Cheap flights from Knoxville to Chile from $465

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Chile departing on 2/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
9:10 am - 8:50 am
TYS
-
SCL
21h 40m
1 stop
United Airlines Logo
10:45 pm - 1:46 pm
SCL
-
TYS
17h 01m
1 stop
$820United Airlines
Wed, Feb 25 - Wed, Mar 4
United Airlines Logo
11:40 am - 8:50 am
TYS
-
SCL
19h 10m
1 stop
United Airlines Logo
9:45 pm - 7:55 pm
SCL
-
TYS
23h 10m
1 stop
$900United Airlines
Fri, Mar 6 - Sun, Mar 15
United Airlines Logo
11:40 am - 8:50 am
TYS
-
SCL
19h 10m
1 stop
United Airlines Logo
9:45 pm - 8:47 pm
SCL
-
TYS
48h 02m
2 stops
$922United Airlines
Fri, Mar 6 - Sun, Mar 15
United Airlines Logo
7:25 pm - 8:50 am
TYS
-
SCL
35h 25m
2 stops
United Airlines Logo
9:45 pm - 1:18 pm
SCL
-
TYS
40h 33m
2 stops
$940United Airlines
Fri, Mar 6 - Sun, Mar 15
LATAM Airlines Logo
6:41 pm - 7:00 am
TYS
-
SCL
34h 19m
2 stops
LATAM Airlines Logo
6:48 pm - 11:57 pm
SCL
-
TYS
30h 09m
3 stops
$950LATAM Airlines
Fri, Mar 6 - Sat, Mar 14
LATAM Airlines Logo
6:41 pm - 5:35 pm
TYS
-
SCL
20h 54m
2 stops
LATAM Airlines Logo
6:30 pm - 9:24 am
SCL
-
TYS
16h 54m
2 stops
$1,043LATAM Airlines
Fri, Feb 6 - Sat, Feb 14
American Airlines Logo
5:36 pm - 7:50 am
TYS
-
SCL
12h 14m
1 stop
American Airlines Logo
11:15 pm - 3:37 pm
SCL
-
TYS
18h 22m
1 stop
$1,051American Airlines
Fri, Feb 6 - Sat, Feb 14
United Airlines Logo
7:00 am - 8:50 am
TYS
-
SCL
23h 50m
3 stops
United Airlines Logo
9:45 pm - 1:18 pm
SCL
-
TYS
40h 33m
2 stops
$1,060United Airlines
Fri, Mar 6 - Sun, Mar 15
United Airlines Logo
11:40 am - 8:50 am
TYS
-
SCL
19h 10m
1 stop
United Airlines Logo
9:45 pm - 10:19 am
SCL
-
TYS
61h 34m
2 stops
$1,063United Airlines
Fri, Mar 6 - Sat, Mar 14
LATAM Airlines Logo
6:41 pm - 9:34 pm
TYS
-
SCL
24h 53m
3 stops
LATAM Airlines Logo
6:30 pm - 9:24 am
SCL
-
TYS
16h 54m
2 stops
$1,133LATAM Airlines
Fri, Feb 6 - Sat, Feb 14

United Airlines flights from Knoxville to Chile

Our best United Airlines deals on Knoxville to Chile flight tickets
United Airlines
Feb 25
TYS9:10 amKnoxville McGhee Tyson
21h 40m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 4
SCL10:45 pmSantiago Arturo Merino Benitez
17h 01m
1 stop
TYS1:46 pmKnoxville McGhee Tyson
$820
United Airlines
Mar 6
TYS11:40 amKnoxville McGhee Tyson
19h 10m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 15
SCL9:45 pmSantiago Arturo Merino Benitez
23h 10m
1 stop
TYS7:55 pmKnoxville McGhee Tyson
$900
United Airlines
Mar 6
TYS11:40 amKnoxville McGhee Tyson
19h 10m
1 stop
SCL8:50 amSantiago Arturo Merino Benitez
Mar 15
SCL9:45 pmSantiago Arturo Merino Benitez
48h 02m
2 stops
TYS8:47 pmKnoxville McGhee Tyson
$922

