What is the cheapest airline that flies from Milwaukee-Mitchell to Greenville?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Milwaukee-Mitchell to Greenville

What airlines fly to Greenville?

American Airlines, United Airlines and Frontier are the top three most popular airlines that fly to Greenville from Milwaukee according to our data. American Airlines is the first choice among our users, with 62% of people opting to fly with this airline when traveling to Greenville. Keep in mind that there are 7 different airlines that fly to Greenville on a routine basis, so you have a few additional options to choose from.

Which layover airport offers the lowest fares from Milwaukee to Greenville?

Flights via Charlotte (CLT) offer the lowest average round-trip price of $286.

Which airport is the most popular layover for flights between Milwaukee and Greenville?

Charlotte (CLT) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest travel time from Milwaukee to Greenville?

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 3h 45m.

Which layover airport has the shortest connection time from Milwaukee to Greenville?

Charlotte (CLT) has the shortest average layover time for this route: 0h 53m.

When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Greenville Airport?

Prices for flights from Milwaukee-Mitchell Airport to Greenville Airport are updated daily.

How many operators does momondo search for flights from Milwaukee-Mitchell Airport to Greenville Airport?

As of November 2025, there are 2 operators available to choose from for flights from Milwaukee-Mitchell Airport to Greenville Airport.

How old do you have to be to fly from Milwaukee-Mitchell Airport to Greenville Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Milwaukee-Mitchell Airport to Greenville Airport.

What documentation or ID do you need to fly to Greenville Airport?

The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$144 Cheap Flights from Milwaukee to Greenville in 2025/26

