What airlines fly to Charleston?

American Airlines, Delta and Allegiant Air are the top three most popular airlines that fly to Charleston from Knoxville according to our data. American Airlines is the first choice among our users, with 67% of people opting to fly with this airline when traveling to Charleston. Keep in mind that there are 3 different airlines that fly to Charleston on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Charleston?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Charleston

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Charleston Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Charleston Airport are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Charleston Airport?

As of August 2025, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Charleston Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Charleston Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Charleston Airport.

What documentation or ID do you need to fly to Charleston Airport?

The travel and health documents you'll need for your trip to Charleston Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Charleston Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$113 Cheap Flights from Knoxville to Charleston in 2025

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Round-trip

One-way

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Cheap round-trip flights

7:15 am - 5:07 pmTYS-CHS

9h 52m1 stop

12:08 pm - 11:55 amCHS-TYS

23h 47m2 stops

$255

Find Deal

vie., sep. 5 - dom., sep. 7

7:15 am - 7:04 pmTYS-CHS

11h 49m1 stop

10:30 am - 8:11 pmCHS-TYS

9h 41m1 stop

$261

Find Deal

mié., oct. 15 - dom., oct. 19

10:54 am - 9:33 amTYS-CHS

22h 39m2 stops

8:17 pm - 10:34 amCHS-TYS

14h 17m1 stop

$262

Find Deal

mié., ago. 20 - jue., ago. 21

7:15 am - 5:07 pmTYS-CHS

9h 52m1 stop

9:40 pm - 7:42 pmCHS-TYS

22h 02m2 stops

$271

Find Deal

vie., sep. 5 - dom., sep. 7

10:54 am - 9:33 amTYS-CHS

22h 39m2 stops

8:17 pm - 10:34 amCHS-TYS

14h 17m1 stop

$277

Find Deal

mié., ago. 20 - dom., ago. 24

6:08 pm - 9:22 pmTYS-CHS

3h 14m1 stop

8:02 am - 1:10 pmCHS-TYS

5h 08m1 stop

$297Delta

Find Deal

mié., sep. 17 - sáb., sep. 20

6:08 pm - 11:48 pmTYS-CHS

5h 40m1 stop

8:02 am - 1:10 pmCHS-TYS

5h 08m1 stop

$307Delta

Find Deal

sáb., sep. 13 - sáb., sep. 20

7:35 pm - 11:03 pmTYS-CHS

3h 28m1 stop

5:00 am - 8:50 amCHS-TYS

3h 50m1 stop

$367American Airlines

Find Deal

mié., ago. 20 - dom., ago. 24

5:06 am - 8:16 amTYS-CHS

3h 10m1 stop

7:28 pm - 11:03 pmCHS-TYS

3h 35m1 stop

$379American Airlines

Find Deal

lun., sep. 1 - vie., sep. 12

5:45 am - 7:08 pmTYS-CHS

13h 23m2 stops

4:34 pm - 10:11 amCHS-TYS

17h 37m1 stop

$469United Airlines

Find Deal

mar., sep. 2 - mar., sep. 9

American Airlines flights from Knoxville to Charleston

Our best American Airlines deals on Knoxville to Charleston flight tickets

American Airlines

Aug 20

TYS7:35 pmKnoxville McGhee Tyson

3h 28m

1 stop

CHS11:03 pmCharleston

Aug 24

CHS5:00 amCharleston

3h 50m

1 stop

TYS8:50 amKnoxville McGhee Tyson

$367

Find similar

American Airlines

Sep 1

TYS5:06 amKnoxville McGhee Tyson

3h 10m

1 stop

CHS8:16 amCharleston

Sep 12

CHS7:28 pmCharleston

3h 35m

1 stop

TYS11:03 pmKnoxville McGhee Tyson

$379

Find similar

American Airlines

Aug 15

TYS5:26 pmKnoxville McGhee Tyson

3h 34m

1 stop

CHS9:00 pmCharleston

Aug 17

