What airlines fly to South America?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to South America from Minneapolis according to our data. Delta is the first choice among our users, with 38% of people opting to fly with this airline when traveling to South America. Keep in mind that there are 9 different airlines that fly to South America on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Minneapolis St Paul to South America?

Avianca, United Airlines, and American Airlines are the most popular carriers operating from Minneapolis St Paul to South America

When did momondo last update prices for flights from Minneapolis St Paul Airport to South America?

Prices for flights from Minneapolis St Paul Airport to South America are updated daily.

How many operators does momondo search for flights from Minneapolis St Paul Airport to South America?

As of March 2026, there are 8 operators available to choose from for flights from Minneapolis St Paul Airport to South America.

How old do you have to be to fly from Minneapolis St Paul Airport to South America?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to South America.

What documentation or ID do you need to fly to South America?

The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$172 Cheap Flights from Minneapolis to South America in 2026

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Find the cheapest flights from Minneapolis to South America

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:54 am - 9:51 am

MSP

MDE

25h 57m

1 stop

1:55 pm - 9:39 am

MDE

MSP

19h 44m

1 stop

$434Multiple Airlines

Sun, Apr 12 - Wed, Apr 22

6:36 am - 1:22 pm

MSP

MDE

30h 46m

1 stop

2:06 pm - 11:04 am

MDE

MSP

20h 58m

2 stops

$436Multiple Airlines

Sun, Apr 12 - Thu, Apr 16

10:34 am - 1:00 pm

MSP

MDE

26h 26m

1 stop

1:55 pm - 8:54 am

MDE

MSP

18h 59m

1 stop

$457Multiple Airlines

Thu, Apr 30 - Sun, May 3

1:05 pm - 12:50 am

MSP

LIM

35h 45m

2 stops

1:40 am - 8:40 pm

LIM

MSP

43h 00m

2 stops

$624Avianca

Fri, May 8 - Tue, May 19

1:10 pm - 8:55 am

MSP

GYE

19h 45m

2 stops

10:05 am - 8:38 pm

GYE

MSP

34h 33m

2 stops

$647Avianca

Mon, Sep 14 - Wed, Sep 30

6:05 pm - 11:10 am

MSP

CUZ

17h 05m

2 stops

7:30 am - 12:21 am

CUZ

MSP

16h 51m

2 stops

$970LATAM Airlines

Wed, Aug 26 - Wed, Sep 2

6:30 pm - 11:35 am

MSP

CUZ

17h 05m

2 stops

5:00 am - 9:30 pm

CUZ

MSP

17h 30m

2 stops

$1,022LATAM Airlines

Fri, Aug 28 - Sat, Dec 5

1:05 pm - 2:30 pm

MSP

EZE

47h 25m

3 stops

4:35 pm - 8:40 pm

EZE

MSP

54h 05m

3 stops

$1,041Air Canada

Thu, May 28 - Sat, Jun 6

1:05 pm - 2:30 pm

MSP

EZE

47h 25m

3 stops

4:35 pm - 8:40 pm

EZE

MSP

30h 05m

2 stops

$1,062Air Canada

Mon, May 11 - Wed, May 27

2:59 pm - 9:40 am

MSP

AEP

16h 41m

2 stops

8:05 pm - 12:04 pm

AEP

MSP

17h 59m

2 stops

$1,297Delta

Mon, May 4 - Mon, May 18

LATAM Airlines flights from Minneapolis to South America

Our best LATAM Airlines deals on Minneapolis to South America flight tickets

LATAM Airlines

May 20

MSP10:12 amMinneapolis St Paul

9h 03m

1 stop

BOG7:15 pmBogotá El Dorado

May 28

BOG8:40 amBogotá El Dorado

9h 28m

1 stop

MSP6:08 pmMinneapolis St Paul

$667

LATAM Airlines

Aug 26

MSP8:50 amMinneapolis St Paul

13h 45m

2 stops

MDE10:35 pmMedellín Jose Maria Cordova Intl

Aug 31

MDE11:10 pmMedellín Jose Maria Cordova Intl

22h 11m

2 stops

MSP9:21 pmMinneapolis St Paul

$688

LATAM Airlines

May 26

MSP9:16 amMinneapolis St Paul

12h 14m

2 stops

MDE9:30 pmMedellín Jose Maria Cordova Intl

Jun 1

MDE5:45 amMedellín Jose Maria Cordova Intl

15h 22m

2 stops

MSP9:07 pmMinneapolis St Paul

$695

Copa Airlines flights from Minneapolis to South America

Our best Copa Airlines deals on Minneapolis to South America flight tickets

Copa Airlines

Jul 23

MSP9:52 amMinneapolis St Paul

22h 23m

2 stops

MDE8:15 amMedellín Jose Maria Cordova Intl

Jul 27

MDE3:10 pmMedellín Jose Maria Cordova Intl

19h 18m

2 stops

MSP10:28 amMinneapolis St Paul

$708

Copa Airlines

Apr 9

MSP10:00 amMinneapolis St Paul

14h 06m

2 stops

BOG12:06 amBogotá El Dorado

Apr 12

BOG6:10 amBogotá El Dorado

26h 40m

2 stops

MSP8:50 amMinneapolis St Paul

$998

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Sun 4/12

7:54 am-9:51 am

1 stop25h 57m

Medellín Jose Maria Cordova Intl

Wed 4/22

1:55 pm-9:39 am

1 stop19h 44m

$434

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Sun 4/12

6:36 am-1:22 pm

1 stop30h 46m

Medellín Jose Maria Cordova Intl

Thu 4/16

2:06 pm-11:04 am

2 stops20h 58m

$436

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Thu 4/30

10:34 am-1:00 pm

1 stop26h 26m

Medellín Jose Maria Cordova Intl

Sun 5/3

1:55 pm-8:54 am

1 stop18h 59m

$457

MinneapolisLima

MSP - LIM

MSPLIM

Minneapolis St Paul

Fri 5/8

1:05 pm-12:50 am

2 stops35h 45m

Lima J Chavez Intl

Tue 5/19

1:40 am-8:40 pm

2 stops43h 00m

$624

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

Mon 9/14

1:10 pm-8:55 am

2 stops19h 45m

Guayaquil Jose Joaquin de Olmedo

Wed 9/30

10:05 am-8:38 pm

2 stops34h 33m

$647

