Cheap flights from Knoxville to South Africa from $829

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to South Africa departing on 4/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

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American Airlines Logo
5:06 pm - 7:00 am
TYS
-
JNB
31h 54m
2 stops
American Airlines Logo
9:15 pm - 6:11 pm
JNB
-
TYS
26h 56m
2 stops
$1,241American Airlines
Tue, May 19 - Wed, Jun 10
American Airlines Logo
2:49 pm - 7:35 am
TYS
-
JNB
33h 46m
2 stops
American Airlines Logo
7:35 pm - 8:24 pm
JNB
-
TYS
31h 49m
2 stops
$1,265American Airlines
Fri, Feb 20 - Fri, Feb 27
American Airlines Logo
4:04 pm - 8:05 am
TYS
-
CPT
34h 01m
2 stops
American Airlines Logo
6:50 pm - 3:48 pm
CPT
-
TYS
26h 58m
2 stops
$1,500American Airlines
Tue, Mar 10 - Tue, Mar 31
British Airways Logo
6:33 pm - 9:25 am
TYS
-
JNB
32h 52m
2 stops
British Airways Logo
9:15 pm - 6:11 pm
JNB
-
TYS
26h 56m
2 stops
$1,599British Airways
Sat, Jul 11 - Sun, Jul 19
American Airlines Logo
2:49 pm - 11:00 am
TYS
-
CPT
38h 11m
2 stops
American Airlines Logo
6:50 pm - 6:11 pm
CPT
-
TYS
29h 21m
2 stops
$1,651American Airlines
Fri, May 15 - Thu, May 28
Lufthansa Logo
7:00 am - 6:30 pm
TYS
-
JNB
29h 30m
1 stop
Lufthansa Logo
10:00 pm - 5:01 pm
JNB
-
TYS
25h 01m
2 stops
$1,656Lufthansa
Tue, May 19 - Wed, Jun 10
Delta Logo
3:13 pm - 9:55 pm
TYS
-
CPT
24h 42m
2 stops
Delta Logo
8:05 pm - 9:16 am
CPT
-
TYS
19h 11m
1 stop
$1,692Delta
Tue, Mar 10 - Tue, Mar 31
Ethiopian Air Logo
7:00 am - 3:55 am
TYS
-
JNB
38h 55m
3 stops
Ethiopian Air Logo
2:30 pm - 2:23 pm
JNB
-
TYS
29h 53m
3 stops
$1,716Ethiopian Air
Tue, May 19 - Wed, Jun 10
British Airways Logo
5:06 pm - 11:00 am
TYS
-
CPT
35h 54m
2 stops
British Airways Logo
6:50 pm - 6:11 pm
CPT
-
TYS
29h 21m
2 stops
$1,786British Airways
Tue, May 19 - Sun, May 31
Ethiopian Air Logo
1:52 pm - 2:35 pm
TYS
-
CPT
42h 43m
2 stops
Ethiopian Air Logo
1:50 pm - 5:01 pm
CPT
-
TYS
33h 11m
3 stops
$1,830Ethiopian Air
Tue, May 19 - Sun, May 31

American Airlines flights from Knoxville to South Africa

Our best American Airlines deals on Knoxville to South Africa flight tickets
American Airlines
May 19
TYS5:06 pmKnoxville McGhee Tyson
31h 54m
2 stops
JNB7:00 amJohannesburg OR Tambo
Jun 10
JNB9:15 pmJohannesburg OR Tambo
26h 56m
2 stops
TYS6:11 pmKnoxville McGhee Tyson
$1,241
American Airlines
Feb 20
TYS2:49 pmKnoxville McGhee Tyson
33h 46m
2 stops
JNB7:35 amJohannesburg OR Tambo
Feb 27
JNB7:35 pmJohannesburg OR Tambo
31h 49m
2 stops
TYS8:24 pmKnoxville McGhee Tyson
$1,265
American Airlines
Mar 10
TYS4:04 pmKnoxville McGhee Tyson
34h 01m
2 stops
CPT8:05 amCape Town Intl
Mar 31
CPT6:50 pmCape Town Intl
26h 58m
2 stops
TYS3:48 pmKnoxville McGhee Tyson
$1,500

