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Cheap flights from La Crosse to Louisville from $263

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from La Crosse to Louisville departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from La Crosse to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
5:34 pm - 10:19 pm
LSE
-
SDF
3h 45m
1 stop
American Airlines Logo
7:46 pm - 12:06 am
SDF
-
LSE
5h 20m
1 stop
$298American Airlines
Thu, May 28 - Sat, May 30
American Airlines Logo
5:34 pm - 10:19 pm
LSE
-
SDF
3h 45m
1 stop
American Airlines Logo
5:43 pm - 12:06 am
SDF
-
LSE
7h 23m
2 stops
$304American Airlines
Thu, May 28 - Sat, May 30
American Airlines Logo
11:52 am - 12:28 am
LSE
-
SDF
11h 36m
2 stops
American Airlines Logo
1:21 pm - 12:06 am
SDF
-
LSE
11h 45m
2 stops
$309American Airlines
Thu, May 28 - Sat, May 30
American Airlines Logo
5:40 am - 10:46 am
LSE
-
SDF
4h 06m
1 stop
American Airlines Logo
6:00 am - 9:35 am
SDF
-
LSE
4h 35m
1 stop
$524American Airlines
Thu, Apr 9 - Sun, Apr 12
United Airlines Logo
8:15 am - 6:56 pm
LSE
-
SDF
9h 41m
1 stop
United Airlines Logo
5:35 am - 6:10 pm
SDF
-
LSE
13h 35m
1 stop
$667United Airlines
Sat, Aug 29 - Wed, Sep 2
United Airlines Logo
8:15 am - 4:51 pm
LSE
-
SDF
7h 36m
1 stop
United Airlines Logo
10:05 am - 11:07 pm
SDF
-
LSE
14h 02m
2 stops
$685United Airlines
Sat, Aug 29 - Wed, Sep 2
American Airlines Logo
5:40 am - 3:54 pm
LSE
-
SDF
9h 14m
2 stops
American Airlines Logo
6:00 am - 9:35 am
SDF
-
LSE
4h 35m
1 stop
$704American Airlines
Thu, Apr 9 - Sun, Apr 12
American Airlines Logo
5:40 am - 3:54 pm
LSE
-
SDF
9h 14m
2 stops
American Airlines Logo
1:18 pm - 11:54 pm
SDF
-
LSE
11h 36m
2 stops
$1,229American Airlines
Thu, Apr 9 - Sun, Apr 12

American Airlines flights from La Crosse to Louisville

Our best American Airlines deals on La Crosse to Louisville flight tickets
American Airlines
May 28
LSE5:34 pmLa Crosse
3h 45m
1 stop
SDF10:19 pmLouisville Intl
May 30
SDF7:46 pmLouisville Intl
5h 20m
1 stop
LSE12:06 amLa Crosse
$298
American Airlines
May 28
LSE5:34 pmLa Crosse
3h 45m
1 stop
SDF10:19 pmLouisville Intl
May 30
SDF5:43 pmLouisville Intl
7h 23m
2 stops
LSE12:06 amLa Crosse
$304
American Airlines
May 28
LSE11:52 amLa Crosse
11h 36m
2 stops
SDF12:28 amLouisville Intl
May 30
SDF1:21 pmLouisville Intl
11h 45m
2 stops
LSE12:06 amLa Crosse
$309

United Airlines flights from La Crosse to Louisville

Our best United Airlines deals on La Crosse to Louisville flight tickets
United Airlines
Aug 29
LSE8:15 amLa Crosse
9h 41m
1 stop
SDF6:56 pmLouisville Intl
Sep 2
SDF5:35 amLouisville Intl
13h 35m
1 stop
LSE6:10 pmLa Crosse
$667
United Airlines
Aug 29
LSE8:15 amLa Crosse
7h 36m
1 stop
SDF4:51 pmLouisville Intl
Sep 2
SDF10:05 amLouisville Intl
14h 02m
2 stops
LSE11:07 pmLa Crosse
$685

momondo Fare Finder

 
Customize your flight search to find flights from La Crosse to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from La Crosse to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

