Which layover airport has the shortest connection time from Minneapolis to Knoxville?

Atlanta (ATL) has the shortest average layover time for this route: 0h 52m.

How many flights depart from Minneapolis to Knoxville on average per day?

The number of flights available between Minneapolis and Knoxville is 4 per day as of September 2025. The most frequent departure time is 8:00PM, with 77% of daily flights leaving in the evening.

Which layover airport has the shortest travel time from Minneapolis to Knoxville?

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 4h 24m.

What is the cheapest airline that flies from Minneapolis St Paul to Knoxville McGhee Tyson?

Frontier and American Airlines are the most popular carriers operating from Minneapolis St Paul to Knoxville McGhee Tyson

How many flights depart from Minneapolis to Knoxville on average per week?

As of September 2025, there are 32 flights per week flying from Minneapolis to Knoxville. The most common day of the week flights depart is Mon, with 19% of flights taking off on this day.

Which airport is the most popular layover for flights between Minneapolis and Knoxville?

Chicago (ORD) was the most common stop: 75% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Minneapolis to Knoxville?

Flights via Chicago (ORD) offer the lowest average round-trip price of $466.

What airlines fly to Knoxville?

Delta, American Airlines and Allegiant Air are the top three most popular airlines that fly to Knoxville from Minneapolis according to our data. Delta is the first choice among our users, with 38% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 6 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport are updated daily.

How many operators does momondo search for flights from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport?

The number of operators available for flights from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport is 5 as of September 2025.

How old do you have to be to fly from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$48 Cheap Flights from Minneapolis to Knoxville in 2025/26

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Find the cheapest flights from Minneapolis to Knoxville

