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Cheap flights from Memphis to Florence from $247

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Memphis to Florence departing on 4/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Memphis to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
2:56 pm - 10:00 pm
MEM
-
FLO
6h 04m
1 stop
American Airlines Logo
5:05 am - 10:07 am
FLO
-
MEM
6h 02m
1 stop
$471American Airlines
Fri, May 22 - Tue, May 26
American Airlines Logo
2:56 pm - 10:00 pm
MEM
-
FLO
6h 04m
1 stop
American Airlines Logo
2:35 pm - 11:59 pm
FLO
-
MEM
10h 24m
2 stops
$476American Airlines
Fri, May 22 - Tue, May 26
American Airlines Logo
2:56 pm - 10:00 pm
MEM
-
FLO
6h 04m
1 stop
American Airlines Logo
5:05 am - 10:07 am
FLO
-
MEM
6h 02m
1 stop
$491American Airlines
Fri, May 22 - Tue, May 26
American Airlines Logo
3:23 pm - 9:47 pm
MEM
-
FLO
5h 24m
1 stop
American Airlines Logo
5:20 am - 8:18 am
FLO
-
MEM
3h 58m
1 stop
$495American Airlines
Thu, Apr 16 - Sun, Apr 19
American Airlines Logo
2:56 pm - 10:00 pm
MEM
-
FLO
6h 04m
1 stop
American Airlines Logo
2:35 pm - 11:59 pm
FLO
-
MEM
10h 24m
2 stops
$496American Airlines
Fri, May 22 - Tue, May 26
American Airlines Logo
3:23 pm - 9:47 pm
MEM
-
FLO
5h 24m
1 stop
American Airlines Logo
4:16 pm - 11:42 pm
FLO
-
MEM
8h 26m
2 stops
$500American Airlines
Fri, Apr 17 - Mon, Apr 20
American Airlines Logo
6:40 am - 9:47 pm
MEM
-
FLO
14h 07m
2 stops
American Airlines Logo
4:16 pm - 7:47 pm
FLO
-
MEM
4h 31m
1 stop
$529American Airlines
Thu, Apr 16 - Sun, Apr 19
American Airlines Logo
3:23 pm - 9:47 pm
MEM
-
FLO
5h 24m
1 stop
American Airlines Logo
4:16 pm - 11:42 pm
FLO
-
MEM
8h 26m
2 stops
$541American Airlines
Fri, Apr 24 - Sun, Apr 26
American Airlines Logo
6:08 pm - 11:57 pm
MEM
-
FLO
4h 49m
1 stop
American Airlines Logo
6:15 am - 9:52 am
FLO
-
MEM
4h 37m
1 stop
$542American Airlines
Fri, Mar 27 - Tue, Mar 31
American Airlines Logo
5:45 am - 5:50 pm
MEM
-
FLO
11h 05m
2 stops
American Airlines Logo
6:15 am - 9:52 am
FLO
-
MEM
4h 37m
1 stop
$547American Airlines
Fri, Mar 27 - Tue, Mar 31

American Airlines flights from Memphis to Florence, South Carolina

Our best American Airlines deals on Memphis to Florence, South Carolina flight tickets
American Airlines
May 22
MEM2:56 pmMemphis
6h 04m
1 stop
FLO10:00 pmFlorence
May 26
FLO5:05 amFlorence
6h 02m
1 stop
MEM10:07 amMemphis
$471
American Airlines
May 22
MEM2:56 pmMemphis
6h 04m
1 stop
FLO10:00 pmFlorence
May 26
FLO2:35 pmFlorence
10h 24m
2 stops
MEM11:59 pmMemphis
$476
American Airlines
May 22
MEM2:56 pmMemphis
6h 04m
1 stop
FLO10:00 pmFlorence
May 26
FLO5:05 amFlorence
6h 02m
1 stop
MEM10:07 amMemphis
$491

momondo Fare Finder

 
Customize your flight search to find flights from Memphis to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Memphis to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 5/22

2:56 pm-10:00 pm

1 stop6h 04m

Florence

Tue 5/26

5:05 am-10:07 am

1 stop6h 02m

$471

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 5/22

2:56 pm-10:00 pm

1 stop6h 04m

Florence

Tue 5/26

2:35 pm-11:59 pm

2 stops10h 24m

$476

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 5/22

2:56 pm-10:00 pm

1 stop6h 04m

Florence

Tue 5/26

5:05 am-10:07 am

1 stop6h 02m

$491
Quickest round-trip

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Thu 4/16

3:23 pm-9:47 pm

1 stop5h 24m

Florence

Sun 4/19

5:20 am-8:18 am

1 stop3h 58m

$495

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 5/22

2:56 pm-10:00 pm

1 stop6h 04m

Florence

Tue 5/26

2:35 pm-11:59 pm

2 stops10h 24m

$496

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 4/17

3:23 pm-9:47 pm

1 stop5h 24m

Florence

Mon 4/20

4:16 pm-11:42 pm

2 stops8h 26m

$500

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Thu 4/16

6:40 am-9:47 pm

2 stops14h 07m

Florence

Sun 4/19

4:16 pm-7:47 pm

1 stop4h 31m

$529

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 4/24

3:23 pm-9:47 pm

1 stop5h 24m

Florence

Sun 4/26

4:16 pm-11:42 pm

2 stops8h 26m

$541

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 3/27

6:08 pm-11:57 pm

1 stop4h 49m

Florence

Tue 3/31

6:15 am-9:52 am

1 stop4h 37m

$542

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 3/27

5:45 am-5:50 pm

2 stops11h 05m

Florence

Tue 3/31

6:15 am-9:52 am

1 stop4h 37m

$547

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
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See travel insights to Florence from

How to get the cheapest flight ticket from Memphis to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Memphis to Florence?

American Airlines is the most popular carrier operating from Memphis to Florence

What airlines fly to Florence, South Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Florence, South Carolina from Memphis according to our data. American Airlines is the first choice among our users, with 58% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 4 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Memphis to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Memphis to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Memphis to Florence, South Carolina (MEM to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Memphis to Florence, South Carolina

Fastest flight time

5h 24m

Direct flights

None
The fastest flight from Memphis to Florence, South Carolina takes 5h 24m
There are no direct flights from Memphis to Florence, South Carolina. There are no popular flight routes from Memphis to Florence, South Carolina.
Search flight deals

  • How far is Memphis to Florence by plane?

    Memphis and Florence are 587.5 mi apart from one another. In terms of flight time, this usually takes a little over 5h 24m.

  • When did momondo last update prices for flights from Memphis Airport to Florence Airport?

    Prices for flights from Memphis Airport to Florence Airport refresh daily.

  • How old do you have to be to fly from Memphis Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Memphis Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Lake City
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Memphis to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Memphis.

Can I find flights from Memphis to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Memphis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Memphis to Florence?

Once all potential Memphis to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Memphis to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Memphis to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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