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6:29 pm - 11:41 pmMKE-GSP

4h 12m1 stop

8:19 am - 12:33 pmGSP-MKE

5h 14m1 stop

$297Delta

Find Deal

Sat, Feb 28 - Wed, Mar 4

2:30 pm - 11:59 pmMKE-GSP

8h 29m2 stops

10:51 am - 3:43 pmGSP-MKE

5h 52m1 stop

$302United Airlines

Find Deal

Wed, Dec 17 - Tue, Jan 6

5:45 am - 11:15 amMKE-GSP

4h 30m1 stop

11:42 am - 4:07 pmGSP-MKE

5h 25m1 stop

$309Delta

Find Deal

Thu, Dec 4 - Tue, Dec 9

5:00 am - 2:17 pmMKE-GSP

8h 17m2 stops

12:19 pm - 4:57 pmGSP-MKE

5h 38m1 stop

$314United Airlines

Find Deal

Thu, Dec 4 - Tue, Dec 9

6:00 am - 2:17 pmMKE-GSP

7h 17m2 stops

2:52 pm - 9:47 pmGSP-MKE

7h 55m2 stops

$319United Airlines

Find Deal

Thu, Dec 4 - Tue, Dec 9

4:52 pm - 9:42 pmMKE-GSP

3h 50m1 stop

6:45 am - 10:46 amGSP-MKE

5h 01m1 stop

$321Delta

Find Deal

Thu, Dec 11 - Mon, Dec 15

5:30 am - 2:30 pmMKE-GSP

8h 00m2 stops

4:45 pm - 9:45 pmGSP-MKE

6h 00m1 stop

$326Southwest

Find Deal

Thu, Dec 11 - Mon, Dec 15

3:42 pm - 11:57 pmMKE-GSP

7h 15m2 stops

6:01 am - 12:04 pmGSP-MKE

7h 03m2 stops

$331American Airlines

Find Deal

Thu, Dec 11 - Mon, Dec 15

5:50 am - 4:05 pmMKE-GSP

9h 15m2 stops

10:05 am - 7:55 pmGSP-MKE

10h 50m2 stops

$342Southwest

Find Deal

Wed, Dec 17 - Tue, Jan 6

5:45 am - 11:15 amMKE-GSP

4h 30m1 stop

7:25 am - 12:32 pmGSP-MKE

6h 07m1 stop

$354Delta

Find Deal

Thu, Dec 4 - Sun, Dec 7

American Airlines flights from Milwaukee to Greenville

Our best American Airlines deals on Milwaukee to Greenville flight tickets

American Airlines

Dec 11

MKE3:42 pmMilwaukee-Mitchell

7h 15m

2 stops

GSP11:57 pmGreenville

Dec 15

GSP6:01 amGreenville

7h 03m

2 stops

MKE12:04 pmMilwaukee-Mitchell

$331

Find similar

American Airlines

Feb 28

MKE4:46 pmMilwaukee-Mitchell

6h 08m

2 stops

GSP11:54 pmGreenville

Mar 4

GSP1:49 pmGreenville

4h 08m

1 stop

MKE4:57 pmMilwaukee-Mitchell

$372

Find similar

American Airlines

Nov 25

MKE6:14 amMilwaukee-Mitchell

6h 52m

1 stop

GSP2:06 pmGreenville

Dec 2

GSP12:06 pmGreenville

7h 23m

2 stops

MKE6:29 pmMilwaukee-Mitchell

$377

Find similar

United Airlines flights from Milwaukee to Greenville

Our best United Airlines deals on Milwaukee to Greenville flight tickets

United Airlines

Dec 17

MKE2:30 pmMilwaukee-Mitchell

8h 29m

2 stops

GSP11:59 pmGreenville

Jan 6

GSP10:51 amGreenville

5h 52m

1 stop

MKE3:43 pmMilwaukee-Mitchell

$302

Find similar

United Airlines

Dec 4

MKE5:00 amMilwaukee-Mitchell

8h 17m

2 stops

GSP2:17 pmGreenville

Dec 9

GSP12:19 pmGreenville

5h 38m

1 stop

MKE4:57 pmMilwaukee-Mitchell

$314

Find similar

United Airlines

Dec 4

MKE6:00 amMilwaukee-Mitchell

7h 17m

2 stops

GSP2:17 pmGreenville

Dec 9

GSP2:52 pmGreenville

7h 55m

2 stops

MKE9:47 pmMilwaukee-Mitchell

$319

Find similar

Fly from

Fly to

Route

Depart

Return

Price

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Sat 2/28

6:29 pm-11:41 pm

1 stop4h 12m

Greenville

Wed 3/4

8:19 am-12:33 pm

1 stop5h 14m

$297

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Wed 12/17

2:30 pm-11:59 pm

2 stops8h 29m

Greenville

Tue 1/6

10:51 am-3:43 pm

1 stop5h 52m

$302

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Thu 12/4

5:45 am-11:15 am

1 stop4h 30m

Greenville

Tue 12/9

11:42 am-4:07 pm

1 stop5h 25m

$309

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Thu 12/4

5:00 am-2:17 pm

2 stops8h 17m

Greenville

Tue 12/9

12:19 pm-4:57 pm

1 stop5h 38m

$314

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Thu 12/4

6:00 am-2:17 pm

2 stops7h 17m

Greenville

Tue 12/9

2:52 pm-9:47 pm

2 stops7h 55m

$319

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Thu 12/11

4:52 pm-9:42 pm

1 stop3h 50m

Greenville

Mon 12/15

6:45 am-10:46 am

1 stop5h 01m

$321

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Thu 12/11

5:30 am-2:30 pm

2 stops8h 00m

Greenville

Mon 12/15

4:45 pm-9:45 pm

1 stop6h 00m

$326

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Thu 12/11

3:42 pm-11:57 pm

2 stops7h 15m

Greenville

Mon 12/15

6:01 am-12:04 pm

2 stops7h 03m

$331

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Wed 12/17

5:50 am-4:05 pm

2 stops9h 15m

Greenville

Tue 1/6

10:05 am-7:55 pm

2 stops10h 50m

$342

MilwaukeeGreenville

MKE - GSP

MKEGSP

Milwaukee-Mitchell

Thu 12/4

5:45 am-11:15 am

1 stop4h 30m

Greenville

Sun 12/7

7:25 am-12:32 pm

1 stop6h 07m

$354

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Milwaukee to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from Milwaukee averaging around $316.

What is the cheapest day to depart on your flight to Greenville?

According to our data, Wednesday is the cheapest day to fly to Greenville from Milwaukee. The lowest ticket price found for a Wednesday departure recently was $341. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $516. These prices are subject to change though, so be sure to set up a Price Alert for flights to Greenville.

What is the cheapest time of day to depart on your flight to Greenville?

Our most recent data shows that the best time of day to fly to Greenville is in the afternoon. Flights from Milwaukee to Greenville during this time can be as low as $398. Flights to Greenville are more costly at noon, with an average ticket price of $402. Departure times at noon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Milwaukee to Greenville

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Greenville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Milwaukee to Greenville (MKE to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Greenville

Direct flights	None

There are no direct flights from Milwaukee to Greenville. There are no popular flight routes from Milwaukee to Greenville.