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

8:00 am - 1:11 pmMSP-TYS

28h 11m1 stop

4:47 pm - 11:24 pmTYS-MSP

7h 37m1 stop

$212Multiple Airlines

Find Deal

Wed, Dec 3 - Mon, Dec 8

8:00 am - 1:11 pmMSP-TYS

28h 11m1 stop

6:30 am - 8:52 pmTYS-MSP

15h 22m1 stop

$227Multiple Airlines

Find Deal

Wed, Dec 3 - Thu, Dec 11

6:00 am - 7:32 pmMSP-TYS

12h 32m1 stop

8:17 pm - 11:53 pmTYS-MSP

28h 36m1 stop

$266Frontier

Find Deal

Sun, Oct 19 - Fri, Oct 24

10:15 am - 6:22 pmMSP-TYS

7h 07m1 stop

7:17 pm - 12:14 amTYS-MSP

5h 57m1 stop

$267Frontier

Find Deal

Thu, Oct 30 - Sun, Nov 2

7:00 am - 5:12 pmMSP-TYS

9h 12m1 stop

8:06 am - 5:31 pmTYS-MSP

10h 25m1 stop

$275American Airlines

Find Deal

Thu, Dec 4 - Mon, Dec 8

9:06 am - 9:38 pmMSP-TYS

11h 32m1 stop

8:06 am - 5:28 pmTYS-MSP

10h 22m1 stop

$276American Airlines

Find Deal

Thu, Dec 4 - Tue, Dec 9

7:50 pm - 11:18 pmMSP-TYS

2h 28mnonstop

8:30 am - 10:07 amTYS-MSP

2h 37mnonstop

$299Delta

Find Deal

Wed, Dec 3 - Sat, Dec 6

7:50 pm - 11:18 pmMSP-TYS

2h 28mnonstop

7:39 am - 1:20 pmTYS-MSP

6h 41m1 stop

$309Delta

Find Deal

Thu, Dec 4 - Thu, Dec 11

5:18 pm - 10:39 pmMSP-TYS

4h 21m1 stop

11:07 am - 3:31 pmTYS-MSP

5h 24m1 stop

$330United Airlines

Find Deal

Sat, Jan 3 - Wed, Jan 7

5:18 pm - 10:39 pmMSP-TYS

4h 21m1 stop

2:25 pm - 11:41 pmTYS-MSP

10h 16m2 stops

$335United Airlines

Find Deal

Sat, Jan 3 - Wed, Jan 7

American Airlines flights from Minneapolis to Knoxville

Our best American Airlines deals on Minneapolis to Knoxville flight tickets

American Airlines

Dec 4

MSP7:00 amMinneapolis St Paul

9h 12m

1 stop

TYS5:12 pmKnoxville McGhee Tyson

Dec 8

TYS8:06 amKnoxville McGhee Tyson

10h 25m

1 stop

MSP5:31 pmMinneapolis St Paul

$275

Find similar

American Airlines

Dec 4

MSP9:06 amMinneapolis St Paul

11h 32m

1 stop

TYS9:38 pmKnoxville McGhee Tyson

Dec 9

TYS8:06 amKnoxville McGhee Tyson

10h 22m

1 stop

MSP5:28 pmMinneapolis St Paul

$276

Find similar

American Airlines

Oct 25

MSP7:00 amMinneapolis St Paul

8h 11m

1 stop

TYS4:11 pmKnoxville McGhee Tyson

Oct 28

TYS5:17 pmKnoxville McGhee Tyson

6h 54m

1 stop

MSP11:11 pmMinneapolis St Paul

$297

Find similar

Delta flights from Minneapolis to Knoxville

Our best Delta deals on Minneapolis to Knoxville flight tickets

Delta

Dec 3

MSP7:50 pmMinneapolis St Paul

2h 28m

TYS11:18 pmKnoxville McGhee Tyson

Dec 6

TYS8:30 amKnoxville McGhee Tyson

2h 37m

MSP10:07 amMinneapolis St Paul

$299

Find similar

Delta

Dec 4

MSP7:50 pmMinneapolis St Paul

2h 28m

TYS11:18 pmKnoxville McGhee Tyson

Dec 11

TYS7:39 amKnoxville McGhee Tyson

6h 41m

1 stop

MSP1:20 pmMinneapolis St Paul

$309

Find similar

Delta

Dec 5

MSP8:55 amMinneapolis St Paul

4h 56m

1 stop

TYS2:51 pmKnoxville McGhee Tyson

Dec 9

TYS5:25 amKnoxville McGhee Tyson

7h 50m

1 stop

MSP12:15 pmMinneapolis St Paul

$319

Find similar

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Wed 12/3

8:00 am-1:11 pm

1 stop28h 11m

Knoxville McGhee Tyson

Mon 12/8

4:47 pm-11:24 pm

1 stop7h 37m

$212

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Wed 12/3

8:00 am-1:11 pm

1 stop28h 11m

Knoxville McGhee Tyson

Thu 12/11

6:30 am-8:52 pm

1 stop15h 22m

$227

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Sun 10/19

6:00 am-7:32 pm

1 stop12h 32m

Knoxville McGhee Tyson

Fri 10/24

8:17 pm-11:53 pm

1 stop28h 36m

$266

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Thu 10/30

10:15 am-6:22 pm

1 stop7h 07m

Knoxville McGhee Tyson

Sun 11/2

7:17 pm-12:14 am

1 stop5h 57m

$267

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Thu 12/4

7:00 am-5:12 pm

1 stop9h 12m

Knoxville McGhee Tyson

Mon 12/8

8:06 am-5:31 pm

1 stop10h 25m

$275

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Thu 12/4

9:06 am-9:38 pm

1 stop11h 32m

Knoxville McGhee Tyson

Tue 12/9

8:06 am-5:28 pm

1 stop10h 22m

$276

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Wed 12/3

7:50 pm-11:18 pm

Nonstop2h 28m

Knoxville McGhee Tyson

Sat 12/6

8:30 am-10:07 am

Nonstop2h 37m

$299

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Thu 12/4

7:50 pm-11:18 pm

Nonstop2h 28m

Knoxville McGhee Tyson

Thu 12/11

7:39 am-1:20 pm

1 stop6h 41m

$309

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Sat 1/3

5:18 pm-10:39 pm

1 stop4h 21m

Knoxville McGhee Tyson

Wed 1/7

11:07 am-3:31 pm

1 stop5h 24m

$330

MinneapolisKnoxville

MSP - TYS

MSPTYS

Minneapolis St Paul

Sat 1/3

5:18 pm-10:39 pm

1 stop4h 21m

Knoxville McGhee Tyson

Wed 1/7

2:25 pm-11:41 pm

2 stops10h 16m

$335

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How to get the cheapest flight ticket from Minneapolis to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the cheapest month to fly to Knoxville?

