Cheap flights from Minneapolis to Knoxville from $134

The month of August is, on average, the cheapest month to fly to Knoxville from Minneapolis, with most prices found around $359. If you aren’t able to travel during the month of August, then book flights to Knoxville from Minneapolis during February instead. Flights to Knoxville in February, while not as cheap as those in August, still average around $369.

The cheapest day to depart from Minneapolis to Knoxville is on a Saturday. Travelers who choose to depart for Knoxville on a Saturday will often find tickets for as low as $419. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Minneapolis to Knoxville for around $558.

In the morning is the cheapest time of day to fly from Minneapolis to Knoxville when you can find flight prices for as low as $166. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $548.

Fly from Minneapolis St Paul to Knoxville McGhee Tyson for the best Minneapolis St Paul - Knoxville McGhee Tyson flight prices

You are more likely to see cheaper flights to Knoxville from Minneapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $435 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Minneapolis for as low as $285 on momondo.

There are 3 cabin classes available to choose from on Minneapolis to Knoxville flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 34% on your flight if you consider stops on a Minneapolis to Knoxville flight.

As of October 2026, prices for Minneapolis to Knoxville flights are approximately 11% more expensive when compared to flights at the same time last year.

American Airlines and Southwest are the most popular carriers operating from Minneapolis St Paul to Knoxville McGhee Tyson

Delta, American Airlines and Sun Country Air are the top three most popular airlines that fly to Knoxville from Minneapolis according to our data. Delta is the first choice among our users, with 50% of people opting to fly with this airline when traveling to Knoxville. Keep in mind that there are 5 different airlines that fly to Knoxville on a routine basis, so you have a few additional options to choose from.

The number of flights available between Minneapolis and Knoxville is 2 per day as of October 2026. The most frequent departure time is 7:00PM, with 90% of daily flights leaving in the evening.

As of October 2026, there are 19 flights per week flying from Minneapolis to Knoxville. The most common day of the week flights depart is Wed, with 26% of flights taking off on this day.