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Cheap flights from Madrid to Panama City from $522

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madrid to Panama City departing on 9/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Madrid to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
5:55 am - 9:44 am
MAD
-
ECP
34h 49m
2 stops
United Airlines Logo
2:28 pm - 8:05 am
ECP
-
MAD
34h 37m
2 stops
$809United Airlines
Tue, Jun 2 - Tue, Aug 25
United Airlines Logo
5:55 am - 9:44 am
MAD
-
ECP
34h 49m
2 stops
United Airlines Logo
2:05 pm - 8:50 am
ECP
-
MAD
35h 45m
2 stops
$816United Airlines
Wed, May 27 - Wed, Jun 10
United Airlines Logo
1:30 pm - 8:01 pm
MAD
-
ECP
37h 31m
2 stops
United Airlines Logo
2:28 pm - 4:00 pm
ECP
-
MAD
18h 32m
2 stops
$818United Airlines
Tue, Jun 2 - Mon, Aug 31
United Airlines Logo
1:30 pm - 8:01 pm
MAD
-
ECP
37h 31m
2 stops
United Airlines Logo
2:28 pm - 7:30 pm
ECP
-
MAD
22h 02m
2 stops
$826United Airlines
Tue, Jun 2 - Mon, Aug 31
KLM Logo
9:50 am - 6:36 pm
MAD
-
ECP
15h 46m
1 stop
KLM Logo
9:23 am - 6:20 am
ECP
-
MAD
13h 57m
2 stops
$833KLM
Tue, Jun 2 - Mon, Aug 31
United Airlines Logo
5:55 am - 8:01 pm
MAD
-
ECP
21h 06m
2 stops
United Airlines Logo
6:30 am - 6:50 am
ECP
-
MAD
17h 20m
2 stops
$834United Airlines
Tue, May 26 - Mon, Jun 8
Delta Logo
6:00 am - 7:09 pm
MAD
-
ECP
20h 09m
2 stops
Delta Logo
7:05 pm - 4:45 pm
ECP
-
MAD
14h 40m
2 stops
$836Delta
Mon, May 25 - Mon, Jun 8
KLM Logo
9:50 am - 6:36 pm
MAD
-
ECP
15h 46m
1 stop
KLM Logo
9:23 am - 6:20 am
ECP
-
MAD
13h 57m
2 stops
$840KLM
Tue, Jun 2 - Mon, Aug 31
Delta Logo
9:50 am - 8:30 am
MAD
-
ECP
29h 40m
1 stop
Delta Logo
7:05 pm - 4:45 pm
ECP
-
MAD
14h 40m
2 stops
$841Delta
Thu, May 28 - Mon, Jun 8
United Airlines Logo
11:15 am - 1:21 pm
MAD
-
ECP
33h 06m
2 stops
United Airlines Logo
6:30 am - 6:50 am
ECP
-
MAD
17h 20m
2 stops
$848United Airlines
Sun, May 24 - Mon, Jun 8

Delta flights from Madrid to Panama City, Florida

Our best Delta deals on Madrid to Panama City, Florida flight tickets
Delta
May 25
MAD6:00 amMadrid Barajas
20h 09m
2 stops
ECP7:09 pmPanama City NW Florida Beaches
Jun 8
ECP7:05 pmPanama City NW Florida Beaches
14h 40m
2 stops
MAD4:45 pmMadrid Barajas
$836
Delta
May 28
MAD9:50 amMadrid Barajas
29h 40m
1 stop
ECP8:30 amPanama City NW Florida Beaches
Jun 8
ECP7:05 pmPanama City NW Florida Beaches
14h 40m
2 stops
MAD4:45 pmMadrid Barajas
$841
Delta
Jun 2
MAD9:50 amMadrid Barajas
20h 11m
1 stop
ECP11:01 pmPanama City NW Florida Beaches
Aug 31
ECP7:45 amPanama City NW Florida Beaches
21h 30m
1 stop
MAD12:15 pmMadrid Barajas
$900