CHS5:00 amCharleston

3h 50m

1 stop

TYS8:50 amKnoxville McGhee Tyson

$407

Find similar

Delta flights from Knoxville to Charleston

Our best Delta deals on Knoxville to Charleston flight tickets

Delta

Sep 17

TYS6:08 pmKnoxville McGhee Tyson

3h 14m

1 stop

CHS9:22 pmCharleston

Sep 20

CHS8:02 amCharleston

5h 08m

1 stop

TYS1:10 pmKnoxville McGhee Tyson

$297

Find similar

Delta

Sep 13

TYS6:08 pmKnoxville McGhee Tyson

5h 40m

1 stop

CHS11:48 pmCharleston

Sep 20

CHS8:02 amCharleston

5h 08m

1 stop

TYS1:10 pmKnoxville McGhee Tyson

$307

Find similar

Delta

Sep 1

TYS5:45 amKnoxville McGhee Tyson

3h 34m

1 stop

CHS9:19 amCharleston

Sep 11

CHS5:10 amCharleston

5h 32m

1 stop

TYS10:42 amKnoxville McGhee Tyson

$317

Find similar

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

vie. 9/5

7:15 am-5:07 pm

1 stop9h 52m

Charleston

dom. 9/7

12:08 pm-11:55 am

2 stops23h 47m

$255

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

mié. 10/15

7:15 am-7:04 pm

1 stop11h 49m

Charleston

dom. 10/19

10:30 am-8:11 pm

1 stop9h 41m

$261

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

mié. 8/20

10:54 am-9:33 am

2 stops22h 39m

Charleston

jue. 8/21

8:17 pm-10:34 am

1 stop14h 17m

$262

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

vie. 9/5

7:15 am-5:07 pm

1 stop9h 52m

Charleston

dom. 9/7

9:40 pm-7:42 pm

2 stops22h 02m

$271

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

mié. 8/20

10:54 am-9:33 am

2 stops22h 39m

Charleston

dom. 8/24

8:17 pm-10:34 am

1 stop14h 17m

$277

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

mié. 9/17

6:08 pm-9:22 pm

1 stop3h 14m

Charleston

sáb. 9/20

8:02 am-1:10 pm

1 stop5h 08m

$297

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

sáb. 9/13

6:08 pm-11:48 pm

1 stop5h 40m

Charleston

sáb. 9/20

8:02 am-1:10 pm

1 stop5h 08m

$307

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

mié. 8/20

7:35 pm-11:03 pm

1 stop3h 28m

Charleston

dom. 8/24

5:00 am-8:50 am

1 stop3h 50m

$367

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

lun. 9/1

5:06 am-8:16 am

1 stop3h 10m

Charleston

vie. 9/12

7:28 pm-11:03 pm

1 stop3h 35m

$379

KnoxvilleCharleston

TYS - CHS

TYSCHS

Knoxville McGhee Tyson

mar. 9/2

5:45 am-7:08 pm

2 stops13h 23m

Charleston

mar. 9/9

4:34 pm-10:11 am

1 stop17h 37m

$469

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How to get the cheapest flight ticket from Knoxville to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Charleston?

The cheapest month to fly to Charleston from Knoxville is in May. Flight prices, which tend to average around $366, are often lower during this time because this is during the off-season. The month of September is another great option to travel to Charleston, with average flight prices from Knoxville averaging around $366.

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Knoxville to Charleston is on a Saturday. Travelers who choose to depart for Charleston on a Saturday will often find tickets for as low as $456. The most expensive day to fly to Charleston is Monday, with ticket prices averaging around $678.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the morning when flights can be purchased for as low as $478. In the afternoon is when there is more demand to fly to Charleston, so prices are often more expensive at around $588 per ticket.

