What is the cheapest airline that flies from Minneapolis St Paul to South America?

Avianca, LATAM Airlines, and American Airlines are the most popular carriers operating from Minneapolis St Paul to South America

What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Minneapolis according to our data. Delta is the first choice among our users, with 39% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 9 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Minneapolis St Paul Airport to South America?

Prices for flights from Minneapolis St Paul Airport to South America are updated daily.

How many operators does momondo search for flights from Minneapolis St Paul Airport to South America?

As of March 2026, there are 10 operators available to choose from for flights from Minneapolis St Paul Airport to South America.

How old do you have to be to fly from Minneapolis St Paul Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$207 Cheap Flights from Minneapolis to South America in 2026

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Find the cheapest flights from Minneapolis to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

10:34 am - 1:00 pm

MSP

MDE

26h 26m

1 stop

1:55 pm - 9:50 am

MDE

MSP

19h 55m

1 stop

$441Multiple Airlines

Thu, Apr 23 - Fri, May 1

10:45 am - 1:00 pm

MSP

MDE

26h 15m

1 stop

1:55 pm - 8:54 am

MDE

MSP

18h 59m

1 stop

$453Multiple Airlines

Sat, Apr 25 - Sun, May 3

8:36 am - 11:04 pm

MSP

GYE

14h 28m

2 stops

11:59 pm - 3:01 pm

GYE

MSP

15h 02m

2 stops

$455Multiple Airlines

Thu, Apr 16 - Thu, Apr 23

5:15 am - 6:59 pm

MSP

UIO

13h 44m

1 stop

6:50 pm - 10:16 am

UIO

MSP

15h 26m

1 stop

$782LATAM Airlines

Tue, Sep 1 - Tue, Sep 8

12:00 pm - 9:15 am

MSP

GRU

19h 15m

1 stop

9:45 pm - 3:43 pm

GRU

MSP

19h 58m

1 stop

$814Air Canada

Fri, Apr 24 - Mon, Apr 27

1:05 pm - 2:30 pm

MSP

EZE

47h 25m

3 stops

4:35 pm - 12:10 pm

EZE

MSP

21h 35m

2 stops

$1,047Air Canada

Sat, May 9 - Sat, May 16

6:30 pm - 4:00 pm

MSP

AEP

19h 30m

2 stops

8:05 pm - 11:39 am

AEP

MSP

17h 34m

2 stops

$1,209LATAM Airlines

Tue, Aug 11 - Tue, Aug 18

2:59 pm - 9:40 am

MSP

AEP

16h 41m

2 stops

3:45 pm - 10:10 am

AEP

MSP

20h 25m

2 stops

$1,247Delta

Wed, May 6 - Wed, May 27

7:35 am - 4:45 pm

MSP

SDU

31h 10m

2 stops

1:45 pm - 10:28 am

SDU

MSP

22h 43m

2 stops

$1,344United Airlines

Tue, Jul 28 - Tue, Aug 4

12:05 pm - 4:45 pm

MSP

SDU

26h 40m

2 stops

1:45 pm - 10:28 am

SDU

MSP

22h 43m

2 stops

$1,346United Airlines

Tue, Jul 28 - Fri, Aug 7

American Airlines flights from Minneapolis to South America

Our best American Airlines deals on Minneapolis to South America flight tickets

American Airlines

Jun 3

MSP6:24 amMinneapolis St Paul

17h 26m

1 stop

MDE11:50 pmMedellín Jose Maria Cordova Intl

Jun 11

MDE6:00 amMedellín Jose Maria Cordova Intl

18h 22m

1 stop

MSP12:22 amMinneapolis St Paul

$660

American Airlines

Jun 3

MSP8:00 amMinneapolis St Paul

15h 50m

2 stops

MDE11:50 pmMedellín Jose Maria Cordova Intl

Jun 11

MDE1:53 pmMedellín Jose Maria Cordova Intl

10h 29m

1 stop

MSP12:22 amMinneapolis St Paul

$665

American Airlines

Jun 8

MSP4:15 pmMinneapolis St Paul

21h 16m

2 stops

GYE1:31 pmGuayaquil Jose Joaquin de Olmedo

Jun 15

GYE2:31 pmGuayaquil Jose Joaquin de Olmedo

22h 56m

2 stops

MSP1:27 pmMinneapolis St Paul

$672

Copa Airlines flights from Minneapolis to South America

Our best Copa Airlines deals on Minneapolis to South America flight tickets

Copa Airlines

Jun 3

MSP9:52 amMinneapolis St Paul

22h 23m

2 stops

MDE8:15 amMedellín Jose Maria Cordova Intl

Jun 11

MDE4:30 pmMedellín Jose Maria Cordova Intl

16h 16m

2 stops

MSP8:46 amMinneapolis St Paul

$664

Copa Airlines

Jul 11

MSP6:50 pmMinneapolis St Paul

25h 45m

2 stops

MDE8:35 pmMedellín Jose Maria Cordova Intl

Jul 18

MDE3:10 pmMedellín Jose Maria Cordova Intl

19h 16m

2 stops

MSP10:26 amMinneapolis St Paul

$676

Copa Airlines

Jul 23

MSP9:52 amMinneapolis St Paul

22h 23m

2 stops

MDE8:15 amMedellín Jose Maria Cordova Intl

Jul 27

MDE3:10 pmMedellín Jose Maria Cordova Intl

17h 36m

2 stops

MSP8:46 amMinneapolis St Paul

$688

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Thu 4/23

10:34 am-1:00 pm

1 stop26h 26m

Medellín Jose Maria Cordova Intl

Fri 5/1

1:55 pm-9:50 am

1 stop19h 55m

$441

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Sat 4/25

10:45 am-1:00 pm

1 stop26h 15m

Medellín Jose Maria Cordova Intl

Sun 5/3

1:55 pm-8:54 am

1 stop18h 59m

$453

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

Thu 4/16

8:36 am-11:04 pm

2 stops14h 28m

