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Cheap flights from Minneapolis to South America from $167

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to South America departing on 1/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:36 am - 1:57 pmMSP-MDE
28h 21m3 stops
Multiple Airlines Logo
2:25 am - 3:06 pmMDE-MSP
13h 41m1 stop
$443Multiple Airlines
Find Deal
jue., dic. 11 - mié., dic. 17
Multiple Airlines Logo
1:55 pm - 12:56 amMSP-MDE
10h 01m2 stops
Multiple Airlines Logo
11:50 am - 10:17 pmMDE-MSP
11h 27m1 stop
$453Multiple Airlines
Find Deal
vie., nov. 28 - lun., dic. 29
United Airlines Logo
2:12 pm - 8:50 amMSP-SCL
15h 38m1 stop
United Airlines Logo
10:45 pm - 1:20 pmSCL-MSP
17h 35m1 stop
$504United Airlines
Find Deal
vie., dic. 5 - vie., dic. 12
United Airlines Logo
7:40 am - 8:50 amMSP-SCL
22h 10m1 stop
United Airlines Logo
10:45 pm - 8:44 amSCL-MSP
36h 59m2 stops
$509United Airlines
Find Deal
dom., dic. 7 - dom., dic. 14
American Airlines Logo
9:57 am - 8:15 amMSP-SCL
19h 18m1 stop
American Airlines Logo
10:30 pm - 2:11 pmSCL-MSP
18h 41m1 stop
$514American Airlines
Find Deal
lun., feb. 2 - mié., feb. 11
American Airlines Logo
11:05 am - 9:00 amMSP-SCL
18h 55m2 stops
American Airlines Logo
10:30 pm - 4:38 pmSCL-MSP
21h 08m2 stops
$519American Airlines
Find Deal
lun., feb. 2 - mié., feb. 11
LATAM Airlines Logo
5:10 am - 2:17 pmMSP-CTG
8h 07m1 stop
LATAM Airlines Logo
3:30 pm - 9:16 amCTG-MSP
18h 46m1 stop
$611LATAM Airlines
Find Deal
mié., feb. 4 - mié., feb. 25
Delta Logo
5:10 am - 2:17 pmMSP-CTG
8h 07m1 stop
Delta Logo
4:35 am - 6:45 pmCTG-MSP
15h 10m2 stops
$614Delta
Find Deal
mié., feb. 4 - mar., feb. 24
Delta Logo
7:45 pm - 7:20 amMSP-GYE
10h 35m1 stop
Delta Logo
4:30 pm - 10:18 amGYE-MSP
18h 48m1 stop
$645Delta
Find Deal
mar., ene. 20 - mar., ene. 27
LATAM Airlines Logo
9:00 am - 6:01 amMSP-CTG
20h 01m2 stops
LATAM Airlines Logo
3:30 pm - 9:16 amCTG-MSP
18h 46m1 stop
$672LATAM Airlines
Find Deal
jue., feb. 26 - mar., mar. 3

Delta flights from Minneapolis to South America

Our best Delta deals on Minneapolis to South America flight tickets
Delta
Feb 4
MSP5:10 amMinneapolis St Paul
8h 07m
1 stop
CTG2:17 pmCartagena Rafael Nunez
Feb 24
CTG4:35 amCartagena Rafael Nunez
15h 10m
2 stops
MSP6:45 pmMinneapolis St Paul
$614
Find similar
Delta
Jan 20
MSP7:45 pmMinneapolis St Paul
10h 35m
1 stop
GYE7:20 amGuayaquil Jose Joaquin de Olmedo
Jan 27
GYE4:30 pmGuayaquil Jose Joaquin de Olmedo
18h 48m
1 stop
MSP10:18 amMinneapolis St Paul
$645
Find similar
Delta
Jan 20
MSP12:45 pmMinneapolis St Paul
17h 35m
2 stops
GYE7:20 amGuayaquil Jose Joaquin de Olmedo
Jan 27
GYE4:30 pmGuayaquil Jose Joaquin de Olmedo
22h 16m
2 stops
MSP1:46 pmMinneapolis St Paul
$650
Find similar

Copa Airlines flights from Minneapolis to South America

Our best Copa Airlines deals on Minneapolis to South America flight tickets
Copa Airlines
Dec 9
MSP8:00 amMinneapolis St Paul
24h 51m
2 stops
MDE9:51 amMedellín Jose Maria Cordova Intl
Dec 16
MDE5:00 amMedellín Jose Maria Cordova Intl
15h 40m
2 stops
MSP7:40 pmMinneapolis St Paul
$630
Find similar
Copa Airlines
Nov 20
MSP9:55 amMinneapolis St Paul
23h 15m
2 stops
BOG10:10 amBogotá El Dorado
Nov 24
BOG4:45 amBogotá El Dorado
13h 45m
2 stops
MSP5:30 pmMinneapolis St Paul
$658
Find similar
Copa Airlines
Nov 19
MSP8:00 amMinneapolis St Paul
25h 10m
2 stops
BOG10:10 amBogotá El Dorado
Nov 26
BOG4:45 amBogotá El Dorado
31h 02m
2 stops
MSP10:47 amMinneapolis St Paul
$763
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 10, 2025.
Use the filters below to find and compare flights from Minneapolis to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

