Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Milwaukee to Des Moines from $120

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Milwaukee to Des Moines departing on 5/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Milwaukee to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
6:50 am - 12:29 pm
MKE
-
DSM
5h 39m
1 stop
United Airlines Logo
3:21 pm - 8:48 pm
DSM
-
MKE
5h 27m
1 stop
$271United Airlines
Thu, Apr 16 - Sun, Apr 19
United Airlines Logo
7:00 pm - 12:30 am
MKE
-
DSM
5h 30m
1 stop
United Airlines Logo
3:24 pm - 6:51 pm
DSM
-
MKE
3h 27m
1 stop
$287United Airlines
Fri, Jun 19 - Sun, Jun 21
United Airlines Logo
6:00 am - 10:30 am
MKE
-
DSM
4h 30m
1 stop
United Airlines Logo
1:10 pm - 4:47 pm
DSM
-
MKE
3h 37m
1 stop
$303United Airlines
Fri, Mar 27 - Sun, Mar 29
Southwest Logo
4:50 pm - 11:05 pm
MKE
-
DSM
6h 15m
1 stop
Southwest Logo
4:20 pm - 11:55 pm
DSM
-
MKE
7h 35m
2 stops
$363Southwest
Thu, Apr 16 - Sun, Apr 19
American Airlines Logo
6:00 am - 11:40 pm
MKE
-
DSM
17h 40m
1 stop
American Airlines Logo
7:44 pm - 10:57 pm
DSM
-
MKE
3h 13m
1 stop
$370American Airlines
Sun, Feb 22 - Thu, Feb 26
Southwest Logo
8:00 am - 11:05 pm
MKE
-
DSM
15h 05m
2 stops
Southwest Logo
4:20 pm - 11:55 pm
DSM
-
MKE
7h 35m
2 stops
$374Southwest
Thu, Apr 16 - Sun, Apr 19
Southwest Logo
12:55 pm - 11:35 pm
MKE
-
DSM
10h 40m
2 stops
Southwest Logo
6:15 pm - 10:20 pm
DSM
-
MKE
4h 05m
1 stop
$388Southwest
Sun, Feb 22 - Thu, Feb 26
American Airlines Logo
9:00 am - 11:40 pm
MKE
-
DSM
14h 40m
1 stop
American Airlines Logo
7:44 pm - 11:56 am
DSM
-
MKE
16h 12m
1 stop
$409American Airlines
Sat, Feb 21 - Wed, Feb 25
American Airlines Logo
5:00 am - 9:01 am
MKE
-
DSM
28h 01m
1 stop
American Airlines Logo
6:32 am - 10:57 pm
DSM
-
MKE
16h 25m
1 stop
$413American Airlines
Thu, Feb 19 - Mon, Feb 23
United Airlines Logo
1:25 pm - 5:47 pm
MKE
-
DSM
4h 22m
1 stop
United Airlines Logo
6:55 pm - 10:28 pm
DSM
-
MKE
3h 33m
1 stop
$427United Airlines
Wed, Feb 18 - Sun, Feb 22

United Airlines flights from Milwaukee to Des Moines

Our best United Airlines deals on Milwaukee to Des Moines flight tickets
United Airlines
Apr 16
MKE6:50 amMilwaukee-Mitchell
5h 39m
1 stop
DSM12:29 pmDes Moines
Apr 19
DSM3:21 pmDes Moines
5h 27m
1 stop
MKE8:48 pmMilwaukee-Mitchell
$271
United Airlines
Jun 19
MKE7:00 pmMilwaukee-Mitchell
5h 30m
1 stop
DSM12:30 amDes Moines
Jun 21
DSM3:24 pmDes Moines
3h 27m
1 stop
MKE6:51 pmMilwaukee-Mitchell
$287
United Airlines
Mar 27
MKE6:00 amMilwaukee-Mitchell
4h 30m
1 stop
DSM10:30 amDes Moines
Mar 29
DSM1:10 pmDes Moines
3h 37m
1 stop
MKE4:47 pmMilwaukee-Mitchell
$303