American Airlines flights from Knoxville to Chile

Our best American Airlines deals on Knoxville to Chile flight tickets
American Airlines
Feb 6
TYS5:36 pmKnoxville McGhee Tyson
12h 14m
1 stop
SCL7:50 amSantiago Arturo Merino Benitez
Feb 14
SCL11:15 pmSantiago Arturo Merino Benitez
18h 22m
1 stop
TYS3:37 pmKnoxville McGhee Tyson
$1,051
American Airlines
Mar 6
TYS4:29 pmKnoxville McGhee Tyson
13h 36m
1 stop
SCL8:05 amSantiago Arturo Merino Benitez
Mar 14
SCL10:15 pmSantiago Arturo Merino Benitez
20h 16m
1 stop
TYS5:31 pmKnoxville McGhee Tyson
$1,243

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Chile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Knoxville to Chile that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Wed 2/25

9:10 am-8:50 am

1 stop21h 40m

Santiago Arturo Merino Benitez

Wed 3/4

10:45 pm-1:46 pm

1 stop17h 01m

$820

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Fri 3/6

11:40 am-8:50 am

1 stop19h 10m

Santiago Arturo Merino Benitez

Sun 3/15

9:45 pm-7:55 pm

1 stop23h 10m

$900

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Fri 3/6

11:40 am-8:50 am

1 stop19h 10m

Santiago Arturo Merino Benitez

Sun 3/15

9:45 pm-8:47 pm

2 stops48h 02m

$922

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Fri 3/6

7:25 pm-8:50 am

2 stops35h 25m

Santiago Arturo Merino Benitez

Sun 3/15

9:45 pm-1:18 pm

2 stops40h 33m

$940

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Fri 3/6

6:41 pm-7:00 am

2 stops34h 19m

Santiago Arturo Merino Benitez

Sat 3/14

6:48 pm-11:57 pm

3 stops30h 09m

$950

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Fri 2/6

6:41 pm-5:35 pm

2 stops20h 54m

Santiago Arturo Merino Benitez

Sat 2/14

6:30 pm-9:24 am

2 stops16h 54m

$1,043

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Fri 2/6

5:36 pm-7:50 am

1 stop12h 14m

Santiago Arturo Merino Benitez

Sat 2/14

11:15 pm-3:37 pm

1 stop18h 22m

$1,051

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Fri 3/6

7:00 am-8:50 am

3 stops23h 50m

Santiago Arturo Merino Benitez

Sun 3/15

9:45 pm-1:18 pm

2 stops40h 33m

$1,060

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Fri 3/6

11:40 am-8:50 am

1 stop19h 10m

Santiago Arturo Merino Benitez

Sat 3/14

9:45 pm-10:19 am

2 stops61h 34m

$1,063

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Fri 2/6

6:41 pm-9:34 pm

3 stops24h 53m

Santiago Arturo Merino Benitez

Sat 2/14

6:30 pm-9:24 am

2 stops16h 54m

$1,133

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Chile from

How to get the cheapest flight ticket from Knoxville to Chile

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to Chile?

American Airlines is the most popular carrier operating from Knoxville McGhee Tyson to Chile

Cheap Knoxville to Chile flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Chile

Fastest flight time

19h 09m

Direct flights

None
The fastest flight from Knoxville to Chile takes 19h 09m
There are no direct flights from Knoxville to Chile. There are no popular flight routes from Knoxville to Chile.
  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Chile?

    Prices for flights from Knoxville McGhee Tyson Airport to Chile are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Chile?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Chile?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Chile.

  • What documentation or ID do you need to fly to Chile?

    The travel and health documents you'll need for your trip to Chile may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chile. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Knoxville to Chile

Compare and see reviews for airlines that fly from Knoxville to Chile with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $678Free CancellationRating
7.2
11,197 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Chile?

It is quick and easy to find Knoxville to Chile flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chile that suits you.

Can I find flights from Knoxville to Chile with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chile from Knoxville which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Knoxville to Chile?

Once you have performed a search for Knoxville to Chile flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Chile right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Knoxville to Chile now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chile and let you know when they change.

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1 adult
Thu 2/26
Thu 3/5

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