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Cheap flights from Massachusetts to Des Moines from $109

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Massachusetts to Des Moines departing on 3/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Massachusetts to Des Moines

Cheap round-trip flights

Enter your travel dates to find the best prices.
Allegiant Air Logo
12:45 pm - 2:58 pm
BOS
-
DSM
3h 13mnonstop
Allegiant Air Logo
8:00 am - 11:55 am
DSM
-
BOS
2h 55mnonstop
$126Allegiant Air
Fri, Jan 2 - Mon, Jan 5
Multiple Airlines Logo
12:45 pm - 2:58 pm
BOS
-
DSM
3h 13mnonstop
Multiple Airlines Logo
2:58 pm - 1:19 am
DSM
-
BOS
33h 21m2 stops
$194Multiple Airlines
Mon, Jan 5 - Sun, Jan 11
Multiple Airlines Logo
12:45 pm - 2:58 pm
BOS
-
DSM
3h 13mnonstop
Multiple Airlines Logo
4:30 pm - 5:44 pm
DSM
-
BOS
48h 14m3 stops
$205Multiple Airlines
Mon, Jan 5 - Sun, Jan 11
Multiple Airlines Logo
12:45 pm - 2:58 pm
BOS
-
DSM
3h 13mnonstop
Multiple Airlines Logo
2:58 pm - 12:49 pm
DSM
-
BOS
20h 51m1 stop
$230Multiple Airlines
Mon, Jan 5 - Thu, Jan 8
Delta Logo
5:40 am - 11:24 am
BDL
-
DSM
6h 44m1 stop
Delta Logo
6:24 am - 12:02 pm
DSM
-
BDL
4h 38m1 stop
$308Delta
Wed, Jan 14 - Sat, Jan 17
Delta Logo
6:04 am - 10:19 am
BDL
-
DSM
5h 15m1 stop
Delta Logo
5:49 pm - 11:40 pm
DSM
-
BDL
4h 51m1 stop
$320Delta
Sun, Jan 18 - Mon, Jan 19
United Airlines Logo
3:30 pm - 11:44 pm
BDL
-
DSM
9h 14m1 stop
United Airlines Logo
3:35 pm - 9:29 pm
DSM
-
BDL
4h 54m1 stop
$361United Airlines
Sat, Jan 17 - Tue, Jan 20
United Airlines Logo
9:55 am - 8:34 pm
BDL
-
DSM
11h 39m2 stops
United Airlines Logo
1:35 pm - 11:44 pm
DSM
-
BDL
9h 09m1 stop
$366United Airlines
Sat, Jan 17 - Tue, Jan 20
Southwest Logo
7:25 pm - 11:05 pm
ALB
-
DSM
4h 40m1 stop
Southwest Logo
5:20 am - 5:10 pm
DSM
-
ALB
10h 50m2 stops
$478Southwest
Fri, May 8 - Sun, May 10
Southwest Logo
8:00 am - 11:45 am
ALB
-
DSM
4h 45m1 stop
Southwest Logo
5:20 am - 5:10 pm
DSM
-
ALB
10h 50m2 stops
$482Southwest
Thu, Apr 23 - Sun, Apr 26

Allegiant Air flights from Massachusetts to Des Moines

Our best Allegiant Air deals on Massachusetts to Des Moines flight tickets
Allegiant Air
Jan 2
BOS12:45 pmBoston Logan Intl
3h 13m
DSM2:58 pmDes Moines
Jan 5
DSM8:00 amDes Moines
2h 55m
BOS11:55 amBoston Logan Intl
$126
Find similar
Allegiant Air
Dec 26
BOS12:45 pmBoston Logan Intl
3h 13m
DSM2:58 pmDes Moines
Jan 2
DSM8:00 amDes Moines
2h 55m
BOS11:55 amBoston Logan Intl
$334
Find similar
Allegiant Air
Dec 29
BOS12:45 pmBoston Logan Intl
3h 13m
DSM2:58 pmDes Moines
Jan 2
DSM8:00 amDes Moines
2h 55m
BOS11:55 amBoston Logan Intl
$360
Find similar