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How far is Milwaukee-Mitchell to Greenville by plane?
The straight-line distance from Milwaukee-Mitchell to Greenville is 637.7 mi. In terms of flight time, this usually takes a little over 3h 50m.
When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Greenville Airport?
Prices for flights from Milwaukee-Mitchell Airport to Greenville Airport are updated daily.
How many operators does momondo search for flights from Milwaukee-Mitchell Airport to Greenville Airport?
As of November 2025, there are 2 operators available to choose from for flights from Milwaukee-Mitchell Airport to Greenville Airport.
How old do you have to be to fly from Milwaukee-Mitchell Airport to Greenville Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Milwaukee-Mitchell Airport to Greenville Airport.
What documentation or ID do you need to fly to Greenville Airport?
The travel and health documents required for your trip to Greenville Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Greenville Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular airline from Milwaukee to Greenville?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Milwaukee to Greenville is Delta (55% of total bookings). The next most popular airline is American Airlines (45%).

Best airlines flying from Milwaukee to Greenville

Compare and see reviews for airlines that fly from Milwaukee to Greenville with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $247	Free Cancellation	Rating 7.9 8,007 reviews		Search Delta flights
American Airlines	PriceFrom $261	Free Cancellation	Rating 7.2 11,051 reviews		Search American Airlines flights

Anderson

Simpsonville

Greenwood

Seneca

Greer

Duncan

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Greenville?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Milwaukee to Greenville. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Milwaukee to Greenville with flexible booking policies on momondo?

Yes. All flights to Greenville from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to Greenville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Milwaukee to Greenville.

I’m not ready to book a flight from Milwaukee to Greenville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Greenville, momondo offers a useful price alert feature which will track prices for flights to Greenville from Milwaukee and alert you when they change.

An easier way to manage your Greenville trip

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Cheap flights from Milwaukee to Greenville from $144

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Milwaukee to Greenville departing on 12/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Milwaukee to Greenville

Our best American Airlines deals on Milwaukee to Greenville flight tickets

United Airlines flights from Milwaukee to Greenville

Our best United Airlines deals on Milwaukee to Greenville flight tickets

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How to get the cheapest flight ticket from Milwaukee to Greenville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Greenville?

The month of August is another great option to travel to Greenville, with average flight prices from Milwaukee averaging around $316.

What is the cheapest day to depart on your flight to Greenville?

What is the cheapest time of day to depart on your flight to Greenville?

What is the cheapest airline that flies from Milwaukee-Mitchell to Greenville?

Delta, United Airlines, and American Airlines are the most popular carriers operating from Milwaukee-Mitchell to Greenville

What airlines fly to Greenville?

Which airport is the most popular layover for flights between Milwaukee and Greenville?

Charlotte (CLT) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Milwaukee to Greenville?

Flights via Charlotte (CLT) offer the lowest average round-trip price of $286.

Which layover airport has the shortest travel time from Milwaukee to Greenville?

Flights connecting via Charlotte (CLT) have the shortest average one-way travel time: 3h 45m.

Which layover airport has the shortest connection time from Milwaukee to Greenville?

Charlotte (CLT) has the shortest average layover time for this route: 0h 53m.

When to book flights from Milwaukee to Greenville

Cheap Milwaukee to Greenville (MKE to GSP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Greenville

Direct flights

How far is Milwaukee-Mitchell to Greenville by plane?

When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Greenville Airport?

How many operators does momondo search for flights from Milwaukee-Mitchell Airport to Greenville Airport?

How old do you have to be to fly from Milwaukee-Mitchell Airport to Greenville Airport?

What documentation or ID do you need to fly to Greenville Airport?

What is the most popular airline from Milwaukee to Greenville?

Best airlines flying from Milwaukee to Greenville

Compare and see reviews for airlines that fly from Milwaukee to Greenville with momondo

Traveling to a place near Greenville?

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Greenville?

Can I find flights from Milwaukee to Greenville with flexible booking policies on momondo?

How can momondo help me find flights from Milwaukee to Greenville?

I’m not ready to book a flight from Milwaukee to Greenville right now. Can momondo alert me if prices change?

An easier way to manage your Greenville trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

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