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Cheap flights from Chicago Midway Airport to Des Moines from $97

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Des Moines departing on 8/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago Midway Airport to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Southwest Logo
9:20 pm - 10:50 pm
MDW
-
DSM
1h 30mnonstop
Southwest Logo
5:20 am - 6:40 am
DSM
-
MDW
1h 20mnonstop
$269Southwest
週三, 7月 15 - 週三, 7月 22
Southwest Logo
7:00 am - 3:05 pm
MDW
-
DSM
8h 05m
1 stop
Southwest Logo
3:45 pm - 5:05 pm
DSM
-
MDW
1h 20mnonstop
$279Southwest
週三, 7月 15 - 週三, 7月 22
Southwest Logo
10:10 am - 11:30 am
MDW
-
DSM
1h 20mnonstop
Southwest Logo
5:40 am - 7:00 am
DSM
-
MDW
1h 20mnonstop
$282Southwest
週二, 7月 21 - 週一, 8月 10
Southwest Logo
8:35 pm - 9:55 pm
MDW
-
DSM
1h 20mnonstop
Southwest Logo
7:15 am - 5:00 pm
DSM
-
MDW
9h 45m
2 stops
$284Southwest
週二, 8月 18 - 週二, 9月 1
Delta Logo
9:54 am - 2:05 pm
MDW
-
DSM
4h 11m
1 stop
Delta Logo
6:00 am - 12:38 pm
DSM
-
MDW
6h 38m
1 stop
$289Delta
週三, 7月 15 - 週三, 7月 22
Southwest Logo
3:50 pm - 9:00 pm
MDW
-
DSM
5h 10m
1 stop
Southwest Logo
7:15 am - 5:00 pm
DSM
-
MDW
9h 45m
2 stops
$294Southwest
週二, 8月 18 - 週二, 9月 1
Southwest Logo
10:05 am - 11:25 am
MDW
-
DSM
1h 20mnonstop
Southwest Logo
5:30 am - 6:45 am
DSM
-
MDW
1h 15mnonstop
$295Southwest
週四, 8月 6 - 週六, 8月 8
Southwest Logo
10:10 am - 11:30 am
MDW
-
DSM
1h 20mnonstop
Southwest Logo
4:40 pm - 6:00 pm
DSM
-
MDW
1h 20mnonstop
$299Southwest
週三, 7月 1 - 週四, 7月 2
Delta Logo
9:54 am - 2:05 pm
MDW
-
DSM
4h 11m
1 stop
Delta Logo
6:00 am - 12:39 pm
DSM
-
MDW
6h 39m
1 stop
$302Delta
週二, 7月 21 - 週一, 8月 10
Southwest Logo
10:10 am - 11:30 am
MDW
-
DSM
1h 20mnonstop
Southwest Logo
6:25 am - 1:50 pm
DSM
-
MDW
7h 25m
1 stop
$309Southwest
週三, 7月 8 - 週二, 7月 14

Southwest flights from Chicago Midway Airport to Des Moines

Our best Southwest deals on Chicago Midway Airport to Des Moines flight tickets
Southwest
Jul 15
MDW9:20 pmChicago Midway
1h 30m
DSM10:50 pmDes Moines
Jul 22
DSM5:20 amDes Moines
1h 20m
MDW6:40 amChicago Midway
$269
Southwest
Jul 15
MDW7:00 amChicago Midway
8h 05m
1 stop
DSM3:05 pmDes Moines
Jul 22
DSM3:45 pmDes Moines
1h 20m
MDW5:05 pmChicago Midway
$279
Southwest
Jul 21
MDW10:10 amChicago Midway
1h 20m
DSM11:30 amDes Moines
Aug 10
DSM5:40 amDes Moines
1h 20m
MDW7:00 amChicago Midway
$282

Delta flights from Chicago Midway Airport to Des Moines

Our best Delta deals on Chicago Midway Airport to Des Moines flight tickets
Delta
Jul 15
MDW9:54 amChicago Midway
4h 11m
1 stop
DSM2:05 pmDes Moines
Jul 22
DSM6:00 amDes Moines
6h 38m
1 stop
MDW12:38 pmChicago Midway
$289
Delta
Jul 21
MDW9:54 amChicago Midway
4h 11m
1 stop
DSM2:05 pmDes Moines
Aug 10
DSM6:00 amDes Moines
6h 39m
1 stop
MDW12:39 pmChicago Midway
$302
Delta
Jul 31
MDW9:49 amChicago Midway
4h 16m
1 stop
DSM2:05 pmDes Moines
Aug 11
DSM6:55 amDes Moines
6h 15m
1 stop
MDW1:10 pmChicago Midway
$313

