Latest deals
Insights
When to book
FAQs
Price Alerts

Cheap flights from Milwaukee to Des Moines from $125

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Milwaukee to Des Moines departing on 8/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Milwaukee to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
11:18 am - 5:28 pmMKE  Milwaukee-Mitchell-DSM Des Moines
6h 10m1 stop Chicago O'Hare Intl
United Airlines Logo
6:24 am - 10:00 amDSM  Des Moines-MKE Milwaukee-Mitchell
3h 36m1 stop Chicago O'Hare Intl
$249United Airlines
Sat, Sep 5 - Fri, Sep 11
American Airlines Logo
8:20 am - 1:25 pmMKE  Milwaukee-Mitchell-DSM Des Moines
5h 05m1 stop Chicago O'Hare Intl
American Airlines Logo
1:55 pm - 7:59 pmDSM  Des Moines-MKE Milwaukee-Mitchell
6h 04m1 stop Chicago O'Hare Intl
$249American Airlines
Sat, Sep 5 - Sun, Sep 6
United Airlines Logo
7:18 am - 12:20 pmMKE  Milwaukee-Mitchell-DSM Des Moines
5h 02m1 stop Chicago O'Hare Intl
United Airlines Logo
8:00 am - 2:33 pmDSM  Des Moines-MKE Milwaukee-Mitchell
6h 33m1 stop Chicago O'Hare Intl
$265United Airlines
Thu, Aug 27 - Sat, Aug 29
American Airlines Logo
5:00 am - 10:00 amMKE  Milwaukee-Mitchell-DSM Des Moines
5h 00m1 stop Chicago O'Hare Intl
American Airlines Logo
6:55 am - 10:57 amDSM  Des Moines-MKE Milwaukee-Mitchell
4h 02m1 stop Chicago O'Hare Intl
$265American Airlines
Tue, Sep 1 - Mon, Sep 7
American Airlines Logo
1:17 pm - 7:19 pmMKE  Milwaukee-Mitchell-DSM Des Moines
6h 02m1 stop Chicago O'Hare Intl
American Airlines Logo
5:56 pm - 9:54 pmDSM  Des Moines-MKE Milwaukee-Mitchell
3h 58m1 stop Chicago O'Hare Intl
$265American Airlines
Wed, Sep 2 - Wed, Sep 9
United Airlines Logo
5:00 am - 10:26 amMKE  Milwaukee-Mitchell-DSM Des Moines
5h 26m1 stop Chicago O'Hare Intl
United Airlines Logo
8:00 am - 2:33 pmDSM  Des Moines-MKE Milwaukee-Mitchell
6h 33m1 stop Chicago O'Hare Intl
$274United Airlines
Fri, Aug 28 - Sat, Aug 29
American Airlines Logo
1:17 pm - 7:19 pmMKE  Milwaukee-Mitchell-DSM Des Moines
6h 02m1 stop Chicago O'Hare Intl
American Airlines Logo
7:00 am - 11:02 amDSM  Des Moines-MKE Milwaukee-Mitchell
4h 02m1 stop Chicago O'Hare Intl
$274American Airlines
Fri, Aug 28 - Sat, Aug 29
Southwest Logo
6:20 am - 1:55 pmMKE  Milwaukee-Mitchell-DSM Des Moines
7h 35m1 stop Denver Intl
Southwest Logo
6:10 am - 8:00 pmDSM  Des Moines-MKE Milwaukee-Mitchell
13h 50m2 stops Chicago Midway Lambert-St Louis
$276Southwest
Wed, Sep 2 - Wed, Sep 9
Southwest Logo
5:45 am - 11:25 amMKE  Milwaukee-Mitchell-DSM Des Moines
5h 40m1 stop Chicago Midway
Southwest Logo
2:25 pm - 9:25 pmDSM  Des Moines-MKE Milwaukee-Mitchell
7h 00m1 stop Denver Intl
$281Southwest
Thu, Sep 3 - Thu, Sep 10
United Airlines Logo
10:19 am - 2:16 pmMKE  Milwaukee-Mitchell-DSM Des Moines
3h 57m1 stop Chicago O'Hare Intl
United Airlines Logo
8:00 am - 11:30 amDSM  Des Moines-MKE Milwaukee-Mitchell
3h 30m1 stop Chicago O'Hare Intl
$281United Airlines
Thu, Sep 3 - Thu, Sep 10

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

United Airlines flights from Milwaukee to Des Moines

Our best United Airlines deals on Milwaukee to Des Moines flight tickets
United Airlines
Sep 5
MKE11:18 amMilwaukee-Mitchell
6h 10m
1 stop
DSM5:28 pmDes Moines
Sep 11
DSM6:24 amDes Moines
3h 36m
1 stop
MKE10:00 amMilwaukee-Mitchell
$249
United Airlines
Aug 28
MKE5:00 amMilwaukee-Mitchell
5h 26m
1 stop
DSM10:26 amDes Moines
Aug 29
DSM8:00 amDes Moines
6h 33m
1 stop
MKE2:33 pmMilwaukee-Mitchell
$274
United Airlines
Oct 3
MKE8:30 amMilwaukee-Mitchell
4h 02m
1 stop
DSM12:32 pmDes Moines
Oct 4
DSM6:55 pmDes Moines
4h 04m
1 stop
MKE10:59 pmMilwaukee-Mitchell
$299

