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Cheap flights from Chicago Midway Airport to Des Moines from $78

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Des Moines departing on 5/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago Midway Airport to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
10:05 am - 11:30 am
MDW
-
DSM
1h 25mnonstop
Southwest Logo
4:20 pm - 5:40 pm
DSM
-
MDW
1h 20mnonstop
$199Southwest
Sat, Apr 18 - Sun, Apr 19
Southwest Logo
9:50 pm - 11:15 pm
MDW
-
DSM
1h 25mnonstop
Southwest Logo
5:30 am - 6:55 am
DSM
-
MDW
1h 25mnonstop
$201Southwest
Mon, Apr 6 - Wed, Apr 8
Southwest Logo
6:00 am - 1:30 pm
MDW
-
DSM
7h 30m
1 stop
Southwest Logo
5:20 am - 6:40 am
DSM
-
MDW
1h 20mnonstop
$202Southwest
Sat, Apr 18 - Sun, Apr 19
Southwest Logo
10:15 am - 8:55 pm
MDW
-
DSM
10h 40m
2 stops
Southwest Logo
5:20 am - 6:40 am
DSM
-
MDW
1h 20mnonstop
$207Southwest
Sat, Apr 18 - Sun, Apr 19
Southwest Logo
10:00 am - 11:25 am
MDW
-
DSM
1h 25mnonstop
Southwest Logo
4:20 pm - 5:40 pm
DSM
-
MDW
1h 20mnonstop
$209Southwest
Wed, Apr 8 - Fri, Apr 10
Southwest Logo
9:45 pm - 11:05 pm
MDW
-
DSM
1h 20mnonstop
Southwest Logo
5:20 am - 6:40 am
DSM
-
MDW
1h 20mnonstop
$217Southwest
Fri, Apr 17 - Sun, Apr 19
Southwest Logo
6:30 am - 2:05 pm
MDW
-
DSM
7h 35m
1 stop
Southwest Logo
4:20 pm - 5:40 pm
DSM
-
MDW
1h 20mnonstop
$219Southwest
Wed, Apr 8 - Fri, Apr 10
Delta Logo
1:10 pm - 4:54 pm
MDW
-
DSM
3h 44m
1 stop
Delta Logo
12:29 pm - 5:54 pm
DSM
-
MDW
5h 25m
1 stop
$221Delta
Wed, Apr 8 - Sat, Apr 11
Southwest Logo
10:20 am - 11:45 am
MDW
-
DSM
1h 25mnonstop
Southwest Logo
4:20 pm - 5:40 pm
DSM
-
MDW
1h 20mnonstop
$228Southwest
Thu, Apr 9 - Mon, Apr 13
Southwest Logo
9:45 pm - 11:05 pm
MDW
-
DSM
1h 20mnonstop
Southwest Logo
5:25 am - 6:45 am
DSM
-
MDW
1h 20mnonstop
$229Southwest
Mon, Apr 20 - Thu, Apr 23

Southwest flights from Chicago Midway Airport to Des Moines

Our best Southwest deals on Chicago Midway Airport to Des Moines flight tickets
Southwest
Apr 18
MDW10:05 amChicago Midway
1h 25m
DSM11:30 amDes Moines
Apr 19
DSM4:20 pmDes Moines
1h 20m
MDW5:40 pmChicago Midway
$199
Southwest
Apr 6
MDW9:50 pmChicago Midway
1h 25m
DSM11:15 pmDes Moines
Apr 8
DSM5:30 amDes Moines
1h 25m
MDW6:55 amChicago Midway
$201
Southwest
Apr 18
MDW6:00 amChicago Midway
7h 30m
1 stop
DSM1:30 pmDes Moines
Apr 19
DSM5:20 amDes Moines
1h 20m
MDW6:40 amChicago Midway
$202

