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Cheap flights from Minneapolis to South America from $140

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to South America departing on 2/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Minneapolis to South America

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:17 pm - 1:55 pm
MSP
-
MDE
16h 38m
1 stop
Multiple Airlines Logo
1:52 pm - 11:57 pm
MDE
-
MSP
34h 05m
2 stops
$395Multiple Airlines
Sun, Mar 1 - Tue, Mar 17
Multiple Airlines Logo
11:26 am - 1:55 pm
MSP
-
MDE
25h 29m
1 stop
Multiple Airlines Logo
1:52 pm - 11:57 pm
MDE
-
MSP
34h 05m
2 stops
$425Multiple Airlines
Mon, Mar 2 - Tue, Mar 17
Air Canada Logo
1:10 pm - 9:50 am
MSP
-
GRU
18h 40m
1 stop
Air Canada Logo
9:00 pm - 8:40 pm
GRU
-
MSP
25h 40m
1 stop
$700Air Canada
Tue, May 5 - Wed, May 13
Air Canada Logo
1:10 pm - 9:50 am
MSP
-
GRU
18h 40m
1 stop
Air Canada Logo
9:35 pm - 12:20 pm
GRU
-
MSP
16h 45m
1 stop
$705Air Canada
Tue, May 5 - Tue, May 12
United Airlines Logo
12:05 pm - 5:00 am
MSP
-
UIO
16h 55m
1 stop
United Airlines Logo
12:35 am - 5:12 pm
UIO
-
MSP
16h 37m
1 stop
$741United Airlines
Thu, Jul 23 - Wed, Aug 5
United Airlines Logo
12:05 pm - 5:00 am
MSP
-
UIO
16h 55m
1 stop
United Airlines Logo
7:25 am - 12:27 am
UIO
-
MSP
17h 02m
2 stops
$745United Airlines
Thu, Jul 23 - Tue, Aug 4
LATAM Airlines Logo
6:12 pm - 9:45 am
MSP
-
EZE
13h 33m
1 stop
LATAM Airlines Logo
2:25 am - 10:15 am
EZE
-
MSP
33h 50m
2 stops
$1,201LATAM Airlines
Mon, Apr 6 - Sun, Apr 19
LATAM Airlines Logo
2:56 pm - 9:45 am
MSP
-
EZE
16h 49m
1 stop
LATAM Airlines Logo
8:10 pm - 9:08 am
EZE
-
MSP
14h 58m
1 stop
$1,212LATAM Airlines
Mon, Apr 6 - Mon, Apr 20
American Airlines Logo
3:08 pm - 8:20 am
MSP
-
EZE
15h 12m
1 stop
American Airlines Logo
10:25 pm - 2:16 pm
EZE
-
MSP
17h 51m
1 stop
$1,217American Airlines
Thu, Mar 19 - Tue, Mar 24
American Airlines Logo
10:47 am - 7:10 am
MSP
-
EZE
18h 23m
2 stops
American Airlines Logo
8:35 pm - 1:08 pm
EZE
-
MSP
18h 33m
2 stops
$1,221American Airlines
Thu, Mar 19 - Tue, Mar 24

Copa Airlines flights from Minneapolis to South America

Our best Copa Airlines deals on Minneapolis to South America flight tickets
Copa Airlines
Jul 21
MSP11:23 amMinneapolis St Paul
22h 06m
2 stops
BOG9:29 amBogotá El Dorado
Aug 15
BOG4:59 amBogotá El Dorado
14h 28m
2 stops
MSP7:27 pmMinneapolis St Paul
$701
Copa Airlines
Jul 25
MSP11:23 amMinneapolis St Paul
12h 59m
2 stops
BOG12:22 amBogotá El Dorado
Aug 15
BOG4:59 amBogotá El Dorado
14h 28m
2 stops
MSP7:27 pmMinneapolis St Paul
$711
Copa Airlines
Feb 4
MSP11:20 amMinneapolis St Paul
12h 10m
2 stops
UIO12:30 amQuito Mariscal Sucr
Feb 9
UIO1:35 amQuito Mariscal Sucr
13h 54m
2 stops
MSP2:29 pmMinneapolis St Paul
$1,212

American Airlines flights from Minneapolis to South America

Our best American Airlines deals on Minneapolis to South America flight tickets
American Airlines
Mar 28
MSP5:05 pmMinneapolis St Paul
19h 26m
2 stops
CTG12:31 pmCartagena Rafael Nunez
Apr 7
CTG1:25 pmCartagena Rafael Nunez
20h 29m
2 stops
MSP9:54 amMinneapolis St Paul
$639
American Airlines
Aug 1
MSP6:00 amMinneapolis St Paul
15h 17m
1 stop
BOG9:17 pmBogotá El Dorado
Aug 14
BOG12:25 amBogotá El Dorado
19h 43m
1 stop
MSP8:08 pmMinneapolis St Paul
$660
American Airlines
Aug 1
MSP6:00 amMinneapolis St Paul
15h 17m
1 stop
BOG9:17 pmBogotá El Dorado
Aug 20
BOG6:30 amBogotá El Dorado
16h 25m
1 stop
MSP10:55 pmMinneapolis St Paul
$663

momondo Fare Finder

 
Customize your flight search to find flights from Minneapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Minneapolis to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Sun 3/1

