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Cheap flights from Madrid to Panama City from $757

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madrid to Panama City departing on 2/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Madrid to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
10:25 am - 11:12 pm
MAD
-
ECP
19h 47m
2 stops
Delta Logo
6:00 am - 6:20 am
ECP
-
MAD
17h 20m
2 stops
$811Delta
Fri, May 1 - Sun, May 10
Delta Logo
12:45 pm - 8:35 am
MAD
-
ECP
26h 50m
1 stop
Delta Logo
6:00 am - 6:20 am
ECP
-
MAD
17h 20m
2 stops
$817Delta
Thu, Apr 30 - Sun, May 10
Virgin Atlantic Logo
12:45 pm - 11:12 pm
MAD
-
ECP
17h 27m
1 stop
Virgin Atlantic Logo
2:47 pm - 12:15 pm
ECP
-
MAD
14h 28m
1 stop
$937Virgin Atlantic
Thu, Apr 30 - Sun, May 10
Air France Logo
9:50 am - 3:16 pm
MAD
-
ECP
12h 26m
1 stop
Air France Logo
1:30 pm - 11:20 am
ECP
-
MAD
14h 50m
2 stops
$971Air France
Mon, Jun 29 - Wed, Jul 15
Virgin Atlantic Logo
9:50 am - 3:16 pm
MAD
-
ECP
12h 26m
1 stop
Virgin Atlantic Logo
2:47 pm - 12:15 pm
ECP
-
MAD
14h 28m
1 stop
$975Virgin Atlantic
Mon, Jun 29 - Wed, Jul 15
United Airlines Logo
11:15 am - 1:09 pm
MAD
-
ECP
32h 54m
2 stops
United Airlines Logo
6:40 am - 6:50 am
ECP
-
MAD
17h 10m
2 stops
$979United Airlines
Thu, Jul 2 - Mon, Jul 13
United Airlines Logo
12:45 pm - 4:17 pm
MAD
-
ECP
34h 32m
2 stops
United Airlines Logo
4:55 pm - 6:50 am
ECP
-
MAD
30h 55m
2 stops
$982United Airlines
Sat, Jun 27 - Thu, Jul 16
Delta Logo
12:45 pm - 8:17 am
MAD
-
ECP
26h 32m
2 stops
Delta Logo
1:30 pm - 3:35 pm
ECP
-
MAD
19h 05m
2 stops
$995Delta
Mon, Jun 29 - Wed, Jul 15
Delta Logo
9:50 am - 3:16 pm
MAD
-
ECP
12h 26m
1 stop
Delta Logo
6:00 am - 6:20 am
ECP
-
MAD
17h 20m
2 stops
$999Delta
Mon, Jun 29 - Sat, Jul 18
United Airlines Logo
10:50 am - 1:09 pm
MAD
-
ECP
33h 19m
2 stops
United Airlines Logo
6:40 am - 6:50 am
ECP
-
MAD
17h 10m
2 stops
$1,003United Airlines
Wed, Jul 1 - Wed, Jul 15

Delta flights from Madrid to Panama City, Florida

Our best Delta deals on Madrid to Panama City, Florida flight tickets
Delta
May 1
MAD1:05 pmMadrid Barajas
17h 07m
2 stops
ECP11:12 pmPanama City NW Florida Beaches
May 12
ECP9:23 amPanama City NW Florida Beaches
19h 52m
1 stop
MAD12:15 pmMadrid Barajas
$811
Delta
Apr 30
MAD2:35 pmMadrid Barajas
26h 40m
2 stops
ECP10:15 amPanama City NW Florida Beaches
May 9
ECP6:00 amPanama City NW Florida Beaches
17h 20m
2 stops
MAD6:20 amMadrid Barajas
$817
Delta
Jun 29
MAD12:45 pmMadrid Barajas
26h 32m
2 stops
ECP8:17 amPanama City NW Florida Beaches
Jul 15
ECP1:30 pmPanama City NW Florida Beaches
19h 05m
2 stops
MAD3:35 pmMadrid Barajas
$995

Virgin Atlantic flights from Madrid to Panama City, Florida

Our best Virgin Atlantic deals on Madrid to Panama City, Florida flight tickets
Virgin Atlantic
Apr 30
MAD12:45 pmMadrid Barajas
17h 27m
1 stop
ECP11:12 pmPanama City NW Florida Beaches
May 10
ECP2:47 pmPanama City NW Florida Beaches
14h 28m
1 stop
MAD12:15 pmMadrid Barajas
$937
Virgin Atlantic
Jun 29
MAD9:50 amMadrid Barajas
12h 26m
1 stop
ECP3:16 pmPanama City NW Florida Beaches
Jul 15
ECP2:47 pmPanama City NW Florida Beaches
14h 28m
1 stop
MAD12:15 pmMadrid Barajas
$975

momondo Fare Finder

 
Customize your flight search to find flights from Madrid to Panama City, Florida that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Madrid to Panama City, Florida that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 5/1