The month of July is, on average, the cheapest month to fly to Knoxville from Minneapolis, with most prices found around $210. If you aren’t able to travel during the month of July, then book flights to Knoxville from Minneapolis during May instead. Flights to Knoxville in May, while not as cheap as those in July, still average around $299.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Minneapolis to Knoxville is on a Friday. Travelers who choose to depart for Knoxville on a Friday will often find tickets for as low as $149. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Minneapolis to Knoxville for around $420.

What is the cheapest time of day to depart on your flight to Knoxville?

In the morning is the cheapest time of day to fly from Minneapolis to Knoxville when you can find flight prices for as low as $133. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $422.

What is the cheapest Minneapolis St Paul to Knoxville McGhee Tyson flight route?

Fly from Minneapolis St Paul to Knoxville McGhee Tyson for the best Minneapolis St Paul - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $379 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Minneapolis for as low as $259 on momondo.

What cabin class options are available on Minneapolis St Paul to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Minneapolis St Paul to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Minneapolis to Knoxville flight prices changed over time?

As of September 2025, prices for Minneapolis to Knoxville flights are approximately 181% more expensive when compared to flights at the same time last year.

When to book flights from Minneapolis to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Minneapolis to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Minneapolis to Knoxville (MSP to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Knoxville

Best Price Found	$248
Fastest flight time	2h 07m
Direct flights	Every day
Airports in Knoxville	1 airport

The best one-way flight to Knoxville from Minneapolis in the past 72 hours is $248. The best round-trip flight deal from Minneapolis to Knoxville found on momondo in the last 72 hours is $349.

The fastest flight from Minneapolis to Knoxville takes 2h 07m

Direct flights go from Minneapolis to Knoxville every day.

There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)

Search flight deals

How far is Minneapolis St Paul to Knoxville McGhee Tyson by plane?
The distance between Minneapolis St Paul and Knoxville McGhee Tyson is about 791.7 mi. By plane, this route typically takes 2h 28m.
When did momondo last update prices for flights from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport are updated daily.
How many operators does momondo search for flights from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport?
The number of operators available for flights from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport is 5 as of September 2025.
How old do you have to be to fly from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The travel and health documents required for your trip to Knoxville McGhee Tyson Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Knoxville McGhee Tyson Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Minneapolis to Knoxville?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Minneapolis to Knoxville is Canadair (Bombardier) Regional Jet 900 (65.61% of total bookings). The next most popular plane models are Airbus A320-100/200 (33.33%), Airbus A321-100/200 (0.53%), and Boeing 737-900 (0.53%).
What is the most popular airline from Minneapolis to Knoxville?
momondo data reveals that the most frequently booked airline on the route from Minneapolis to Knoxville is Delta, representing 49% of all bookings. The subsequent popular airlines are American Airlines at 21%, Allegiant Air at 21%, and United Airlines at 7%.

Best airlines flying from Minneapolis to Knoxville

Compare and see reviews for airlines that fly from Minneapolis to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
Allegiant Air	PriceFrom $84	Free Cancellation	Rating 7.2 699 reviews	Search Allegiant Air flights
Frontier	PriceFrom $121	Free Cancellation	Rating 5.8 3,171 reviews	Search Frontier flights
American Airlines	PriceFrom $296	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Delta	PriceFrom $299	Free Cancellation	Rating 7.9 7,964 reviews	Search Delta flights
United Airlines	PriceFrom $321	Free Cancellation	Rating 7.4 8,926 reviews	Search United Airlines flights

Delta Flights From Minneapolis to Knoxville
Delta flies from Minneapolis to Knoxville around 10 times per week, with 7,964 momondo users rating the airline 7.9/10. The cheapest Delta deal from Minneapolis to Knoxville in the last 72 hours was $299 (round-trip), much lower than the average airfare cost of $417 for Delta flights on this route.

