Cheap flights from New York LaGuardia Airport to Missouri from $147

In general, February is the cheapest month to fly from New York LaGuardia Airport to Missouri. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $373. If you aren’t able to travel to Missouri during the month of February, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $384.

The cheapest day to depart from New York LaGuardia Airport to Missouri is on a Thursday when prices can be found for as low as $385. Flights from New York LaGuardia Airport to Missouri on a Sunday will generally be more expensive and average around $497. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Missouri is in the morning. momondo users have found flights departing from New York LaGuardia Airport to Missouri in the morning for as low as $401. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. Flights to Missouri are more costly in the afternoon, with an average ticket price of $419. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

Fly from New York LaGuardia to Lambert-St Louis for the best New York LaGuardia - Missouri flight prices

You are more likely to see cheaper flights to Missouri from New York LaGuardia Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Missouri for around $418 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Missouri from New York LaGuardia Airport for as low as $260 on momondo.

There are 4 cabin classes available to choose from on New York LaGuardia Airport to Missouri flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Delta, Southwest, and United Airlines are the most popular carriers operating from New York LaGuardia to Missouri

Delta, Southwest and American Airlines are the top three most popular airlines that fly to Missouri from New York LaGuardia Airport according to our data. Delta is the first choice among our users, with 48% of people opting to fly with this airline when traveling to Missouri. Keep in mind that there are 3 different airlines that fly to Missouri on a routine basis, so you have a few additional options to choose from.

The number of flights available between New York LaGuardia Airport and Missouri is 8 per day as of October 2026. The most frequent departure time is 3:00PM, with 39% of daily flights leaving in the afternoon.

59 flights are operational weekly from New York LaGuardia Airport to Missouri as of October 2026. The most popular departure day for this route is Fri, with 39% of flights per week taking off on this day.