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Cheap flights from Key West to Louisville from $126

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Key West to Louisville departing on 7/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Key West to Louisville

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:27 pm - 12:21 pm
EYW
-
SDF
16h 54m
2 stops
Multiple Airlines Logo
8:30 pm - 12:34 pm
SDF
-
EYW
16h 04m
1 stop
$293Multiple Airlines
Fri, Aug 14 - Mon, Aug 17
American Airlines Logo
2:25 pm - 10:18 pm
EYW
-
SDF
7h 53m
1 stop
American Airlines Logo
12:38 pm - 5:51 pm
SDF
-
EYW
5h 13m
1 stop
$319American Airlines
Sat, Sep 5 - Sat, Sep 12
Multiple Airlines Logo
1:14 pm - 8:36 am
EYW
-
SDF
19h 22m
2 stops
Multiple Airlines Logo
9:00 pm - 12:48 pm
SDF
-
EYW
15h 48m
1 stop
$323Multiple Airlines
Tue, Jul 14 - Sat, Jul 18
Breeze Airways Logo
11:46 am - 10:32 am
EYW
-
SDF
22h 46m
1 stop
Breeze Airways Logo
8:06 pm - 11:27 am
SDF
-
EYW
39h 21m
2 stops
$334Breeze Airways
Wed, Jul 29 - Wed, Aug 5
Delta Logo
6:18 pm - 12:26 am
EYW
-
SDF
6h 08m
1 stop
Delta Logo
1:16 pm - 7:51 pm
SDF
-
EYW
6h 35m
1 stop
$369Delta
Tue, Jul 14 - Sat, Jul 18
Multiple Airlines Logo
10:27 pm - 2:07 pm
EYW
-
SDF
15h 40m
1 stop
Multiple Airlines Logo
8:06 pm - 11:27 am
SDF
-
EYW
39h 21m
2 stops
$388Multiple Airlines
Thu, Jul 30 - Wed, Aug 5
American Airlines Logo
11:40 am - 9:59 pm
EYW
-
SDF
10h 19m
2 stops
American Airlines Logo
6:20 am - 1:11 pm
SDF
-
EYW
6h 51m
1 stop
$483American Airlines
Sat, Sep 5 - Sat, Sep 12
American Airlines Logo
10:15 am - 6:35 pm
EYW
-
SDF
8h 20m
2 stops
American Airlines Logo
6:20 am - 1:17 pm
SDF
-
EYW
6h 57m
2 stops
$567American Airlines
Sat, Sep 5 - Sat, Sep 12
American Airlines Logo
1:47 pm - 9:40 pm
EYW
-
SDF
7h 53m
2 stops
American Airlines Logo
6:05 am - 1:08 pm
SDF
-
EYW
7h 03m
2 stops
$657American Airlines
Thu, Jul 30 - Wed, Aug 5
Breeze Airways Logo
1:11 pm - 8:06 pm
EYW
-
SDF
30h 55m
2 stops
Breeze Airways Logo
8:28 pm - 11:06 am
SDF
-
EYW
38h 38m
2 stops
$705Breeze Airways
Fri, Aug 14 - Mon, Aug 17

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American Airlines flights from Key West to Louisville

Our best American Airlines deals on Key West to Louisville flight tickets
American Airlines
Sep 5
EYW2:25 pmKey West
7h 53m
1 stop
SDF10:18 pmLouisville Intl
Sep 12
SDF12:38 pmLouisville Intl
5h 13m
1 stop
EYW5:51 pmKey West
$319
American Airlines
Sep 5
EYW11:40 amKey West
10h 19m
2 stops
SDF9:59 pmLouisville Intl
Sep 12
SDF6:20 amLouisville Intl
6h 51m
1 stop
EYW1:11 pmKey West
$483
American Airlines
Sep 5
EYW10:15 amKey West
8h 20m
2 stops
SDF6:35 pmLouisville Intl
Sep 12
SDF6:20 amLouisville Intl
6h 57m
2 stops
EYW1:17 pmKey West
$567

