What is the cheapest airline that flies from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field?

American Airlines and Allegiant Air are the most popular carriers operating from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?

As of November 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.

What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?

The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$289 Cheap Flights from Knoxville to Sioux Falls in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Sioux Falls

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

5:40 pm - 9:37 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

4h 57m1 stop Chicago O'Hare Intl

1:20 pm - 10:32 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

8h 12m1 stop Denver Intl

$369United Airlines

Thu, Nov 19 - Mon, Nov 23

8:50 pm - 12:48 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

4h 58m1 stop Chicago O'Hare Intl

6:00 am - 4:36 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

9h 36m2 stops Dallas/Fort Worth Charlotte Douglas

$384American Airlines

Thu, Nov 19 - Mon, Nov 23

8:50 am - 7:10 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

11h 20m2 stops Charlotte Douglas Chicago O'Hare Intl

7:07 am - 5:35 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

9h 28m2 stops Chicago O'Hare Intl Charlotte Douglas

$389American Airlines

Thu, Nov 19 - Mon, Nov 23

6:01 am - 10:44 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

5h 43m1 stop Chicago O'Hare Intl

9:45 am - 4:54 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

6h 09m1 stop Chicago O'Hare Intl

$449United Airlines

Thu, Jan 7 - Mon, Jan 11

6:01 am - 4:20 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

11h 19m2 stops Chicago O'Hare Intl Denver Intl

9:45 am - 4:54 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

6h 09m1 stop Chicago O'Hare Intl

$454United Airlines

Thu, Jan 7 - Mon, Jan 11

10:45 am - 8:37 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

10h 52m2 stops Chicago O'Hare Intl Denver Intl

7:30 am - 9:59 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

13h 29m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

$459United Airlines

Thu, Jan 7 - Mon, Jan 11

8:50 pm - 12:44 amTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

4h 54m1 stop Chicago O'Hare Intl

7:36 pm - 10:58 amFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

14h 22m1 stop Chicago O'Hare Intl

$632American Airlines

Wed, Nov 25 - Mon, Nov 30

4:00 pm - 7:56 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

4h 56m1 stop Atlanta Hartsfield-Jackson

5:25 am - 1:55 pmFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

7h 30m1 stop Atlanta Hartsfield-Jackson

$659Delta

Tue, Nov 24 - Sun, Nov 29

4:00 pm - 7:56 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

4h 56m1 stop Atlanta Hartsfield-Jackson

5:25 am - 11:28 amFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

5h 03m1 stop Atlanta Hartsfield-Jackson

$669Delta

Tue, Nov 24 - Sun, Nov 29

5:40 am - 12:17 pmTYS Knoxville McGhee Tyson-FSD Sioux Falls Joe Foss Field

7h 37m2 stops Atlanta Hartsfield-Jackson Minneapolis St Paul

5:25 am - 11:28 amFSD Sioux Falls Joe Foss Field-TYS Knoxville McGhee Tyson

5h 03m1 stop Atlanta Hartsfield-Jackson

$774Delta

Tue, Nov 24 - Sun, Nov 29

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

United Airlines flights from Knoxville to Sioux Falls

Our best United Airlines deals on Knoxville to Sioux Falls flight tickets

United Airlines

Nov 19

TYS5:40 pmKnoxville McGhee Tyson

4h 57m

1 stop

FSD9:37 pmSioux Falls Joe Foss Field

