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Cheap flights from Milwaukee to Des Moines from $122

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Milwaukee to Des Moines departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Milwaukee to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:02 am - 8:23 am
MKE
-
DSM
3h 21m
1 stop
American Airlines Logo
8:53 am - 12:45 pm
DSM
-
MKE
3h 52m
1 stop
$243American Airlines
Wed, Jul 22 - Tue, Jul 28
Southwest Logo
6:00 am - 11:30 am
MKE
-
DSM
5h 30m
1 stop
Southwest Logo
5:20 am - 5:15 pm
DSM
-
MKE
11h 55m
2 stops
$286Southwest
Tue, Jul 21 - Tue, Jul 28
Delta Logo
5:50 pm - 9:24 pm
MKE
-
DSM
3h 34m
1 stop
Delta Logo
6:20 am - 12:27 pm
DSM
-
MKE
6h 07m
1 stop
$289Delta
Thu, Nov 5 - Sun, Nov 8
Southwest Logo
5:15 pm - 11:35 pm
MKE
-
DSM
6h 20m
1 stop
Southwest Logo
4:40 pm - 10:50 pm
DSM
-
MKE
6h 10m
1 stop
$307Southwest
Mon, Jul 20 - Thu, Jul 23
United Airlines Logo
7:50 am - 12:36 pm
MKE
-
DSM
4h 46m
1 stop
United Airlines Logo
11:31 am - 2:58 pm
DSM
-
MKE
3h 27m
1 stop
$308United Airlines
Tue, Nov 17 - Wed, Nov 18
United Airlines Logo
6:18 pm - 11:02 pm
MKE
-
DSM
4h 44m
1 stop
United Airlines Logo
6:21 am - 10:01 am
DSM
-
MKE
3h 40m
1 stop
$313United Airlines
Tue, Nov 17 - Wed, Nov 18
Southwest Logo
5:15 am - 12:50 pm
MKE
-
DSM
7h 35m
1 stop
Southwest Logo
5:10 am - 11:05 am
DSM
-
MKE
5h 55m
1 stop
$327Southwest
Thu, Jul 16 - Thu, Jul 23
Southwest Logo
5:40 am - 11:20 am
MKE
-
DSM
5h 40m
1 stop
Southwest Logo
5:20 am - 12:00 pm
DSM
-
MKE
6h 40m
1 stop
$342Southwest
Wed, Nov 25 - Sun, Nov 29
United Airlines Logo
5:29 pm - 9:22 pm
MKE
-
DSM
3h 53m
1 stop
United Airlines Logo
6:50 pm - 10:29 pm
DSM
-
MKE
3h 39m
1 stop
$347United Airlines
Thu, Jul 16 - Sun, Jul 19
Southwest Logo
10:15 am - 10:50 pm
MKE
-
DSM
12h 35m
2 stops
Southwest Logo
5:20 am - 5:15 pm
DSM
-
MKE
11h 55m
2 stops
$349Southwest
Tue, Jul 21 - Tue, Jul 28

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American Airlines flights from Milwaukee to Des Moines

Our best American Airlines deals on Milwaukee to Des Moines flight tickets
American Airlines
Jul 22
MKE5:02 amMilwaukee-Mitchell
3h 21m
1 stop
DSM8:23 amDes Moines
Jul 28
DSM8:53 amDes Moines
3h 52m
1 stop
MKE12:45 pmMilwaukee-Mitchell
$243
American Airlines
Jul 30
MKE5:02 amMilwaukee-Mitchell
3h 21m
1 stop
DSM8:23 amDes Moines
Aug 2
DSM8:53 amDes Moines
3h 51m
1 stop
MKE12:44 pmMilwaukee-Mitchell
$391
American Airlines
Jul 4
MKE1:44 pmMilwaukee-Mitchell
3h 59m
1 stop
DSM5:43 pmDes Moines
Jul 8
DSM8:53 amDes Moines
3h 52m
1 stop
MKE12:45 pmMilwaukee-Mitchell
$447

