Cheap flights from Memphis to Florence from $387

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Memphis to Florence departing on 10/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

American Airlines Logo
9:48 am - 5:12 pmMEM-FLO
6h 24m1 stop
American Airlines Logo
2:29 pm - 6:06 pmFLO-MEM
4h 37m1 stop
$387American Airlines
Find Deal
Sat, Oct 4 - Sat, Oct 11
American Airlines Logo
5:00 am - 12:26 pmMEM-FLO
6h 26m1 stop
American Airlines Logo
6:32 pm - 11:56 pmFLO-MEM
6h 24m1 stop
$435American Airlines
Find Deal
Mon, Dec 22 - Fri, Jan 2
American Airlines Logo
6:08 pm - 11:16 pmMEM-FLO
4h 08m1 stop
American Airlines Logo
2:29 pm - 11:59 pmFLO-MEM
10h 30m2 stops
$441American Airlines
Find Deal
Sat, Oct 4 - Sat, Oct 11
American Airlines Logo
6:08 pm - 11:16 pmMEM-FLO
4h 08m1 stop
American Airlines Logo
6:14 am - 11:55 amFLO-MEM
6h 41m1 stop
$442American Airlines
Find Deal
Fri, Sep 19 - Tue, Sep 23
American Airlines Logo
5:00 am - 12:26 pmMEM-FLO
6h 26m1 stop
American Airlines Logo
6:32 pm - 11:56 pmFLO-MEM
6h 24m1 stop
$475American Airlines
Find Deal
Mon, Dec 22 - Sun, Jan 4
American Airlines Logo
9:37 am - 11:16 pmMEM-FLO
12h 39m2 stops
American Airlines Logo
2:29 pm - 11:59 pmFLO-MEM
10h 30m2 stops
$523American Airlines
Find Deal
Sat, Oct 4 - Sat, Oct 11
American Airlines Logo
10:11 am - 5:12 pmMEM-FLO
6h 01m1 stop
American Airlines Logo
6:14 am - 4:48 pmFLO-MEM
11h 34m2 stops
$524American Airlines
Find Deal
Fri, Sep 19 - Tue, Sep 23
American Airlines Logo
5:00 am - 12:26 pmMEM-FLO
6h 26m1 stop
American Airlines Logo
5:15 am - 3:20 pmFLO-MEM
11h 05m2 stops
$549American Airlines
Find Deal
Mon, Dec 22 - Fri, Jan 2
American Airlines Logo
5:00 am - 12:26 pmMEM-FLO
6h 26m1 stop
American Airlines Logo
5:15 am - 8:47 amFLO-MEM
4h 32m1 stop
$576American Airlines
Find Deal
Mon, Dec 22 - Sun, Jan 4
American Airlines Logo
6:00 am - 5:12 pmMEM-FLO
10h 12m2 stops
American Airlines Logo
6:14 am - 5:21 pmFLO-MEM
12h 07m2 stops
$581American Airlines
Find Deal
Fri, Sep 19 - Tue, Sep 23

American Airlines flights from Memphis to Florence, South Carolina

Our best American Airlines deals on Memphis to Florence, South Carolina flight tickets
American Airlines
Oct 4
MEM9:48 amMemphis
6h 24m
1 stop
FLO5:12 pmFlorence
Oct 11
FLO2:29 pmFlorence
4h 37m
1 stop
MEM6:06 pmMemphis
American Airlines
Dec 22
MEM5:00 amMemphis
6h 26m
1 stop
FLO12:26 pmFlorence
Jan 2
FLO6:32 pmFlorence
6h 24m
1 stop
MEM11:56 pmMemphis
American Airlines
Oct 4
MEM6:08 pmMemphis
4h 08m
1 stop
FLO11:16 pmFlorence
Oct 11
FLO2:29 pmFlorence
10h 30m
2 stops
MEM11:59 pmMemphis

momondo Fare Finder

 
Customize your flight search to find flights from Memphis to Florence, South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Memphis to Florence, South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Sat 10/4

9:48 am-5:12 pm

1 stop6h 24m

Florence

Sat 10/11

2:29 pm-6:06 pm

1 stop4h 37m

$387

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Mon 12/22

5:00 am-12:26 pm

1 stop6h 26m

Florence

Fri 1/2

6:32 pm-11:56 pm

1 stop6h 24m

$435

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Sat 10/4

6:08 pm-11:16 pm

1 stop4h 08m

Florence

Sat 10/11

2:29 pm-11:59 pm

2 stops10h 30m

$441

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 9/19

6:08 pm-11:16 pm

1 stop4h 08m

Florence

Tue 9/23

6:14 am-11:55 am

1 stop6h 41m

$442

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Mon 12/22

5:00 am-12:26 pm

1 stop6h 26m

Florence

Sun 1/4

6:32 pm-11:56 pm

1 stop6h 24m

$475

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Sat 10/4

9:37 am-11:16 pm

2 stops12h 39m

Florence

Sat 10/11

2:29 pm-11:59 pm

2 stops10h 30m

$523

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 9/19

10:11 am-5:12 pm

1 stop6h 01m

Florence

Tue 9/23

6:14 am-4:48 pm

2 stops11h 34m

$524

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Mon 12/22

5:00 am-12:26 pm

1 stop6h 26m

Florence

Fri 1/2

5:15 am-3:20 pm

2 stops11h 05m

$549

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Mon 12/22

5:00 am-12:26 pm

1 stop6h 26m

Florence

Sun 1/4

5:15 am-8:47 am

1 stop4h 32m

$576

MemphisFlorence

MEM - FLO

MEMFLO

Memphis

Fri 9/19

6:00 am-5:12 pm

2 stops10h 12m

Florence

Tue 9/23

6:14 am-5:21 pm

2 stops12h 07m

$581

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Florence from

How to get the cheapest flight ticket from Memphis to Florence, South Carolina

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What airlines fly to Florence, South Carolina?

American Airlines, Delta and Southwest are the top three most popular airlines that fly to Florence, South Carolina from Memphis according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Florence, South Carolina. Keep in mind that there are 4 different airlines that fly to Florence, South Carolina on a routine basis, so you have a few additional options to choose from.

When to book flights from Memphis to Florence, South Carolina

Are you open to changing your travel dates? Check out the ideal times to fly from Memphis to Florence, South Carolina according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Memphis to Florence, South Carolina (MEM to FLO) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Memphis to Florence, South Carolina

Direct flights

None
There are no direct flights from Memphis to Florence, South Carolina. There are no popular flight routes from Memphis to Florence, South Carolina.
  • How far is Memphis to Florence by plane?

    Memphis and Florence are 587.5 mi apart from one another. In terms of flight time, this usually takes a little over 4h 08m.

  • When did momondo last update prices for flights from Memphis Airport to Florence Airport?

    Prices for flights from Memphis Airport to Florence Airport refresh daily.

  • How old do you have to be to fly from Memphis Airport to Florence Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Memphis Airport to Florence Airport.

  • What documentation or ID do you need to fly to Florence Airport?

    The necessary travel and health documents for your Florence Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Lake City
Hartsville
Bennettsville
Darlington

Why use momondo?

Why should I use momondo to find a flight deal from Memphis to Florence?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Florence from Memphis.

Can I find flights from Memphis to Florence with flexible booking policies on momondo?

momondo does allow users to show only those flights to Florence from Memphis which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Memphis to Florence?

Once all potential Memphis to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Memphis to Florence right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Memphis to Florence flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Tue 9/2
Tue 9/9

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