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Cheap flights from Chicago Midway Airport to South Carolina from $59

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to South Carolina departing on 2/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Chicago Midway Airport to South Carolina

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:30 am - 7:58 am
MDW
-
CLT
23h 28m1 stop
Multiple Airlines Logo
7:00 am - 1:56 pm
CLT
-
MDW
7h 56m1 stop
$147Multiple Airlines
Thu, Feb 19 - Thu, Feb 26
Southwest Logo
2:30 pm - 5:20 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
8:25 pm - 9:30 pm
CLT
-
MDW
2h 05mnonstop
$148Southwest
Sat, Feb 14 - Fri, Feb 20
Southwest Logo
2:30 pm - 5:20 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
8:25 pm - 9:30 pm
CLT
-
MDW
2h 05mnonstop
$159Southwest
Sat, Feb 14 - Mon, Feb 16
Frontier Logo
7:30 am - 7:58 am
MDW
-
CLT
23h 28m1 stop
Frontier Logo
10:50 am - 1:08 pm
CLT
-
MDW
27h 18m1 stop
$165Frontier
Thu, Feb 19 - Sun, Feb 22
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
6:20 pm - 7:25 pm
CLT
-
MDW
2h 05mnonstop
$168Southwest
Wed, Jan 21 - Sun, Jan 25
Multiple Airlines Logo
1:00 pm - 9:30 am
MDW
-
CLT
19h 30m1 stop
Multiple Airlines Logo
11:12 am - 7:52 pm
CLT
-
MDW
9h 40m1 stop
$175Multiple Airlines
Thu, Feb 5 - Sun, Feb 8
Southwest Logo
1:30 pm - 4:20 pm
MDW
-
CLT
1h 50mnonstop
Southwest Logo
5:50 pm - 6:55 pm
CLT
-
MDW
2h 05mnonstop
$177Southwest
Fri, Jan 30 - Mon, Feb 2
Delta Logo
10:46 am - 6:10 pm
MDW
-
CLT
6h 24m1 stop
Delta Logo
2:25 pm - 5:29 pm
CLT
-
MDW
4h 04m1 stop
$178Delta
Sat, Jan 24 - Tue, Jan 27
Frontier Logo
8:19 pm - 8:18 am
MDW
-
CLT
10h 59m1 stop
Frontier Logo
8:48 am - 3:19 pm
CLT
-
MDW
7h 31m1 stop
$182Frontier
Thu, Jan 15 - Mon, Jan 19
Delta Logo
6:14 pm - 11:50 pm
MDW
-
GSP
4h 36m1 stop
Delta Logo
6:50 am - 9:53 am
GSP
-
MDW
4h 03m1 stop
$215Delta
Wed, Jan 21 - Wed, Jan 28

Frontier flights from Chicago Midway Airport to South Carolina

Our best Frontier deals on Chicago Midway Airport to South Carolina flight tickets
Frontier
Feb 19
MDW7:30 amChicago Midway
23h 28m
1 stop
CLT7:58 amCharlotte Douglas
Feb 22
CLT10:50 amCharlotte Douglas
27h 18m
1 stop
MDW1:08 pmChicago Midway
$165
Find similar
Frontier
Jan 15
MDW8:19 pmChicago Midway
10h 59m
1 stop
CLT8:18 amCharlotte Douglas
Jan 19
CLT8:48 amCharlotte Douglas
7h 31m
1 stop
MDW3:19 pmChicago Midway
$182
Find similar
Frontier
Feb 5
MDW1:00 pmChicago Midway
28h 07m
1 stop
CLT6:07 pmCharlotte Douglas
Feb 9
CLT10:15 amCharlotte Douglas
6h 34m
1 stop
MDW3:49 pmChicago Midway
$191
Find similar

Southwest flights from Chicago Midway Airport to South Carolina

Our best Southwest deals on Chicago Midway Airport to South Carolina flight tickets
Southwest
Feb 14
MDW2:30 pmChicago Midway
1h 50m
CLT5:20 pmCharlotte Douglas
Feb 20
CLT8:25 pmCharlotte Douglas
2h 05m
MDW9:30 pmChicago Midway
$148
Find similar
Southwest
Feb 14
MDW2:30 pmChicago Midway
1h 50m
CLT5:20 pmCharlotte Douglas
Feb 16
CLT8:25 pmCharlotte Douglas
2h 05m
MDW9:30 pmChicago Midway
$159
Find similar
Southwest
Jan 21
MDW1:30 pmChicago Midway
1h 50m
CLT4:20 pmCharlotte Douglas
Jan 25
CLT6:20 pmCharlotte Douglas
2h 05m
MDW7:25 pmChicago Midway
$168
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Chicago Midway Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 2/19

