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Cheap flights from Milwaukee to Des Moines from $128

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Milwaukee to Des Moines departing on 4/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Milwaukee to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
5:50 am - 11:25 am
MKE
-
DSM
5h 35m
1 stop
Southwest Logo
4:20 pm - 10:15 pm
DSM
-
MKE
5h 55m
1 stop
$242Southwest
Wed, May 6 - Fri, May 8
Southwest Logo
8:00 am - 10:10 pm
MKE
-
DSM
14h 10m
2 stops
Southwest Logo
4:20 pm - 10:15 pm
DSM
-
MKE
5h 55m
1 stop
$253Southwest
Wed, May 6 - Fri, May 8
Delta Logo
5:48 pm - 9:03 pm
MKE
-
DSM
3h 15m
1 stop
Delta Logo
7:01 am - 11:28 am
DSM
-
MKE
4h 27m
1 stop
$261Delta
Mon, May 18 - Tue, May 19
Delta Logo
6:30 am - 10:16 am
MKE
-
DSM
3h 46m
1 stop
Delta Logo
7:00 am - 10:13 am
DSM
-
MKE
3h 13m
1 stop
$267Delta
Sat, Apr 18 - Sat, Apr 25
United Airlines Logo
7:41 pm - 11:17 pm
MKE
-
DSM
3h 36m
1 stop
United Airlines Logo
7:16 pm - 10:30 pm
DSM
-
MKE
3h 14m
1 stop
$275United Airlines
Thu, Apr 23 - Sun, Apr 26
Southwest Logo
5:40 am - 8:55 pm
MKE
-
DSM
15h 15m
2 stops
Southwest Logo
5:35 am - 11:15 am
DSM
-
MKE
5h 40m
1 stop
$278Southwest
Sat, Apr 18 - Sat, Apr 25
Southwest Logo
5:50 am - 11:25 am
MKE
-
DSM
5h 35m
1 stop
Southwest Logo
4:20 pm - 10:15 pm
DSM
-
MKE
5h 55m
1 stop
$287Southwest
Sun, May 10 - Thu, May 14
United Airlines Logo
7:41 pm - 11:17 pm
MKE
-
DSM
3h 36m
1 stop
United Airlines Logo
3:21 pm - 9:49 pm
DSM
-
MKE
6h 28m
1 stop
$292United Airlines
Thu, Apr 23 - Sun, Apr 26
United Airlines Logo
1:46 pm - 7:26 pm
MKE
-
DSM
5h 40m
1 stop
United Airlines Logo
7:05 pm - 11:59 pm
DSM
-
MKE
4h 54m
1 stop
$293United Airlines
Sat, May 2 - Wed, May 6
Southwest Logo
5:40 am - 8:55 pm
MKE
-
DSM
15h 15m
2 stops
Southwest Logo
5:35 am - 8:10 pm
DSM
-
MKE
14h 35m
2 stops
$294Southwest
Sat, Apr 18 - Sat, Apr 25

Delta flights from Milwaukee to Des Moines

Our best Delta deals on Milwaukee to Des Moines flight tickets
Delta
May 18
MKE5:48 pmMilwaukee-Mitchell
3h 15m
1 stop
DSM9:03 pmDes Moines
May 19
DSM7:01 amDes Moines
4h 27m
1 stop
MKE11:28 amMilwaukee-Mitchell
$261
Delta
Apr 18
MKE6:30 amMilwaukee-Mitchell
3h 46m
1 stop
DSM10:16 amDes Moines
Apr 25
DSM7:00 amDes Moines
3h 13m
1 stop
MKE10:13 amMilwaukee-Mitchell
$267
Delta
Aug 21
MKE12:00 pmMilwaukee-Mitchell
5h 09m
1 stop
DSM5:09 pmDes Moines
Aug 23
DSM7:00 amDes Moines
4h 11m
1 stop
MKE11:11 amMilwaukee-Mitchell
$307