Delta flights from Massachusetts to Des Moines

Our best Delta deals on Massachusetts to Des Moines flight tickets
Delta
Jan 14
BDL5:40 amHartford Bradley Intl
6h 44m
1 stop
DSM11:24 amDes Moines
Jan 17
DSM6:24 amDes Moines
4h 38m
1 stop
BDL12:02 pmHartford Bradley Intl
$308
Find similar
Delta
Jan 18
BDL6:04 amHartford Bradley Intl
5h 15m
1 stop
DSM10:19 amDes Moines
Jan 19
DSM5:49 pmDes Moines
4h 51m
1 stop
BDL11:40 pmHartford Bradley Intl
$320
Find similar
Delta
Jan 11
ALB5:30 amAlbany Intl
6h 54m
1 stop
DSM11:24 amDes Moines
Jan 18
DSM6:24 amDes Moines
4h 25m
1 stop
ALB11:49 amAlbany Intl
$354
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Massachusetts to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 22, 2025.
Use the filters below to find and compare flights from Massachusetts to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Fri 1/2

12:45 pm-2:58 pm

Nonstop3h 13m

Des Moines

Mon 1/5

8:00 am-11:55 am

Nonstop2h 55m

$126

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Mon 1/5

12:45 pm-2:58 pm

Nonstop3h 13m

Des Moines

Sun 1/11

2:58 pm-1:19 am

2 stops33h 21m

$194

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Mon 1/5

12:45 pm-2:58 pm

Nonstop3h 13m

Des Moines

Sun 1/11

4:30 pm-5:44 pm

3 stops48h 14m

$205

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Mon 1/5

12:45 pm-2:58 pm

Nonstop3h 13m

Des Moines

Thu 1/8

2:58 pm-12:49 pm

1 stop20h 51m

$230

HartfordDes Moines

BDL - DSM

BDLDSM

Hartford Bradley Intl

Wed 1/14

5:40 am-11:24 am

1 stop6h 44m

Des Moines

Sat 1/17

6:24 am-12:02 pm

1 stop4h 38m

$308

HartfordDes Moines

BDL - DSM

BDLDSM

Hartford Bradley Intl

Sun 1/18

6:04 am-10:19 am

1 stop5h 15m

Des Moines

Mon 1/19

5:49 pm-11:40 pm

1 stop4h 51m

$320

HartfordDes Moines

BDL - DSM

BDLDSM

Hartford Bradley Intl

Sat 1/17

3:30 pm-11:44 pm

1 stop9h 14m

Des Moines

Tue 1/20

3:35 pm-9:29 pm

1 stop4h 54m

$361

HartfordDes Moines

BDL - DSM

BDLDSM

Hartford Bradley Intl

Sat 1/17

9:55 am-8:34 pm

2 stops11h 39m

Des Moines

Tue 1/20

1:35 pm-11:44 pm

1 stop9h 09m

$366

AlbanyDes Moines

ALB - DSM

ALBDSM

Albany Intl

Fri 5/8

7:25 pm-11:05 pm

1 stop4h 40m

Des Moines

Sun 5/10

5:20 am-5:10 pm

2 stops10h 50m

$478

AlbanyDes Moines

ALB - DSM

ALBDSM

Albany Intl

Thu 4/23

8:00 am-11:45 am

1 stop4h 45m

Des Moines

Sun 4/26

5:20 am-5:10 pm

2 stops10h 50m

$482

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Des Moines from

How to get the cheapest flight ticket from Massachusetts to Des Moines

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Des Moines?

If you’re not able to fly to Des Moines in December, then September is your next best option. Flight prices from Massachusetts to Des Moines during September average around $306.

What is the cheapest day to depart on your flight to Des Moines?

