Cheap flights from Knoxville to South Africa from $650

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to South Africa departing on 4/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

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Qatar Airways Logo
10:56 am - 4:10 pm
TYS
-
JNB
47h 14m
2 stops
Qatar Airways Logo
8:40 pm - 8:18 pm
JNB
-
TYS
29h 38m
2 stops
$1,500Qatar Airways
Wed, Apr 29 - Wed, May 6
Qatar Airways Logo
10:56 am - 10:15 am
TYS
-
CPT
41h 19m
2 stops
Qatar Airways Logo
1:00 pm - 11:56 pm
CPT
-
TYS
40h 56m
2 stops
$1,561Qatar Airways
Thu, Apr 9 - Thu, Apr 16
Ethiopian Air Logo
2:25 pm - 3:55 am
TYS
-
JNB
31h 30m
3 stops
Ethiopian Air Logo
2:30 pm - 2:34 pm
JNB
-
TYS
30h 04m
3 stops
$1,743Ethiopian Air
Wed, Apr 29 - Wed, May 6
Qatar Airways Logo
1:20 pm - 11:30 am
TYS
-
CPT
40h 10m
2 stops
Qatar Airways Logo
1:00 pm - 3:19 pm
CPT
-
TYS
32h 19m
2 stops
$1,770Qatar Airways
Thu, Apr 30 - Thu, May 7
Qatar Airways Logo
11:43 am - 11:30 am
TYS
-
CPT
41h 47m
2 stops
Qatar Airways Logo
1:00 pm - 11:59 pm
CPT
-
TYS
40h 59m
2 stops
$1,827Qatar Airways
Sun, May 24 - Mon, Jun 8
Ethiopian Air Logo
6:30 am - 2:35 pm
TYS
-
CPT
26h 05m
2 stops
Ethiopian Air Logo
1:50 pm - 2:27 pm
CPT
-
TYS
30h 37m
3 stops
$1,948Ethiopian Air
Sun, May 24 - Mon, Jun 8
Delta Logo
12:03 pm - 7:40 pm
TYS
-
JNB
25h 37m
1 stop
Delta Logo
11:15 pm - 8:28 pm
JNB
-
TYS
27h 13m
2 stops
$2,285Delta
Wed, Apr 29 - Wed, May 6
Virgin Atlantic Logo
3:01 pm - 7:40 pm
TYS
-
JNB
22h 39m
1 stop
Virgin Atlantic Logo
9:55 pm - 5:14 pm
JNB
-
TYS
25h 19m
1 stop
$2,545Virgin Atlantic
Wed, Apr 29 - Wed, May 6
British Airways Logo
5:00 pm - 9:25 am
TYS
-
JNB
58h 25m
2 stops
British Airways Logo
9:15 pm - 3:48 pm
JNB
-
TYS
48h 33m
2 stops
$3,638British Airways
Sat, Mar 28 - Sat, Apr 4
British Airways Logo
6:38 pm - 9:25 am
TYS
-
JNB
56h 47m
2 stops
British Airways Logo
9:15 pm - 3:48 pm
JNB
-
TYS
48h 33m
2 stops
$3,642British Airways
Sat, Mar 28 - Sat, Apr 4

British Airways flights from Knoxville to South Africa

Our best British Airways deals on Knoxville to South Africa flight tickets
British Airways
Mar 28
TYS5:00 pmKnoxville McGhee Tyson
58h 25m
2 stops
JNB9:25 amJohannesburg OR Tambo
Apr 4
JNB9:15 pmJohannesburg OR Tambo
48h 33m
2 stops
TYS3:48 pmKnoxville McGhee Tyson
$3,638
British Airways
Mar 28
TYS6:38 pmKnoxville McGhee Tyson
56h 47m
2 stops
JNB9:25 amJohannesburg OR Tambo
Apr 4
JNB9:15 pmJohannesburg OR Tambo
48h 33m
2 stops
TYS3:48 pmKnoxville McGhee Tyson
$3,642
British Airways
Mar 28
TYS11:42 amKnoxville McGhee Tyson
37h 18m
2 stops
JNB7:00 amJohannesburg OR Tambo
Apr 4
JNB9:15 pmJohannesburg OR Tambo
29h 50m
2 stops
TYS9:05 pmKnoxville McGhee Tyson
$4,188