Quickest round-trip

MinneapolisCusco

MSP - CUZ

MSPCUZ

Minneapolis St Paul

Wed 8/26

6:05 pm-11:10 am

2 stops17h 05m

Cusco Velazco Astete

Wed 9/2

7:30 am-12:21 am

2 stops16h 51m

$970

MinneapolisCusco

MSP - CUZ

MSPCUZ

Minneapolis St Paul

Fri 8/28

6:30 pm-11:35 am

2 stops17h 05m

Cusco Velazco Astete

Sat 12/5

5:00 am-9:30 pm

2 stops17h 30m

$1,022

MinneapolisBuenos Aires

MSP - EZE

MSPEZE

Minneapolis St Paul

Thu 5/28

1:05 pm-2:30 pm

3 stops47h 25m

Buenos Aires Ministro Pistarini

Sat 6/6

4:35 pm-8:40 pm

3 stops54h 05m

$1,041

MinneapolisBuenos Aires

MSP - EZE

MSPEZE

Minneapolis St Paul

Mon 5/11

1:05 pm-2:30 pm

3 stops47h 25m

Buenos Aires Ministro Pistarini

Wed 5/27

4:35 pm-8:40 pm

2 stops30h 05m

$1,062

MinneapolisBuenos Aires

MSP - AEP

MSPAEP

Minneapolis St Paul

Mon 5/4

2:59 pm-9:40 am

2 stops16h 41m

Buenos Aires Jorge Newbery

Mon 5/18

8:05 pm-12:04 pm

2 stops17h 59m

$1,297

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Minneapolis to South America

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to South America?

In general, February is the cheapest month to fly from Minneapolis to South America. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $774. If you aren’t able to travel during the month of February, then book flights to South America from Minneapolis during November instead. Flights to South America in November, while not as cheap as those in February, still average around $871.

How far in advance should I book a flight to South America?

You are more likely to see cheaper flights to South America from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to South America for around $907 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to South America from Minneapolis for as low as $648 on momondo.

Can stopping save me money on Minneapolis to South America flights?

You could potentially save up to 40% on your flight if you consider stops on a Minneapolis to South America flight.

Cheap Minneapolis to South America flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to South America

Fastest flight time	8h 25m
Direct flights	None

The fastest flight from Minneapolis to South America takes 8h 25m

There are no direct flights from Minneapolis to South America. There are no popular flight routes from Minneapolis to South America.

Search flight deals

When did momondo last update prices for flights from Minneapolis St Paul Airport to South America?
Prices for flights from Minneapolis St Paul Airport to South America are updated daily.
How many operators does momondo search for flights from Minneapolis St Paul Airport to South America?
As of March 2026, there are 8 operators available to choose from for flights from Minneapolis St Paul Airport to South America.
How old do you have to be to fly from Minneapolis St Paul Airport to South America?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Minneapolis St Paul Airport to South America.
What documentation or ID do you need to fly to South America?
The required travel and health documents for your South America trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at South America. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Minneapolis to South America

Compare and see reviews for airlines that fly from Minneapolis to South America with momondo

Airline	Rating	Free Cancellation	Price
Sun Country Air	PriceFrom $166	Free Cancellation	Rating 6.8 339 reviews	Search Sun Country Air flights
Delta	PriceFrom $239	Free Cancellation	Rating 7.9 8,359 reviews	Search Delta flights
Sky Airlines Peru	PriceFrom $292	Free Cancellation	Rating 0.0 0 reviews	Search Sky Airlines Peru flights
United Airlines	PriceFrom $392	Free Cancellation	Rating 7.4 9,509 reviews	Search United Airlines flights
Copa Airlines	PriceFrom $470	Free Cancellation	Rating 7.5 1,577 reviews	Search Copa Airlines flights
American Airlines	PriceFrom $518	Free Cancellation	Rating 7.1 11,520 reviews	Search American Airlines flights
Avianca	PriceFrom $536	Free Cancellation	Rating 6.5 2,506 reviews	Search Avianca flights
LATAM Airlines	PriceFrom $603	Free Cancellation	Rating 7.4 1,901 reviews	Search LATAM Airlines flights
Air Canada	PriceFrom $698	Free Cancellation	Rating 7.1 10,856 reviews	Search Air Canada flights

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to South America?

Finding the right flight to South America from Minneapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to South America quick and easy, saving you time and money.

Can I find flights from Minneapolis to South America with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Minneapolis to South America flights to just show those with flexible booking policies.

How can momondo help me find flights from Minneapolis to South America?

momondo helps you find the best flight between Minneapolis and South America by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Minneapolis to South America right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to South America from Minneapolis. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.