8:17 pm-1:55 pm

1 stop16h 38m

Medellín Jose Maria Cordova Intl

Tue 3/17

1:52 pm-11:57 pm

2 stops34h 05m

$395

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Mon 3/2

11:26 am-1:55 pm

1 stop25h 29m

Medellín Jose Maria Cordova Intl

Tue 3/17

1:52 pm-11:57 pm

2 stops34h 05m

$425

MinneapolisSao Paulo

MSP - GRU

MSPGRU

Minneapolis St Paul

Tue 5/5

1:10 pm-9:50 am

1 stop18h 40m

Sao Paulo Guarulhos Intl

Wed 5/13

9:00 pm-8:40 pm

1 stop25h 40m

$700

MinneapolisSao Paulo

MSP - GRU

MSPGRU

Minneapolis St Paul

Tue 5/5

1:10 pm-9:50 am

1 stop18h 40m

Sao Paulo Guarulhos Intl

Tue 5/12

9:35 pm-12:20 pm

1 stop16h 45m

$705

MinneapolisQuito

MSP - UIO

MSPUIO

Minneapolis St Paul

Thu 7/23

12:05 pm-5:00 am

1 stop16h 55m

Quito Mariscal Sucr

Wed 8/5

12:35 am-5:12 pm

1 stop16h 37m

$741

MinneapolisQuito

MSP - UIO

MSPUIO

Minneapolis St Paul

Thu 7/23

12:05 pm-5:00 am

1 stop16h 55m

Quito Mariscal Sucr

Tue 8/4

7:25 am-12:27 am

2 stops17h 02m

$745

MinneapolisBuenos Aires

MSP - EZE

MSPEZE

Minneapolis St Paul

Mon 4/6

6:12 pm-9:45 am

1 stop13h 33m

Buenos Aires Ministro Pistarini

Sun 4/19

2:25 am-10:15 am

2 stops33h 50m

$1,201

MinneapolisBuenos Aires

MSP - EZE

MSPEZE

Minneapolis St Paul

Mon 4/6

2:56 pm-9:45 am

1 stop16h 49m

Buenos Aires Ministro Pistarini

Mon 4/20

8:10 pm-9:08 am

1 stop14h 58m

$1,212

MinneapolisBuenos Aires

MSP - EZE

MSPEZE

Minneapolis St Paul

Thu 3/19

3:08 pm-8:20 am

1 stop15h 12m

Buenos Aires Ministro Pistarini

Tue 3/24

10:25 pm-2:16 pm

1 stop17h 51m

$1,217

MinneapolisBuenos Aires

MSP - EZE

MSPEZE

Minneapolis St Paul

Thu 3/19

10:47 am-7:10 am

2 stops18h 23m

Buenos Aires Ministro Pistarini

Tue 3/24

8:35 pm-1:08 pm

2 stops18h 33m

$1,221

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Minneapolis to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Minneapolis to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $813. If you aren’t able to travel during the month of February, then book flights to South America from Minneapolis during September instead. Flights to South America in September, while not as cheap as those in February, still average around $854.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $920 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Minneapolis for as low as $663 on momondo.

Can stopping save me money on Minneapolis to South America flights?

You could potentially save up to 42% on your flight if you consider stops on a Minneapolis to South America flight.

Cheap Minneapolis to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to South America

Fastest flight time

8h 25m

Direct flights

None
The fastest flight from Minneapolis to South America takes 8h 25m
There are no direct flights from Minneapolis to South America. There are no popular flight routes from Minneapolis to South America.
Search flight deals

  • When did momondo last update prices for flights from Minneapolis St Paul Airport to South America?

    Prices for flights from Minneapolis St Paul Airport to South America are updated daily.

  • How many operators does momondo search for flights from Minneapolis St Paul Airport to South America?

  • How old do you have to be to fly from Minneapolis St Paul Airport to South America?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to South America.

  • What documentation or ID do you need to fly to South America?

    The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Minneapolis to South America

Compare and see reviews for airlines that fly from Minneapolis to South America with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $247Free CancellationRating
7.9
8,139 reviews
Search Delta flights
Sky Airlines PeruPriceFrom $292Free CancellationRating
0.0
0 reviews
Search Sky Airlines Peru flights
United AirlinesPriceFrom $392Free CancellationRating
7.4
9,236 reviews
Search United Airlines flights
LATAM AirlinesPriceFrom $392Free CancellationRating
7.5
1,918 reviews
Search LATAM Airlines flights
Spirit AirlinesPriceFrom $424Free CancellationRating
6.3
8,407 reviews
Search Spirit Airlines flights
Copa AirlinesPriceFrom $470Free CancellationRating
7.5
1,556 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $518Free CancellationRating
7.2
11,217 reviews
Search American Airlines flights
AviancaPriceFrom $536Free CancellationRating
6.5
2,498 reviews
Search Avianca flights
Air CanadaPriceFrom $698Free CancellationRating
7.1
10,685 reviews
Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to South America?

Finding the right flight to South America from Minneapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Minneapolis to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Minneapolis to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Minneapolis to South America?

momondo helps you find the best flight between Minneapolis and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Minneapolis to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Minneapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your South America trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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Find better results for your trip to South America

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Popular flights according to clicks in the last 7 days on momondo
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Flights to Califrom $187