How many flights depart from Knoxville to Sioux Falls on average per week?

As of September 2026, 1 flights take off from Knoxville and land in Sioux Falls each week. The most common flight departure day for this route is Wed, with 100% of weekly flights taking off on this day.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field?

Allegiant Air is the most popular carrier operating from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?

As of September 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.

What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?

The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$215 Cheap Flights from Knoxville to Sioux Falls in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Sioux Falls

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7:25 am - 12:13 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

5h 48m1 stop Dallas/Fort Worth

6:00 am - 2:05 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

7h 05m1 stop Dallas/Fort Worth

$330American Airlines

Tue, Oct 20 - Tue, Nov 3

7:00 am - 4:29 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

10h 29m1 stop Orlando Sanford Intl

7:14 pm - 7:59 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

23h 45m1 stop Orlando Sanford Intl

$330Allegiant Air

Thu, Nov 12 - Sun, Nov 15

6:00 am - 12:13 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

7h 13m1 stop Dallas/Fort Worth

7:00 am - 6:44 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

10h 44m2 stops Chicago O'Hare Intl Charlotte Douglas

$336American Airlines

Tue, Oct 20 - Tue, Nov 3

7:50 am - 12:07 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

5h 17m1 stop Chicago O'Hare Intl

7:00 am - 1:59 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

5h 59m1 stop Dallas/Fort Worth

$339American Airlines

Thu, Jan 7 - Mon, Jan 11

2:49 pm - 8:54 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

7h 05m1 stop Dallas/Fort Worth

5:11 am - 4:49 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

10h 38m2 stops Chicago O'Hare Intl Charlotte Douglas

$344American Airlines

Thu, Jan 7 - Mon, Jan 11

12:30 pm - 7:21 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

7h 51m2 stops Charlotte Douglas Chicago O'Hare Intl

5:11 am - 4:49 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

10h 38m2 stops Chicago O'Hare Intl Charlotte Douglas

$349American Airlines

Thu, Jan 7 - Mon, Jan 11

5:05 pm - 11:44 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

7h 39m1 stop Denver Intl

1:20 pm - 10:32 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

8h 12m1 stop Denver Intl

$439United Airlines

Fri, Oct 30 - Mon, Nov 2

10:43 am - 8:04 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

10h 21m2 stops Chicago O'Hare Intl Denver Intl

1:20 pm - 10:32 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

8h 12m1 stop Denver Intl

$444United Airlines

Fri, Oct 30 - Mon, Nov 2

7:00 am - 4:29 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

10h 29m1 stop Orlando Sanford Intl

7:14 pm - 2:07 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

17h 53m2 stops Orlando Sanford Intl Key West

$449Allegiant Air

Thu, Nov 12 - Sun, Nov 15

5:05 pm - 11:44 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

7h 39m1 stop Denver Intl

1:20 pm - 10:32 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

8h 12m1 stop Denver Intl

$479United Airlines

Fri, Oct 30 - Mon, Nov 2

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American Airlines flights from Knoxville to Sioux Falls

