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Cheap flights from Key West to Louisville from $209

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to Louisville departing on 9/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Key West to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 pm - 11:59 pm
EYW
-
SDF
5h 59m
1 stop
Delta Logo
12:53 pm - 5:14 pm
SDF
-
EYW
4h 21m
1 stop
$323Delta
Sat, Sep 5 - Sat, Sep 12
American Airlines Logo
1:41 pm - 11:00 pm
EYW
-
SDF
9h 19m
2 stops
American Airlines Logo
6:06 am - 11:45 am
SDF
-
EYW
5h 39m
1 stop
$328American Airlines
Sat, Sep 5 - Sat, Sep 12
Delta Logo
6:00 pm - 11:59 pm
EYW
-
SDF
5h 59m
1 stop
Delta Logo
12:53 pm - 5:14 pm
SDF
-
EYW
4h 21m
1 stop
$333Delta
Sat, Sep 5 - Sat, Sep 12
American Airlines Logo
1:41 pm - 11:00 pm
EYW
-
SDF
9h 19m
2 stops
American Airlines Logo
11:16 am - 6:27 pm
SDF
-
EYW
7h 11m
2 stops
$339American Airlines
Sat, Sep 5 - Sat, Sep 12
Delta Logo
6:19 pm - 12:25 am
EYW
-
SDF
6h 06m
1 stop
Delta Logo
8:10 am - 1:28 pm
SDF
-
EYW
5h 18m
1 stop
$348Delta
Wed, Jun 3 - Tue, Jun 9
United Airlines Logo
2:26 pm - 10:50 pm
EYW
-
SDF
8h 24m
1 stop
United Airlines Logo
6:30 am - 1:30 pm
SDF
-
EYW
7h 00m
1 stop
$424United Airlines
Thu, Aug 6 - Mon, Aug 10
Multiple Airlines Logo
7:22 pm - 8:36 am
EYW
-
SDF
37h 14m
2 stops
Multiple Airlines Logo
8:28 pm - 1:58 pm
SDF
-
EYW
17h 30m
1 stop
$461Multiple Airlines
Mon, May 25 - Fri, May 29
United Airlines Logo
3:55 pm - 11:56 pm
EYW
-
SDF
8h 01m
1 stop
United Airlines Logo
7:47 pm - 1:30 pm
SDF
-
EYW
17h 43m
2 stops
$568United Airlines
Thu, Jun 4 - Tue, Jun 9
United Airlines Logo
2:26 pm - 10:50 pm
EYW
-
SDF
8h 24m
1 stop
United Airlines Logo
10:05 am - 1:29 pm
SDF
-
EYW
27h 24m
2 stops
$573United Airlines
Thu, Aug 6 - Mon, Aug 10
United Airlines Logo
3:55 pm - 11:56 pm
EYW
-
SDF
8h 01m
1 stop
United Airlines Logo
7:47 pm - 1:30 pm
SDF
-
EYW
17h 43m
2 stops
$626United Airlines
Wed, Jun 3 - Tue, Jun 9

Delta flights from Key West to Louisville

Our best Delta deals on Key West to Louisville flight tickets
Delta
Sep 5
EYW6:00 pmKey West
5h 59m
1 stop
SDF11:59 pmLouisville Intl
Sep 12
SDF12:53 pmLouisville Intl
4h 21m
1 stop
EYW5:14 pmKey West
$323
Delta
Sep 5
EYW6:00 pmKey West
5h 59m
1 stop
SDF11:59 pmLouisville Intl
Sep 12
SDF12:53 pmLouisville Intl
4h 21m
1 stop
EYW5:14 pmKey West
$333
Delta
Jun 3
EYW6:19 pmKey West
6h 06m
1 stop
SDF12:25 amLouisville Intl
Jun 9
SDF8:10 amLouisville Intl
5h 18m
1 stop
EYW1:28 pmKey West
$348