United Airlines flights from Milwaukee to Des Moines

Our best United Airlines deals on Milwaukee to Des Moines flight tickets
United Airlines
Apr 23
MKE7:41 pmMilwaukee-Mitchell
3h 36m
1 stop
DSM11:17 pmDes Moines
Apr 26
DSM7:16 pmDes Moines
3h 14m
1 stop
MKE10:30 pmMilwaukee-Mitchell
$275
United Airlines
Apr 23
MKE7:41 pmMilwaukee-Mitchell
3h 36m
1 stop
DSM11:17 pmDes Moines
Apr 26
DSM3:21 pmDes Moines
6h 28m
1 stop
MKE9:49 pmMilwaukee-Mitchell
$292
United Airlines
May 2
MKE1:46 pmMilwaukee-Mitchell
5h 40m
1 stop
DSM7:26 pmDes Moines
May 6
DSM7:05 pmDes Moines
4h 54m
1 stop
MKE11:59 pmMilwaukee-Mitchell
$293

momondo Fare Finder

 
Customize your flight search to find flights from Milwaukee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 24, 2026.
Use the filters below to find and compare flights from Milwaukee to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 5/6

5:50 am-11:25 am

1 stop5h 35m

Des Moines

Fri 5/8

4:20 pm-10:15 pm

1 stop5h 55m

$242

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 5/6

8:00 am-10:10 pm

2 stops14h 10m

Des Moines

Fri 5/8

4:20 pm-10:15 pm

1 stop5h 55m

$253

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Mon 5/18

5:48 pm-9:03 pm

1 stop3h 15m

Des Moines

Tue 5/19

7:01 am-11:28 am

1 stop4h 27m

$261

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 4/18

6:30 am-10:16 am

1 stop3h 46m

Des Moines

Sat 4/25

7:00 am-10:13 am

1 stop3h 13m

$267
Quickest round-trip

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 4/23

7:41 pm-11:17 pm

1 stop3h 36m

Des Moines

Sun 4/26

7:16 pm-10:30 pm

1 stop3h 14m

$275

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 4/18

5:40 am-8:55 pm

2 stops15h 15m

Des Moines

Sat 4/25

5:35 am-11:15 am

1 stop5h 40m

$278

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sun 5/10

5:50 am-11:25 am

1 stop5h 35m

Des Moines

Thu 5/14

4:20 pm-10:15 pm

1 stop5h 55m

$287

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 4/23

7:41 pm-11:17 pm

1 stop3h 36m

Des Moines

Sun 4/26

3:21 pm-9:49 pm

1 stop6h 28m

$292

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 5/2

1:46 pm-7:26 pm

1 stop5h 40m

Des Moines

Wed 5/6

7:05 pm-11:59 pm

1 stop4h 54m

$293

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 4/18

5:40 am-8:55 pm

2 stops15h 15m

Des Moines

Sat 4/25

5:35 am-8:10 pm

2 stops14h 35m

$294

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Milwaukee to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Milwaukee-Mitchell to Des Moines?

United Airlines and Delta are the most popular carriers operating from Milwaukee-Mitchell to Des Moines

What airlines fly to Des Moines?

United Airlines, American Airlines and Delta are the top three most popular airlines that fly to Des Moines from Milwaukee according to our data. United Airlines is the first choice among our users, with 53% of people opting to fly with this airline when traveling to Des Moines. Keep in mind that there are 3 different airlines that fly to Des Moines on a routine basis, so you have a few additional options to choose from.

When to book flights from Milwaukee to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Milwaukee to Des Moines (MKE to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Des Moines

Fastest flight time

3h 36m

Direct flights

None
The fastest flight from Milwaukee to Des Moines takes 3h 36m
There are no direct flights from Milwaukee to Des Moines. There are no popular flight routes from Milwaukee to Des Moines.
Search flight deals

  • How far is Milwaukee-Mitchell to Des Moines by plane?

    A flight from Milwaukee-Mitchell to Des Moines will travel around 308.8 mi. Flights usually cover this in 3h 36m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Des Moines Airport?

    Prices for flights from Milwaukee-Mitchell Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Milwaukee-Mitchell Airport to Des Moines Airport?

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Milwaukee-Mitchell Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Milwaukee to Des Moines?

Best airlines flying from Milwaukee to Des Moines

Compare and see reviews for airlines that fly from Milwaukee to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $174Free CancellationRating
7.1
11,491 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Urbandale
Pella
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Milwaukee.

Can I find flights from Milwaukee to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Milwaukee. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Milwaukee to Des Moines right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Milwaukee to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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