American Airlines flights from Madrid to Panama City, Florida

Our best American Airlines deals on Madrid to Panama City, Florida flight tickets
American Airlines
May 27
MAD1:00 pmMadrid Barajas
17h 40m
1 stop
ECP11:40 pmPanama City NW Florida Beaches
Jun 10
ECP1:15 pmPanama City NW Florida Beaches
13h 20m
1 stop
MAD9:35 amMadrid Barajas
$977
American Airlines
May 27
MAD1:00 pmMadrid Barajas
17h 40m
1 stop
ECP11:40 pmPanama City NW Florida Beaches
Jun 8
ECP3:22 pmPanama City NW Florida Beaches
17h 28m
2 stops
MAD3:50 pmMadrid Barajas
$989
American Airlines
May 26
MAD10:25 amMadrid Barajas
31h 03m
2 stops
ECP10:28 amPanama City NW Florida Beaches
Jun 8
ECP3:22 pmPanama City NW Florida Beaches
16h 03m
1 stop
MAD2:25 pmMadrid Barajas
$1,000

momondo Fare Finder

 
Customize your flight search to find flights from Madrid to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Madrid to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/2

5:55 am-9:44 am

2 stops34h 49m

Panama City NW Florida Beaches

Tue 8/25

2:28 pm-8:05 am

2 stops34h 37m

$809

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 5/27

5:55 am-9:44 am

2 stops34h 49m

Panama City NW Florida Beaches

Wed 6/10

2:05 pm-8:50 am

2 stops35h 45m

$816

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/2

1:30 pm-8:01 pm

2 stops37h 31m

Panama City NW Florida Beaches

Mon 8/31

2:28 pm-4:00 pm

2 stops18h 32m

$818

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/2

1:30 pm-8:01 pm

2 stops37h 31m

Panama City NW Florida Beaches

Mon 8/31

2:28 pm-7:30 pm

2 stops22h 02m

$826
Quickest round-trip

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/2

9:50 am-6:36 pm

1 stop15h 46m

Panama City NW Florida Beaches

Mon 8/31

9:23 am-6:20 am

2 stops13h 57m

$833

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 5/26

5:55 am-8:01 pm

2 stops21h 06m

Panama City NW Florida Beaches

Mon 6/8

6:30 am-6:50 am

2 stops17h 20m

$834

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 5/25

6:00 am-7:09 pm

2 stops20h 09m

Panama City NW Florida Beaches

Mon 6/8

7:05 pm-4:45 pm

2 stops14h 40m

$836

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/2

9:50 am-6:36 pm

1 stop15h 46m

Panama City NW Florida Beaches

Mon 8/31

9:23 am-6:20 am

2 stops13h 57m

$840

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Thu 5/28

9:50 am-8:30 am

1 stop29h 40m

Panama City NW Florida Beaches

Mon 6/8

7:05 pm-4:45 pm

2 stops14h 40m

$841

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sun 5/24

11:15 am-1:21 pm

2 stops33h 06m

Panama City NW Florida Beaches

Mon 6/8

6:30 am-6:50 am

2 stops17h 20m

$848

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Madrid to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Madrid to Panama City, Florida flights?

You could potentially save up to 14% on your flight if you consider stops on a Madrid to Panama City, Florida flight.

When to book flights from Madrid to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Madrid to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Madrid to Panama City, Florida (MAD to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madrid to Panama City, Florida

Fastest flight time

34h 49m

Direct flights

None
The fastest flight from Madrid to Panama City, Florida takes 34h 49m
There are no direct flights from Madrid to Panama City, Florida. There are no popular flight routes from Madrid to Panama City, Florida.
Search flight deals

  • How far is Madrid Barajas to Panama City NW Florida Beaches by plane?

    The distance between Madrid Barajas and Panama City NW Florida Beaches is about 4508.8 mi. Flights usually cover this in 34h 49m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Madrid Barajas Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Madrid Barajas Airport to Panama City NW Florida Beaches Airport refresh daily.

  • How old do you have to be to fly from Madrid Barajas Airport to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Madrid Barajas Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Madrid to Panama City?

Finding the right flight to Panama City from Madrid is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Madrid to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Madrid with this policy.

How can momondo help me find flights from Madrid to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Madrid. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Madrid to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Madrid and alert you when they change.

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