Southwest flights from Milwaukee to Des Moines

Our best Southwest deals on Milwaukee to Des Moines flight tickets
Southwest
Sep 2
MKE6:20 amMilwaukee-Mitchell
7h 35m
1 stop
DSM1:55 pmDes Moines
Sep 9
DSM6:10 amDes Moines
13h 50m
2 stops
MKE8:00 pmMilwaukee-Mitchell
$276
Southwest
Sep 3
MKE5:45 amMilwaukee-Mitchell
5h 40m
1 stop
DSM11:25 amDes Moines
Sep 10
DSM2:25 pmDes Moines
7h 00m
1 stop
MKE9:25 pmMilwaukee-Mitchell
$281
Southwest
Sep 5
MKE6:15 amMilwaukee-Mitchell
13h 15m
2 stops
DSM7:30 pmDes Moines
Sep 11
DSM3:50 pmDes Moines
5h 35m
1 stop
MKE9:25 pmMilwaukee-Mitchell
$285

momondo Fare Finder

 
Customize your flight search to find flights from Milwaukee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 8, 2026.
Use the filters below to find and compare flights from Milwaukee to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MilwaukeeDes Moines

MKE Milwaukee-Mitchell - DSM Des Moines

MKEDSM

Milwaukee-Mitchell

Sat 9/5

11:18 am-5:28 pm

1 stop6h 10m

Des Moines

Fri 9/11

6:24 am-10:00 am

1 stop3h 36m

$249

MilwaukeeDes Moines

MKE Milwaukee-Mitchell - DSM Des Moines

MKEDSM

Milwaukee-Mitchell

Sat 9/5

8:20 am-1:25 pm

1 stop5h 05m

Des Moines

Sun 9/6

1:55 pm-7:59 pm

1 stop6h 04m

$249

MilwaukeeDes Moines

MKE Milwaukee-Mitchell - DSM Des Moines

MKEDSM

Milwaukee-Mitchell

Thu 8/27

7:18 am-12:20 pm

1 stop5h 02m

Des Moines

Sat 8/29

8:00 am-2:33 pm

1 stop6h 33m

$265

MilwaukeeDes Moines

MKE Milwaukee-Mitchell - DSM Des Moines

MKEDSM

Milwaukee-Mitchell

Tue 9/1

5:00 am-10:00 am

1 stop5h 00m

Des Moines

Mon 9/7

6:55 am-10:57 am

1 stop4h 02m

$265

MilwaukeeDes Moines

MKE Milwaukee-Mitchell - DSM Des Moines

MKEDSM

Milwaukee-Mitchell

Wed 9/2

1:17 pm-7:19 pm

1 stop6h 02m

Des Moines

Wed 9/9

5:56 pm-9:54 pm

1 stop3h 58m

$265

MilwaukeeDes Moines

MKE Milwaukee-Mitchell - DSM Des Moines

MKEDSM

Milwaukee-Mitchell

Fri 8/28

5:00 am-10:26 am

1 stop5h 26m

Des Moines

Sat 8/29

8:00 am-2:33 pm

1 stop6h 33m

$274

MilwaukeeDes Moines

MKE Milwaukee-Mitchell - DSM Des Moines

MKEDSM

Milwaukee-Mitchell

Fri 8/28

1:17 pm-7:19 pm

1 stop6h 02m

Des Moines

Sat 8/29

7:00 am-11:02 am

1 stop4h 02m

$274

MilwaukeeDes Moines

MKE Milwaukee-Mitchell - DSM Des Moines

MKEDSM

Milwaukee-Mitchell

Wed 9/2

6:20 am-1:55 pm

1 stop7h 35m

Des Moines

Wed 9/9

6:10 am-8:00 pm

2 stops13h 50m

$276

MilwaukeeDes Moines

MKE Milwaukee-Mitchell - DSM Des Moines

MKEDSM

Milwaukee-Mitchell

Thu 9/3

5:45 am-11:25 am

1 stop5h 40m

Des Moines

Thu 9/10

2:25 pm-9:25 pm

1 stop7h 00m

$281
Quickest round-trip

MilwaukeeDes Moines

MKE Milwaukee-Mitchell - DSM Des Moines

MKEDSM

Milwaukee-Mitchell

Thu 9/3

10:19 am-2:16 pm

1 stop3h 57m

Des Moines

Thu 9/10

8:00 am-11:30 am

1 stop3h 30m

$281

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Milwaukee to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in September, then August is your next best option. Flight prices from Milwaukee to Des Moines during August average around $196.

When to book flights from Milwaukee to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Milwaukee to Des Moines (MKE to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Des Moines

Fastest flight time

3h 48m

Direct flights

None
The fastest flight from Milwaukee to Des Moines takes 3h 48m
There are no direct flights from Milwaukee to Des Moines. There are no popular flight routes from Milwaukee to Des Moines.
Search flight deals

Frequently asked questions about flying from Milwaukee to Des Moines

  • How far is Milwaukee-Mitchell to Des Moines by plane?

    A flight from Milwaukee-Mitchell to Des Moines will travel around 308.8 mi. Flights usually cover this in 3h 48m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Des Moines Airport?

    Prices for flights from Milwaukee-Mitchell Airport to Des Moines Airport were last updated today.

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Milwaukee-Mitchell Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Clive
Altoona
Pella
Urbandale
Newton
Osceola
Johnston
Boone
Oskaloosa
Norwalk
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Milwaukee.

Can I find flights from Milwaukee to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Milwaukee. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Milwaukee to Des Moines right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Milwaukee to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Mon 9/7
Mon 9/14
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States