British Airways flights from Knoxville to South Africa

Our best British Airways deals on Knoxville to South Africa flight tickets
British Airways
Feb 5
TYS5:15 pmKnoxville McGhee Tyson
55h 20m
2 stops
JNB7:35 amJohannesburg OR Tambo
Feb 8
JNB10:00 pmJohannesburg OR Tambo
27h 46m
2 stops
TYS6:46 pmKnoxville McGhee Tyson
$1,486
British Airways
Feb 5
TYS5:14 pmKnoxville McGhee Tyson
55h 21m
2 stops
JNB7:35 amJohannesburg OR Tambo
Feb 8
JNB7:35 pmJohannesburg OR Tambo
30h 11m
2 stops
TYS6:46 pmKnoxville McGhee Tyson
$1,537
British Airways
Feb 5
TYS5:15 pmKnoxville McGhee Tyson
55h 20m
2 stops
JNB7:35 amJohannesburg OR Tambo
Feb 8
JNB10:00 pmJohannesburg OR Tambo
27h 46m
2 stops
TYS6:46 pmKnoxville McGhee Tyson
$1,538

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to South Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Knoxville to South Africa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 5/19

5:06 pm-7:00 am

2 stops31h 54m

Johannesburg OR Tambo

Wed 6/10

9:15 pm-6:11 pm

2 stops26h 56m

$1,241

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Fri 2/20

2:49 pm-7:35 am

2 stops33h 46m

Johannesburg OR Tambo

Fri 2/27

7:35 pm-8:24 pm

2 stops31h 49m

$1,265

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Tue 3/10

4:04 pm-8:05 am

2 stops34h 01m

Cape Town Intl

Tue 3/31

6:50 pm-3:48 pm

2 stops26h 58m

$1,500

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Sat 7/11

6:33 pm-9:25 am

2 stops32h 52m

Johannesburg OR Tambo

Sun 7/19

9:15 pm-6:11 pm

2 stops26h 56m

$1,599

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Fri 5/15

2:49 pm-11:00 am

2 stops38h 11m

Cape Town Intl

Thu 5/28

6:50 pm-6:11 pm

2 stops29h 21m

$1,651

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 5/19

7:00 am-6:30 pm

1 stop29h 30m

Johannesburg OR Tambo

Wed 6/10

10:00 pm-5:01 pm

2 stops25h 01m

$1,656

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Tue 3/10

3:13 pm-9:55 pm

2 stops24h 42m

Cape Town Intl

Tue 3/31

8:05 pm-9:16 am

1 stop19h 11m

$1,692

KnoxvilleJohannesburg

TYS - JNB

TYSJNB

Knoxville McGhee Tyson

Tue 5/19

7:00 am-3:55 am

3 stops38h 55m

Johannesburg OR Tambo

Wed 6/10

2:30 pm-2:23 pm

3 stops29h 53m

$1,716

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Tue 5/19

5:06 pm-11:00 am

2 stops35h 54m

Cape Town Intl

Sun 5/31

6:50 pm-6:11 pm

2 stops29h 21m

$1,786

KnoxvilleCape Town

TYS - CPT

TYSCPT

Knoxville McGhee Tyson

Tue 5/19

1:52 pm-2:35 pm

2 stops42h 43m

Cape Town Intl

Sun 5/31

1:50 pm-5:01 pm

3 stops33h 11m

$1,830

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to South Africa from

How to get the cheapest flight ticket from Knoxville to South Africa

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to South Africa?

Etihad Airways, Delta, and Air Canada are the most popular carriers operating from Knoxville McGhee Tyson to South Africa

Cheap Knoxville to South Africa flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to South Africa

Fastest flight time

28h 37m

Direct flights

None
The fastest flight from Knoxville to South Africa takes 28h 37m
There are no direct flights from Knoxville to South Africa. There are no popular flight routes from Knoxville to South Africa.
  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to South Africa?

    Prices for flights from Knoxville McGhee Tyson Airport to South Africa are updated daily.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to South Africa?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to South Africa.

  • What documentation or ID do you need to fly to South Africa?

    The necessary travel and health documents for your South Africa trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to South Africa?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Knoxville to South Africa. momondo saves you time and could save you money on your trip.

Can I find flights from Knoxville to South Africa with flexible booking policies on momondo?

momondo does allow users to show only those flights to South Africa from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to South Africa?

Once you have performed a search for Knoxville to South Africa flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to South Africa right now. Can momondo alert me if prices change?

If you are simply researching potential flights to South Africa, momondo offers a useful price alert feature which will track prices for flights to South Africa from Knoxville and alert you when they change.

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Sat 2/28
Sat 3/7

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