm

2 stops7h 53m

$359

MemphisRoanoke

MEM - ROA

MEMROA

Memphis

jue. 9/18

2:50 pm-9:19 pm

1 stop5h 29m

Roanoke

lun. 9/22

5:40 pm-9:43 pm

1 stop5h 03m

$413

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Mississippi to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest day to depart on your flight to Roanoke?

Our data shows that Tuesday is the least expensive day to fly to Roanoke. Tickets to fly out on this day can be as low as $454. Flights from Mississippi to Roanoke on a Thursday will generally be more expensive and average around $717. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Roanoke?

Our most recent data shows that the best time of day to fly to Roanoke is in the afternoon. Flights from Mississippi to Roanoke during this time can be as low as $447. In contrast, the most expensive time of day to depart to Roanoke is in the morning when prices are around $575.

Cheap Mississippi to Roanoke flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Roanoke

Direct flights	None

There are no direct flights from Mississippi to Roanoke. There are no popular flight routes from Mississippi to Roanoke.

Search flight deals

When did momondo last update prices for flights from Mississippi to Roanoke Airport?
Prices for flights from Mississippi to Roanoke Airport are updated daily.
How many operators does momondo search for flights from Mississippi to Roanoke Airport?
As of September 2025, there are 2 operators available to choose from for flights from Mississippi to Roanoke Airport.
How old do you have to be to fly from Mississippi to Roanoke Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Mississippi to Roanoke Airport.
What documentation or ID do you need to fly to Roanoke Airport?
The travel and health documents you'll need for your trip to Roanoke Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Roanoke Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Salem

Christiansburg

Blacksburg

Radford

Rocky Mount

Lafayette

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Roanoke?

It is quick and easy to find Mississippi to Roanoke flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Roanoke that suits you.

Can I find flights from Mississippi to Roanoke with flexible booking policies on momondo?

All flight searches from Mississippi to Roanoke on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Mississippi to Roanoke?

momondo helps you find the best flight between Mississippi and Roanoke by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Mississippi to Roanoke right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Mississippi to Roanoke now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Roanoke and let you know when they change.

An easier way to manage your Roanoke trip

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Cheap flights from Mississippi to Roanoke from $136

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Mississippi to Roanoke departing on 12/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

Find the cheapest flights from Mississippi to Roanoke

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

American Airlines flights from Mississippi to Roanoke

Our best American Airlines deals on Mississippi to Roanoke flight tickets

United Airlines flights from Mississippi to Roanoke

Our best United Airlines deals on Mississippi to Roanoke flight tickets

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Use the filters below to find and compare flights from Mississippi to Roanoke that are best for you.

See travel insights to Roanoke from

How to get the cheapest flight ticket from Mississippi to Roanoke

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Roanoke?

What is the cheapest time of day to depart on your flight to Roanoke?

Our most recent data shows that the best time of day to fly to Roanoke is in the afternoon. Flights from Mississippi to Roanoke during this time can be as low as $447. In contrast, the most expensive time of day to depart to Roanoke is in the morning when prices are around $575.

What is the cheapest airline that flies from Mississippi to Roanoke?

Delta, American Airlines, and United Airlines are the most popular carriers operating from Mississippi to Roanoke

Cheap Mississippi to Roanoke flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Mississippi to Roanoke

Direct flights

When did momondo last update prices for flights from Mississippi to Roanoke Airport?

How many operators does momondo search for flights from Mississippi to Roanoke Airport?

How old do you have to be to fly from Mississippi to Roanoke Airport?

What documentation or ID do you need to fly to Roanoke Airport?

Traveling to a place near Roanoke?

Why use momondo?

Why should I use momondo to find a flight deal from Mississippi to Roanoke?

Can I find flights from Mississippi to Roanoke with flexible booking policies on momondo?

How can momondo help me find flights from Mississippi to Roanoke?

I’m not ready to book a flight from Mississippi to Roanoke right now. Can momondo alert me if prices change?

An easier way to manage your Roanoke trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Virginia