The cheapest day to depart from Massachusetts to Des Moines is on a Thursday. Travelers who choose to depart for Des Moines on a Thursday will often find tickets for as low as $125. Flights from Massachusetts to Des Moines on a Wednesday will generally be more expensive and average around $309. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Des Moines?

According to our data, the cheapest time of day to fly to Des Moines is in the morning. momondo users have found flights departing from Massachusetts to Des Moines in the morning for as low as $161. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Try not to purchase tickets in the afternoon because they tend to be around $466. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Massachusetts to Des Moines flight route?

Fly from Boston Logan Intl to Des Moines for the best Massachusetts - Des Moines flight prices

How far in advance should I book a flight to Des Moines?

You are more likely to see cheaper flights to Des Moines from Massachusetts when booking weeks ahead of your departure date. In general, you can expect to find flights to Des Moines for around $354 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Des Moines from Massachusetts for as low as $166 on momondo.

What cabin class options are available on Massachusetts to Des Moines flights?

There is only 1 cabin class available to choose from on Massachusetts to Des Moines flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Massachusetts to Des Moines flights?

No. A direct flight is the cheapest option for a flight between Massachusetts to Des Moines.

Cheap Massachusetts to Des Moines flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Massachusetts to Des Moines

Best Price Found

$55

Fastest flight time

3h 07m

Direct flights

Tue and Sat

Airports in Des Moines

1 airport
The best one-way flight to Des Moines from Massachusetts in the past 72 hours is $55. The best round-trip flight deal from Massachusetts to Des Moines found on momondo in the last 72 hours is $112.
The fastest flight from Massachusetts to Des Moines takes 3h 07m
Direct flights go from Massachusetts to Des Moines on Tuesday and Saturday. The only airline offering direct flights is Allegiant Air.
There is 1 airport in Des Moines. From Massachusetts there are direct flights to Des Moines (DSM).
Search flight deals

  • When did momondo last update prices for flights from Massachusetts to Des Moines Airport?

    Prices for flights from Massachusetts to Des Moines Airport refresh daily.

  • How many operators does momondo search for flights from Massachusetts to Des Moines Airport?

  • How old do you have to be to fly from Massachusetts to Des Moines Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Massachusetts to Des Moines Airport.

  • What documentation or ID do you need to fly to Des Moines Airport?

    The travel and health documents required for your trip to Des Moines Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Des Moines Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Massachusetts to Des Moines?

Best airlines flying from Massachusetts to Des Moines

Compare and see reviews for airlines that fly from Massachusetts to Des Moines with momondo
Airline
Rating
Free Cancellation
Price
Allegiant AirPriceFrom $93Free CancellationRating
7.2
701 reviews
Search Allegiant Air flights
DeltaPriceFrom $260Free CancellationRating
7.9
8,014 reviews
Search Delta flights
United AirlinesPriceFrom $289Free CancellationRating
7.4
9,102 reviews
Search United Airlines flights
American AirlinesPriceFrom $296Free CancellationRating
7.2
11,053 reviews
Search American Airlines flights
SouthwestPriceFrom $333Free CancellationRating
8.0
4,252 reviews
Search Southwest flights

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
West Des Moines
Ames
Ankeny
Altoona
Urbandale
Clive
Pella
Newton
Johnston
Osceola
Boone
Norwalk
Grinnell
Oskaloosa
Carlisle

Why use momondo?

Why should I use momondo to find a flight deal from Massachusetts to Des Moines?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Massachusetts to Des Moines. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Massachusetts to Des Moines with flexible booking policies on momondo?

Yes. All flights to Des Moines from Massachusetts on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Massachusetts to Des Moines?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Des Moines from Massachusetts.

I’m not ready to book a flight from Massachusetts to Des Moines right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Des Moines, momondo offers a useful price alert feature which will track prices for flights to Des Moines from Massachusetts and alert you when they change.

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