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Cheap flights from Minneapolis to South America from $144

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to South America departing on 1/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Minneapolis to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:30 am - 12:57 amMSP-MDE
17h 27m1 stop
Multiple Airlines Logo
3:14 pm - 12:00 pmMDE-MSP
21h 46m2 stops
$363Multiple Airlines
Find Deal
Sun, Nov 9 - Wed, Nov 12
Spirit Airlines Logo
1:05 pm - 12:57 amMSP-MDE
10h 52m2 stops
Spirit Airlines Logo
1:52 am - 12:00 pmMDE-MSP
11h 08m2 stops
$392Spirit Airlines
Find Deal
Fri, Nov 7 - Thu, Nov 13
LATAM Airlines Logo
5:10 am - 9:35 pmMSP-UIO
15h 25m1 stop
LATAM Airlines Logo
11:45 pm - 11:50 amUIO-MSP
13h 05m1 stop
$730LATAM Airlines
Find Deal
Mon, Feb 2 - Tue, Feb 10
LATAM Airlines Logo
12:50 pm - 5:17 amMSP-UIO
15h 27m1 stop
LATAM Airlines Logo
7:00 pm - 11:47 amUIO-MSP
17h 47m2 stops
$731LATAM Airlines
Find Deal
Sat, Feb 7 - Mon, Feb 16
American Airlines Logo
6:28 am - 11:33 pmMSP-UIO
16h 05m2 stops
American Airlines Logo
7:30 am - 9:07 pmUIO-MSP
14h 37m2 stops
$734American Airlines
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Wed, Feb 18 - Wed, Feb 25
Delta Logo
6:05 pm - 8:00 pmMSP-UIO
24h 55m1 stop
Delta Logo
11:45 pm - 10:30 amUIO-MSP
11h 45m1 stop
$735Delta
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Sun, Feb 22 - Thu, Mar 5
Delta Logo
6:05 pm - 8:00 pmMSP-UIO
24h 55m1 stop
Delta Logo
11:45 pm - 3:33 pmUIO-MSP
16h 48m1 stop
$741Delta
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Sun, Feb 15 - Tue, Feb 24
American Airlines Logo
6:00 am - 11:47 pmMSP-UIO
16h 47m1 stop
American Airlines Logo
7:04 am - 11:59 pmUIO-MSP
17h 55m1 stop
$750American Airlines
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Sat, Jan 31 - Sun, Feb 8
United Airlines Logo
8:00 am - 8:50 amMSP-SCL
21h 50m1 stop
United Airlines Logo
10:45 pm - 9:35 pmSCL-MSP
25h 50m2 stops
$999United Airlines
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Fri, Nov 21 - Fri, Nov 28
United Airlines Logo
6:36 pm - 7:15 amMSP-GRU
33h 39m1 stop
United Airlines Logo
9:45 pm - 10:25 amGRU-MSP
15h 40m1 stop
$1,008United Airlines
Find Deal
Sun, Nov 23 - Mon, Dec 1

Copa Airlines flights from Minneapolis to South America

Our best Copa Airlines deals on Minneapolis to South America flight tickets
Copa Airlines
Nov 19
MSP8:00 amMinneapolis St Paul
13h 55m
2 stops
BOG10:55 pmBogotá El Dorado
Nov 25
BOG6:08 pmBogotá El Dorado
26h 32m
2 stops
MSP7:40 pmMinneapolis St Paul
$544
Find similar
Copa Airlines
Nov 19
MSP9:55 amMinneapolis St Paul
22h 30m
2 stops
BOG9:25 amBogotá El Dorado
Nov 25
BOG4:45 amBogotá El Dorado
15h 55m
2 stops
MSP7:40 pmMinneapolis St Paul
$569
Find similar
Copa Airlines
Nov 19
MSP9:55 amMinneapolis St Paul
13h 10m
2 stops
BOG12:05 amBogotá El Dorado
Nov 27
BOG6:08 pmBogotá El Dorado
26h 32m
2 stops
MSP7:40 pmMinneapolis St Paul
$604
Find similar

Air Canada flights from Minneapolis to South America

Our best Air Canada deals on Minneapolis to South America flight tickets
Air Canada
Apr 13
MSP4:25 pmMinneapolis St Paul
14h 50m
1 stop
GRU9:15 amSao Paulo Guarulhos Intl
Apr 20
GRU9:00 pmSao Paulo Guarulhos Intl
20h 42m
2 stops
MSP3:42 pmMinneapolis St Paul
$694
Find similar
Air Canada
Nov 23
MSP12:00 pmMinneapolis St Paul
19h 35m
1 stop
GRU10:35 amSao Paulo Guarulhos Intl
Dec 2
GRU9:45 pmSao Paulo Guarulhos Intl
26h 34m
2 stops
MSP9:19 pmMinneapolis St Paul
$699
Find similar
Air Canada
Mar 3
MSP4:30 pmMinneapolis St Paul
16h 35m
1 stop
GIG12:05 pmRio de Janeiro–Galeão Intl
Mar 24
GIG3:55 pmRio de Janeiro–Galeão Intl
25h 54m
2 stops
MSP3:49 pmMinneapolis St Paul
$705
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Minneapolis to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Sun 11/9