Southwest flights from Milwaukee to Des Moines

Our best Southwest deals on Milwaukee to Des Moines flight tickets
Southwest
Apr 16
MKE4:50 pmMilwaukee-Mitchell
6h 15m
1 stop
DSM11:05 pmDes Moines
Apr 19
DSM4:20 pmDes Moines
7h 35m
2 stops
MKE11:55 pmMilwaukee-Mitchell
$363
Southwest
Apr 16
MKE8:00 amMilwaukee-Mitchell
15h 05m
2 stops
DSM11:05 pmDes Moines
Apr 19
DSM4:20 pmDes Moines
7h 35m
2 stops
MKE11:55 pmMilwaukee-Mitchell
$374
Southwest
Feb 22
MKE12:55 pmMilwaukee-Mitchell
10h 40m
2 stops
DSM11:35 pmDes Moines
Feb 26
DSM6:15 pmDes Moines
4h 05m
1 stop
MKE10:20 pmMilwaukee-Mitchell
$388

momondo Fare Finder

 
Customize your flight search to find flights from Milwaukee to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 6, 2026.
Use the filters below to find and compare flights from Milwaukee to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 4/16

6:50 am-12:29 pm

1 stop5h 39m

Des Moines

Sun 4/19

3:21 pm-8:48 pm

1 stop5h 27m

$271

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Fri 6/19

7:00 pm-12:30 am

1 stop5h 30m

Des Moines

Sun 6/21

3:24 pm-6:51 pm

1 stop3h 27m

$287

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Fri 3/27

6:00 am-10:30 am

1 stop4h 30m

Des Moines

Sun 3/29

1:10 pm-4:47 pm

1 stop3h 37m

$303

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 4/16

4:50 pm-11:05 pm

1 stop6h 15m

Des Moines

Sun 4/19

4:20 pm-11:55 pm

2 stops7h 35m

$363

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sun 2/22

6:00 am-11:40 pm

1 stop17h 40m

Des Moines

Thu 2/26

7:44 pm-10:57 pm

1 stop3h 13m

$370

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 4/16

8:00 am-11:05 pm

2 stops15h 05m

Des Moines

Sun 4/19

4:20 pm-11:55 pm

2 stops7h 35m

$374

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sun 2/22

12:55 pm-11:35 pm

2 stops10h 40m

Des Moines

Thu 2/26

6:15 pm-10:20 pm

1 stop4h 05m

$388

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Sat 2/21

9:00 am-11:40 pm

1 stop14h 40m

Des Moines

Wed 2/25

7:44 pm-11:56 am

1 stop16h 12m

$409

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Thu 2/19

5:00 am-9:01 am

1 stop28h 01m

Des Moines

Mon 2/23

6:32 am-10:57 pm

1 stop16h 25m

$413

MilwaukeeDes Moines

MKE - DSM

MKEDSM

Milwaukee-Mitchell

Wed 2/18

1:25 pm-5:47 pm

1 stop4h 22m

Des Moines

Sun 2/22

6:55 pm-10:28 pm

1 stop3h 33m

$427

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Des Moines from

How to get the cheapest flight ticket from Milwaukee to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Milwaukee-Mitchell to Des Moines?

Delta, Southwest, and American Airlines are the most popular carriers operating from Milwaukee-Mitchell to Des Moines

When to book flights from Milwaukee to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Milwaukee to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Milwaukee to Des Moines (MKE to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Milwaukee to Des Moines

Fastest flight time

3h 53m

Direct flights

None
The fastest flight from Milwaukee to Des Moines takes 3h 53m
There are no direct flights from Milwaukee to Des Moines. There are no popular flight routes from Milwaukee to Des Moines.
Search flight deals

  • How far is Milwaukee-Mitchell to Des Moines by plane?

    A flight from Milwaukee-Mitchell to Des Moines will travel around 308.8 mi. Flights usually cover this in 3h 53m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Milwaukee-Mitchell Airport to Des Moines Airport?

    Prices for flights from Milwaukee-Mitchell Airport to Des Moines Airport were last updated today.

  • How many operators does momondo search for flights from Milwaukee-Mitchell Airport to Des Moines Airport?

  • How old do you have to be to fly from Milwaukee-Mitchell Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Milwaukee-Mitchell Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Milwaukee to Des Moines?

Best airlines flying from Milwaukee to Des Moines

Compare and see reviews for airlines that fly from Milwaukee to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $174Free CancellationRating
7.2
11,237 reviews
Search American Airlines flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Boone
Osceola
Norwalk
Oskaloosa
Grinnell
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Milwaukee to Des Moines?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Des Moines from Milwaukee.

Can I find flights from Milwaukee to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Milwaukee on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Milwaukee to Des Moines?

momondo provides multiple filters to help you find the best flight to Des Moines from Milwaukee. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Milwaukee to Des Moines right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Milwaukee to Des Moines flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Des Moines trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sun 3/8
Sun 3/15
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States