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Cheap flights from Massachusetts to Knoxville from $66

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Massachusetts to Knoxville departing on 12/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Massachusetts to Knoxville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
9:29 am - 12:12 pmBOS-TYS
2h 43mnonstop
Allegiant Air Logo
6:30 am - 8:39 amTYS-BOS
2h 09mnonstop
$141Allegiant Air
Find Deal
Thu, Feb 12 - Sun, Feb 15
Multiple Airlines Logo
11:28 am - 8:33 amBOS-TYS
21h 05m2 stops
Multiple Airlines Logo
6:00 am - 8:10 amTYS-BOS
2h 10mnonstop
$177Multiple Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
Multiple Airlines Logo
8:11 pm - 9:49 pmBOS-TYS
25h 38m1 stop
Multiple Airlines Logo
6:00 am - 8:10 amTYS-BOS
2h 10mnonstop
$180Multiple Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
Multiple Airlines Logo
11:28 am - 8:33 amBOS-TYS
21h 05m2 stops
Multiple Airlines Logo
6:00 am - 8:10 amTYS-BOS
2h 10mnonstop
$181Multiple Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
Multiple Airlines Logo
8:11 pm - 9:49 pmBOS-TYS
25h 38m1 stop
Multiple Airlines Logo
6:00 am - 8:10 amTYS-BOS
2h 10mnonstop
$182Multiple Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
American Airlines Logo
4:14 pm - 10:54 pmBDL-TYS
6h 40m1 stop
American Airlines Logo
8:09 am - 12:34 pmTYS-BDL
4h 25m1 stop
$201American Airlines
Find Deal
Tue, Jan 27 - Sat, Jan 31
American Airlines Logo
5:00 am - 1:54 pmBDL-TYS
8h 54m2 stops
American Airlines Logo
3:00 pm - 7:59 pmTYS-BDL
4h 59m1 stop
$206American Airlines
Find Deal
Tue, Jan 27 - Sat, Jan 31
Delta Logo
7:05 pm - 11:44 pmBDL-TYS
4h 39m1 stop
Delta Logo
12:00 pm - 4:05 pmTYS-BDL
4h 05m1 stop
$299Delta
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Mon, Apr 6 - Thu, Apr 9
Delta Logo
7:05 am - 12:50 pmALB-TYS
5h 45m1 stop
Delta Logo
7:30 am - 11:51 amTYS-ALB
4h 21m1 stop
$301Delta
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Sat, Mar 7 - Wed, Mar 11
United Airlines Logo
6:00 am - 1:17 pmALB-TYS
7h 17m1 stop
United Airlines Logo
9:40 am - 2:13 pmTYS-ALB
4h 33m1 stop
$337United Airlines
Find Deal
Tue, Dec 2 - Sat, Dec 6

Delta flights from Massachusetts to Knoxville

Our best Delta deals on Massachusetts to Knoxville flight tickets
Delta
Jan 13
BOS5:29 amBoston Logan Intl
6h 44m
1 stop
TYS12:13 pmKnoxville McGhee Tyson
Jan 17
TYS1:05 pmKnoxville McGhee Tyson
5h 22m
1 stop
BOS6:27 pmBoston Logan Intl
$231
Find similar
Delta
Nov 24
BOS2:00 pmBoston Logan Intl
6h 35m
1 stop
TYS8:35 pmKnoxville McGhee Tyson
Nov 27
TYS2:49 pmKnoxville McGhee Tyson
4h 48m
1 stop
BOS7:37 pmBoston Logan Intl
$279
Find similar
Delta
Apr 6
BDL7:05 pmHartford Bradley Intl
4h 39m
1 stop
TYS11:44 pmKnoxville McGhee Tyson
Apr 9
TYS12:00 pmKnoxville McGhee Tyson
4h 05m
1 stop
BDL4:05 pmHartford Bradley Intl
$299
Find similar

