What is the cheapest airline that flies from Minneapolis St Paul to South America?

Air Canada, American Airlines, and Azul are the most popular carriers operating from Minneapolis St Paul to South America

What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Minneapolis according to our data. Delta is the first choice among our users, with 39% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 9 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Minneapolis St Paul Airport to South America?

Prices for flights from Minneapolis St Paul Airport to South America are updated daily.

How many operators does momondo search for flights from Minneapolis St Paul Airport to South America?

As of February 2026, there are 9 operators available to choose from for flights from Minneapolis St Paul Airport to South America.

How old do you have to be to fly from Minneapolis St Paul Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$171 Cheap Flights from Minneapolis to South America in 2026

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Find the cheapest flights from Minneapolis to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:40 am - 12:16 am

MSP

MDE

17h 36m

1 stop

2:06 pm - 9:50 am

MDE

MSP

19h 44m

2 stops

$388Multiple Airlines

Mon, May 4 - Wed, May 13

9:49 am - 9:49 am

MSP

MDE

24h 00m

1 stop

10:51 am - 9:50 am

MDE

MSP

22h 59m

1 stop

$424Multiple Airlines

Mon, May 4 - Wed, May 13

7:48 am - 12:21 am

MSP

MDE

16h 33m

1 stop

1:11 am - 12:45 pm

MDE

MSP

35h 34m

2 stops

$434Multiple Airlines

Mon, Apr 13 - Sat, Apr 18

6:24 am - 12:16 am

MSP

MDE

17h 52m

1 stop

2:06 pm - 12:45 pm

MDE

MSP

22h 39m

2 stops

$437Multiple Airlines

Thu, Apr 16 - Wed, Apr 29

7:59 pm - 9:51 am

MSP

MDE

13h 52m

1 stop

10:51 am - 9:39 am

MDE

MSP

22h 48m

1 stop

$457Multiple Airlines

Wed, Apr 1 - Thu, Apr 30

3:53 pm - 11:55 am

MSP

BOG

20h 02m

2 stops

12:50 pm - 9:57 am

BOG

MSP

21h 07m

1 stop

$462Multiple Airlines

Wed, Apr 8 - Sun, Apr 12

1:00 pm - 11:55 am

MSP

BOG

22h 55m

1 stop

12:50 pm - 9:57 am

BOG

MSP

21h 07m

1 stop

$464Multiple Airlines

Wed, Apr 8 - Sun, Apr 12

7:59 pm - 9:51 am

MSP

MDE

13h 52m

1 stop

10:51 am - 9:39 am

MDE

MSP

22h 48m

1 stop

$466Multiple Airlines

Wed, Apr 1 - Thu, Apr 30

4:25 pm - 11:15 am

MSP

SCL

16h 50m

1 stop

7:55 pm - 9:19 pm

SCL

MSP

27h 24m

1 stop

$791Air Canada

Mon, Mar 9 - Mon, Mar 16

4:25 pm - 9:50 am

MSP

GRU

39h 25m

2 stops

9:00 pm - 8:40 pm

GRU

MSP

25h 40m

1 stop

$853Air Canada

Mon, Apr 27 - Mon, May 4

American Airlines flights from Minneapolis to South America

Our best American Airlines deals on Minneapolis to South America flight tickets

American Airlines

Jul 22

MSP8:00 amMinneapolis St Paul

15h 55m

2 stops

UIO11:55 pmQuito Mariscal Sucr

Aug 22

UIO6:09 amQuito Mariscal Sucr

17h 31m

2 stops

MSP11:40 pmMinneapolis St Paul

$775

American Airlines

May 17

MSP6:03 amMinneapolis St Paul

13h 54m

1 stop

UIO7:57 pmQuito Mariscal Sucr

Jun 1

UIO6:00 amQuito Mariscal Sucr

18h 22m

1 stop

MSP12:22 amMinneapolis St Paul

$796

American Airlines

May 17

MSP6:03 amMinneapolis St Paul

13h 54m

1 stop

UIO7:57 pmQuito Mariscal Sucr

Jun 1

UIO11:59 pmQuito Mariscal Sucr

17h 04m

2 stops

MSP5:03 pmMinneapolis St Paul

$800

United Airlines flights from Minneapolis to South America

Our best United Airlines deals on Minneapolis to South America flight tickets

United Airlines

Aug 11

MSP2:00 pmMinneapolis St Paul

9h 25m

1 stop

UIO11:25 pmQuito Mariscal Sucr

Aug 18

UIO7:25 amQuito Mariscal Sucr

15h 40m

1 stop

MSP11:05 pmMinneapolis St Paul

$762

United Airlines

Aug 11

MSP2:00 pmMinneapolis St Paul

9h 25m

1 stop

UIO11:25 pmQuito Mariscal Sucr

Aug 18

UIO7:25 amQuito Mariscal Sucr

13h 41m

2 stops

MSP9:06 pmMinneapolis St Paul

$767

United Airlines

Jul 22

MSP12:05 pmMinneapolis St Paul

11h 20m

1 stop

UIO11:25 pmQuito Mariscal Sucr

Aug 22

UIO7:25 amQuito Mariscal Sucr

15h 40m

1 stop

MSP11:05 pmMinneapolis St Paul

$771

momondo Fare Finder

Use the filters below to find and compare flights from Minneapolis to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Mon 5/4