American Airlines flights from Key West to Louisville

Our best American Airlines deals on Key West to Louisville flight tickets
American Airlines
Sep 5
EYW1:41 pmKey West
9h 19m
2 stops
SDF11:00 pmLouisville Intl
Sep 12
SDF6:06 amLouisville Intl
5h 39m
1 stop
EYW11:45 amKey West
$328
American Airlines
Sep 5
EYW1:41 pmKey West
9h 19m
2 stops
SDF11:00 pmLouisville Intl
Sep 12
SDF11:16 amLouisville Intl
7h 11m
2 stops
EYW6:27 pmKey West
$339
American Airlines
May 19
EYW5:25 pmKey West
6h 05m
1 stop
SDF11:30 pmLouisville Intl
May 22
SDF12:00 pmLouisville Intl
6h 49m
1 stop
EYW6:49 pmKey West
$841

momondo Fare Finder

 
Customize your flight search to find flights from Key West to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from Key West to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sat 9/5

6:00 pm-11:59 pm

1 stop5h 59m

Louisville Intl

Sat 9/12

12:53 pm-5:14 pm

1 stop4h 21m

$323

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sat 9/5

1:41 pm-11:00 pm

2 stops9h 19m

Louisville Intl

Sat 9/12

6:06 am-11:45 am

1 stop5h 39m

$328

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sat 9/5

6:00 pm-11:59 pm

1 stop5h 59m

Louisville Intl

Sat 9/12

12:53 pm-5:14 pm

1 stop4h 21m

$333

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sat 9/5

1:41 pm-11:00 pm

2 stops9h 19m

Louisville Intl

Sat 9/12

11:16 am-6:27 pm

2 stops7h 11m

$339

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Wed 6/3

6:19 pm-12:25 am

1 stop6h 06m

Louisville Intl

Tue 6/9

8:10 am-1:28 pm

1 stop5h 18m

$348

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 8/6

2:26 pm-10:50 pm

1 stop8h 24m

Louisville Intl

Mon 8/10

6:30 am-1:30 pm

1 stop7h 00m

$424

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Mon 5/25

7:22 pm-8:36 am

2 stops37h 14m

Louisville Intl

Fri 5/29

8:28 pm-1:58 pm

1 stop17h 30m

$461

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 6/4

3:55 pm-11:56 pm

1 stop8h 01m

Louisville Intl

Tue 6/9

7:47 pm-1:30 pm

2 stops17h 43m

$568

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 8/6

2:26 pm-10:50 pm

1 stop8h 24m

Louisville Intl

Mon 8/10

10:05 am-1:29 pm

2 stops27h 24m

$573

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Wed 6/3

3:55 pm-11:56 pm

1 stop8h 01m

Louisville Intl

Tue 6/9

7:47 pm-1:30 pm

2 stops17h 43m

$626

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from Key West to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Key West to Louisville Intl?

Delta is the most popular carrier operating from Key West to Louisville Intl

When to book flights from Key West to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to Louisville (EYW to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to Louisville

Fastest flight time

5h 59m

Direct flights

None
The fastest flight from Key West to Louisville takes 5h 59m
There are no direct flights from Key West to Louisville. There are no popular flight routes from Key West to Louisville.
Search flight deals

Frequently asked questions about flying from Key West to Louisville

  • How far is Key West to Louisville Intl by plane?

    Key West and Louisville Intl are 973.5 mi apart from one another. Flights usually cover this in 5h 59m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Key West Airport to Louisville Intl Airport?

    Prices for flights from Key West Airport to Louisville Intl Airport were last updated today.

  • How old do you have to be to fly from Key West Airport to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The necessary travel and health documents for your Louisville Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
Jeffersonville
West Baden Springs
Bardstown
New Albany
Shepherdsville
Brandenburg
Corydon
Elizabeth
Charlestown
Georgetown
Springfield

Why use momondo?

Why should I use momondo to find a flight deal from Key West to Louisville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Key West to Louisville for you.

Can I find flights from Key West to Louisville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Louisville from Key West with this policy.

How can momondo help me find flights from Key West to Louisville?

momondo provides multiple filters to help you find the best flight to Louisville from Key West. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Key West to Louisville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Louisville from Key West. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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