Southwest flights from Massachusetts to Knoxville

Our best Southwest deals on Massachusetts to Knoxville flight tickets
Southwest
May 1
BDL11:20 amHartford Bradley Intl
9h 55m
2 stops
TYS9:15 pmKnoxville McGhee Tyson
May 5
TYS8:15 amKnoxville McGhee Tyson
3h 55m
1 stop
BDL12:10 pmHartford Bradley Intl
$364
Find similar
Southwest
Mar 28
ALB10:25 amAlbany Intl
10h 40m
1 stop
TYS9:05 pmKnoxville McGhee Tyson
Mar 30
TYS7:50 amKnoxville McGhee Tyson
8h 50m
1 stop
ALB4:40 pmAlbany Intl
$367
Find similar
Southwest
May 1
BDL11:20 amHartford Bradley Intl
9h 55m
2 stops
TYS9:15 pmKnoxville McGhee Tyson
May 5
TYS7:05 amKnoxville McGhee Tyson
7h 35m
2 stops
BDL2:40 pmHartford Bradley Intl
$374
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Massachusetts to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 19, 2025.
Use the filters below to find and compare flights from Massachusetts to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 2/12

9:29 am-12:12 pm

Nonstop2h 43m

Knoxville McGhee Tyson

Sun 2/15

6:30 am-8:39 am

Nonstop2h 09m

$141

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 12/4

11:28 am-8:33 am

2 stops21h 05m

Knoxville McGhee Tyson

Sun 12/7

6:00 am-8:10 am

Nonstop2h 10m

$177

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 12/4

8:11 pm-9:49 pm

1 stop25h 38m

Knoxville McGhee Tyson

Sun 12/7

6:00 am-8:10 am

Nonstop2h 10m

$180

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 12/4

11:28 am-8:33 am

2 stops21h 05m

Knoxville McGhee Tyson

Sun 12/7

6:00 am-8:10 am

Nonstop2h 10m

$181

BostonKnoxville

BOS - TYS

BOSTYS

Boston Logan Intl

Thu 12/4

8:11 pm-9:49 pm

1 stop25h 38m

Knoxville McGhee Tyson

Sun 12/7

6:00 am-8:10 am

Nonstop2h 10m

$182

HartfordKnoxville

BDL - TYS

BDLTYS

Hartford Bradley Intl

Tue 1/27

4:14 pm-10:54 pm

1 stop6h 40m

Knoxville McGhee Tyson

Sat 1/31

8:09 am-12:34 pm

1 stop4h 25m

$201

HartfordKnoxville

BDL - TYS

BDLTYS

Hartford Bradley Intl

Tue 1/27

5:00 am-1:54 pm

2 stops8h 54m

Knoxville McGhee Tyson

Sat 1/31

3:00 pm-7:59 pm

1 stop4h 59m

$206

HartfordKnoxville

BDL - TYS

BDLTYS

Hartford Bradley Intl

Mon 4/6

7:05 pm-11:44 pm

1 stop4h 39m

Knoxville McGhee Tyson

Thu 4/9

12:00 pm-4:05 pm

1 stop4h 05m

$299

AlbanyKnoxville

ALB - TYS

ALBTYS

Albany Intl

Sat 3/7

7:05 am-12:50 pm

1 stop5h 45m

Knoxville McGhee Tyson

Wed 3/11

7:30 am-11:51 am

1 stop4h 21m

$301

AlbanyKnoxville

ALB - TYS

ALBTYS

Albany Intl

Tue 12/2

6:00 am-1:17 pm

1 stop7h 17m

Knoxville McGhee Tyson

Sat 12/6

9:40 am-2:13 pm

1 stop4h 33m

$337

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Knoxville from

How to get the cheapest flight ticket from Massachusetts to Knoxville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Knoxville?

The month of February is, on average, the cheapest month to fly to Knoxville from Massachusetts, with most prices found around $152. If you aren’t able to travel during the month of February, then book flights to Knoxville from Massachusetts during July instead. Flights to Knoxville in July, while not as cheap as those in February, still average around $188.

What is the cheapest day to depart on your flight to Knoxville?