United Airlines flights from Milwaukee to Des Moines

Our best United Airlines deals on Milwaukee to Des Moines flight tickets
United Airlines
Jul 3
MKE8:50 amMilwaukee-Mitchell
5h 37m
1 stop
DSM2:27 pmDes Moines
Jul 10
DSM3:24 pmDes Moines
4h 02m
1 stop
MKE7:26 pmMilwaukee-Mitchell
$397
United Airlines
Jul 7
MKE8:50 amMilwaukee-Mitchell
5h 37m
1 stop
DSM2:27 pmDes Moines
Jul 11
DSM3:24 pmDes Moines
3h 24m
1 stop
MKE6:48 pmMilwaukee-Mitchell
$517
United Airlines
Jun 29
MKE6:20 amMilwaukee-Mitchell
4h 07m
1 stop
DSM10:27 amDes Moines
Jun 29
DSM3:01 pmDes Moines
7h 44m
1 stop
MKE10:45 pmMilwaukee-Mitchell
$567

momondo Fare Finder

 
Customize your flight search to find flights from Milwaukee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Milwaukee to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 7/22

5:02 am-8:23 am

1 stop3h 21m

Des Moines

Tue 7/28

8:53 am-12:45 pm

1 stop3h 52m

$243

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 7/21

6:00 am-11:30 am

1 stop5h 30m

Des Moines

Tue 7/28

5:20 am-5:15 pm

2 stops11h 55m

$286

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 11/5

5:50 pm-9:24 pm

1 stop3h 34m

Des Moines

Sun 11/8

6:20 am-12:27 pm

1 stop6h 07m

$289

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Mon 7/20

5:15 pm-11:35 pm

1 stop6h 20m

Des Moines

Thu 7/23

4:40 pm-10:50 pm

1 stop6h 10m

$307

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 11/17

7:50 am-12:36 pm

1 stop4h 46m

Des Moines

Wed 11/18

11:31 am-2:58 pm

1 stop3h 27m

$308

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 11/17

6:18 pm-11:02 pm

1 stop4h 44m

Des Moines

Wed 11/18

6:21 am-10:01 am

1 stop3h 40m

$313

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 7/16

5:15 am-12:50 pm

1 stop7h 35m

Des Moines

Thu 7/23

5:10 am-11:05 am

1 stop5h 55m

$327

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 11/25

5:40 am-11:20 am

1 stop5h 40m

Des Moines

Sun 11/29

5:20 am-12:00 pm

1 stop6h 40m

$342

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 7/16

5:29 pm-9:22 pm

1 stop3h 53m

Des Moines

Sun 7/19

6:50 pm-10:29 pm

1 stop3h 39m

$347

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Tue 7/21

10:15 am-10:50 pm

2 stops12h 35m

Des Moines

Tue 7/28

5:20 am-5:15 pm

2 stops11h 55m

$349

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Milwaukee to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in November, then July is your next best option. Flight prices from Milwaukee to Des Moines during July average around $0.

When to book flights from Milwaukee to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Milwaukee to Des Moines (MKE to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Des Moines

Fastest flight time

3h 27m

Direct flights

None
The fastest flight from Milwaukee to Des Moines takes 3h 27m
There are no direct flights from Milwaukee to Des Moines. There are no popular flight routes from Milwaukee to Des Moines.
Search flight deals

Frequently asked questions about flying from Milwaukee to Des Moines

  • How far is Milwaukee-Mitchell to Des Moines by plane?

    A flight from Milwaukee-Mitchell to Des Moines will travel around 308.8 mi. Flights usually cover this in 3h 27m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Des Moines Airport?

    Prices for flights from Milwaukee-Mitchell Airport to Des Moines Airport were last updated today.

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Milwaukee-Mitchell Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Osceola
Urbandale
Newton
Johnston
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Milwaukee.

Can I find flights from Milwaukee to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Milwaukee. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Milwaukee to Des Moines right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Milwaukee to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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