Guayaquil Jose Joaquin de Olmedo

Thu 4/23

11:59 pm-3:01 pm

2 stops15h 02m

$455

Quickest round-trip

MinneapolisQuito

MSP - UIO

MSPUIO

Minneapolis St Paul

Tue 9/1

5:15 am-6:59 pm

1 stop13h 44m

Quito Mariscal Sucr

Tue 9/8

6:50 pm-10:16 am

1 stop15h 26m

$782

MinneapolisSao Paulo

MSP - GRU

MSPGRU

Minneapolis St Paul

Fri 4/24

12:00 pm-9:15 am

1 stop19h 15m

Sao Paulo Guarulhos Intl

Mon 4/27

9:45 pm-3:43 pm

1 stop19h 58m

$814

MinneapolisBuenos Aires

MSP - EZE

MSPEZE

Minneapolis St Paul

Sat 5/9

1:05 pm-2:30 pm

3 stops47h 25m

Buenos Aires Ministro Pistarini

Sat 5/16

4:35 pm-12:10 pm

2 stops21h 35m

$1,047

MinneapolisBuenos Aires

MSP - AEP

MSPAEP

Minneapolis St Paul

Tue 8/11

6:30 pm-4:00 pm

2 stops19h 30m

Buenos Aires Jorge Newbery

Tue 8/18

8:05 pm-11:39 am

2 stops17h 34m

$1,209

MinneapolisBuenos Aires

MSP - AEP

MSPAEP

Minneapolis St Paul

Wed 5/6

2:59 pm-9:40 am

2 stops16h 41m

Buenos Aires Jorge Newbery

Wed 5/27

3:45 pm-10:10 am

2 stops20h 25m

$1,247

MinneapolisRio de Janeiro

MSP - SDU

MSPSDU

Minneapolis St Paul

Tue 7/28

7:35 am-4:45 pm

2 stops31h 10m

Rio de Janeiro Santos Dumont

Tue 8/4

1:45 pm-10:28 am

2 stops22h 43m

$1,344

MinneapolisRio de Janeiro

MSP - SDU

MSPSDU

Minneapolis St Paul

Tue 7/28

12:05 pm-4:45 pm

2 stops26h 40m

Rio de Janeiro Santos Dumont

Fri 8/7

1:45 pm-10:28 am

2 stops22h 43m

$1,346

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Minneapolis to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Minneapolis to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $774. If you aren’t able to travel during the month of February, then book flights to South America from Minneapolis during November instead. Flights to South America in November, while not as cheap as those in February, still average around $871.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $907 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Minneapolis for as low as $648 on momondo.

Can stopping save me money on Minneapolis to South America flights?

You could potentially save up to 40% on your flight if you consider stops on a Minneapolis to South America flight.

Cheap Minneapolis to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to South America

Fastest flight time	8h 00m
Direct flights	None

The fastest flight from Minneapolis to South America takes 8h 00m

There are no direct flights from Minneapolis to South America. There are no popular flight routes from Minneapolis to South America.

Search flight deals

When did momondo last update prices for flights from Minneapolis St Paul Airport to South America?
Prices for flights from Minneapolis St Paul Airport to South America are updated daily.
How many operators does momondo search for flights from Minneapolis St Paul Airport to South America?
As of March 2026, there are 10 operators available to choose from for flights from Minneapolis St Paul Airport to South America.
How old do you have to be to fly from Minneapolis St Paul Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Minneapolis to South America

Compare and see reviews for airlines that fly from Minneapolis to South America with momondo

Airline	Rating	Free Cancellation	Price
Sun Country Air	PriceFrom $166	Free Cancellation	Rating 6.8 341 reviews	Search Sun Country Air flights
Delta	PriceFrom $247	Free Cancellation	Rating 7.9 8,293 reviews	Search Delta flights
Sky Airlines Peru	PriceFrom $292	Free Cancellation	Rating 0.0 0 reviews	Search Sky Airlines Peru flights
United Airlines	PriceFrom $392	Free Cancellation	Rating 7.4 9,439 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $470	Free Cancellation	Rating 7.5 1,571 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $518	Free Cancellation	Rating 7.1 11,473 reviews	Search American Airlines flights
Avianca	PriceFrom $536	Free Cancellation	Rating 6.5 2,500 reviews	Search Avianca flights
LATAM Airlines	PriceFrom $603	Free Cancellation	Rating 7.4 1,915 reviews	Search LATAM Airlines flights
Air Canada	PriceFrom $698	Free Cancellation	Rating 7.1 10,815 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to South America?

Finding the right flight to South America from Minneapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Minneapolis to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Minneapolis to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Minneapolis to South America?

momondo helps you find the best flight between Minneapolis and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Minneapolis to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Minneapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.