What airlines fly to Sioux Falls?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Sioux Falls from Knoxville according to our data. American Airlines is the first choice among our users, with 75% of people opting to fly with this airline when traveling to Sioux Falls. Keep in mind that there are 3 different airlines that fly to Sioux Falls on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?

As of August 2026, there are 3 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.

What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?

The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$317 Cheap Flights from Knoxville to Sioux Falls in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Sioux Falls

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Cheap round-trip flights

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8:30 pm - 12:39 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

5h 09m1 stop Chicago O'Hare Intl

3:26 pm - 11:47 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

7h 21m1 stop Chicago O'Hare Intl

$317American Airlines

Sat, Nov 7 - Sun, Nov 15

7:30 am - 12:16 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

5h 46m1 stop Dallas/Fort Worth

6:00 am - 1:53 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

6h 53m1 stop Dallas/Fort Worth

$317American Airlines

Thu, Sep 17 - Tue, Sep 22

4:38 pm - 7:59 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

4h 21m1 stop Atlanta Hartsfield-Jackson

5:30 am - 11:11 amFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

4h 41m1 stop Atlanta Hartsfield-Jackson

$319Delta

Fri, Aug 28 - Sun, Aug 30

11:40 am - 4:53 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

6h 13m1 stop Chicago O'Hare Intl

6:24 am - 12:51 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

5h 27m1 stop Chicago O'Hare Intl

$319American Airlines

Fri, Aug 28 - Sun, Aug 30

6:35 am - 12:38 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

7h 03m1 stop Minneapolis St Paul

5:30 am - 11:11 amFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

4h 41m1 stop Atlanta Hartsfield-Jackson

$334Delta

Fri, Aug 28 - Mon, Aug 31

4:38 pm - 7:59 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

4h 21m1 stop Atlanta Hartsfield-Jackson

5:30 am - 11:11 amFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

4h 41m1 stop Atlanta Hartsfield-Jackson

$334Delta

Fri, Aug 28 - Sun, Aug 30

2:21 pm - 11:22 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

10h 01m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

7:47 am - 1:17 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

4h 30m1 stop Chicago O'Hare Intl

$339United Airlines

Fri, Aug 28 - Mon, Aug 31

6:02 pm - 11:12 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

6h 10m1 stop Chicago O'Hare Intl

1:33 pm - 12:23 amFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

9h 50m2 stops Denver Intl Chicago O'Hare Intl

$380United Airlines

Thu, Sep 17 - Tue, Sep 22

9:28 pm - 9:19 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

12h 51m1 stop Tampa St. Petersburg

12:41 pm - 3:38 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

25h 57m2 stops Las Vegas Harry Reid Intl Phoenix Sky Harbor Intl

$437Multiple Airlines

Thu, Oct 8 - Sun, Oct 11

9:28 pm - 9:19 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

12h 51m1 stop Tampa St. Petersburg

12:41 pm - 1:57 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

24h 16m1 stop Las Vegas Harry Reid Intl

$498Allegiant Air

Thu, Oct 8 - Sun, Oct 11

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United Airlines flights from Knoxville to Sioux Falls