10:25 am-11:12 pm

2 stops19h 47m

Panama City NW Florida Beaches

Sun 5/10

6:00 am-6:20 am

2 stops17h 20m

$811

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Thu 4/30

12:45 pm-8:35 am

1 stop26h 50m

Panama City NW Florida Beaches

Sun 5/10

6:00 am-6:20 am

2 stops17h 20m

$817

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Thu 4/30

12:45 pm-11:12 pm

1 stop17h 27m

Panama City NW Florida Beaches

Sun 5/10

2:47 pm-12:15 pm

1 stop14h 28m

$937

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 6/29

9:50 am-3:16 pm

1 stop12h 26m

Panama City NW Florida Beaches

Wed 7/15

1:30 pm-11:20 am

2 stops14h 50m

$971

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 6/29

9:50 am-3:16 pm

1 stop12h 26m

Panama City NW Florida Beaches

Wed 7/15

2:47 pm-12:15 pm

1 stop14h 28m

$975

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Thu 7/2

11:15 am-1:09 pm

2 stops32h 54m

Panama City NW Florida Beaches

Mon 7/13

6:40 am-6:50 am

2 stops17h 10m

$979

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sat 6/27

12:45 pm-4:17 pm

2 stops34h 32m

Panama City NW Florida Beaches

Thu 7/16

4:55 pm-6:50 am

2 stops30h 55m

$982

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 6/29

12:45 pm-8:17 am

2 stops26h 32m

Panama City NW Florida Beaches

Wed 7/15

1:30 pm-3:35 pm

2 stops19h 05m

$995

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 6/29

9:50 am-3:16 pm

1 stop12h 26m

Panama City NW Florida Beaches

Sat 7/18

6:00 am-6:20 am

2 stops17h 20m

$999

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 7/1

10:50 am-1:09 pm

2 stops33h 19m

Panama City NW Florida Beaches

Wed 7/15

6:40 am-6:50 am

2 stops17h 10m

$1,003

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Madrid to Panama City, Florida

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Madrid Barajas to Panama City NW Florida Beaches?

American Airlines is the most popular carrier operating from Madrid Barajas to Panama City NW Florida Beaches

When to book flights from Madrid to Panama City, Florida

Are you open to changing your travel dates? Check out the ideal times to fly from Madrid to Panama City, Florida according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Madrid to Panama City, Florida (MAD to ECP) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madrid to Panama City, Florida

Fastest flight time

26h 50m

Direct flights

None
The fastest flight from Madrid to Panama City, Florida takes 26h 50m
There are no direct flights from Madrid to Panama City, Florida. There are no popular flight routes from Madrid to Panama City, Florida.
Search flight deals

  • How far is Madrid Barajas to Panama City NW Florida Beaches by plane?

    The distance between Madrid Barajas and Panama City NW Florida Beaches is about 4508.8 mi. Flights usually cover this in 26h 50m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Madrid Barajas Airport to Panama City NW Florida Beaches Airport?

    Prices for flights from Madrid Barajas Airport to Panama City NW Florida Beaches Airport refresh daily.

  • How old do you have to be to fly from Madrid Barajas Airport to Panama City NW Florida Beaches Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Madrid Barajas Airport to Panama City NW Florida Beaches Airport.

  • What documentation or ID do you need to fly to Panama City NW Florida Beaches Airport?

    The travel and health documents you'll need for your trip to Panama City NW Florida Beaches Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City NW Florida Beaches Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Panama City Beach
Rosemary Beach
Port St. Joe
Seaside
Mexico Beach
Seagrove Beach
Freeport

Why use momondo?

Why should I use momondo to find a flight deal from Madrid to Panama City?

Finding the right flight to Panama City from Madrid is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama City quick and easy, saving you time and money.

Can I find flights from Madrid to Panama City with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama City from Madrid with this policy.

How can momondo help me find flights from Madrid to Panama City?

momondo provides multiple filters to help you find the best flight to Panama City from Madrid. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Madrid to Panama City right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama City, momondo offers a useful price alert feature which will track prices for flights to Panama City from Madrid and alert you when they change.

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