Our best American Airlines deals on Knoxville to Sioux Falls flight tickets

American Airlines

Oct 20

TYS7:25 amKnoxville McGhee Tyson

5h 48m

1 stop

FSD12:13 pmSioux Falls Joe Foss Field

Nov 3

FSD6:00 amSioux Falls Joe Foss Field

7h 05m

1 stop

TYS2:05 pmKnoxville McGhee Tyson

$330

American Airlines

Oct 20

TYS6:00 amKnoxville McGhee Tyson

7h 13m

1 stop

FSD12:13 pmSioux Falls Joe Foss Field

Nov 3

FSD7:00 amSioux Falls Joe Foss Field

10h 44m

2 stops

TYS6:44 pmKnoxville McGhee Tyson

$336

American Airlines

Jan 7

TYS7:50 amKnoxville McGhee Tyson

5h 17m

1 stop

FSD12:07 pmSioux Falls Joe Foss Field

Jan 11

FSD7:00 amSioux Falls Joe Foss Field

5h 59m

1 stop

TYS1:59 pmKnoxville McGhee Tyson

$339

United Airlines flights from Knoxville to Sioux Falls

Our best United Airlines deals on Knoxville to Sioux Falls flight tickets

United Airlines

Oct 30

TYS5:05 pmKnoxville McGhee Tyson

7h 39m

1 stop

FSD11:44 pmSioux Falls Joe Foss Field

Nov 2

FSD1:20 pmSioux Falls Joe Foss Field

8h 12m

1 stop

TYS10:32 pmKnoxville McGhee Tyson

$439

United Airlines

Oct 30

TYS10:43 amKnoxville McGhee Tyson

10h 21m

2 stops

FSD8:04 pmSioux Falls Joe Foss Field

Nov 2

FSD1:20 pmSioux Falls Joe Foss Field

8h 12m

1 stop

TYS10:32 pmKnoxville McGhee Tyson

$444

United Airlines

Oct 30

TYS5:05 pmKnoxville McGhee Tyson

7h 39m

1 stop

FSD11:44 pmSioux Falls Joe Foss Field

Nov 2

FSD1:20 pmSioux Falls Joe Foss Field

8h 12m

1 stop

TYS10:32 pmKnoxville McGhee Tyson

$479

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Tue 10/20

7:25 am-12:13 pm

1 stop5h 48m

Sioux Falls Joe Foss Field

Tue 11/3

6:00 am-2:05 pm

1 stop7h 05m

$330

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 11/12

7:00 am-4:29 pm

1 stop10h 29m

Sioux Falls Joe Foss Field

Sun 11/15

7:14 pm-7:59 pm

1 stop23h 45m

$330

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Tue 10/20

6:00 am-12:13 pm

1 stop7h 13m

Sioux Falls Joe Foss Field

Tue 11/3

7:00 am-6:44 pm

2 stops10h 44m

$336

Quickest round-trip

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 1/7

7:50 am-12:07 pm

1 stop5h 17m

Sioux Falls Joe Foss Field

Mon 1/11

7:00 am-1:59 pm

1 stop5h 59m

$339

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 1/7

2:49 pm-8:54 pm

1 stop7h 05m

Sioux Falls Joe Foss Field

Mon 1/11

5:11 am-4:49 pm

2 stops10h 38m

$344

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 1/7

12:30 pm-7:21 pm

2 stops7h 51m

Sioux Falls Joe Foss Field

Mon 1/11

5:11 am-4:49 pm

2 stops10h 38m

$349

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Fri 10/30

5:05 pm-11:44 pm

1 stop7h 39m

Sioux Falls Joe Foss Field

Mon 11/2

1:20 pm-10:32 pm

1 stop8h 12m

$439

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Fri 10/30

10:43 am-8:04 pm

2 stops10h 21m

Sioux Falls Joe Foss Field

Mon 11/2

1:20 pm-10:32 pm

1 stop8h 12m

$444

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 11/12

7:00 am-4:29 pm

1 stop10h 29m

Sioux Falls Joe Foss Field

Sun 11/15

7:14 pm-2:07 pm

2 stops17h 53m

$449

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Fri 10/30

5:05 pm-11:44 pm

1 stop7h 39m

Sioux Falls Joe Foss Field

Mon 11/2

1:20 pm-10:32 pm

1 stop8h 12m

$479

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Sioux Falls

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the typical price of a round-trip flight between Knoxville and Sioux Falls?

Prices are currently low for flights on this route.

Typical prices usually range from $486 to $615.
The lowest price recently found on this route was $330.

What is the cheapest month to fly to Sioux Falls?

The cheapest month to fly to Sioux Falls from Knoxville is in February. Flight prices, which tend to average around $269, are often lower during this time because this is during the off-season. If you’re not able to fly to Sioux Falls in February, then April is your next best option. Flight prices from Knoxville to Sioux Falls during April average around $288.

When to book flights from Knoxville to Sioux Falls

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Sioux Falls according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Sioux Falls (TYS to FSD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Sioux Falls

Best Price Found	$215
Fastest flight time	6h 08m
Direct flights	None

The best one-way flight to Sioux Falls from Knoxville in the past 72 hours is $215. The best round-trip flight deal from Knoxville to Sioux Falls found on momondo in the last 72 hours is $330.

The fastest flight from Knoxville to Sioux Falls takes 6h 08m

There are no direct flights from Knoxville to Sioux Falls. There are no popular flight routes from Knoxville to Sioux Falls.

Search flight deals

Frequently asked questions about flying from Knoxville to Sioux Falls

How far is Knoxville McGhee Tyson to Sioux Falls Joe Foss Field by plane?
A flight from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field will travel around 856.6 mi. A reasonable flight in good conditions will take 6h 08m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?
As of September 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.
What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?
The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Knoxville to Sioux Falls?
momondo data reveals that the most frequently booked airline on the route from Knoxville to Sioux Falls is American Airlines, representing 70% of all bookings. The subsequent popular airline is Delta at 30%.

Best airlines flying from Knoxville to Sioux Falls

Compare and see reviews for airlines that fly from Knoxville to Sioux Falls with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $288	Free Cancellation	Rating 7.0 12,075 reviews		Search American Airlines flights
Delta	PriceFrom $339	Free Cancellation	Rating 7.8 8,595 reviews		Search Delta flights

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Why should I use momondo to find a flight deal from Knoxville to Sioux Falls?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Sioux Falls from Knoxville.

Can I find flights from Knoxville to Sioux Falls with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Sioux Falls from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Sioux Falls?

Once all potential Knoxville to Sioux Falls flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Sioux Falls right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Sioux Falls now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Sioux Falls and let you know when they change.

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Cheap flights from Knoxville to Sioux Falls from $215

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 11/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Knoxville to Sioux Falls

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How to get the cheapest flight ticket from Knoxville to Sioux Falls

What is the typical price of a round-trip flight between Knoxville and Sioux Falls?

What is the cheapest month to fly to Sioux Falls?

What is the cheapest airline that flies from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field?

How many flights depart from Knoxville to Sioux Falls on average per week?

When to book flights from Knoxville to Sioux Falls

Cheap Knoxville to Sioux Falls (TYS to FSD) flight deals and tips

Best Price Found

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Frequently asked questions about flying from Knoxville to Sioux Falls

Best airlines flying from Knoxville to Sioux Falls

Compare and see reviews for airlines that fly from Knoxville to Sioux Falls with momondo

Traveling to a place near Sioux Falls?

Why use momondo?

An easier way to manage your Sioux Falls trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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List of cabin classes available on flights landing in Sioux Falls. Availability may vary depending on flight origin and airline.

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