Delta flights from Knoxville to South Africa

Our best Delta deals on Knoxville to South Africa flight tickets
Delta
May 23
TYS7:51 amKnoxville McGhee Tyson
31h 34m
2 stops
CPT9:25 pmCape Town Intl
Jun 7
CPT8:05 pmCape Town Intl
23h 20m
1 stop
TYS1:25 pmKnoxville McGhee Tyson
$2,146
Delta
May 22
TYS5:20 pmKnoxville McGhee Tyson
46h 05m
2 stops
CPT9:25 pmCape Town Intl
Jun 7
CPT8:05 pmCape Town Intl
19h 06m
1 stop
TYS9:11 amKnoxville McGhee Tyson
$2,153
Delta
May 22
TYS5:20 pmKnoxville McGhee Tyson
46h 05m
2 stops
CPT9:25 pmCape Town Intl
Jun 7
CPT8:05 pmCape Town Intl
24h 35m
2 stops
TYS2:40 pmKnoxville McGhee Tyson
$2,157

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Knoxville to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 4/29

10:56 am-4:10 pm

2 stops47h 14m

Johannesburg OR Tambo

Wed 5/6

8:40 pm-8:18 pm

2 stops29h 38m

$1,500

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Thu 4/9

10:56 am-10:15 am

2 stops41h 19m

Cape Town Intl

Thu 4/16

1:00 pm-11:56 pm

2 stops40h 56m

$1,561

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 4/29

2:25 pm-3:55 am

3 stops31h 30m

Johannesburg OR Tambo

Wed 5/6

2:30 pm-2:34 pm

3 stops30h 04m

$1,743

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Thu 4/30

1:20 pm-11:30 am

2 stops40h 10m

Cape Town Intl

Thu 5/7

1:00 pm-3:19 pm

2 stops32h 19m

$1,770

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Sun 5/24

11:43 am-11:30 am

2 stops41h 47m

Cape Town Intl

Mon 6/8

1:00 pm-11:59 pm

2 stops40h 59m

$1,827

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Sun 5/24

6:30 am-2:35 pm

2 stops26h 05m

Cape Town Intl

Mon 6/8

1:50 pm-2:27 pm

3 stops30h 37m

$1,948

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 4/29

12:03 pm-7:40 pm

1 stop25h 37m

Johannesburg OR Tambo

Wed 5/6

11:15 pm-8:28 pm

2 stops27h 13m

$2,285
Quickest round-trip

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Wed 4/29

3:01 pm-7:40 pm

1 stop22h 39m

Johannesburg OR Tambo

Wed 5/6

9:55 pm-5:14 pm

1 stop25h 19m

$2,545

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sat 3/28

5:00 pm-9:25 am

2 stops58h 25m

Johannesburg OR Tambo

Sat 4/4

9:15 pm-3:48 pm

2 stops48h 33m

$3,638

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sat 3/28

6:38 pm-9:25 am

2 stops56h 47m

Johannesburg OR Tambo

Sat 4/4

9:15 pm-3:48 pm

2 stops48h 33m

$3,642

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to South Africa from

How to get the cheapest flight ticket from Knoxville to South Africa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to South Africa?

Qatar Airways, Ethiopian Air, and Delta are the most popular carriers operating from Knoxville McGhee Tyson to South Africa

Cheap Knoxville to South Africa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to South Africa

Fastest flight time

32h 04m

Direct flights

None
The fastest flight from Knoxville to South Africa takes 32h 04m
There are no direct flights from Knoxville to South Africa. There are no popular flight routes from Knoxville to South Africa.
  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to South Africa?

    Prices for flights from Knoxville McGhee Tyson Airport to South Africa are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to South Africa?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to South Africa.

  • What documentation or ID do you need to fly to South Africa?

    The necessary travel and health documents for your South Africa trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to South Africa?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to South Africa. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to South Africa with flexible booking policies on momondo?

momondo does allow users to show only those flights to South Africa from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to South Africa?

Once you have performed a search for Knoxville to South Africa flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to South Africa right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Africa, momondo offers a useful price alert feature which will track prices for flights to South Africa from Knoxville and alert you when they change.

An easier way to manage your South Africa trip

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1 adult
Thu 4/16
Thu 4/23

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