6:30 am-12:57 am

1 stop17h 27m

Medellín Jose Maria Cordova Intl

Wed 11/12

3:14 pm-12:00 pm

2 stops21h 46m

$363

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Fri 11/7

1:05 pm-12:57 am

2 stops10h 52m

Medellín Jose Maria Cordova Intl

Thu 11/13

1:52 am-12:00 pm

2 stops11h 08m

$392

MinneapolisQuito

MSP - UIO

MSPUIO

Minneapolis St Paul

Mon 2/2

5:10 am-9:35 pm

1 stop15h 25m

Quito Mariscal Sucr

Tue 2/10

11:45 pm-11:50 am

1 stop13h 05m

$730

MinneapolisQuito

MSP - UIO

MSPUIO

Minneapolis St Paul

Sat 2/7

12:50 pm-5:17 am

1 stop15h 27m

Quito Mariscal Sucr

Mon 2/16

7:00 pm-11:47 am

2 stops17h 47m

$731

MinneapolisQuito

MSP - UIO

MSPUIO

Minneapolis St Paul

Wed 2/18

6:28 am-11:33 pm

2 stops16h 05m

Quito Mariscal Sucr

Wed 2/25

7:30 am-9:07 pm

2 stops14h 37m

$734

MinneapolisQuito

MSP - UIO

MSPUIO

Minneapolis St Paul

Sun 2/22

6:05 pm-8:00 pm

1 stop24h 55m

Quito Mariscal Sucr

Thu 3/5

11:45 pm-10:30 am

1 stop11h 45m

$735

MinneapolisQuito

MSP - UIO

MSPUIO

Minneapolis St Paul

Sun 2/15

6:05 pm-8:00 pm

1 stop24h 55m

Quito Mariscal Sucr

Tue 2/24

11:45 pm-3:33 pm

1 stop16h 48m

$741

MinneapolisQuito

MSP - UIO

MSPUIO

Minneapolis St Paul

Sat 1/31

6:00 am-11:47 pm

1 stop16h 47m

Quito Mariscal Sucr

Sun 2/8

7:04 am-11:59 pm

1 stop17h 55m

$750

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Fri 11/21

8:00 am-8:50 am

1 stop21h 50m

Santiago Arturo Merino Benitez

Fri 11/28

10:45 pm-9:35 pm

2 stops25h 50m

$999

MinneapolisSao Paulo

MSP - GRU

MSPGRU

Minneapolis St Paul

Sun 11/23

6:36 pm-7:15 am

1 stop33h 39m

Sao Paulo Guarulhos Intl

Mon 12/1

9:45 pm-10:25 am

1 stop15h 40m

$1,008

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Minneapolis to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Minneapolis to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $834. If you aren’t able to travel during the month of February, then book flights to South America from Minneapolis during January instead. Flights to South America in January, while not as cheap as those in February, still average around $839.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Minneapolis to South America is on a Monday when prices can be found for as low as $806. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Minneapolis to South America for around $953.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Minneapolis to South America flights are usually those with departure times at noon. Our users have found flights to South America at noon for as low as $703. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $915 on average. Flights to South America from Minneapolis in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $924 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Minneapolis for as low as $738 on momondo.

Can stopping save me money on Minneapolis to South America flights?

You could potentially save up to 28% on your flight if you consider stops on a Minneapolis to South America flight.

Cheap Minneapolis to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to South America

Direct flights

None
There are no direct flights from Minneapolis to South America. There are no popular flight routes from Minneapolis to South America.
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  • When did momondo last update prices for flights from Minneapolis St Paul Airport to South America?

    Prices for flights from Minneapolis St Paul Airport to South America are updated daily.

  • How many operators does momondo search for flights from Minneapolis St Paul Airport to South America?

  • How old do you have to be to fly from Minneapolis St Paul Airport to South America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Minneapolis to South America

Compare and see reviews for airlines that fly from Minneapolis to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $239Free CancellationRating
7.9
7,994 reviews
Search Delta flights
Sky Airlines PeruPriceFrom $292Free CancellationRating
0.0
0 reviews
Search Sky Airlines Peru flights
Spirit AirlinesPriceFrom $366Free CancellationRating
6.3
8,114 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $410Free CancellationRating
7.4
9,001 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $470Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
AviancaPriceFrom $536Free CancellationRating
6.6
2,468 reviews
Search Avianca flights
American AirlinesPriceFrom $574Free CancellationRating
7.2
11,032 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $628Free CancellationRating
7.5
1,871 reviews
Search LATAM Airlines flights
Air CanadaPriceFrom $773Free CancellationRating
7.1
10,371 reviews
Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to South America?

Finding the right flight to South America from Minneapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Minneapolis to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Minneapolis to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Minneapolis to South America?

momondo helps you find the best flight between Minneapolis and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Minneapolis to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Minneapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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Find better results for your trip to South America

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