Nov 23

FSD1:20 pmSioux Falls Joe Foss Field

8h 12m

1 stop

TYS10:32 pmKnoxville McGhee Tyson

$369

United Airlines

Jan 7

TYS6:01 amKnoxville McGhee Tyson

5h 43m

1 stop

FSD10:44 amSioux Falls Joe Foss Field

Jan 11

FSD9:45 amSioux Falls Joe Foss Field

6h 09m

1 stop

TYS4:54 pmKnoxville McGhee Tyson

$449

United Airlines

Jan 7

TYS6:01 amKnoxville McGhee Tyson

11h 19m

2 stops

FSD4:20 pmSioux Falls Joe Foss Field

Jan 11

FSD9:45 amSioux Falls Joe Foss Field

6h 09m

1 stop

TYS4:54 pmKnoxville McGhee Tyson

$454

American Airlines flights from Knoxville to Sioux Falls

Our best American Airlines deals on Knoxville to Sioux Falls flight tickets

American Airlines

Nov 19

TYS8:50 pmKnoxville McGhee Tyson

4h 58m

1 stop

FSD12:48 amSioux Falls Joe Foss Field

Nov 23

FSD6:00 amSioux Falls Joe Foss Field

9h 36m

2 stops

TYS4:36 pmKnoxville McGhee Tyson

$384

American Airlines

Nov 19

TYS8:50 amKnoxville McGhee Tyson

11h 20m

2 stops

FSD7:10 pmSioux Falls Joe Foss Field

Nov 23

FSD7:07 amSioux Falls Joe Foss Field

9h 28m

2 stops

TYS5:35 pmKnoxville McGhee Tyson

$389

American Airlines

Nov 25

TYS8:50 pmKnoxville McGhee Tyson

4h 54m

1 stop

FSD12:44 amSioux Falls Joe Foss Field

Nov 30

FSD7:36 pmSioux Falls Joe Foss Field

14h 22m

1 stop

TYS10:58 amKnoxville McGhee Tyson

$632

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 11/19

5:40 pm-9:37 pm

1 stop4h 57m

Sioux Falls Joe Foss Field

Mon 11/23

1:20 pm-10:32 pm

1 stop8h 12m

$369

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 11/19

8:50 pm-12:48 am

1 stop4h 58m

Sioux Falls Joe Foss Field

Mon 11/23

6:00 am-4:36 pm

2 stops9h 36m

$384

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 11/19

8:50 am-7:10 pm

2 stops11h 20m

Sioux Falls Joe Foss Field

Mon 11/23

7:07 am-5:35 pm

2 stops9h 28m

$389

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 1/7

6:01 am-10:44 am

1 stop5h 43m

Sioux Falls Joe Foss Field

Mon 1/11

9:45 am-4:54 pm

1 stop6h 09m

$449

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 1/7

6:01 am-4:20 pm

2 stops11h 19m

Sioux Falls Joe Foss Field

Mon 1/11

9:45 am-4:54 pm

1 stop6h 09m

$454

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Thu 1/7

10:45 am-8:37 pm

2 stops10h 52m

Sioux Falls Joe Foss Field

Mon 1/11

7:30 am-9:59 pm

2 stops13h 29m

$459

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Wed 11/25

8:50 pm-12:44 am

1 stop4h 54m

Sioux Falls Joe Foss Field

Mon 11/30

7:36 pm-10:58 am

1 stop14h 22m

$632

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Tue 11/24

4:00 pm-7:56 pm

1 stop4h 56m

Sioux Falls Joe Foss Field

Sun 11/29

5:25 am-1:55 pm

1 stop7h 30m

$659

Quickest round-trip

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Tue 11/24

4:00 pm-7:56 pm

1 stop4h 56m

Sioux Falls Joe Foss Field

Sun 11/29

5:25 am-11:28 am

1 stop5h 03m

$669

KnoxvilleSioux Falls

TYS Knoxville McGhee Tyson - FSD Sioux Falls Joe Foss Field

TYSFSD

Knoxville McGhee Tyson

Tue 11/24

5:40 am-12:17 pm

2 stops7h 37m

Sioux Falls Joe Foss Field

Sun 11/29

5:25 am-11:28 am

1 stop5h 03m

$774

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Sioux Falls

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Sioux Falls?

The cheapest month to fly to Sioux Falls from Knoxville is in February. Flight prices, which tend to average around $269, are often lower during this time because this is during the off-season. If you’re not able to fly to Sioux Falls in February, then April is your next best option. Flight prices from Knoxville to Sioux Falls during April average around $288.