7:30 am-7:58 am

1 stop23h 28m

Charlotte Douglas

Thu 2/26

7:00 am-1:56 pm

1 stop7h 56m

$147

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 2/14

2:30 pm-5:20 pm

Nonstop1h 50m

Charlotte Douglas

Fri 2/20

8:25 pm-9:30 pm

Nonstop2h 05m

$148

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 2/14

2:30 pm-5:20 pm

Nonstop1h 50m

Charlotte Douglas

Mon 2/16

8:25 pm-9:30 pm

Nonstop2h 05m

$159

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 2/19

7:30 am-7:58 am

1 stop23h 28m

Charlotte Douglas

Sun 2/22

10:50 am-1:08 pm

1 stop27h 18m

$165

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Wed 1/21

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Sun 1/25

6:20 pm-7:25 pm

Nonstop2h 05m

$168

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 2/5

1:00 pm-9:30 am

1 stop19h 30m

Charlotte Douglas

Sun 2/8

11:12 am-7:52 pm

1 stop9h 40m

$175

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Fri 1/30

1:30 pm-4:20 pm

Nonstop1h 50m

Charlotte Douglas

Mon 2/2

5:50 pm-6:55 pm

Nonstop2h 05m

$177

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Sat 1/24

10:46 am-6:10 pm

1 stop6h 24m

Charlotte Douglas

Tue 1/27

2:25 pm-5:29 pm

1 stop4h 04m

$178

ChicagoCharlotte

MDW - CLT

MDWCLT

Chicago Midway

Thu 1/15

8:19 pm-8:18 am

1 stop10h 59m

Charlotte Douglas

Mon 1/19

8:48 am-3:19 pm

1 stop7h 31m

$182

ChicagoGreenville

MDW - GSP

MDWGSP

Chicago Midway

Wed 1/21

6:14 pm-11:50 pm

1 stop4h 36m

Greenville

Wed 1/28

6:50 am-9:53 am

1 stop4h 03m

$215

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Carolina from

How to get the cheapest flight ticket from Chicago Midway Airport to South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to South Carolina?

The cheapest month to fly to South Carolina from Chicago Midway Airport is in October. Flight prices, which tend to average around $249, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of October, then book flights to South Carolina from Chicago Midway Airport during May instead. Flights to South Carolina in May, while not as cheap as those in October, still average around $302.

What is the cheapest day to depart on your flight to South Carolina?

Our data shows that Tuesday is the least expensive day to fly to South Carolina. Tickets to fly out on this day can be as low as $311. The most expensive day to fly to South Carolina is Thursday, with ticket prices averaging around $491.

What is the cheapest time of day to depart on your flight to South Carolina?

Our data shows that the cheapest Chicago Midway Airport to South Carolina flights are usually those with departure times at noon. Our users have found flights to South Carolina at noon for as low as $349. Try not to purchase tickets in the morning because they tend to be around $383. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago Midway to South Carolina flight route?

Fly from Chicago Midway to Myrtle Beach Intl for the best Chicago Midway - South Carolina flight prices

What cabin class options are available on Chicago Midway to South Carolina flights?

There is only 1 cabin class available to choose from on Chicago Midway to South Carolina flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago Midway Airport to South Carolina flights?

You could potentially save up to 50% on your flight if you consider stops on a Chicago Midway Airport to South Carolina flight.

Cheap Chicago Midway Airport to South Carolina flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to South Carolina

Best Price Found

$183

Fastest flight time

1h 50m

Direct flights

Every day

Airports in South Carolina

57 airports
The best one-way flight to South Carolina from Chicago Midway Airport in the past 72 hours is $183. The best round-trip flight deal from Chicago Midway Airport to South Carolina found on momondo in the last 72 hours is $437.
The fastest flight from Chicago Midway Airport to South Carolina takes 1h 50m
Direct flights go from Chicago Midway Airport to South Carolina every day.
There are 57 airports in South Carolina. From Chicago Midway Airport there are direct flights to Myrtle Beach Intl (MYR), Charlotte Douglas (CLT).
Search flight deals

  • When did momondo last update prices for flights from Chicago Midway Airport to South Carolina?

    Prices for flights from Chicago Midway Airport to South Carolina are refreshed on a daily basis.

  • How many operators does momondo search for flights from Chicago Midway Airport to South Carolina?

  • How old do you have to be to fly from Chicago Midway Airport to South Carolina?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to South Carolina.

  • What documentation or ID do you need to fly to South Carolina?

    The travel and health documents required for your trip to South Carolina can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at South Carolina. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Chicago Midway Airport to South Carolina?

Best airlines flying from Chicago Midway Airport to South Carolina

Compare and see reviews for airlines that fly from Chicago Midway Airport to South Carolina with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $214Free CancellationRating
7.9
8,018 reviews
Search Delta flights
SouthwestPriceFrom $217Free CancellationRating
8.0
4,256 reviews
Search Southwest flights

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to South Carolina?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to South Carolina for you.

Can I find flights from Chicago to South Carolina with flexible booking policies on momondo?

All flight searches from Chicago to South Carolina on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Chicago to South Carolina?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to South Carolina from Chicago.

I’m not ready to book a flight from Chicago to South Carolina right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Carolina, momondo offers a useful price alert feature which will track prices for flights to South Carolina from Chicago and alert you when they change.

An easier way to manage your South Carolina trip

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