When to book flights from Knoxville to Charleston

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Charleston according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Charleston (TYS to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Charleston

Best Price Found	$113
Fastest flight time	3h 10m
Direct flights	None
Airports in Charleston	1 airport

The best one-way flight to Charleston from Knoxville in the past 72 hours is $113. The best round-trip flight deal from Knoxville to Charleston found on momondo in the last 72 hours is $255.

The fastest flight from Knoxville to Charleston takes 3h 10m

There are no direct flights from Knoxville to Charleston. Popular non-direct route for this connection is Knoxville McGhee Tyson Airport - Charleston Airport.

There is 1 airport near Charleston: Charleston (CHS)

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How far is Knoxville McGhee Tyson to Charleston by plane?
The distance between Knoxville McGhee Tyson and Charleston is about 316.2 mi. A reasonable flight in good conditions will take 3h 10m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Charleston Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Charleston Airport are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Charleston Airport?
As of August 2025, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Charleston Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Charleston Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Charleston Airport.
What documentation or ID do you need to fly to Charleston Airport?
The travel and health documents you'll need for your trip to Charleston Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Charleston Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Knoxville to Charleston?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Charleston is American Airlines (64% of total bookings). The next most popular airline is Delta (36%).

Best airlines flying from Knoxville to Charleston

Compare and see reviews for airlines that fly from Knoxville to Charleston with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $320	Free Cancellation	Rating 8.0 7,985 reviews		Search Delta flights
American Airlines	PriceFrom $336	Free Cancellation	Rating 7.2 10,000 reviews		Search American Airlines flights

Folly Beach

Isle of Palms

North Charleston

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Mount Pleasant

Summerville

Edisto Island

Walterboro

Edisto Beach

Santee

Goose Creek

Seabrook Island

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Charleston?

Finding the right flight to Charleston from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Charleston quick and easy, saving you time and money.

Can I find flights from Knoxville to Charleston with flexible booking policies on momondo?

All flight searches from Knoxville to Charleston on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Charleston?

momondo provides multiple filters to help you find the best flight to Charleston from Knoxville. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Knoxville to Charleston right now. Can momondo alert me if prices change?

Price alerts on flights to Charleston from Knoxville are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Cheap flights from Knoxville to Charleston from $113

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Charleston departing on 8/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Knoxville to Charleston

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How to get the cheapest flight ticket from Knoxville to Charleston

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Charleston?

What is the cheapest day to depart on your flight to Charleston?

The cheapest day to depart from Knoxville to Charleston is on a Saturday. Travelers who choose to depart for Charleston on a Saturday will often find tickets for as low as $456. The most expensive day to fly to Charleston is Monday, with ticket prices averaging around $678.

What is the cheapest time of day to depart on your flight to Charleston?

The cheapest time of day to fly to Charleston is in the morning when flights can be purchased for as low as $478. In the afternoon is when there is more demand to fly to Charleston, so prices are often more expensive at around $588 per ticket.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Charleston?

American Airlines, Delta, and United Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Charleston

What airlines fly to Charleston?

When to book flights from Knoxville to Charleston

Cheap Knoxville to Charleston (TYS to CHS) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Charleston

Best Price Found

Fastest flight time

Direct flights

Airports in Charleston

How far is Knoxville McGhee Tyson to Charleston by plane?

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Charleston Airport?

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Charleston Airport?

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Charleston Airport?

What documentation or ID do you need to fly to Charleston Airport?

What is the most popular airline from Knoxville to Charleston?

Best airlines flying from Knoxville to Charleston

Compare and see reviews for airlines that fly from Knoxville to Charleston with momondo

Traveling to a place near Charleston?

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Charleston?

Can I find flights from Knoxville to Charleston with flexible booking policies on momondo?

How can momondo help me find flights from Knoxville to Charleston?

I’m not ready to book a flight from Knoxville to Charleston right now. Can momondo alert me if prices change?

An easier way to manage your Charleston trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to the United States

Airports servicing South Carolina