jue. 12/11

8:36 am-1:57 pm

3 stops28h 21m

Medellín Jose Maria Cordova Intl

mié. 12/17

2:25 am-3:06 pm

1 stop13h 41m

$443

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

vie. 11/28

1:55 pm-12:56 am

2 stops10h 01m

Medellín Jose Maria Cordova Intl

lun. 12/29

11:50 am-10:17 pm

1 stop11h 27m

$453

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

vie. 12/5

2:12 pm-8:50 am

1 stop15h 38m

Santiago Arturo Merino Benitez

vie. 12/12

10:45 pm-1:20 pm

1 stop17h 35m

$504

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

dom. 12/7

7:40 am-8:50 am

1 stop22h 10m

Santiago Arturo Merino Benitez

dom. 12/14

10:45 pm-8:44 am

2 stops36h 59m

$509

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

lun. 2/2

9:57 am-8:15 am

1 stop19h 18m

Santiago Arturo Merino Benitez

mié. 2/11

10:30 pm-2:11 pm

1 stop18h 41m

$514

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

lun. 2/2

11:05 am-9:00 am

2 stops18h 55m

Santiago Arturo Merino Benitez

mié. 2/11

10:30 pm-4:38 pm

2 stops21h 08m

$519

MinneapolisCartagena

MSP - CTG

MSPCTG

Minneapolis St Paul

mié. 2/4

5:10 am-2:17 pm

1 stop8h 07m

Cartagena Rafael Nunez

mié. 2/25

3:30 pm-9:16 am

1 stop18h 46m

$611

MinneapolisCartagena

MSP - CTG

MSPCTG

Minneapolis St Paul

mié. 2/4

5:10 am-2:17 pm

1 stop8h 07m

Cartagena Rafael Nunez

mar. 2/24

4:35 am-6:45 pm

2 stops15h 10m

$614

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

mar. 1/20

7:45 pm-7:20 am

1 stop10h 35m

Guayaquil Jose Joaquin de Olmedo

mar. 1/27

4:30 pm-10:18 am

1 stop18h 48m

$645

MinneapolisCartagena

MSP - CTG

MSPCTG

Minneapolis St Paul

jue. 2/26

9:00 am-6:01 am

2 stops20h 01m

Cartagena Rafael Nunez

mar. 3/3

3:30 pm-9:16 am

1 stop18h 46m

$672

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Minneapolis to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Minneapolis to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $831. If you aren’t able to travel during the month of February, then book flights to South America from Minneapolis during January instead. Flights to South America in January, while not as cheap as those in February, still average around $839.

What is the cheapest day to depart on your flight to South America?

The cheapest day to depart from Minneapolis to South America is on a Monday when prices can be found for as low as $806. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Minneapolis to South America for around $953.

What is the cheapest time of day to depart on your flight to South America?

Our data shows that the cheapest Minneapolis to South America flights are usually those with departure times at noon. Our users have found flights to South America at noon for as low as $703. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $915 on average. Flights to South America from Minneapolis in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $912 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Minneapolis for as low as $696 on momondo.

Can stopping save me money on Minneapolis to South America flights?

You could potentially save up to 28% on your flight if you consider stops on a Minneapolis to South America flight.

Cheap Minneapolis to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to South America

Direct flights

None
There are no direct flights from Minneapolis to South America. There are no popular flight routes from Minneapolis to South America.
Search flight deals

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to South America?

    Prices for flights from Minneapolis St Paul Airport to South America are updated daily.

  • How many operators does momondo search for flights from Minneapolis St Paul Airport to South America?

  • How old do you have to be to fly from Minneapolis St Paul Airport to South America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Minneapolis to South America

Compare and see reviews for airlines that fly from Minneapolis to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $239Free CancellationRating
7.9
8,006 reviews
Search Delta flights
Sky Airlines PeruPriceFrom $292Free CancellationRating
0.0
0 reviews
Search Sky Airlines Peru flights
Spirit AirlinesPriceFrom $366Free CancellationRating
6.3
8,136 reviews
Search Spirit Airlines flights
United AirlinesPriceFrom $527Free CancellationRating
7.4
9,012 reviews
Search United Airlines flights
AviancaPriceFrom $536Free CancellationRating
6.6
2,473 reviews
Search Avianca flights
American AirlinesPriceFrom $574Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $628Free CancellationRating
7.5
1,872 reviews
Search LATAM Airlines flights
Copa AirlinesPriceFrom $630Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
Air CanadaPriceFrom $698Free CancellationRating
7.1
10,437 reviews
Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to South America?

Finding the right flight to South America from Minneapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Minneapolis to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Minneapolis to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Minneapolis to South America?

momondo helps you find the best flight between Minneapolis and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Minneapolis to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Minneapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
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1 adult
mié. 12/10
mié. 12/17
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Find better results for your trip to South America

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Popular flights according to clicks in the last 7 days on momondo
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