Breeze Airways flights from Key West to Louisville

Our best Breeze Airways deals on Key West to Louisville flight tickets
Breeze Airways
Jul 29
EYW11:46 amKey West
22h 46m
1 stop
SDF10:32 amLouisville Intl
Aug 5
SDF8:06 pmLouisville Intl
39h 21m
2 stops
EYW11:27 amKey West
$334
Breeze Airways
Aug 14
EYW1:11 pmKey West
30h 55m
2 stops
SDF8:06 pmLouisville Intl
Aug 17
SDF8:28 pmLouisville Intl
38h 38m
2 stops
EYW11:06 amKey West
$705
Breeze Airways
Jul 30
EYW12:05 pmKey West
21h 50m
3 stops
SDF9:55 amLouisville Intl
Aug 5
SDF8:06 pmLouisville Intl
23h 07m
2 stops
EYW7:13 pmKey West
$749

momondo Fare Finder

 
Customize your flight search to find flights from Key West to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 2, 2026.
Use the filters below to find and compare flights from Key West to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Fri 8/14

7:27 pm-12:21 pm

2 stops16h 54m

Louisville Intl

Mon 8/17

8:30 pm-12:34 pm

1 stop16h 04m

$293

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sat 9/5

2:25 pm-10:18 pm

1 stop7h 53m

Louisville Intl

Sat 9/12

12:38 pm-5:51 pm

1 stop5h 13m

$319

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Tue 7/14

1:14 pm-8:36 am

2 stops19h 22m

Louisville Intl

Sat 7/18

9:00 pm-12:48 pm

1 stop15h 48m

$323

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Wed 7/29

11:46 am-10:32 am

1 stop22h 46m

Louisville Intl

Wed 8/5

8:06 pm-11:27 am

2 stops39h 21m

$334
Quickest round-trip

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Tue 7/14

6:18 pm-12:26 am

1 stop6h 08m

Louisville Intl

Sat 7/18

1:16 pm-7:51 pm

1 stop6h 35m

$369

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 7/30

10:27 pm-2:07 pm

1 stop15h 40m

Louisville Intl

Wed 8/5

8:06 pm-11:27 am

2 stops39h 21m

$388

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sat 9/5

11:40 am-9:59 pm

2 stops10h 19m

Louisville Intl

Sat 9/12

6:20 am-1:11 pm

1 stop6h 51m

$483

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Sat 9/5

10:15 am-6:35 pm

2 stops8h 20m

Louisville Intl

Sat 9/12

6:20 am-1:17 pm

2 stops6h 57m

$567

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Thu 7/30

1:47 pm-9:40 pm

2 stops7h 53m

Louisville Intl

Wed 8/5

6:05 am-1:08 pm

2 stops7h 03m

$657

Key WestLouisville

EYW - SDF

EYWSDF

Key West

Fri 8/14

1:11 pm-8:06 pm

2 stops30h 55m

Louisville Intl

Mon 8/17

8:28 pm-11:06 am

2 stops38h 38m

$705

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Louisville from

How to get the cheapest flight ticket from Key West to Louisville

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Key West to Louisville Intl?

Breeze Airways and Delta are the most popular carriers operating from Key West to Louisville Intl

When to book flights from Key West to Louisville

Are you open to changing your travel dates? Check out the ideal times to fly from Key West to Louisville according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Key West to Louisville (EYW to SDF) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Key West to Louisville

Fastest flight time

6h 08m

Direct flights

None
The fastest flight from Key West to Louisville takes 6h 08m
There are no direct flights from Key West to Louisville. There are no popular flight routes from Key West to Louisville.
Search flight deals

Frequently asked questions about flying from Key West to Louisville

  • How far is Key West to Louisville Intl by plane?

    Key West and Louisville Intl are 973.5 mi apart from one another. Flights usually cover this in 6h 08m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Key West Airport to Louisville Intl Airport?

    Prices for flights from Key West Airport to Louisville Intl Airport were last updated today.

  • How old do you have to be to fly from Key West Airport to Louisville Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Key West Airport to Louisville Intl Airport.

  • What documentation or ID do you need to fly to Louisville Intl Airport?

    The necessary travel and health documents for your Louisville Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
French Lick
Elizabethtown
Jeffersonville
West Baden Springs
Bardstown
Shepherdsville
New Albany
Elizabeth
Charlestown
Corydon
Brandenburg
Georgetown
Springfield

Why use momondo?

Why should I use momondo to find a flight deal from Key West to Louisville?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Key West to Louisville for you.

Can I find flights from Key West to Louisville with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Louisville from Key West with this policy.

How can momondo help me find flights from Key West to Louisville?

momondo provides multiple filters to help you find the best flight to Louisville from Key West. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Key West to Louisville right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Louisville from Key West. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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