When did momondo last update prices for flights from Medford Airport to Knoxville McGhee Tyson Airport?

Prices for flights from Medford Airport to Knoxville McGhee Tyson Airport were last updated today.

How many operators does momondo search for flights from Medford Airport to Knoxville McGhee Tyson Airport?

As of November 2025, there is 1 operator available to choose from for flights from Medford Airport to Knoxville McGhee Tyson Airport.

How old do you have to be to fly from Medford Airport to Knoxville McGhee Tyson Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Medford Airport to Knoxville McGhee Tyson Airport.

What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$269 Cheap Flights from Medford to Knoxville in 2025/26

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Find the cheapest flights from Medford to Knoxville

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6:05 am - 8:47 pmMFR-TYS

11h 42m2 stops

5:30 am - 12:20 pmTYS-MFR

9h 50m2 stops

$319Delta

Find Deal

Tue, Feb 24 - Sat, Feb 28

5:00 am - 3:14 pmMFR-TYS

7h 14m1 stop

9:30 am - 5:52 pmTYS-MFR

11h 22m2 stops

$485United Airlines

Find Deal

Thu, Jan 8 - Sat, Jan 17

5:02 am - 7:29 pmMFR-TYS

11h 27m2 stops

4:15 pm - 9:18 pmTYS-MFR

8h 03m1 stop

$533United Airlines

Find Deal

Tue, Feb 24 - Sat, Feb 28

5:02 am - 3:05 pmMFR-TYS

7h 03m1 stop

4:15 pm - 9:18 pmTYS-MFR

8h 03m1 stop

$599United Airlines

Find Deal

Tue, Feb 24 - Sat, Feb 28

5:00 am - 3:51 pmMFR-TYS

7h 51m1 stop

4:55 pm - 1:23 pmTYS-MFR

23h 28m1 stop

$698United Airlines

Find Deal

Mon, Nov 17 - Fri, Nov 21

6:36 pm - 10:48 amMFR-TYS

13h 12m2 stops

4:55 pm - 1:23 pmTYS-MFR

23h 28m1 stop

$703United Airlines

Find Deal

Mon, Nov 17 - Fri, Nov 21

6:36 pm - 10:48 amMFR-TYS

13h 12m2 stops

4:55 pm - 8:08 pmTYS-MFR

30h 13m2 stops

$817United Airlines

Find Deal

Mon, Nov 17 - Fri, Nov 21

5:00 am - 11:59 pmMFR-TYS

15h 59m2 stops

4:55 pm - 1:23 pmTYS-MFR

23h 28m1 stop

$1,287United Airlines

Find Deal

Tue, Nov 25 - Sun, Nov 30

6:07 pm - 8:34 amMFR-TYS

11h 27m2 stops

5:10 am - 1:00 pmTYS-MFR

10h 50m2 stops

$1,420American Airlines

Find Deal

Tue, Nov 25 - Sun, Nov 30

8:00 am - 11:52 pmMFR-TYS

12h 52m2 stops

5:10 am - 1:00 pmTYS-MFR

10h 50m2 stops

$1,629American Airlines

Find Deal

Tue, Nov 25 - Sun, Nov 30

Delta flights from Medford to Knoxville

Our best Delta deals on Medford to Knoxville flight tickets

Delta

Feb 24

MFR6:05 amMedford

11h 42m

2 stops

TYS8:47 pmKnoxville McGhee Tyson

Feb 28

TYS5:30 amKnoxville McGhee Tyson

9h 50m

2 stops

MFR12:20 pmMedford

$319

Find similar

Delta

Nov 11

MFR5:23 pmMedford

13h 14m

2 stops

TYS9:37 amKnoxville McGhee Tyson

Nov 18

TYS2:41 pmKnoxville McGhee Tyson

12h 15m

2 stops

MFR11:56 pmMedford

$495

Find similar

Delta

Nov 10

MFR5:00 amMedford

11h 02m

2 stops

TYS7:02 pmKnoxville McGhee Tyson

Nov 17

TYS3:53 pmKnoxville McGhee Tyson

10h 39m

2 stops

MFR11:32 pmMedford

$539

Find similar

United Airlines flights from Medford to Knoxville

Our best United Airlines deals on Medford to Knoxville flight tickets

United Airlines

Jan 8

MFR5:00 amMedford

7h 14m

1 stop

TYS3:14 pmKnoxville McGhee Tyson

Jan 17

TYS9:30 amKnoxville McGhee Tyson

11h 22m

2 stops

MFR5:52 pmMedford

$485

Find similar

United Airlines

Nov 11

MFR5:00 amMedford

6h 43m

1 stop

TYS2:43 pmKnoxville McGhee Tyson

Nov 18

TYS8:26 amKnoxville McGhee Tyson

12h 26m

2 stops

MFR5:52 pmMedford

$490

Find similar

United Airlines

Feb 24

MFR5:02 amMedford

11h 27m

2 stops

TYS7:29 pmKnoxville McGhee Tyson

Feb 28

TYS4:15 pmKnoxville McGhee Tyson

8h 03m

1 stop

MFR9:18 pmMedford

$533

Find similar

Fly from

Fly to

Route

Depart

Return

Price

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Tue 2/24

6:05 am-8:47 pm

2 stops11h 42m

Knoxville McGhee Tyson

Sat 2/28

5:30 am-12:20 pm

2 stops9h 50m

$319

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Thu 1/8

5:00 am-3:14 pm

1 stop7h 14m

Knoxville McGhee Tyson

Sat 1/17

9:30 am-5:52 pm

2 stops11h 22m

$485

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Tue 2/24

5:02 am-7:29 pm

2 stops11h 27m

Knoxville McGhee Tyson

Sat 2/28

4:15 pm-9:18 pm

1 stop8h 03m

$533

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Tue 2/24

5:02 am-3:05 pm

1 stop7h 03m

Knoxville McGhee Tyson

Sat 2/28

4:15 pm-9:18 pm

1 stop8h 03m

$599

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Mon 11/17

5:00 am-3:51 pm

1 stop7h 51m

Knoxville McGhee Tyson

Fri 11/21

4:55 pm-1:23 pm

1 stop23h 28m

$698

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Mon 11/17

6:36 pm-10:48 am