When to book flights from Knoxville to Sioux Falls

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Sioux Falls according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Sioux Falls (TYS to FSD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Sioux Falls

Best Price Found	$289
Fastest flight time	4h 56m
Direct flights	None

The best one-way flight to Sioux Falls from Knoxville in the past 72 hours is $289. The best round-trip flight deal from Knoxville to Sioux Falls found on momondo in the last 72 hours is $369.

The fastest flight from Knoxville to Sioux Falls takes 4h 56m

There are no direct flights from Knoxville to Sioux Falls. There are no popular flight routes from Knoxville to Sioux Falls.

Search flight deals

Frequently asked questions about flying from Knoxville to Sioux Falls

How far is Knoxville McGhee Tyson to Sioux Falls Joe Foss Field by plane?
A flight from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field will travel around 856.6 mi. A reasonable flight in good conditions will take 4h 56m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?
As of November 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Sioux Falls Joe Foss Field Airport.
What documentation or ID do you need to fly to Sioux Falls Joe Foss Field Airport?
The travel and health documents you'll need for your trip to Sioux Falls Joe Foss Field Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Sioux Falls Joe Foss Field Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Knoxville to Sioux Falls?
momondo data reveals that the most frequently booked airline on the route from Knoxville to Sioux Falls is American Airlines, representing 68% of all bookings. The subsequent popular airline is Delta at 32%.

Best airlines flying from Knoxville to Sioux Falls

Compare and see reviews for airlines that fly from Knoxville to Sioux Falls with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $288	Free Cancellation	Rating 7.0 12,228 reviews		Search American Airlines flights
Delta	PriceFrom $339	Free Cancellation	Rating 7.8 8,698 reviews		Search Delta flights

Yankton

Worthington

Marshall

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Sioux Falls?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Sioux Falls from Knoxville.

Can I find flights from Knoxville to Sioux Falls with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Sioux Falls from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Sioux Falls?

Once all potential Knoxville to Sioux Falls flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Sioux Falls right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Sioux Falls now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Sioux Falls and let you know when they change.

An easier way to manage your Sioux Falls trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Start using Trips

Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

1 adult

Tue 12/8

Tue 12/15

Email me momondo's favorite deals

By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to the United States

Nearby airports

Airlines

Cabin classes

Other United States destinations

Other flights from Knoxville

Complete your trip

Feeling lucky

Airports servicing South Dakota

Cheap flights from Knoxville to Sioux Falls from $289

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Sioux Falls departing on 11/30. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

Find the cheapest flights from Knoxville to Sioux Falls

Cheap round-trip flights

Cheap one-way flights

Cheap last minute flights

Big names and deals

Big names and deals

Filter for what you want

Filter for what you want

Trusted and free

Trusted and free

Price Alerts

Price Alerts

United Airlines flights from Knoxville to Sioux Falls

Our best United Airlines deals on Knoxville to Sioux Falls flight tickets

American Airlines flights from Knoxville to Sioux Falls

Our best American Airlines deals on Knoxville to Sioux Falls flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Knoxville to Sioux Falls that are best for you.

See travel insights to Sioux Falls from

How to get the cheapest flight ticket from Knoxville to Sioux Falls

What is the cheapest month to fly to Sioux Falls?

What is the cheapest airline that flies from Knoxville McGhee Tyson to Sioux Falls Joe Foss Field?

When to book flights from Knoxville to Sioux Falls

Cheap Knoxville to Sioux Falls (TYS to FSD) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Knoxville to Sioux Falls

Best airlines flying from Knoxville to Sioux Falls

Compare and see reviews for airlines that fly from Knoxville to Sioux Falls with momondo

Traveling to a place near Sioux Falls?

Why use momondo?

An easier way to manage your Sioux Falls trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing South Dakota

Fly your favorite airline to Sioux Falls

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Sioux Falls

List of cabin classes available on flights landing in Sioux Falls. Availability may vary depending on flight origin and airline.

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo

Fly to other destinations from Knoxville

According to popular flight searches on momondo this year

Complete your trip to Sioux Falls

Explore popular destinations other users love

According to popular flight searches on momondo this year