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Crossville

Maryville

Murphy

Alcoa

Oak Ridge

Lenoir City

Newport

Kodak

Dandridge

Clinton

Jefferson City

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Knoxville?

It is quick and easy to find Minneapolis to Knoxville flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Knoxville that suits you.

Can I find flights from Minneapolis to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Minneapolis with this policy.

How can momondo help me find flights from Minneapolis to Knoxville?

Once all potential Minneapolis to Knoxville flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Minneapolis to Knoxville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Minneapolis to Knoxville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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Cheap flights from Minneapolis to Knoxville from $100

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Minneapolis to Knoxville departing on 11/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Minneapolis to Knoxville

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How to get the cheapest flight ticket from Minneapolis to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

What is the cheapest day to depart on your flight to Knoxville?

What is the cheapest time of day to depart on your flight to Knoxville?

What is the cheapest Minneapolis St Paul to Knoxville McGhee Tyson flight route?

Fly from Minneapolis St Paul to Knoxville McGhee Tyson for the best Minneapolis St Paul - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

What cabin class options are available on Minneapolis St Paul to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Minneapolis St Paul to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Minneapolis to Knoxville flight prices changed over time?

As of September 2025, prices for Minneapolis to Knoxville flights are approximately 181% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Minneapolis St Paul to Knoxville McGhee Tyson?

Frontier and American Airlines are the most popular carriers operating from Minneapolis St Paul to Knoxville McGhee Tyson

What airlines fly to Knoxville?

Which airport is the most popular layover for flights between Minneapolis and Knoxville?

Chicago (ORD) was the most common stop: 75% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Minneapolis to Knoxville?

Flights via Chicago (ORD) offer the lowest average round-trip price of $466.

Which layover airport has the shortest travel time from Minneapolis to Knoxville?

Flights connecting via Chicago (ORD) have the shortest average one-way travel time: 4h 24m.

Which layover airport has the shortest connection time from Minneapolis to Knoxville?

Atlanta (ATL) has the shortest average layover time for this route: 0h 52m.

How many flights depart from Minneapolis to Knoxville on average per day?

The number of flights available between Minneapolis and Knoxville is 4 per day as of September 2025. The most frequent departure time is 8:00PM, with 77% of daily flights leaving in the evening.

How many flights depart from Minneapolis to Knoxville on average per week?

As of September 2025, there are 32 flights per week flying from Minneapolis to Knoxville. The most common day of the week flights depart is Mon, with 19% of flights taking off on this day.

When to book flights from Minneapolis to Knoxville

Cheap Minneapolis to Knoxville (MSP to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Minneapolis to Knoxville

Best Price Found

Fastest flight time

Direct flights

Airports in Knoxville

How far is Minneapolis St Paul to Knoxville McGhee Tyson by plane?

When did momondo last update prices for flights from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport?

How many operators does momondo search for flights from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport?

How old do you have to be to fly from Minneapolis St Paul Airport to Knoxville McGhee Tyson Airport?

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

What is the most popular plane model from Minneapolis to Knoxville?

What is the most popular airline from Minneapolis to Knoxville?

Best airlines flying from Minneapolis to Knoxville

Compare and see reviews for airlines that fly from Minneapolis to Knoxville with momondo

Delta Flights From Minneapolis to Knoxville

Traveling to a place near Knoxville?

Why use momondo?

Why should I use momondo to find a flight deal from Minneapolis to Knoxville?

Can I find flights from Minneapolis to Knoxville with flexible booking policies on momondo?

How can momondo help me find flights from Minneapolis to Knoxville?

I’m not ready to book a flight from Minneapolis to Knoxville right now. Can momondo alert me if prices change?

An easier way to manage your Knoxville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing Tennessee