2 stops13h 12m

Knoxville McGhee Tyson

Fri 11/21

4:55 pm-1:23 pm

1 stop23h 28m

$703

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Mon 11/17

6:36 pm-10:48 am

2 stops13h 12m

Knoxville McGhee Tyson

Fri 11/21

4:55 pm-8:08 pm

2 stops30h 13m

$817

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Tue 11/25

5:00 am-11:59 pm

2 stops15h 59m

Knoxville McGhee Tyson

Sun 11/30

4:55 pm-1:23 pm

1 stop23h 28m

$1,287

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Tue 11/25

6:07 pm-8:34 am

2 stops11h 27m

Knoxville McGhee Tyson

Sun 11/30

5:10 am-1:00 pm

2 stops10h 50m

$1,420

MedfordKnoxville

MFR - TYS

MFRTYS

Medford

Tue 11/25

8:00 am-11:52 pm

2 stops12h 52m

Knoxville McGhee Tyson

Sun 11/30

5:10 am-1:00 pm

2 stops10h 50m

$1,629

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Medford to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of December is, on average, the cheapest month to fly to Knoxville from Medford, with most prices found around $454. If you aren’t able to travel during the month of December, then book flights to Knoxville from Medford during October instead. Flights to Knoxville in October, while not as cheap as those in December, still average around $458.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Medford to Knoxville is on a Tuesday. Travelers who choose to depart for Knoxville on a Tuesday will often find tickets for as low as $518. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Medford to Knoxville for around $921.

What is the cheapest time of day to depart on your flight to Knoxville?

In the morning is the cheapest time of day to fly from Medford to Knoxville when you can find flight prices for as low as $582. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the afternoon when prices are around $603.

When to book flights from Medford to Knoxville

Are you open to changing your travel dates? Check out the ideal times to fly from Medford to Knoxville according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Medford to Knoxville (MFR to TYS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Medford to Knoxville

Direct flights	None

There are no direct flights from Medford to Knoxville. There are no popular flight routes from Medford to Knoxville.

Search flight deals

How far is Medford to Knoxville McGhee Tyson by plane?
Medford and Knoxville McGhee Tyson are 2112.6 mi apart from one another. Typically, this will take 7h 03m by plane in normal conditions.
When did momondo last update prices for flights from Medford Airport to Knoxville McGhee Tyson Airport?
Prices for flights from Medford Airport to Knoxville McGhee Tyson Airport were last updated today.
How many operators does momondo search for flights from Medford Airport to Knoxville McGhee Tyson Airport?
As of November 2025, there is 1 operator available to choose from for flights from Medford Airport to Knoxville McGhee Tyson Airport.
How old do you have to be to fly from Medford Airport to Knoxville McGhee Tyson Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Medford Airport to Knoxville McGhee Tyson Airport.
What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?
The required travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Knoxville McGhee Tyson Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Medford to Knoxville?
momondo data reveals that the most frequently booked airline on the route from Medford to Knoxville is United Airlines, representing 100% of all bookings.

Best airlines flying from Medford to Knoxville

Compare and see reviews for airlines that fly from Medford to Knoxville with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $348	Free Cancellation	Rating 7.4 9,007 reviews		Search United Airlines flights

Pigeon Forge

Gatlinburg

Cherokee

Bryson City

Morristown

Corbin

Crossville

Maryville

Murphy

Alcoa

Oak Ridge

Newport

Lenoir City

Kodak

Dandridge

Clinton

Jefferson City

Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Medford to Knoxville?

Finding the right flight to Knoxville from Medford is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Knoxville quick and easy, saving you time and money.

Can I find flights from Medford to Knoxville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Knoxville from Medford with this policy.

How can momondo help me find flights from Medford to Knoxville?

momondo helps you find the best flight between Medford and Knoxville by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Medford to Knoxville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Knoxville from Medford. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.