La CrosseLouisville

LSE - SDF

LSESDF

La Crosse

Thu 5/28

5:34 pm-10:19 pm

1 stop3h 45m

Louisville Intl

Sat 5/30

7:46 pm-12:06 am

1 stop5h 20m

$298

La CrosseLouisville

LSE - SDF

LSESDF

La Crosse

Thu 5/28

5:34 pm-10:19 pm

1 stop3h 45m

Louisville Intl

Sat 5/30

5:43 pm-12:06 am

2 stops7h 23m

$304

La CrosseLouisville

LSE - SDF

LSESDF

La Crosse

Thu 5/28

11:52 am-12:28 am

2 stops11h 36m

Louisville Intl

Sat 5/30

1:21 pm-12:06 am

2 stops11h 45m

$309
Quickest round-trip

La CrosseLouisville

LSE - SDF

LSESDF

La Crosse

Thu 4/9

5:40 am-10:46 am

1 stop4h 06m

Louisville Intl

Sun 4/12

6:00 am-9:35 am

1 stop4h 35m

$524

La CrosseLouisville

LSE - SDF

LSESDF

La Crosse

Sat 8/29

8:15 am-6:56 pm

1 stop9h 41m

Louisville Intl

Wed 9/2

5:35 am-6:10 pm

1 stop13h 35m

$667

La CrosseLouisville

LSE - SDF

LSESDF

La Crosse

Sat 8/29

8:15 am-4:51 pm

1 stop7h 36m

Louisville Intl

Wed 9/2

10:05 am-11:07 pm

2 stops14h 02m

$685

La CrosseLouisville

LSE - SDF

LSESDF

La Crosse

Thu 4/9

5:40 am-3:54 pm

2 stops9h 14m

Louisville Intl

Sun 4/12

6:00 am-9:35 am

1 stop4h 35m

$704

La CrosseLouisville

LSE - SDF

LSESDF

La Crosse

Thu 4/9

5:40 am-3:54 pm

2 stops9h 14m

Louisville Intl

Sun 4/12

1:18 pm-11:54 pm

2 stops11h 36m

$1,229
Cheapest one-way
Quickest one-way

La CrosseLouisville

LSE - SDF

LSESDF

La Crosse

Mon 4/27

5:40 am-10:46 am

1 stop4h 06m

$263

La CrosseLouisville

LSE - SDF

LSESDF

La Crosse

Mon 4/27

10:05 am-10:08 pm

2 stops11h 03m

$335

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Louisville from

How to get the cheapest flight ticket from La Crosse to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from La Crosse to Louisville Intl?

American Airlines is the most popular carrier operating from La Crosse to Louisville Intl

When to book flights from La Crosse to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from La Crosse to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap La Crosse to Louisville (LSE to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from La Crosse to Louisville

Fastest flight time

4h 06m

Direct flights

None
The fastest flight from La Crosse to Louisville takes 4h 06m
There are no direct flights from La Crosse to Louisville. There are no popular flight routes from La Crosse to Louisville.
Search flight deals

  • How far is La Crosse to Louisville Intl by plane?

    La Crosse and Louisville Intl are 477.9 mi apart from one another. In terms of flight time, this usually takes a little over 4h 06m.

  • When did momondo last update prices for flights from La Crosse Airport to Louisville Intl Airport?

    Prices for flights from La Crosse Airport to Louisville Intl Airport refresh daily.

  • How old do you have to be to fly from La Crosse Airport to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from La Crosse Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The travel and health documents you'll need for your trip to Louisville Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Louisville Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
Bardstown
West Baden Springs
Jeffersonville
New Albany
Shepherdsville
Corydon
Brandenburg
Elizabeth
Charlestown
Springfield
Georgetown

Why use momondo?

Why should I use momondo to find a flight deal from La Crosse to Louisville?

Finding the right flight to Louisville from La Crosse is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Louisville quick and easy, saving you time and money.

Can I find flights from La Crosse to Louisville with flexible booking policies on momondo?

All flight searches from La Crosse to Louisville on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from La Crosse to Louisville?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from La Crosse to Louisville.

I’m not ready to book a flight from La Crosse to Louisville right now. Can momondo alert me if prices change?

Yes. momondo can track prices for La Crosse to Louisville flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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