Delta flights from Chicago Midway Airport to Des Moines

Our best Delta deals on Chicago Midway Airport to Des Moines flight tickets
Delta
Apr 8
MDW1:10 pmChicago Midway
3h 44m
1 stop
DSM4:54 pmDes Moines
Apr 11
DSM12:29 pmDes Moines
5h 25m
1 stop
MDW5:54 pmChicago Midway
$221
Delta
Mar 17
MDW9:30 amChicago Midway
6h 12m
1 stop
DSM3:42 pmDes Moines
Mar 21
DSM6:15 amDes Moines
6h 14m
1 stop
MDW12:29 pmChicago Midway
$237
Delta
Apr 3
MDW1:10 pmChicago Midway
3h 44m
1 stop
DSM4:54 pmDes Moines
Apr 5
DSM6:15 amDes Moines
6h 14m
1 stop
MDW12:29 pmChicago Midway
$287

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Sat 4/18

10:05 am-11:30 am

Nonstop1h 25m

Des Moines

Sun 4/19

4:20 pm-5:40 pm

Nonstop1h 20m

$199

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Mon 4/6

9:50 pm-11:15 pm

Nonstop1h 25m

Des Moines

Wed 4/8

5:30 am-6:55 am

Nonstop1h 25m

$201

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Sat 4/18

6:00 am-1:30 pm

1 stop7h 30m

Des Moines

Sun 4/19

5:20 am-6:40 am

Nonstop1h 20m

$202

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Sat 4/18

10:15 am-8:55 pm

2 stops10h 40m

Des Moines

Sun 4/19

5:20 am-6:40 am

Nonstop1h 20m

$207

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 4/8

10:00 am-11:25 am

Nonstop1h 25m

Des Moines

Fri 4/10

4:20 pm-5:40 pm

Nonstop1h 20m

$209

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Fri 4/17

9:45 pm-11:05 pm

Nonstop1h 20m

Des Moines

Sun 4/19

5:20 am-6:40 am

Nonstop1h 20m

$217

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 4/8

6:30 am-2:05 pm

1 stop7h 35m

Des Moines

Fri 4/10

4:20 pm-5:40 pm

Nonstop1h 20m

$219

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 4/8

1:10 pm-4:54 pm

1 stop3h 44m

Des Moines

Sat 4/11

12:29 pm-5:54 pm

1 stop5h 25m

$221

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Thu 4/9

10:20 am-11:45 am

Nonstop1h 25m

Des Moines

Mon 4/13

4:20 pm-5:40 pm

Nonstop1h 20m

$228

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Mon 4/20

9:45 pm-11:05 pm

Nonstop1h 20m

Des Moines

Thu 4/23

5:25 am-6:45 am

Nonstop1h 20m

$229

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Chicago Midway Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Chicago Midway Airport to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $224. Flights from Chicago Midway Airport to Des Moines on a Tuesday will generally be more expensive and average around $466. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Chicago Midway Airport to Des Moines at noon for as low as $249. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the morning because they tend to be around $318. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Chicago Midway Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Des Moines (MDW to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Des Moines

Fastest flight time

1h 20m

Direct flights

Every day

Airports in Des Moines

1 airport
The fastest flight from Chicago Midway Airport to Des Moines takes 1h 20m
Direct flights go from Chicago Midway Airport to Des Moines every day.
There is 1 airport in Des Moines. From Chicago Midway Airport there are direct flights to Des Moines (DSM).
Search flight deals

  • How far is Chicago Midway to Des Moines by plane?

    The distance between Chicago Midway and Des Moines is about 303.6 mi. By plane, this route typically takes 1h 20m.

  • When did momondo last update prices for flights from Chicago Midway Airport to Des Moines Airport?

    Prices for flights from Chicago Midway Airport to Des Moines Airport are updated daily.

  • How old do you have to be to fly from Chicago Midway Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago Midway Airport to Des Moines?

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Urbandale
Johnston
Newton
Osceola
Boone
Grinnell
Oskaloosa
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Des Moines?

momondo helps you find the best flight between Chicago and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Chicago and alert you when they change.

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