Cheap flights from Los Angeles to Santiago from $286

In general, October is the cheapest month to fly from Los Angeles to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $788. If you don’t want to visit Santiago in October, then you should wait until February to fly from Los Angeles, when ticket prices are also cheap, with an average price of $804.

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $911. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Thursday is $1,049.

In the afternoon is the cheapest time of day to fly from Los Angeles to Santiago when you can find flight prices for as low as $925. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,050 per ticket.

Fly from Los Angeles Los Angeles to Santiago Arturo Merino Benitez for the best Los Angeles Los Angeles - Santiago Arturo Merino Benitez flight prices

You are more likely to see cheaper flights to Santiago from Los Angeles when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $879 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Los Angeles for as low as $814 on momondo.

There are 3 cabin classes available to choose from on Los Angeles to Santiago flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 28% on your flight if you consider stops on a Los Angeles to Santiago flight.

As of July 2026, prices for Los Angeles to Santiago flights are approximately 32% more expensive when compared to flights at the same time last year.

Copa Airlines and American Airlines are the most popular carriers operating from Los Angeles Los Angeles to Santiago Arturo Merino Benitez

LATAM Airlines, Delta and Copa Airlines are the top three most popular airlines that fly to Santiago from Los Angeles according to our data. LATAM Airlines is the first choice among our users, with 65% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 5 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Historically, on average around 8% of flights between Los Angeles and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 180 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Friday has historically seen more delays on average compared to the rest of the week.

According to our data, LATAM Airlines have had the least number of delays on this route over the last 12 months; with about 7% of their flights experiencing any sort of delay.

Panama City (PTY) was the most common stop: 82% of momondo users choosing 1-stop flights on this route connected there.

Flights via Houston (IAH) offer the lowest average round-trip price of $728.

Flights connecting via Lima (LIM) have the shortest average one-way travel time: 14h 00m.

Panama City (PTY) has the shortest average layover time for this route: 1h 29m.

As of July 2026, there are 2 flights per day flying from Los Angeles to Santiago. The most common time of day flights depart is 3:00PM, with 100% of flights taking off in the afternoon.

As of July 2026, there are 20 flights per week flying from Los Angeles to Santiago. The most common day of the week flights depart is Mon, with 20% of flights taking off on this day.