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated 6月 2, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

週三 7/15

9:20 pm-10:50 pm

Nonstop1h 30m

Des Moines

週三 7/22

5:20 am-6:40 am

Nonstop1h 20m

$269

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

週三 7/15

7:00 am-3:05 pm

1 stop8h 05m

Des Moines

週三 7/22

3:45 pm-5:05 pm

Nonstop1h 20m

$279

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

週二 7/21

10:10 am-11:30 am

Nonstop1h 20m

Des Moines

週一 8/10

5:40 am-7:00 am

Nonstop1h 20m

$282

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

週二 8/18

8:35 pm-9:55 pm

Nonstop1h 20m

Des Moines

週二 9/1

7:15 am-5:00 pm

2 stops9h 45m

$284

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

週三 7/15

9:54 am-2:05 pm

1 stop4h 11m

Des Moines

週三 7/22

6:00 am-12:38 pm

1 stop6h 38m

$289

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

週二 8/18

3:50 pm-9:00 pm

1 stop5h 10m

Des Moines

週二 9/1

7:15 am-5:00 pm

2 stops9h 45m

$294
Quickest round-trip

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

週四 8/6

10:05 am-11:25 am

Nonstop1h 20m

Des Moines

週六 8/8

5:30 am-6:45 am

Nonstop1h 15m

$295

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

週三 7/1

10:10 am-11:30 am

Nonstop1h 20m

Des Moines

週四 7/2

4:40 pm-6:00 pm

Nonstop1h 20m

$299

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

週二 7/21

9:54 am-2:05 pm

1 stop4h 11m

Des Moines

週一 8/10

6:00 am-12:39 pm

1 stop6h 39m

$302

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

週三 7/8

10:10 am-11:30 am

Nonstop1h 20m

Des Moines

週二 7/14

6:25 am-1:50 pm

1 stop7h 25m

$309

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Chicago Midway Airport to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Chicago Midway Airport to Des Moines is on a Saturday. Travelers who choose to depart for Des Moines on a Saturday will often find tickets for as low as $248. Flights from Chicago Midway Airport to Des Moines on a Tuesday will generally be more expensive and average around $473. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is at noon. momondo users have found flights departing from Chicago Midway Airport to Des Moines at noon for as low as $228. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $420. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago Midway to Des Moines flight route?

Fly from Chicago Midway to Des Moines for the best Chicago Midway - Des Moines flight prices

What cabin class options are available on Chicago Midway Airport to Des Moines flights?

There is only 1 cabin class available to choose from on Chicago Midway Airport to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago Midway Airport to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Chicago Midway Airport to Des Moines.

When to book flights from Chicago Midway Airport to Des Moines

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago Midway Airport to Des Moines according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago Midway Airport to Des Moines (MDW to DSM) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Des Moines

Fastest flight time

1h 20m

Direct flights

Every day

Airports in Des Moines

1 airport
The fastest flight from Chicago Midway Airport to Des Moines takes 1h 20m
Direct flights go from Chicago Midway Airport to Des Moines every day.
There is 1 airport in Des Moines. From Chicago Midway Airport there are direct flights to Des Moines (DSM).
Search flight deals

Frequently asked questions about flying from Chicago Midway Airport to Des Moines

  • How far is Chicago Midway to Des Moines by plane?

    The distance between Chicago Midway and Des Moines is about 303.6 mi. By plane, this route typically takes 1h 20m.

  • When did momondo last update prices for flights from Chicago Midway Airport to Des Moines Airport?

    Prices for flights from Chicago Midway Airport to Des Moines Airport are updated daily.

  • How old do you have to be to fly from Chicago Midway Airport to Des Moines Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago Midway Airport to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The required travel and health documents for your Des Moines Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Des Moines Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago Midway Airport to Des Moines?

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Clive
Pella
Urbandale
Osceola
Johnston
Newton
Boone
Oskaloosa
Grinnell
Norwalk
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Des Moines?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Chicago to Des Moines. momondo saves you time and could save you money on your trip.

Can I find flights from Chicago to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Des Moines?

momondo helps you find the best flight between Chicago and Des Moines by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Chicago to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Chicago and alert you when they change.

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1 adult
週四 7/2
週四 7/9
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