6:40 am-12:16 am

1 stop17h 36m

Medellín Jose Maria Cordova Intl

Wed 5/13

2:06 pm-9:50 am

2 stops19h 44m

$388

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Mon 5/4

9:49 am-9:49 am

1 stop24h 00m

Medellín Jose Maria Cordova Intl

Wed 5/13

10:51 am-9:50 am

1 stop22h 59m

$424

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Mon 4/13

7:48 am-12:21 am

1 stop16h 33m

Medellín Jose Maria Cordova Intl

Sat 4/18

1:11 am-12:45 pm

2 stops35h 34m

$434

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Thu 4/16

6:24 am-12:16 am

1 stop17h 52m

Medellín Jose Maria Cordova Intl

Wed 4/29

2:06 pm-12:45 pm

2 stops22h 39m

$437

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Wed 4/1

7:59 pm-9:51 am

1 stop13h 52m

Medellín Jose Maria Cordova Intl

Thu 4/30

10:51 am-9:39 am

1 stop22h 48m

$457

MinneapolisBogotá

MSP - BOG

MSPBOG

Minneapolis St Paul

Wed 4/8

3:53 pm-11:55 am

2 stops20h 02m

Bogotá El Dorado

Sun 4/12

12:50 pm-9:57 am

1 stop21h 07m

$462

MinneapolisBogotá

MSP - BOG

MSPBOG

Minneapolis St Paul

Wed 4/8

1:00 pm-11:55 am

1 stop22h 55m

Bogotá El Dorado

Sun 4/12

12:50 pm-9:57 am

1 stop21h 07m

$464

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Wed 4/1

7:59 pm-9:51 am

1 stop13h 52m

Medellín Jose Maria Cordova Intl

Thu 4/30

10:51 am-9:39 am

1 stop22h 48m

$466

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 3/9

4:25 pm-11:15 am

1 stop16h 50m

Santiago Arturo Merino Benitez

Mon 3/16

7:55 pm-9:19 pm

1 stop27h 24m

$791

MinneapolisSao Paulo

MSP - GRU

MSPGRU

Minneapolis St Paul

Mon 4/27

4:25 pm-9:50 am

2 stops39h 25m

Sao Paulo Guarulhos Intl

Mon 5/4

9:00 pm-8:40 pm

1 stop25h 40m

$853

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Minneapolis to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Minneapolis to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $774. If you aren’t able to travel during the month of February, then book flights to South America from Minneapolis during September instead. Flights to South America in September, while not as cheap as those in February, still average around $854.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $915 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Minneapolis for as low as $662 on momondo.

Can stopping save me money on Minneapolis to South America flights?

You could potentially save up to 35% on your flight if you consider stops on a Minneapolis to South America flight.

Cheap Minneapolis to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to South America

Fastest flight time	7h 15m
Direct flights	None

The fastest flight from Minneapolis to South America takes 7h 15m

There are no direct flights from Minneapolis to South America. There are no popular flight routes from Minneapolis to South America.

Search flight deals

When did momondo last update prices for flights from Minneapolis St Paul Airport to South America?
Prices for flights from Minneapolis St Paul Airport to South America are updated daily.
How many operators does momondo search for flights from Minneapolis St Paul Airport to South America?
As of February 2026, there are 9 operators available to choose from for flights from Minneapolis St Paul Airport to South America.
How old do you have to be to fly from Minneapolis St Paul Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Minneapolis to South America

Compare and see reviews for airlines that fly from Minneapolis to South America with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $247	Free Cancellation	Rating 7.9 8,240 reviews	Search Delta flights
Sky Airlines Peru	PriceFrom $292	Free Cancellation	Rating 0.0 0 reviews	Search Sky Airlines Peru flights
United Airlines	PriceFrom $392	Free Cancellation	Rating 7.4 9,363 reviews	Search United Airlines flights
Spirit Airlines	PriceFrom $424	Free Cancellation	Rating 6.3 8,494 reviews	Search Spirit Airlines flights
Copa Airlines	PriceFrom $470	Free Cancellation	Rating 7.5 1,557 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $518	Free Cancellation	Rating 7.1 11,366 reviews	Search American Airlines flights
Avianca	PriceFrom $536	Free Cancellation	Rating 6.5 2,495 reviews	Search Avianca flights
LATAM Airlines	PriceFrom $603	Free Cancellation	Rating 7.5 1,924 reviews	Search LATAM Airlines flights
Air Canada	PriceFrom $698	Free Cancellation	Rating 7.1 10,757 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to South America?

Finding the right flight to South America from Minneapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Minneapolis to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Minneapolis to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Minneapolis to South America?

momondo helps you find the best flight between Minneapolis and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Minneapolis to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Minneapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.