Our best United Airlines deals on Knoxville to Sioux Falls flight tickets

United Airlines

Aug 28

TYS2:21 pmKnoxville McGhee Tyson

10h 01m

2 stops

FSD11:22 pmSioux Falls Joe Foss Field

Aug 31

FSD7:47 amSioux Falls Joe Foss Field

4h 30m

1 stop

TYS1:17 pmKnoxville McGhee Tyson

$339

United Airlines

Sep 17

TYS6:02 pmKnoxville McGhee Tyson

6h 10m

1 stop

FSD11:12 pmSioux Falls Joe Foss Field

Sep 22

FSD1:33 pmSioux Falls Joe Foss Field

9h 50m

2 stops

TYS12:23 amKnoxville McGhee Tyson

$380

United Airlines

Aug 28

TYS4:50 pmKnoxville McGhee Tyson

7h 54m

1 stop

FSD11:44 pmSioux Falls Joe Foss Field

Sep 7

FSD7:47 amSioux Falls Joe Foss Field

4h 30m

1 stop

TYS1:17 pmKnoxville McGhee Tyson

$400

American Airlines flights from Knoxville to Sioux Falls

Our best American Airlines deals on Knoxville to Sioux Falls flight tickets

American Airlines

Sep 17

TYS7:30 amKnoxville McGhee Tyson

5h 46m

1 stop

FSD12:16 pmSioux Falls Joe Foss Field

Sep 22

FSD6:00 amSioux Falls Joe Foss Field

6h 53m

1 stop

TYS1:53 pmKnoxville McGhee Tyson

$317

American Airlines

Oct 15

TYS6:55 pmKnoxville McGhee Tyson

6h 46m

1 stop

FSD12:41 amSioux Falls Joe Foss Field

Oct 20

FSD7:03 amSioux Falls Joe Foss Field

10h 40m

2 stops

TYS6:43 pmKnoxville McGhee Tyson

$322

American Airlines

Aug 28

TYS12:09 pmKnoxville McGhee Tyson

9h 22m

2 stops

FSD8:31 pmSioux Falls Joe Foss Field

Aug 30

FSD6:24 amSioux Falls Joe Foss Field

5h 27m

1 stop

TYS12:51 pmKnoxville McGhee Tyson

$324

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Sat 11/7

8:30 pm-12:39 am

1 stop5h 09m

Sioux Falls Joe Foss Field

Sun 11/15

3:26 pm-11:47 pm

1 stop7h 21m

$317

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 9/17

7:30 am-12:16 pm

1 stop5h 46m

Sioux Falls Joe Foss Field

Tue 9/22

6:00 am-1:53 pm

1 stop6h 53m

$317

Quickest round-trip

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Fri 8/28

4:38 pm-7:59 pm

1 stop4h 21m

Sioux Falls Joe Foss Field

Sun 8/30

5:30 am-11:11 am

1 stop4h 41m

$319

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Fri 8/28

11:40 am-4:53 pm

1 stop6h 13m

Sioux Falls Joe Foss Field

Sun 8/30

6:24 am-12:51 pm

1 stop5h 27m

$319

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Fri 8/28

6:35 am-12:38 pm

1 stop7h 03m

Sioux Falls Joe Foss Field

Mon 8/31

5:30 am-11:11 am

1 stop4h 41m

$334

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Fri 8/28

4:38 pm-7:59 pm

1 stop4h 21m

Sioux Falls Joe Foss Field

Sun 8/30

5:30 am-11:11 am

1 stop4h 41m

$334

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Fri 8/28

2:21 pm-11:22 pm

2 stops10h 01m

Sioux Falls Joe Foss Field

Mon 8/31

7:47 am-1:17 pm

1 stop4h 30m

$339

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 9/17

6:02 pm-11:12 pm

1 stop6h 10m

Sioux Falls Joe Foss Field

Tue 9/22

1:33 pm-12:23 am

2 stops9h 50m

$380

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 10/8

9:28 pm-9:19 am

1 stop12h 51m

Sioux Falls Joe Foss Field

Sun 10/11

12:41 pm-3:38 pm

2 stops25h 57m

$437

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 10/8

9:28 pm-9:19 am

1 stop12h 51m

Sioux Falls Joe Foss Field

Sun 10/11

12:41 pm-1:57 pm

1 stop24h 16m

$498

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Sioux Falls

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Knoxville and Sioux Falls?

Prices are currently low for flights on this route.

Typical prices usually range from $385 to $508.
The lowest price recently found on this route was $317.

What is the cheapest month to fly to Sioux Falls?

The cheapest month to fly to Sioux Falls from Knoxville is in February. Flight prices, which tend to average around $269, are often lower during this time because this is during the off-season. If you’re not able to fly to Sioux Falls in February, then April is your next best option. Flight prices from Knoxville to Sioux Falls during April average around $288.

Can stopping save me money on Knoxville to Sioux Falls flights?

You could potentially save up to 31% on your flight if you consider stops on a Knoxville to Sioux Falls flight.

When to book flights from Knoxville to Sioux Falls

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Sioux Falls according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Sioux Falls (TYS to FSD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Sioux Falls

Fastest flight time	4h 21m
Direct flights	None

The fastest flight from Knoxville to Sioux Falls takes 4h 21m

There are no direct flights from Knoxville to Sioux Falls. There are no popular flight routes from Knoxville to Sioux Falls.

Search flight deals

Frequently asked questions about flying from Knoxville to Sioux Falls

How far is Knoxville McGhee Tyson to Sioux Falls Joe Foss Field by plane?
A flight from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field will travel around 856.6 mi. A reasonable flight in good conditions will take 4h 21m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?
As of August 2026, there are 3 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.
What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?
The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Knoxville to Sioux Falls?
momondo data reveals that the most frequently booked airline on the route from Knoxville to Sioux Falls is American Airlines, representing 55% of all bookings. The subsequent popular airlines are Delta at 23% and United Airlines at 21%.

Best airlines flying from Knoxville to Sioux Falls

Compare and see reviews for airlines that fly from Knoxville to Sioux Falls with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $269	Free Cancellation	Rating 7.4 10,095 reviews	Search United Airlines flights
American Airlines	PriceFrom $288	Free Cancellation	Rating 7.1 11,897 reviews	Search American Airlines flights
Delta	PriceFrom $339	Free Cancellation	Rating 7.8 8,497 reviews	Search Delta flights

Yankton

Marshall

Worthington

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Why should I use momondo to find a flight deal from Knoxville to Sioux Falls?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Sioux Falls from Knoxville.

Can I find flights from Knoxville to Sioux Falls with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Sioux Falls from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Sioux Falls?

Once all potential Knoxville to Sioux Falls flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Sioux Falls right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Sioux Falls now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Sioux Falls and let you know when they change.

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Cheap flights from Knoxville to Sioux Falls from $317

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Knoxville to Sioux Falls

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American Airlines flights from Knoxville to Sioux Falls

Our best American Airlines deals on Knoxville to Sioux Falls flight tickets

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How to get the cheapest flight ticket from Knoxville to Sioux Falls

What is the typical price of a round-trip flight between Knoxville and Sioux Falls?

What is the cheapest month to fly to Sioux Falls?

Can stopping save me money on Knoxville to Sioux Falls flights?

What airlines fly to Sioux Falls?

When to book flights from Knoxville to Sioux Falls

Cheap Knoxville to Sioux Falls (TYS to FSD) flight deals and tips

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Frequently asked questions about flying from Knoxville to Sioux Falls

Best airlines flying from Knoxville to Sioux Falls

Compare and see reviews for airlines that fly from Knoxville to Sioux Falls with momondo

Traveling to a place near Sioux Falls?

Why use momondo?

An easier way to manage your Sioux Falls trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

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Airlines are sorted and displayed according to clicks in the past 7 days on momondo

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List of cabin classes available on flights landing in Sioux Falls. Availability may vary depending on flight origin and airline.

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