The cheapest day to depart from Massachusetts to Knoxville is on a Wednesday. Travelers who choose to depart for Knoxville on a Wednesday will often find tickets for as low as $127. When flying out on a Tuesday, the most expensive travel day of the week, you can expect to see flight prices from Massachusetts to Knoxville for around $218.

What is the cheapest time of day to depart on your flight to Knoxville?

In the morning is the cheapest time of day to fly from Massachusetts to Knoxville when you can find flight prices for as low as $194. Flying to Knoxville in the morning is an ideal time because this is during off-peak travel hours. In contrast, the most expensive time of day to depart to Knoxville is in the evening when prices are around $604.

What is the cheapest Massachusetts to Knoxville McGhee Tyson flight route?

Fly from Boston Logan Intl to Knoxville McGhee Tyson for the best Massachusetts - Knoxville McGhee Tyson flight prices

How far in advance should I book a flight to Knoxville?

You are more likely to see cheaper flights to Knoxville from Massachusetts when booking weeks ahead of your departure date. In general, you can expect to find flights to Knoxville for around $304 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Knoxville from Massachusetts for as low as $214 on momondo.

What cabin class options are available on Massachusetts to Knoxville McGhee Tyson flights?

There is only 1 cabin class available to choose from on Massachusetts to Knoxville McGhee Tyson flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Massachusetts to Knoxville flights?

No. A direct flight is the cheapest option for a flight between Massachusetts to Knoxville.

Cheap Massachusetts to Knoxville flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Massachusetts to Knoxville

Best Price Found

$109

Fastest flight time

2h 29m

Direct flights

Mon, Tue, Wed, Fri and Sun

Airports in Knoxville

1 airport
The best one-way flight to Knoxville from Massachusetts in the past 72 hours is $109. The best round-trip flight deal from Massachusetts to Knoxville found on momondo in the last 72 hours is $144.
The fastest flight from Massachusetts to Knoxville takes 2h 29m
Direct flights go from Massachusetts to Knoxville on Monday, Tuesday, Wednesday, Friday and Sunday. The only airline offering direct flights is Allegiant Air.
There is 1 airport near Knoxville: Knoxville McGhee Tyson (TYS)
Search flight deals

  • When did momondo last update prices for flights from Massachusetts to Knoxville McGhee Tyson Airport?

    Prices for flights from Massachusetts to Knoxville McGhee Tyson Airport refresh daily.

  • How many operators does momondo search for flights from Massachusetts to Knoxville McGhee Tyson Airport?

  • How old do you have to be to fly from Massachusetts to Knoxville McGhee Tyson Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Massachusetts to Knoxville McGhee Tyson Airport.

  • What documentation or ID do you need to fly to Knoxville McGhee Tyson Airport?

    The necessary travel and health documents for your Knoxville McGhee Tyson Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Massachusetts to Knoxville?

Best airlines flying from Massachusetts to Knoxville

Compare and see reviews for airlines that fly from Massachusetts to Knoxville with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $89Free CancellationRating
7.2
700 reviews
Search Allegiant Air flights
DeltaPriceFrom $215Free CancellationRating
7.9
8,004 reviews
Search Delta flights
American AirlinesPriceFrom $248Free CancellationRating
7.2
11,046 reviews
Search American Airlines flights
United AirlinesPriceFrom $318Free CancellationRating
7.4
9,025 reviews
Search United Airlines flights

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Pigeon Forge
Gatlinburg
Cherokee
Bryson City
Morristown
Corbin
Crossville
Maryville
Murphy
Alcoa
Oak Ridge
Newport
Lenoir City
Kodak
Dandridge
Clinton
Jefferson City
Rockford

Why use momondo?

Why should I use momondo to find a flight deal from Massachusetts to Knoxville?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Knoxville from Massachusetts.

Can I find flights from Massachusetts to Knoxville with flexible booking policies on momondo?

Yes. All flights to Knoxville from Massachusetts on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Massachusetts to Knoxville?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Knoxville from Massachusetts.

I’m not ready to book a flight from Massachusetts to Knoxville right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Knoxville, momondo offers a useful price alert feature which will track prices for flights to Knoxville from Massachusetts and alert you when they change.

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